- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Cheapest price
$58
Average price
$98
Fastest journey
9 h 10 m
Average duration
10 h 42 m
Buses per day
19
Distance
516 km
The best way to find a cheap bus ticket from Nantes to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Nantes to Lyon will cost around $98 if you buy it on the day, but the cheapest tickets can be found for only $58.
Of the 19 buses that leave Nantes for Lyon on Sat, Jul 18, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jul 18 the direct buses cover the 516 km distance in an average of 10 h 42 m but if you time it right, some buses will get you there in just 9 h 10 m .
On Sat, Jul 18 the slowest buses will take 12 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
88094 · 50107
50816 · 4781
72404
90400 · 7465
FlixBus
72404
FlixBus
FlixBus
50816 · 4781
FlixBus · FlixBusOmio recommends booking the train as it is the most popular option from Nantes to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $27. For those with little time consider booking a flight which can get you there in 1h 23m. The ticket price range depends on the travel mode: a bus costs an average of $27, and a flight costs an average of $59.
Distance: 320 miles (516 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$60 Average price Cheapest | $98 Average price | $146 Average price | $218 Average price (fuel + tolls) |
9h 13m Average total duration 8h 43m Onboard + 30m Additional time* | 6h 49m Average total duration 6h 19m Onboard + 30m Additional time* | 4h 23m Average total duration Fastest 1h 23m Onboard + 3h 0m Additional time* | 6h 34m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Nantes to Lyon:
A bus is $37 (€31) less than a train for this route with tickets for a train from Nantes to Lyon costing on average $98 (€80).
A bus is $86 (€70) less than a flight for this route with tickets for a flight from Nantes to Lyon costing on average $146 (€120).
Other travel options to Lyon take longer:
Train takes on average 6h 19m.
Bus takes on average 8h 43m.
Tickets start at around $60 (€50) compared to roughly $218 (€179) in fuel and tolls — a saving of about $158 (€129). The journey takes 8h 43m versus 6h 34m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar Bus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:20AM | Arrival Time 12:55PM | Duration 12h35 | Departure days Mon, Tue, Wed, Thu, Sat | Cheapest price $93 |
Operator FlixBus | Departure Time 12:30AM | Arrival Time 02:45PM | Duration 14h15 | Departure days Mon, Tue, Thu, Sat | Cheapest price $60 |
Operator BlaBlaCar | Departure Time 06:30AM | Arrival Time 01:40PM | Duration 7h10 | Departure days Sun | Cheapest price $71 |
Operator BlaBlaCar | Departure Time 07:00AM | Arrival Time 02:00PM | Duration 7h00 | Departure days Tue, Thu, Sat, Sun | Cheapest price $69 |
Operator BlaBlaCar | Departure Time 07:30AM | Arrival Time 04:40PM | Duration 9h10 | Departure days Thu | Cheapest price $52 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 09:10PM | Duration 13h40 | Departure days Tue, Wed | Cheapest price $61 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 03:10PM | Duration 7h10 | Departure days Fri | Cheapest price $63 |
Operator FlixBus | Departure Time 08:10AM | Arrival Time 06:15PM | Duration 10h05 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $61 |
Operator BlaBlaCar | Departure Time 08:20AM | Arrival Time 02:50PM | Duration 6h30 | Departure days Thu | Cheapest price $67 |
Operator BlaBlaCar | Departure Time 08:50AM | Arrival Time 06:00PM | Duration 9h10 | Departure days Fri | Cheapest price $58 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 02:50PM | Duration 5h50 | Departure days Tue, Fri | Cheapest price $59 |
Operator BlaBlaCar | Departure Time 09:10AM | Arrival Time 06:50PM | Duration 9h40 | Departure days Mon, Tue | Cheapest price $76 |
Operator BlaBlaCar | Departure Time 09:30AM | Arrival Time 04:50PM | Duration 7h20 | Departure days Wed | Cheapest price $47 |
Operator BlaBlaCar | Departure Time 09:40AM | Arrival Time 04:00PM | Duration 6h20 | Departure days Sun | Cheapest price $67 |
Operator BlaBlaCar Bus | Departure Time 09:45AM | Arrival Time 10:05PM | Duration 12h20 | Departure days Wed, Thu, Sat, Sun | Cheapest price $46 |
Operator BlaBlaCar | Departure Time 09:50AM | Arrival Time 06:40PM | Duration 8h50 | Departure days Sun | Cheapest price $72 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 05:40PM | Duration 7h40 | Departure days Sat | Cheapest price $71 |
Operator FlixBus | Departure Time 10:10AM | Arrival Time 11:15PM | Duration 13h05 | Departure days Mon, Thu, Sat | Cheapest price $60 |
Operator BlaBlaCar | Departure Time 10:10AM | Arrival Time 05:10PM | Duration 7h00 | Departure days Sat | Cheapest price $64 |
Operator BlaBlaCar | Departure Time 10:20AM | Arrival Time 05:40PM | Duration 7h20 | Departure days Thu, Sat | Cheapest price $52 |
Operator FlixBus | Departure Time 10:45AM | Arrival Time 11:50PM | Duration 13h05 | Departure days Everyday | Cheapest price $60 |
Operator BlaBlaCar Bus | Departure Time 11:55AM | Arrival Time 12:20AM | Duration 12h25 | Departure days Everyday | Cheapest price $30 |
Operator BlaBlaCar | Departure Time 12:30PM | Arrival Time 07:40PM | Duration 7h10 | Departure days Sat, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 12:40PM | Arrival Time 03:10AM | Duration 14h30 | Departure days Mon | Cheapest price $191 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 01:05AM | Duration 12h20 | Departure days Fri, Sat, Sun | Cheapest price $90 |
Operator BlaBlaCar | Departure Time 01:30PM | Arrival Time 08:40PM | Duration 7h10 | Departure days Fri | Cheapest price $77 |
Operator BlaBlaCar Bus | Departure Time 01:40PM | Arrival Time 01:40AM | Duration 12h00 | Departure days Everyday | Cheapest price $39 |
Operator FlixBus | Departure Time 01:40PM | Arrival Time 02:20AM | Duration 12h40 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $60 |
