Travel Information
Compare train, bus, and flight for Nantes to Lyon
Omio recommends booking the train as it is the most popular option from Nantes to Lyon among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $52 For those with little time, consider booking a flight, which has an average total journey time of 3h 21m. Average ticket prices depend on the travel mode: a bus costs an average of $52, while a flight costs an average of $206.
Distance: 320 miles (516 km)
Compare train with
Most popular Train | Flight | Bus | Driving |
|---|---|---|---|
$92 Average price | $206 Average price | $52 Average price Cheapest | $223 Average price (fuel + tolls) |
7h 39m Average total duration 7h 9m Onboard + 30m Additional time* | 3h 21m Average total duration Fastest 1h 21m Onboard + 2h 0m Additional time* | 8h 22m Average total duration 7h 52m Onboard + 30m Additional time* | 6h 34m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Nantes to Lyon:
A bus is $40 (€32) less than a train for this route with tickets for a train from Nantes to Lyon costing on average $92 (€74).
A bus is $154 (€125) less than a flight for this route with tickets for a flight from Nantes to Lyon costing on average $206 (€167).
Other travel options to Lyon take longer:
Train takes on average 7h 39m.
Bus takes on average 8h 22m.
Tickets start at around $92 (€74) compared to roughly $223 (€180) in fuel and tolls — a saving of about $131 (€106). The journey takes 7h 9m versus 6h 34m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Nantes to Lyon
How to get from Nantes to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Nantes to Lyon is by taking a bus because it’s the best combination of price and speed.
7240411:35 PM9h10Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes8:45 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$681One-way0 transfers
Cheapest
7240411:35 PM9h10Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes8:45 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$681One-way0 transfers
Fastest
U243309:45 PM1h10Nantes Atlantique Airport10:55 PMLyon Saint Exupery Airport$1231One-way0 transfers
Other options
53004:50 AM4h40Nantes station9:30 AMLyon Part Dieu$771One-way0 transfers
44026:26 AM6h38Nantes station1:04 PMLyon Part Dieu$891One-way0 transfers
8804 · 66097:04 AM4h52Nantes station11:56 AMLyon Part Dieu$1411One-way1 transfer
FlixBus8:35 PM10h15Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes6:50 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$791One-way0 transfers
FlixBus · FlixBus12:20 AM12h35Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes12:55 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1021One-way1 transfer
88094 · 5010711:55 AM12h25Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes12:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$1051One-way1 transfer
U243289:00 AM1h15Nantes Atlantique Airport10:15 AMLyon Saint Exupery Airport$1201One-way0 transfers
V728186:50 PM1h10Nantes Atlantique Airport8:00 PMLyon Saint Exupery Airport$1581One-way0 transfers
AF61452:20 PM1h10Nantes Atlantique Airport3:30 PMLyon Saint Exupery Airport$1821One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Nantes to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Nantes to Lyon.

This is compared to other travel options from Nantes to Lyon:
A bus is $40 (€32) less than a train for this route with tickets for a train from Nantes to Lyon costing on average $92 (€74).
A bus is $154 (€125) less than a flight for this route with tickets for a flight from Nantes to Lyon costing on average $206 (€167).
Other travel options to Lyon take longer:
Train takes on average 7h 39m.
Bus takes on average 8h 22m.
- Around 11 flights per day.
- Around 11 trains per day.
- Around 11 buses per day.
However, we recommend checking specific travel dates for your route between Nantes and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Nantes Atlantique Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Nantes station and arrive in Lyon Part Dieu.
- Buses mostly depart from Nantes, Route de Paris and arrive in Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
- Travel with SNCF | Intercités, SNCF | TGV INOUI, TGV, Société Nationale des Chemins de fer Français (SNCF) to go to Lyon by train.
- Travel with FlixBus, BlaBlaCar Bus, BlaBlaCar, Naolib to go to Lyon by bus.
- Travel with easyJet, Volotea, Air France to go to Lyon by flight.
- 4 direct trains per day with SNCF | TGV INOUI, Société Nationale des Chemins de fer Français (SNCF).
- 4 direct buses per day with FlixBus, BlaBlaCar Bus, BlaBlaCar.
- 2 direct flights per day with easyJet, Volotea, Air France.
Travelling from Nantes to Lyon: related information
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