Milan to Palermo bus with FlixBus

Wed, Apr 22
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Autoservizi Salemi
Itabus
Salemi
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Milan - PalermoCompare FlixBus, Autoservizi Salemi, Itabus

meinfernbus_flixbus
$42
21h 55m
6 a day
Power plugs
Wifi
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
asal
$100
21h 0m
2 a day
Power plugs
Wifi
Two pieces of luggage: one large suitcase for the hold and one smaller backpack for on-board.
itab
$36
22h 40m
2 a day
Power plugs
Wifi
One carry-on bag up to 10kg and one checked bag up to 20kg.

The cheapest and fastest buses from Milan to Palermo

Showing times and prices for Apr 22

Cheapest price

$101

Average price

$133

Fastest journey

21 h

Average duration

22 h 14 m

Buses per day

8

Distance

887 km

Cheap tickets

The best way to find a cheap bus ticket from Milan to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Milan to Palermo will cost around $133 if you buy it on the day, but the cheapest tickets can be found for only $101.

Fast buses

Of the 8 buses that leave Milan for Palermo on Wed, Apr 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Wed, Apr 22 the direct buses cover the 887 km distance in an average of 22 h 14 m but if you time it right, some buses will get you there in just 21 h .

On Wed, Apr 22 the slowest buses will take 1 d and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Salemi700 · S201
    10:00 AM21h45
    Milano, Autostazione Lampugnano
    7:45 AMPalermo, Via Tommaso Fazello (Terminal Bus)
    $1011One-way
    1 transfer
  • Salemi700 · S201
    10:45 AM21h00
    Milano, San Donato M3
    7:45 AMPalermo, Via Tommaso Fazello (Terminal Bus)
    $1011One-way
    1 transfer
  • FlixBusFlixBus · FlixBus
    3:15 PM24h00
    Milano, Autostazione Lampugnano
    3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)
    $1301One-way
    1 transfer
  • FlixBusFlixBus · FlixBus
    12:45 PM26h30
    Milano, San Donato - Settore B (Viale Giuseppe Impastato)
    3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)
    $1301One-way
    1 transfer
  • FlixBusFlixBus
    1:05 PM21h55
    Milano, Autostazione Lampugnano
    11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)
    $1381One-way
    0 transfers

Travel Information

Compare train, bus, flight, and ferry for Milan to Palermo

Omio recommends booking the flight as it is the most popular option from Milan to Palermo among Omio's users. If you are prioritising price take the ferry with prices starting from $83. For those with little time consider booking a flight which can get you there in 1h 52m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 0.8kg. The ticket price range depends on the travel mode: a ferry costs an average of $83, and a flight costs an average of $22.

Distance: 551 miles (887 km)

