- Must visit
Museo Archeologico Provinciale Francesco Ribezzo
Main civic museum with archaeology, sculptures, and local history collections that provide the best introduction to Brindisi and its territory.
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The cheapest and fastest buses from Siena to Brindisi
Showing times, prices and bookable tickets for Sep 18
Cheapest price on Sep 18
€30
Average ticket price on Sep 18
€55
Fastest journey on Sep 18
11 h
Average journey duration on Sep 18
11 h 15 m
Buses on Sep 18
14
Distance
622 km
Cheap tickets
The best way to find a cheap bus ticket from Siena to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Siena to Brindisi will cost around €55 if you buy it on the day, but the cheapest tickets can be found for only €30.
Fast buses
On Fri, Sep 18, we found 14 buses from Siena to Brindisi, including 3 direct services.
On Fri, Sep 18 the direct buses cover the 622 km distance in an average of 11 h 15 m but if you time it right, some buses will get you there in just 11 h .
On Fri, Sep 18 the slowest buses will take 11 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
11219:25 AM11h00Siena, Stazione FS (Piazzale Carlo Rosselli)8:25 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€301One-way0 transfers- 2401 · 11075:55 PM12h30Siena, Stazione FS (Piazzale Carlo Rosselli)6:25 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€441One-way1 transfer
- 2125 · 11074:25 PM14h00Siena, Stazione FS (Piazzale Carlo Rosselli)6:25 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€501One-way1 transfer
FlixBus · FlixBus7:45 PM11h30Siena, Stazione FS (Piazzale Carlo Rosselli)7:15 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€501One-way1 transfer
1088:30 PM11h55Siena, Stazione FS (Piazzale Carlo Rosselli)8:25 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€521One-way0 transfers
- 11219:25 AM11h00Siena, Stazione FS (Piazzale Carlo Rosselli)8:25 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€301One-way0 transfers
- 20711:05 AM11h05Siena, Stazione FS (Piazzale Carlo Rosselli)10:10 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€541One-way0 transfers
- FlixBus · FlixBus7:10 AM11h15Siena, Siena/Viale Pietro Toselli6:25 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€561One-way1 transfer
- FlixBus · FlixBus7:00 AM11h25Siena, Stazione FS (Piazzale Carlo Rosselli)6:25 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€541One-way1 transfer
- FlixBus · FlixBus7:45 PM11h30Siena, Stazione FS (Piazzale Carlo Rosselli)7:15 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€501One-way1 transfer
Travel Information
Compare bus, train, and flight for Siena to Brindisi
Omio recommends booking the bus as it is the most popular option from Siena to Brindisi among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €79 For those with little time, consider booking a flight, which has an average total journey time of 3h 25m. Average ticket prices depend on the travel mode: a bus costs an average of €79, while a flight costs an average of €189.
Distance: 386 miles (622 km)
Compare bus with
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
€79 Average price Cheapest | €189 Average price | €112 Average price | €60 Average price (fuel + tolls) |
11h 32m Average total duration 11h 2m Onboard + 30m Additional time* | 3h 25m Average total duration Fastest 1h 25m Onboard + 2h 0m Additional time* | 10h 16m Average total duration 9h 46m Onboard + 30m Additional time* | 7h 22m Average total duration (door-to-door) |
Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Siena to Brindisi is a bus with an average price of €79.
This is compared to other travel options from Siena to Brindisi:
A bus is €33 less than a train for this route with tickets for a train from Siena to Brindisi costing on average €112.
A bus is €110 less than a flight for this route with tickets for a flight from Siena to Brindisi costing on average €189.
The fastest way to travel from Siena to Brindisi is by flight with an average journey time of 1h 25m.
Other travel options to Brindisi take longer:
Train takes on average 9h 46m.
Bus takes on average 11h 2m.
It's helpful to compare your options as there are 3 ways to travel between Siena and Brindisi including taking a bus, train, and flight.