Operator BlaBlaCar | Departure Time 02:20PM | Arrival Time 09:40PM | Duration 7h20 | Departure days Mon | Cheapest price $77 |
Operator FlixBus | Departure Time 04:30PM | Arrival Time 04:35AM | Duration 12h05 | Departure days Everyday | Cheapest price $61 |
Operator BlaBlaCar Bus | Departure Time 05:00PM | Arrival Time 05:25AM | Duration 12h25 | Departure days Everyday | Cheapest price $30 |
Operator BlaBlaCar Bus | Departure Time 05:25PM | Arrival Time 06:10AM | Duration 12h45 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $64 |
Operator FlixBus | Departure Time 05:45PM | Arrival Time 05:45AM | Duration 12h00 | Departure days Sat, Sun | Cheapest price $97 |
Operator BlaBlaCar | Departure Time 06:20PM | Arrival Time 01:20AM | Duration 7h00 | Departure days Tue | Cheapest price $49 |
Operator FlixBus | Departure Time 08:35PM | Arrival Time 06:50AM | Duration 10h15 | Departure days Everyday | Cheapest price $60 |
Operator BlaBlaCar Bus | Departure Time 11:35PM | Arrival Time 08:45AM | Duration 9h10 | Departure days Everyday | Cheapest price $55 |
Operator FlixBus | Departure Time 11:55PM | Arrival Time 02:35PM | Duration 14h40 | Departure days Tue, Wed | Cheapest price $64 |
The table below shows live departures for Nantes to Lyon buses for today, Friday, July 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 10:45 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 13h05 | 11:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
88094 · 50107 | 11:55 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h25 | 12:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 12:45 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h20 | 1:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 1:40 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h40 | 2:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
50816 · 4781 | 1:40 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h00 | 1:40 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 4:30 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h05 | 4:35 AM Lyon | 1 transfer | |
FlixBus · FlixBus | 4:30 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h20 | 4:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
87086 · 4787 | 5:00 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h25 | 5:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
87086 · 50883 | 5:00 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h25 | 5:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
87086 · 5133 | 5:00 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h20 | 5:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
90400 · 7465 | 5:25 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h45 | 6:10 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 8:35 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 10h15 | 6:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
72404 | 11:35 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 9h10 | 8:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| Saturday, July 18 | |||||
FlixBus · FlixBus | 12:20 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h35 | 12:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 12:30 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 14h15 | 2:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 8:10 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 10h05 | 6:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Nantes to Lyon run on average 11 times per day, taking around 8h 43m. Cheap bus tickets for this journey start at $27 (€22) if you book in advance.
There are 4 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 320 miles (516 km) distance in 9h 10m.
Distance 320 miles (516 km) |
Average bus duration 8h 43m |
Cheapest ticket price $27 (€22) |
Buses per day 11 |
Direct buses 4 |
Fastest bus 9h 10m |
First bus 12:05 AM |
Last bus 11:55 PM |
Cheapest Month Oct |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 77 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Museum of cinema miniatures and film props in Vieux Lyon. Popular for detailed sets, special-effects history, and family-friendly exhibits.
Excellent free natural history and ethnography museum with fossils, animals, and global cultures. A strong local favorite, especially for families.
Renaissance quarter with cobbled lanes, traboules, courtyards, and major monuments. Essential for atmosphere, history, and walking exploration.
Central peninsula between the Rhône and Saône, packed with elegant streets, squares, shopping, and many of Lyon’s classic city views.
Historic silk-workers’ hill district with stairways, murals, markets, and hidden passageways. Great for local character and city panoramas.
Pike dumplings in a rich crayfish sauce. A Lyon classic from traditional bouchons, prized for its delicate fish texture and luxurious sauce.
Crisp salad of frisée, bacon lardons, croutons, and a poached egg. A staple Lyonnaise bistro dish that reflects the city's hearty cooking style.
Slow-cooked onions with vinegar, often served warm or chilled. This old Lyonnais side dish is traditional in bouchons and pairs well with charcuterie.
Refined dining by Paul Bocuse, known for polished French cuisine and iconic Lyon dishes in an elegant, historic dining room.
Well-known traditional bouchon in Vieux Lyon, praised for generous Lyonnais specialties and a lively old-city atmosphere.
Historic bouchon near Place Bellecour serving quenelles, salade lyonnaise, and classic regional fare in a warm traditional setting.
Moderate for Western Europe: hotels and dining are mid-priced, while public transport is good value for visitors.
Service is usually included. Round up or leave 5-10% for great restaurant service. Round up taxi fares; small change is fine in cafes.
Find answers to the most common questions about traveling from Nantes to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

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