Compare bus with

Bus
Most popular
Flight
Train
Ferry

$111

Average price

$160

Average price

$149

Average price

$91

Average price

Cheapest

20h 38m

Average total duration

20h 8m

Onboard

+

30m

Additional time*

4h 52m

Average total duration

Fastest

1h 52m

Onboard

+

3h 0m

Additional time*

16h 40m

Average total duration

16h 10m

Onboard

+

30m

Additional time*

21h 4m

Average total duration

20h 4m

Onboard

+

1h 0m

Additional time*

0.9 - 2.2kg

CO2 emissions

2.7 - 5.3kg

CO2 emissions

0.3 - 0.8kg

CO2 emissions

Lowest

-

CO2 emissions

FlixBus

Most popular bus company

Malta Air

Most popular airline

Intercity Notte

Most popular train company

Gnv

Most popular ferry company

Direct Options

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Milan to Palermo Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
09:40AM
Arrival Time
11:00AM
Duration
25h20
Departure days
Mon
Cheapest price
$111
Operator
Salemi
Departure Time
10:00AM
Arrival Time
07:45AM
Duration
21h45
Departure days
Mon, Wed, Fri
Cheapest price
$100
Operator
FlixBus
Departure Time
10:20AM
Arrival Time
03:15PM
Duration
28h55
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
$118
Operator
Salemi
Departure Time
10:45AM
Arrival Time
07:45AM
Duration
21h00
Departure days
Mon, Wed, Fri
Cheapest price
$100
Operator
FlixBus
Departure Time
12:30PM
Arrival Time
11:00AM
Duration
22h30
Departure days
Wed, Thu, Fri, Sat, Sun
Cheapest price
$106
Operator
FlixBus
Departure Time
12:45PM
Arrival Time
03:15PM
Duration
26h30
Departure days
Wed
Cheapest price
$130
Operator
FlixBus
Departure Time
01:05PM
Arrival Time
11:00AM
Duration
21h55
Departure days
Mon, Wed, Thu, Fri, Sat, Sun
Cheapest price
$111
Operator
FlixBus
Departure Time
02:25PM
Arrival Time
03:15PM
Duration
24h50
Departure days
Thu
Cheapest price
$143
Operator
FlixBus
Departure Time
02:45PM
Arrival Time
03:15PM
Duration
24h30
Departure days
Mon, Fri, Sat, Sun
Cheapest price
$103
Operator
FlixBus
Departure Time
03:15PM
Arrival Time
03:15PM
Duration
24h00
Departure days
Mon, Wed, Thu, Fri, Sat, Sun
Cheapest price
$103
Operator
FlixBus
Departure Time
05:45PM
Arrival Time
07:20PM
Duration
25h35
Departure days
Everyday
Cheapest price
$100
Operator
FlixBus
Departure Time
06:30PM
Arrival Time
07:20PM
Duration
24h50
Departure days
Everyday
Cheapest price
$99

Live departures

Milan to Palermo bus times

The table below shows live departures for Milan to Palermo buses for today, Tuesday, April 21. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbusFlixBus · FlixBus5:45 PM Milano, Autostazione Lampugnano
25h35
7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus)1 transfer
meinfernbus_flixbusFlixBus · FlixBus6:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato)
24h50
7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus)1 transfer
Wednesday, April 22
salemi700 · S20110:00 AM Milano, Autostazione Lampugnano
21h45
7:45 AM Palermo, Via Tommaso Fazello (Terminal Bus)1 transfer
salemi700 · S20110:45 AM Milano, San Donato M3
21h00
7:45 AM Palermo, Via Tommaso Fazello (Terminal Bus)1 transfer
meinfernbus_flixbusFlixBus · FlixBus12:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato)
22h30
11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus)1 transfer
meinfernbus_flixbusFlixBus · FlixBus12:45 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato)
26h30
3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus)1 transfer
meinfernbus_flixbusFlixBus1:05 PM Milano, Autostazione Lampugnano
21h55
11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus)0 transfersDirect
meinfernbus_flixbusFlixBus · FlixBus3:15 PM Milano, Autostazione Lampugnano
24h00
3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus)1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Milan to Palermo by train, bus, flight, or ferry

Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Milan to Palermo buses with Omio?

FlixBus as well as Autoservizi Salemi, Itabus, Salemi, Infobus and more offer buses services from Milan to Palermo.
Omio is an official ticket reseller for all your travel options from Milan to Palermo.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Autoservizi Salemi, Itabus, Salemi or Infobus to find the best option for your trip from Milan to Palermo.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Milan to Palermo.

Why book with Omio over Wanderu, Trainline or Checkmybus?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of Autoservizi Salemi, Itabus, Salemi or Infobus to find the best option for your trip from Milan to Palermo.
  • Multiple modes of transport: Omio allows you to compare travel options including train, bus, flight and ferry to find the ideal travel option from Milan to Palermo.

Journey information

Overview: Bus from Milan to Palermo

ItalyItaly
ItalyItaly
Icon of bus

Buses from Milan to Palermo run on average 6 times per day, taking around 20h 8m. Cheap bus tickets for this journey start at $42 (€33) but you can travel from only $22 (€17) by flight.

There are 1 buses per day. The earliest bus runs at 00:52, the last at 22:45. The fastest bus covers the 551 miles (887 km) distance in 21h 55m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $22 (€17)
Distance
551 miles (887 km)
Average bus duration
20h 8m
Cheapest ticket price
$42 (€33)
Buses per day
6
Direct buses
1
Fastest bus
21h 55m
First bus
12:52 AM
Last bus
10:45 PM
Cheapest Month
May
Cheapest Day
Sat
High Season
Jul - Sep
Low Season
Jan - Mar
Busiest Day
Wed
Least Busy Day
Sat
Best time to book
35 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $22 (€17)

Buses from Milan to Palermo

Bus trips to Milan and Palermo have a total duration of about 20 hours, including the passage over the Strait of Messina. Every day there are generally four journeys: two direct journeys and two routes with change, with a departure in the middle of the day and three evening journeys. The vehicles depart from the Bus Station of Lampugnano or the San Donato Bus Station, while the arrival station in Palermo is located in Piazza Cairoli.

