Travel Information
Compare train, bus, and flight for Nantes to Lyon
Omio recommends booking the train as it is the most popular option from Nantes to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $28. For those with little time consider booking a flight which can get you there in 1h 23m. The ticket price range depends on the travel mode: a bus costs an average of $28, and a flight costs an average of $60.
Distance: 320 miles (516 km)
Compare train with
Most popular Train | Flight | Bus | Driving |
|---|---|---|---|
$99 Average price | $148 Average price | $61 Average price Cheapest | $221 Average price (fuel + tolls) |
6h 49m Average total duration 6h 19m Onboard + 30m Additional time* | 4h 23m Average total duration Fastest 1h 23m Onboard + 3h 0m Additional time* | 9h 13m Average total duration 8h 43m Onboard + 30m Additional time* | 6h 34m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Nantes to Lyon:
A bus is $38 (€31) less than a train for this route with tickets for a train from Nantes to Lyon costing on average $99 (€80).
A bus is $87 (€70) less than a flight for this route with tickets for a flight from Nantes to Lyon costing on average $148 (€120).
Other travel options to Lyon take longer:
Train takes on average 6h 19m.
Bus takes on average 8h 43m.
Travel optionsfrom Nantes to Lyon
How to get from Nantes to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Nantes to Lyon is by taking a bus because it’s the best combination of price and speed.
FlixBus8:35 PM10h15Nantes6:50 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$621One-way0 transfers
Cheapest
FlixBus8:35 PM10h15Nantes6:50 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$621One-way0 transfers
Fastest
EC47156:45 PM1h10Nantes Atlantique Airport7:55 PMLyon Saint Exupery Airport$1761One-way0 transfers
Other options
44062:46 PM6h40Nantes station9:26 PMLyon Part Dieu$891One-way0 transfers
53205:04 PM4h26Nantes station9:30 PMLyon Part Dieu$991One-way0 transfers
440411:48 AM6h38Nantes station6:26 PMLyon Part Dieu$1061One-way0 transfers
7240411:35 PM9h10Nantes8:45 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$621One-way0 transfers
FlixBus8:10 AM10h05Nantes6:15 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$711One-way0 transfers
87086 · 47875:00 PM12h25Nantes5:25 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$801One-way1 transfer
AF7505 · AF73702:20 PM7h05Nantes Atlantique Airport9:25 PMLyon Saint Exupery Airport$2351One-way1 transfer
EC47117:00 AM1h15Nantes Atlantique Airport8:15 AMLyon Saint Exupery Airport$3561One-way0 transfers
AF61452:30 PM1h10Nantes Atlantique Airport3:40 PMLyon Saint Exupery Airport$4041One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Nantes to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Nantes to Lyon.

This is compared to other travel options from Nantes to Lyon:
A bus is $38 (€31) less than a train for this route with tickets for a train from Nantes to Lyon costing on average $99 (€80).
A bus is $87 (€70) less than a flight for this route with tickets for a flight from Nantes to Lyon costing on average $148 (€120).
Other travel options to Lyon take longer:
Train takes on average 6h 19m.
Bus takes on average 8h 43m.
- Around 11 trains per day.
- Around 11 buses per day.
- Around 10 flights per day.
However, we recommend checking specific travel dates for your route between Nantes and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Nantes Atlantique Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Nantes station and arrive in Lyon Part Dieu.
- Buses mostly depart from Nantes, Route de Paris and arrive in Lyon, Perrache Bus Station.
- Travel with FlixBus, BlaBlaCar Bus, BlaBlaCar, Naolib to go to Lyon by bus.
- Travel with easyJet, Volotea, Air France to go to Lyon by flight.
- Travel with SNCF | Intercités, SNCF | TGV INOUI, TGV, Société Nationale des Chemins de fer Français (SNCF) to go to Lyon by train.
- 4 direct buses per day with FlixBus, BlaBlaCar Bus, BlaBlaCar.
- 2 direct flights per day with easyJet, Volotea, Air France.
- 4 direct trains per day with SNCF | Intercités, SNCF | TGV INOUI, Société Nationale des Chemins de fer Français (SNCF).
Travelling from Nantes to Lyon: related information
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