- Must visit
Vatican Museums
One of the world's great museum complexes, home to vast papal collections and the Sistine Chapel. A priority visit for art, history, and Renaissance masterpieces.
We are not able to find a bus between these two places.
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Omio recommends booking the bus as it is the most popular option from Milordo to Rome among Omio's users. If you are prioritising price take the train with prices starting from $30. For those with little time consider booking a bus which can get you there in 4h 59m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a train costs an average of $30, and a bus costs an average of $22.
Distance: 219 miles (353 km)
Most popular Bus | Train | Driving |
|---|---|---|
$36 Average price | $32 Average price Cheapest | $79 Average price (fuel + tolls) |
5h 29m Average total duration Fastest 4h 59m Onboard + 30m Additional time* | 7h 50m Average total duration 7h 20m Onboard + 30m Additional time* | 4h 5m Average total duration (door-to-door) |
0.4 - 0.9kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Milordo to Rome:
A train is $4 (€3) less than a bus for this route with tickets for a bus from Milordo to Rome costing on average $36 (€30).
Other travel options to Rome take longer:
Train takes on average 7h 20m.
Tickets start at around $36 (€30) compared to roughly $79 (€65) in fuel and tolls — a saving of about $43 (€35). The journey takes 4h 59m versus 4h 5m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Marino Autolinee, Itabus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Itabus | Departure Time 12:26AM | Arrival Time 05:45AM | Duration 5h19 | Departure days Fri | Cheapest price $23 |
Operator FlixBus | Departure Time 12:30AM | Arrival Time 05:15AM | Duration 4h45 | Departure days Sun | Cheapest price $23 |
Operator Marino Autolinee | Departure Time 06:45AM | Arrival Time 11:35AM | Duration 4h50 | Departure days Wed | Cheapest price $34 |
Operator FlixBus | Departure Time 01:31PM | Arrival Time 06:10PM | Duration 4h39 | Departure days Tue, Thu | Cheapest price $34 |
The table below shows live departures for Milordo to Rome buses for tomorrow, Friday, July 10. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:26 AM Milordo | 5h19 | 5:45 AM Rome | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Milordo to Rome run on average 11 times per day, taking around 4h 59m. Cheap bus tickets for this journey start at $22 (€18) if you book in advance.
There are 5 buses per day. The earliest bus runs at 00:15, the last at 23:56. The fastest bus covers the 219 miles (353 km) distance in 4h 39m.
Distance 219 miles (353 km) |
Average bus duration 4h 59m |
Cheapest ticket price $22 (€18) |
Buses per day 11 |
Direct buses 5 |
Fastest bus 4h 39m |
First bus 12:15 AM |
Last bus 11:56 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 4 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
One of the world's great museum complexes, home to vast papal collections and the Sistine Chapel. A priority visit for art, history, and Renaissance masterpieces.
A superb villa museum with Bernini sculptures and major paintings by Caravaggio, Raphael, and Titian. Timed entry is essential due to limited capacity.
The city's historic civic museums on Capitoline Hill, known for classical sculpture, ancient Roman art, and excellent views over the Forum.
A lively Baroque square with monumental fountains, elegant facades, and one of the most recognizable urban spaces in Rome.
A famous stairway and gathering point linking Piazza di Spagna with Trinita dei Monti, especially popular for photos and central city strolls.
A beloved neighborhood of narrow lanes, ivy-covered buildings, and lively Roman atmosphere, ideal for wandering day or night.
A classic Roman pasta with pecorino Romano, black pepper, and pasta water. It is one of the city’s most iconic dishes for its simplicity and bold flavor.
Traditional Roman pasta made with guanciale, egg yolk, pecorino Romano, and black pepper. It is a defining dish of Rome and is famously made without cream.
A beloved pasta sauce of tomato, guanciale, pecorino Romano, and chili. Though linked to Amatrice, it is deeply rooted in Roman trattoria cooking.
Rome’s best-known luxury fine-dining restaurant, famous for panoramic views, elegant service, and sophisticated Italian cuisine.
A historic restaurant near the Pantheon serving refined Roman classics with strong local identity. Well known for seasonal specialties and pasta.
A celebrated central Rome dining room known for Roman pasta, cured meats, and an exceptional wine list. Lively, polished, and very popular.
Moderate for Western Europe. Sights and central hotels cost more, but food, coffee, and transit can be good value.
Service is often included or modest. Locals may round up or leave EUR 1-2 at cafes; 5-10% is appreciated at restaurants for good service, not obligatory. Round up taxis.
Official public transport app
Rome, Via Marsala / Viale Enrico De Nicola, Rome -> Rome Termini
Find answers to the most common questions about traveling from Milordo to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Milordo to Rome buses use the Lauria, A2 (Sergio Petroli) to Roma, Autostazione Tiburtina station pair, with some services arriving at Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine". Use this guide to compare Milordo and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need