- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.










Cheapest price
$164
Average price
$217
Fastest journey
20h 5m
Average duration
23h 39m
Buses per day
15
Distance
409 km
Omio recommends booking the flight as it is the most popular option from Nantes to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $72. For those with little time consider booking a flight which can get you there in 2h 50m. The ticket price range depends on the travel mode: a bus costs an average of $72, and a flight costs an average of $58.
Distance: 753 miles (1213 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$115 Average price Cheapest | $184 Average price | $383 Average price (fuel + tolls) |
20h 31m Average total duration 20h 1m Onboard + 30m Additional time* | 5h 50m Average total duration Fastest 2h 50m Onboard + 3h 0m Additional time* | 14h 36m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Nantes to Prague:
A bus is $69 (€57) less than a flight for this route with tickets for a flight from Nantes to Prague costing on average $184 (€151).
Other travel options to Prague take longer:
Bus takes on average 20h 1m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:20AM | Arrival Time 11:10PM | Duration 22h50 | Departure days Wed, Fri, Sun | Cheapest price $181 |
Operator FlixBus | Departure Time 12:30AM | Arrival Time 10:55PM | Duration 22h25 | Departure days Mon, Tue, Thu, Sat | Cheapest price $147 |
Operator FlixBus | Departure Time 09:45AM | Arrival Time 10:35AM | Duration 24h50 | Departure days Everyday | Cheapest price $100 |
Operator FlixBus | Departure Time 10:45AM | Arrival Time 10:35AM | Duration 23h50 | Departure days Mon, Tue | Cheapest price $101 |
Operator BlaBlaCar Bus | Departure Time 01:40PM | Arrival Time 09:45AM | Duration 20h05 | Departure days Mon, Fri | Cheapest price $164 |
Operator FlixBus | Departure Time 01:40PM | Arrival Time 10:05AM | Duration 20h25 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $112 |
Operator FlixBus | Departure Time 04:30PM | Arrival Time 05:35PM | Duration 25h05 | Departure days Everyday | Cheapest price $103 |
Operator FlixBus | Departure Time 08:40PM | Arrival Time 10:55PM | Duration 26h15 | Departure days Sat | Cheapest price $250 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 11:10PM | Duration 25h45 | Departure days Everyday | Cheapest price $101 |
The table below shows live departures for Nantes to Prague buses for today, Friday, July 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 9:45 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 25h45 | 11:30 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 9:45 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 25h45 | 11:30 AM Praha, Zličín | 3 transfers | |
FlixBus · FlixBus · FlixBus | 9:45 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 24h50 | 10:35 AM Prague, Central Train Station | 2 transfers | |
50816 · 30512 | 1:40 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 20h05 | 9:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 1:40 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 20h55 | 10:35 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:40 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 21h40 | 11:20 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 1:40 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 20h25 | 10:05 AM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:40 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 27h05 | 4:45 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:30 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 25h05 | 5:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:30 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 23h40 | 4:10 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus | 4:30 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 20h35 | 1:05 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 4:30 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 20h15 | 12:45 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:25 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 25h45 | 11:10 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:25 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 25h30 | 10:55 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 9:25 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 27h20 | 12:45 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 12:30 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 22h25 | 10:55 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 12:30 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 22h40 | 11:10 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 12:30 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 24h15 | 12:45 AM Prague, Central Train Station | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Nantes to Prague run on average 14 times per day, taking around 20h 1m. Cheap bus tickets for this journey start at $72 (€59) but you can travel from only $58 (€48) by flight.
The earliest bus runs at 00:20, the last at 23:55. The fastest bus covers the 753 miles (1213 km) distance in 20h 5m.
Distance 753 miles (1213 km) |
Average bus duration 20h 1m |
Cheapest ticket price $72 (€59) |
Buses per day 14 |
Fastest bus 20h 5m |
First bus 12:20 AM |
Last bus 11:55 PM |
Cheapest Month May |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Tue |
Least Busy Day Sat |
Best time to book 21 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Find answers to the most common questions about traveling from Nantes to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Nantes to Prague buses use the Nantes, Route de Paris to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Nantes and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Nantes, Route de Paris is 4 km from Nantes city centre. Public transport options include:
Nantes, Route de Paris has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Fast Food Express (in the station).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Nantes, Route de Paris.
Available at Nantes, Route de Paris: Parking, Taxis, WC.
Accessibility facilities are available at Nantes, Route de Paris: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Here are some other resources that might have the information you need