Which bus lines operate the Milan-Palermo route?

The company that makes the direct trip is Bus Center, provides two trips a day and provides between services on board toilets and electrical outlets. The connection with gearbox is offered instead by the line Baltour.

How long does the bus journey from Milan to Palermo take?

The direct trip to Milan Palermo operated by Bus Center bus lines lasts from 19 to 22 hours. The change connection proposed by Baltour provides departures from the Bus Station of Lampugnano, with a journey time between 17 hours and 45 minutes and 18 hours and 30 minutes.

How many buses are there Milan-Palermo?

Two direct rides are scheduled each day, departing around 13:45 and 20:45. Coach services that make trips with change leave Milan in the evening with arrival in the next afternoon. A total of at least 25 connections are guaranteed each week.

Where do the buses Milan-Palermo depart from and where do they arrive?

Milan Palermo buses leave from Lampugnano Bus Station, which can be reached by metro, or from Piazzale San Donato Bus Station, which is connected to the city centre by the M3 underground. The terminus is in Palermo in Piazza Cairoli, connected to the rest of the city by several bus lines.

FAQs: Bus from Milan to Palermo

Find answers to the most common questions about traveling from Milan to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Milan to Palermo can start from as little as $42 (€33) when you book in advance. The average bus ticket price for Milan to Palermo is $111 (€89) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Milan to Palermo is 21h 55m to travel the 551 miles (887 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Milan to Palermo leaves at 12:52 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Milan to Palermo leaves at 10:45 PM.
Yes, there are 1 direct buses a day from Milan to Palermo with FlixBus, Itabus, BlaBlaCar, Infobus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Milan to Palermo, you can count on FlixBus, Autoservizi Salemi, Itabus, Salemi, BlaBlaCar, Infobus for the best way to get you to Palermo. You can also check all possible bus companies who offer a service between Milan and Palermo and compare the amenities they offer before buying a bus ticket.
When departing from Milan , you have various bus station options to start your journey from including Milano, Autostazione Lampugnano, Milano, San Donato - Settore B (Viale Giuseppe Impastato), Milano, Milan Linate Airport, Milano, San Donato M3, Assago, Viale Milanofiori (Assago M2), Sesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria), Cormano, A4 (Cusano Milanino East), Cormano, A4 (Cusano Milanino West), Roma, Autostazione Tiburtina . When arriving in Palermo , you can end your journey in bus stations like Palermo, Via Tommaso Fazello (Terminal Bus), Termini Imerese, Gatto Carburanti .Passengers board the bus most frequently from Milano, Autostazione Lampugnano, which is located around 5 away from the city centre, and they get off the bus at Palermo, Via Tommaso Fazello (Terminal Bus), located 1 away from the city centre.
A trip to Palermo from Milan is worth doing but not as a day trip with a journey time of 21h 55m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Milan to Palermo is May.
It's helpful to compare your options as there are 4 ways to travel between Milan and Palermo including taking a train, bus, flight, and ferry.
Yes, the following accessibility options are available when taking the bus from Milan to Palermo:
  • Infobus
    • Assistance
    • Priority seating
    • Transport for wheelchairs and mobility aids.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
  • Itabus
    • Assistance
    • Dedicated seating areas
    • Accessible restrooms.
Yes, there are bathrooms on board the bus from Milan to Palermo for bus company FlixBus, Autoservizi Salemi, Itabus, Infobus.
Some of the most interesting sights to explore in Palermo are:
  • Palermo Cathedral, a stunning architectural blend of Norman, Moorish, and Baroque styles
  • Teatro Massimo, Italy's largest opera house known for its grand performances and impressive acoustics
  • Palazzo dei Normanni, a historic palace featuring the exquisite Palatine Chapel with its Byzantine mosaics
  • Quattro Canti, a Baroque square at the intersection of Palermo's two main streets, known for its symmetrical fountains and statues
  • Orto Botanico di Palermo, a lush botanical garden showcasing diverse plant species.
The best things to do in Palermo include:
  • Capuchin Catacombs, an eerie yet fascinating underground cemetery with mummified remains
  • Ballarò Market, a bustling street market offering a taste of local Sicilian produce and culture
  • Explore the vibrant street art in the Vucciria district
  • Take a cooking class to learn how to make traditional Sicilian dishes
  • Enjoy a leisurely stroll along the picturesque Foro Italico promenade.
Whether you can cancel your bus ticket from Milan to Palermo depends on the bus companies:
  • Autoservizi Salemi
    • The cancellation policy can vary by ticket class, individual trips, or promotions, so it's best to check the terms during booking.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
  • Itabus
    • You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Yes, bikes are allowed on board the bus with bus company FlixBus, Itabus, Infobus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Milan to Palermo.
Yes, the following luggage options are included when booking a bus ticket from Milan to Palermo:
  • Autoservizi Salemi
    • Two pieces of luggage: one large suitcase for the hold and one smaller backpack for on-board.
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
  • Itabus
    • One carry-on bag up to 10kg and one checked bag up to 20kg.
Yes, the following additional luggage options are available when booking a bus ticket from Milan to Palermo:
  • Infobus
    • 10€ per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
  • Itabus
    • 5€ per additional bag.
Yes, you can bring your pet on the bus from Milan to Palermo. The following conditions apply:
  • Infobus
    • Small pets allowed in carriers
    • larger pets may require a separate ticket.
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
  • Itabus
    • Small pets allowed in carriers
    • larger pets must be leashed and muzzled.
You can reserve your seat on the bus from Milan to Palermo with the following bus company: FlixBus, Itabus, Infobus
Yes, there are USB plugs on board the bus from Milan to Palermo with the following bus company: FlixBus, Autoservizi Salemi, Itabus, Infobus.
Yes, there is Wifi on board the bus from Milan to Palermo with the following bus company: FlixBus, Autoservizi Salemi, Itabus, Infobus.
Since both Milan and Palermo are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Milan to Palermo among Omio's users.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Palermo, travelers should be cautious of petty theft, especially pickpocketing in crowded areas like markets and public transport. Scams include overcharging by taxi drivers and vendors, as well as unofficial guides offering overpriced tours. It's advisable to use authorized services and stay vigilant in busy tourist spots.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Milan to Palermo

