- Must visit
The Children's Museum of Indianapolis
World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.
Cheapest price on Sep 19
$48
Average ticket price on Sep 19
$52
Fastest journey on Sep 19
7 h 15 m
Average journey duration on Sep 19
8 h 2 m
Buses on Sep 19
6
Distance
529 km
The best way to find a cheap bus ticket from Pittsburgh, PA to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pittsburgh, PA to Indianapolis, IN will cost around $52 if you buy it on the day, but the cheapest tickets can be found for only $48.
On Sat, Sep 19, we found 6 buses from Pittsburgh, PA to Indianapolis, IN, including 5 direct services.
On Sat, Sep 19 the direct buses cover the 529 km distance in an average of 8 h 2 m but if you time it right, some buses will get you there in just 7 h 15 m .
On Sat, Sep 19 the slowest buses will take 9 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus

FlixBus
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FlixBus
FlixBus


FlixBusOmio recommends booking the bus as it is the most popular option from Pittsburgh, PA to Indianapolis, IN among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $70 For those with little time, consider booking a flight, which has an average total journey time of 5h 52m. Average ticket prices depend on the travel mode: a bus costs an average of $70, while a flight costs an average of $583.
Distance: 328 miles (529 km)
Most popular Bus | Train | Flight |
|---|---|---|
$70 Average price Cheapest | $249 Average price | $583 Average price |
9h 21m Average total duration 8h 51m Onboard + 30m Additional time* | 15h 10m Average total duration 14h 40m Onboard + 30m Additional time* | 5h 52m Average total duration Fastest 3h 52m Onboard + 2h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Pittsburgh, PA to Indianapolis, IN:
A bus is $178 less than a train for this route with tickets for a train from Pittsburgh, PA to Indianapolis, IN costing on average $249.
A bus is $513 less than a flight for this route with tickets for a flight from Pittsburgh, PA to Indianapolis, IN costing on average $583.
Other travel options to Indianapolis, IN take longer:
Bus takes on average 8h 51m.
Train takes on average 14h 40m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:55AM | Arrival Time 03:00PM | Duration 14h05 | Departure days Everyday | Cheapest price $49 |
Operator Greyhound | Departure Time 01:25AM | Arrival Time 09:20AM | Duration 7h55 | Departure days Everyday | Cheapest price $42 |
Operator FlixBus | Departure Time 07:00AM | Arrival Time 04:00PM | Duration 9h00 | Departure days Mon, Sat, Sun | Cheapest price $48 |
Operator Greyhound | Departure Time 10:20AM | Arrival Time 06:10PM | Duration 7h50 | Departure days Everyday | Cheapest price $43 |
Operator FlixBus | Departure Time 07:45PM | Arrival Time 03:00AM | Duration 7h15 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $42 |
Operator Greyhound | Departure Time 08:00PM | Arrival Time 04:10AM | Duration 8h10 | Departure days Everyday | Cheapest price $42 |
The table below shows live departures for Pittsburgh, PA to Indianapolis, IN buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 7:45 PM Pittsburgh, Greyhound Bus Station, PA | 7h15 | 3:00 AM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 0 transfersDirect | |
![]() | 8:00 PM Pittsburgh, Greyhound Bus Station, PA | 8h10 | 4:10 AM Indianapolis, Illinois St (Greyhound Bus Station) | 0 transfersDirect | |
| Saturday, September 19 | |||||
+ FlixBus | 12:55 AM Pittsburgh, Greyhound Bus Station, PA | 14h05 | 3:00 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 1 transfer | |
![]() | 1:25 AM Pittsburgh, Greyhound Bus Station, PA | 7h55 | 9:20 AM Indianapolis, Illinois St (Greyhound Bus Station) | 0 transfersDirect | |
FlixBus | 7:00 AM Pittsburgh, Greyhound Bus Station, PA | 9h00 | 4:00 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 0 transfersDirect | |
![]() | 10:20 AM Pittsburgh, Greyhound Bus Station, PA | 7h50 | 6:10 PM Indianapolis, Illinois St (Greyhound Bus Station) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Pittsburgh, PA to Indianapolis, IN run on average 6 times per day, taking around 8h 51m. Cheap bus tickets for this journey start at $43 if you book in advance.
There are 5 buses per day. The earliest bus runs at 00:15, the last at 20:10. The fastest bus covers the 328 miles (529 km) distance in 7h 15m.
Distance 328 miles (529 km) |
Average bus duration 8h 51m |
Cheapest ticket price $43 |
Buses per day 6 |
Direct buses 5 |
Fastest bus 7h 15m |
First bus 12:15 AM |
Last bus 8:10 PM |
Cheapest Month May |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 14 days |
Discover the best of Indianapolis, IN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis, IN trip today.
World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.
Leading art museum set on the Newfields campus, with major collections from Europe, Asia, Africa, and America plus temporary exhibitions.
Museum and restored home of the 23rd U.S. president. Guided visits reveal politics, domestic life, and architecture from the late 1800s.
Pedestrian-friendly downtown canal lined with museums, public art, and boats. Ideal for a scenic walk and one of the city's most popular areas.
Historic city center surrounding the Soldiers and Sailors Monument. A signature urban space for architecture, events, and classic downtown views.
Popular cultural trail linking downtown districts with public art, bike lanes, and green streetscape design. Perfect for exploring the city on foot.
Indiana pork tenderloin sandwich is a breaded, fried cutlet served on a bun, often comically oversized. It is a beloved statewide classic common in Indianapolis pubs and diners.
Sugar cream pie is Indiana's state pie, made with cream, sugar, and nutmeg. Its simple farm-pantry origins make it a traditional Hoosier dessert tied closely to local identity.
Shrimp cocktail in Indianapolis style features chilled shrimp with very spicy tomato-horseradish sauce. St. Elmo made this fiery version a city dining icon.
Established fine-dining restaurant serving seasonal Midwestern cuisine with polished service. Known for refined plates and a warm, contemporary atmosphere.
Historic downtown steakhouse famous for aged steaks and the city's iconic fiery shrimp cocktail. Classic, upscale atmosphere with longstanding local prestige.
Long-running Indianapolis institution known for classic steaks, seafood, and old-school service. A traditional downtown choice with historic local character.
Moderate for a U.S. city: hotels and dining are mid-range, while transit is limited so many visitors use rideshare or rental cars.
Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Small cafe tips are appreciated but optional.
Find answers to the most common questions about traveling from Pittsburgh, PA to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

Most Pittsburgh, PA to Indianapolis, IN buses use the Pittsburgh, Greyhound Bus Station to Indianapolis, Illinois St (Greyhound Bus Station) station pair. Use this guide to compare Pittsburgh, PA and Indianapolis, IN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Pittsburgh, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack bar available on site
Available throughout the station. ATMs are aTM located near the entrance.
Ticket office support is available at Pittsburgh, Greyhound Bus Station.
Available at Pittsburgh, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Pittsburgh, Greyhound Bus Station: Wheelchair accessible entrances.
Indianapolis, Illinois St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Fast food outlets are available.
Free Wi-Fi is available throughout the station. ATMs are aTM is located near the entrance.
Ticket office support is available at Indianapolis, Illinois St (Greyhound Bus Station).
Available at Indianapolis, Illinois St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Indianapolis, Illinois St (Greyhound Bus Station): The station is wheelchair accessible.
Here are some other resources that might have the information you need