- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Cheapest price on Sep 01
$43
Average ticket price on Sep 01
$60
Fastest journey on Sep 01
10 h 15 m
Average journey duration on Sep 01
12 h 28 m
Buses on Sep 01
5
Distance
516 km
The best way to find a cheap bus ticket from Nantes to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Nantes to Lyon will cost around $60 if you buy it on the day, but the cheapest tickets can be found for only $43.
On Tue, Sep 01, we found 5 buses from Nantes to Lyon, including 1 direct services.
On Tue, Sep 01 the direct buses cover the 516 km distance in an average of 12 h 28 m but if you time it right, some buses will get you there in just 10 h 15 m .
On Tue, Sep 01 the slowest buses will take 14 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
87086 · 4787
87086 · 5133
FlixBus · FlixBus
FlixBus
FlixBus · FlixBus
FlixBus
87086 · 5133
87086 · 4787
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the train as it is the most popular option from Nantes to Lyon among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $74 For those with little time, consider booking a flight, which has an average total journey time of 4h 15m. Average ticket prices depend on the travel mode: a bus costs an average of $74, while a flight costs an average of $468.
Distance: 320 miles (516 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$74 Average price Cheapest | $154 Average price | $468 Average price | $222 Average price (fuel + tolls) |
11h 27m Average total duration 10h 57m Onboard + 30m Additional time* | 5h 18m Average total duration 4h 48m Onboard + 30m Additional time* | 4h 15m Average total duration Fastest 2h 15m Onboard + 2h 0m Additional time* | 6h 34m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Nantes to Lyon:
A bus is $80 (€65) less than a train for this route with tickets for a train from Nantes to Lyon costing on average $154 (€124).
A bus is $394 (€319) less than a flight for this route with tickets for a flight from Nantes to Lyon costing on average $468 (€379).
Other travel options to Lyon take longer:
Train takes on average 4h 48m.
Bus takes on average 10h 57m.
Tickets start at around $74 (€60) compared to roughly $222 (€180) in fuel and tolls — a saving of about $149 (€120). The journey takes 10h 57m versus 6h 34m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar Bus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:20AM | Arrival Time 12:55PM | Duration 12h35 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $60 |
Operator FlixBus | Departure Time 12:30AM | Arrival Time 02:45PM | Duration 14h15 | Departure days Tue, Thu, Sat | Cheapest price $49 |
Operator BlaBlaCar Bus | Departure Time 05:30AM | Arrival Time 06:50PM | Duration 13h20 | Departure days Wed | Cheapest price $53 |
Operator BlaBlaCar | Departure Time 06:00AM | Arrival Time 01:20PM | Duration 7h20 | Departure days Fri | Cheapest price $81 |
Operator BlaBlaCar | Departure Time 06:10AM | Arrival Time 01:30PM | Duration 7h20 | Departure days Sat | Cheapest price $43 |
Operator BlaBlaCar | Departure Time 06:30AM | Arrival Time 01:30PM | Duration 7h00 | Departure days Tue | Cheapest price $63 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 04:40PM | Duration 8h40 | Departure days Thu, Sat | Cheapest price $53 |
Operator FlixBus | Departure Time 08:10AM | Arrival Time 06:15PM | Duration 10h05 | Departure days Fri, Sat, Sun | Cheapest price $35 |
Operator BlaBlaCar | Departure Time 08:40AM | Arrival Time 04:00PM | Duration 7h20 | Departure days Thu | Cheapest price $53 |
Operator BlaBlaCar | Departure Time 08:50AM | Arrival Time 05:40PM | Duration 8h50 | Departure days Wed, Sat | Cheapest price $71 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 03:10PM | Duration 6h10 | Departure days Wed, Sun | Cheapest price $51 |
Operator BlaBlaCar | Departure Time 09:10AM | Arrival Time 04:10PM | Duration 7h00 | Departure days Thu, Sun | Cheapest price $48 |
Operator BlaBlaCar Bus | Departure Time 09:45AM | Arrival Time 10:05PM | Duration 12h20 | Departure days Thu, Sun | Cheapest price $65 |
Operator BlaBlaCar | Departure Time 10:20AM | Arrival Time 05:30PM | Duration 7h10 | Departure days Sun | Cheapest price $57 |
Operator FlixBus | Departure Time 10:45AM | Arrival Time 11:50PM | Duration 13h05 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $51 |
