Travel Information
Compare train, bus, and flight for Nantes to Lyon
Omio recommends booking the train as it is the most popular option from Nantes to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from €22. For those with little time consider booking a flight which can get you there in 1h 18m. The ticket price range depends on the travel mode: a bus costs an average of €22, and a flight costs an average of €64.
Distance: 320 miles (516 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
€80 Average price | €154 Average price | €48 Average price Cheapest |
5h 33m Average total duration 5h 3m Onboard + 30m Additional time* | 4h 18m Average total duration Fastest 1h 18m Onboard + 3h 0m Additional time* | 9h 45m Average total duration 9h 15m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Travel optionsfrom Nantes to Lyon
How to get from Nantes to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Nantes to Lyon is by taking a bus because it’s the best combination of price and speed.
FlixBusCheapest
FlixBusFastest
AF6145Other options
5320
4406
4404
72404
FlixBus · FlixBus
FlixBus · FlixBus
U24328
U24713
U24715Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jan 29
Jan 30
Jan 31
Feb 01
Feb 02
Feb 03
Feb 04
Feb 05
Feb 06
Feb 07
Feb 08
Feb 09
Feb 10
Feb 11
Feb 12
Feb 13
Feb 14
Feb 15
Feb 16
Feb 17
Feb 18
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Nantes to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Nantes to Lyon.

This is compared to other travel options from Nantes to Lyon:
A bus is $17 (€13) less than a train for this route with tickets for a train from Nantes to Lyon costing on average $45 (€35).
A bus is $54 (€42) less than a flight for this route with tickets for a flight from Nantes to Lyon costing on average $81 (€64).
Other travel options to Lyon take longer:
Train takes on average 4h 26m.
Bus takes on average 9h 10m.
- Around 11 trains per day.
- Around 9 flights per day.
- Around 9 buses per day.
However, we recommend checking specific travel dates for your route between Nantes and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Nantes Atlantique Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Nantes station and arrive in Lyon Part Dieu.
- Buses mostly depart from Nantes, Route de Paris and arrive in Lyon, Perrache Bus Station.
- Travel with easyJet, Volotea, Air France to go to Lyon by flight.
- Travel with SNCF Intercités, TGV INOUI, TGV, SNCF to go to Lyon by train.
- Travel with BlaBlaCar Bus, FlixBus, BlaBlaCar to go to Lyon by bus.
- 2 direct flights per day with easyJet, Volotea.
- 4 direct trains per day with SNCF Intercités, TGV INOUI, SNCF.
- 4 direct buses per day with BlaBlaCar Bus, FlixBus, BlaBlaCar.
Travelling from Nantes to Lyon: related information
Here are some other resources that might have the information you need