Milan
Palermo
Milano, Autostazione LampugnanoWifiParkingDiningATMTaxisAccessibilityWCTicket Office
Amenities at bus station
WifiWifi
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
Ticket OfficeTicket Office
information
ticketOfficeHours
Ticket Office Hours
  • 06:00-23:00
ticketOfficeHours
Distance to city center
5 km
carConnection
Car connection
Via Giulio Natta
Wifi
Wifi
  • Free Wi-Fi
Dining
Dining
  • Cafeteria Lampugnano (in the station)
  • Trattoria Milano (0.5 km)
  • Pizza Express (0.7 km).
Taxis
Taxis
  • Available outside the station.
Accessibility
Accessibility
  • Elevators, ramps
WC
WC
  • Available in the station.
Public transit options for Milano, Autostazione Lampugnano
  • Metro: M1 Bus: 68, 78, 80
Milano, San Donato - Settore B (Viale Giuseppe Impastato)WifiParkingDiningATMTaxisAccessibilityWCTicket Office
Amenities at bus station
WifiWifi
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
Ticket OfficeTicket Office
information
ticketOfficeHours
Ticket Office Hours
  • 06:00-22:00
ticketOfficeHours
Distance to city center
6 km
carConnection
Car connection
Viale Giuseppe Impastato
Wifi
Wifi
  • Free Wi-Fi
Dining
Dining
  • Cafeteria Italiana (in the station)
  • Fast Food Express (in the station)
  • Trattoria Milano (0.5 km).
Taxis
Taxis
  • Available outside the station.
Accessibility
Accessibility
  • Elevators, ramps
WC
WC
  • Available in the station.
Public transit options for Milano, San Donato - Settore B (Viale Giuseppe Impastato)
  • Bus: 121, 132 Metro: M3
Milano, Aeroporto di Milano Linate
information

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