Operator BlaBlaCar | Departure Time 10:50AM | Arrival Time 05:40PM | Duration 6h50 | Departure days Sat | Cheapest price $57 |
Operator BlaBlaCar | Departure Time 11:00AM | Arrival Time 05:20PM | Duration 6h20 | Departure days Wed | Cheapest price $67 |
Operator BlaBlaCar | Departure Time 11:30AM | Arrival Time 07:20PM | Duration 7h50 | Departure days Tue | Cheapest price $81 |
Operator BlaBlaCar | Departure Time 11:40AM | Arrival Time 06:50PM | Duration 7h10 | Departure days Fri | Cheapest price $67 |
Operator BlaBlaCar Bus | Departure Time 11:55AM | Arrival Time 12:20AM | Duration 12h25 | Departure days Thu, Fri, Sat, Sun | Cheapest price $28 |
Operator BlaBlaCar | Departure Time 12:00PM | Arrival Time 06:20PM | Duration 6h20 | Departure days Tue | Cheapest price $59 |
Operator BlaBlaCar | Departure Time 12:10PM | Arrival Time 08:30PM | Duration 8h20 | Departure days Wed | Cheapest price $60 |
Operator FlixBus | Departure Time 12:40PM | Arrival Time 03:10AM | Duration 14h30 | Departure days Mon, Sat | Cheapest price $51 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 01:10AM | Duration 12h25 | Departure days Fri, Sun | Cheapest price $56 |
Operator BlaBlaCar | Departure Time 01:00PM | Arrival Time 08:10PM | Duration 7h10 | Departure days Mon, Sun | Cheapest price $43 |
Operator BlaBlaCar | Departure Time 01:10PM | Arrival Time 07:20PM | Duration 6h10 | Departure days Thu | Cheapest price $50 |
Operator BlaBlaCar Bus | Departure Time 01:40PM | Arrival Time 01:40AM | Duration 12h00 | Departure days Mon | Cheapest price $86 |
Operator BlaBlaCar | Departure Time 02:00PM | Arrival Time 09:20PM | Duration 7h20 | Departure days Tue | Cheapest price $52 |
Operator BlaBlaCar | Departure Time 02:30PM | Arrival Time 10:00PM | Duration 7h30 | Departure days Mon | Cheapest price $61 |
Operator FlixBus | Departure Time 04:30PM | Arrival Time 05:20AM | Duration 12h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $52 |
Operator BlaBlaCar Bus | Departure Time 05:00PM | Arrival Time 05:20AM | Duration 12h20 | Departure days Everyday | Cheapest price $31 |
Operator BlaBlaCar | Departure Time 05:40PM | Arrival Time 01:50AM | Duration 8h10 | Departure days Sat | Cheapest price $62 |
Operator FlixBus | Departure Time 05:45PM | Arrival Time 05:55AM | Duration 12h10 | Departure days Mon | Cheapest price $85 |
Operator FlixBus | Departure Time 08:35PM | Arrival Time 06:50AM | Duration 10h15 | Departure days Everyday | Cheapest price $41 |
Operator BlaBlaCar Bus | Departure Time 11:35PM | Arrival Time 08:45AM | Duration 9h10 | Departure days Mon, Fri, Sat, Sun | Cheapest price $40 |
The table below shows live departures for Nantes to Lyon buses for today, Monday, August 31. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 12:40 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 14h30 | 3:10 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
50816 · 4781 | 1:40 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h00 | 1:40 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 4:30 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h50 | 5:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
87086 · 4787 | 5:00 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h25 | 5:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
87086 · 50883 | 5:00 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h25 | 5:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
87086 · 5133 | 5:00 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h20 | 5:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 5:45 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h10 | 5:55 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 8:35 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 10h15 | 6:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
72404 | 11:35 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 9h10 | 8:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| Tuesday, September 1 | |||||
FlixBus · FlixBus | 12:30 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 14h15 | 2:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 10:45 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 13h05 | 11:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Nantes to Lyon run on average 11 times per day, taking around 10h 57m. Cheap bus tickets for this journey start at $27 (€21) if you book in advance.
There are 2 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 320 miles (516 km) distance in 8h 10m.
Distance 320 miles (516 km) |
Average bus duration 10h 57m |
Cheapest ticket price $27 (€21) |
Buses per day 11 |
Direct buses 2 |
Fastest bus 8h 10m |
First bus 12:05 AM |
Last bus 11:55 PM |
Cheapest Month May |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Fri |
Best time to book 21 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Museum of cinema miniatures and film props in Vieux Lyon. Popular for detailed sets, special-effects history, and family-friendly exhibits.
Excellent free natural history and ethnography museum with fossils, animals, and global cultures. A strong local favorite, especially for families.
Renaissance quarter with cobbled lanes, traboules, courtyards, and major monuments. Essential for atmosphere, history, and walking exploration.
Central peninsula between the Rhône and Saône, packed with elegant streets, squares, shopping, and many of Lyon’s classic city views.
Historic silk-workers’ hill district with stairways, murals, markets, and hidden passageways. Great for local character and city panoramas.
Pike dumplings in a rich crayfish sauce. A Lyon classic from traditional bouchons, prized for its delicate fish texture and luxurious sauce.
Crisp salad of frisée, bacon lardons, croutons, and a poached egg. A staple Lyonnaise bistro dish that reflects the city's hearty cooking style.
Slow-cooked onions with vinegar, often served warm or chilled. This old Lyonnais side dish is traditional in bouchons and pairs well with charcuterie.
Refined dining by Paul Bocuse, known for polished French cuisine and iconic Lyon dishes in an elegant, historic dining room.
Well-known traditional bouchon in Vieux Lyon, praised for generous Lyonnais specialties and a lively old-city atmosphere.
Historic bouchon near Place Bellecour serving quenelles, salade lyonnaise, and classic regional fare in a warm traditional setting.
Moderate for Western Europe: hotels and dining are mid-priced, while public transport is good value for visitors.
Service is usually included. Round up or leave 5-10% for great restaurant service. Round up taxi fares; small change is fine in cafes.
Find answers to the most common questions about traveling from Nantes to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most Nantes to Lyon buses use the Nantes, Route de Paris to Lyon, Gare Routière de Perrache station pair, with some services arriving at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). Use this guide to compare Nantes and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Nantes, Route de Paris is 4 km from Nantes city centre. Public transport options include:
Nantes, Route de Paris has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Fast Food Express (in the station).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Nantes, Route de Paris.
Available at Nantes, Route de Paris: Parking, Taxis, WC.
Accessibility facilities are available at Nantes, Route de Paris: Elevators, ramps.
Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Nearby cafes and restaurants available.
Wi-Fi is available at Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes. ATMs are aTM available near the station.
Ticket office support is available at Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes.
Available at Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes: Parking, Taxis, WC.
Accessibility facilities are available at Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes: Accessible for wheelchair users.
Nantes, Boulevard de Berlin (Pôle d'échange multimodal Gare Sud SNCF) is 1 km from Nantes city centre. Public transport options include:
Nantes, Boulevard de Berlin (Pôle d'échange multimodal Gare Sud SNCF) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several small eateries located nearby.
Wi-Fi is available at Nantes, Boulevard de Berlin (Pôle d'échange multimodal Gare Sud SNCF). ATMs are located near the ticket office.
Ticket office support is available at Nantes, Boulevard de Berlin (Pôle d'échange multimodal Gare Sud SNCF).
Available at Nantes, Boulevard de Berlin (Pôle d'échange multimodal Gare Sud SNCF): Parking, Taxis, WC.
Accessibility facilities are available at Nantes, Boulevard de Berlin (Pôle d'échange multimodal Gare Sud SNCF): Wheelchair accessible with ramps and elevators.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, St Exupéry Aéroport is 2 km from Lyon city centre. Public transport options include:
Lyon, St Exupéry Aéroport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, St Exupéry Aéroport. ATMs are available at Lyon, St Exupéry Aéroport.
Ticket office support is available at Lyon, St Exupéry Aéroport.
Available at Lyon, St Exupéry Aéroport: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, St Exupéry Aéroport: Access ramps and services available.
Here are some other resources that might have the information you need