We recommend using the bus as it is the most popular way to get from Siena to Brindisi among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around €79 compared to roughly €60 in fuel and tolls — a saving of about €-19.44. The journey takes 11h 2m versus 7h 22m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Siena to Brindisi Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:45AM | Arrival Time 04:40PM | Duration 15h55 | Departure days Fri, Sat | Cheapest price €67 |
Operator FlixBus | Departure Time 03:35AM | Arrival Time 04:25PM | Duration 12h50 | Departure days Mon | Cheapest price €63 |
Operator FlixBus | Departure Time 06:50AM | Arrival Time 06:25PM | Duration 11h35 | Departure days Wed, Thu, Fri, Sat | Cheapest price €40 |
Operator FlixBus | Departure Time 07:00AM | Arrival Time 06:25PM | Duration 11h25 | Departure days Wed, Thu, Fri, Sat | Cheapest price €40 |
Operator FlixBus | Departure Time 07:10AM | Arrival Time 06:25PM | Duration 11h15 | Departure days Wed, Thu, Fri, Sat | Cheapest price €40 |
Operator Itabus | Departure Time 07:25AM | Arrival Time 06:25PM | Duration 11h00 | Departure days Mon, Tue, Sun | Cheapest price €30 |
Operator Itabus | Departure Time 08:25AM | Arrival Time 07:25PM | Duration 11h00 | Departure days Mon, Sun | Cheapest price €35 |
Operator FlixBus | Departure Time 08:45AM | Arrival Time 10:25PM | Duration 13h40 | Departure days Fri | Cheapest price €60 |
Operator Itabus | Departure Time 09:25AM | Arrival Time 08:25PM | Duration 11h00 | Departure days Fri | Cheapest price €30 |
Operator FlixBus | Departure Time 10:35AM | Arrival Time 10:25PM | Duration 11h50 | Departure days Thu, Sat | Cheapest price €37 |
Operator FlixBus | Departure Time 10:45AM | Arrival Time 10:25PM | Duration 11h40 | Departure days Thu, Sat | Cheapest price €37 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 10:25PM | Duration 11h30 | Departure days Thu, Sat | Cheapest price €37 |
Operator Marino Autolinee | Departure Time 11:05AM | Arrival Time 10:10PM | Duration 11h05 | Departure days Wed, Thu, Fri, Sat | Cheapest price €44 |
Operator FlixBus | Departure Time 02:51PM | Arrival Time 06:10AM | Duration 15h19 | Departure days Wed, Thu, Fri, Sat | Cheapest price €38 |
Operator Itabus | Departure Time 04:25PM | Arrival Time 06:25AM | Duration 14h00 | Departure days Wed, Fri | Cheapest price €22 |
Operator FlixBus | Departure Time 04:25PM | Arrival Time 04:10AM | Duration 11h45 | Departure days Tue | Cheapest price €65 |
Operator Itabus | Departure Time 05:55PM | Arrival Time 06:25AM | Duration 12h30 | Departure days Fri | Cheapest price €44 |
Operator FlixBus | Departure Time 06:25PM | Arrival Time 06:10AM | Duration 11h45 | Departure days Wed, Thu, Fri, Sat | Cheapest price €36 |
Operator Marino Autolinee | Departure Time 06:30PM | Arrival Time 06:25AM | Duration 11h55 | Departure days Sun | Cheapest price €58 |
Operator Marino Autolinee | Departure Time 07:30PM | Arrival Time 07:25AM | Duration 11h55 | Departure days Tue | Cheapest price €53 |
Operator FlixBus | Departure Time 07:45PM | Arrival Time 07:15AM | Duration 11h30 | Departure days Thu, Fri, Sat | Cheapest price €50 |
Operator Marino Autolinee | Departure Time 08:30PM | Arrival Time 08:25AM | Duration 11h55 | Departure days Wed, Thu, Fri, Sat | Cheapest price €45 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 12:25PM | Duration 15h00 | Departure days Tue | Cheapest price €35 |
Operator FlixBus | Departure Time 10:25PM | Arrival Time 01:55PM | Duration 15h30 | Departure days Wed, Thu, Fri, Sat | Cheapest price €32 |
Live departures
Siena to Brindisi bus times
The table below shows live departures for Siena to Brindisi buses for today, Thursday, September 17. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 6:50 AM Siena, P.za Gramsc | 11h35 | 6:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
| FlixBus · FlixBus | 7:00 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 11h25 | 6:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
| FlixBus · FlixBus | 7:10 AM Siena, Siena/Viale Pietro Toselli | 11h15 | 6:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 10:35 AM Siena, P.za Gramsc | 11h50 | 10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 10:45 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 11h40 | 10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 10:55 AM Siena, Siena/Viale Pietro Toselli | 11h30 | 10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
| 207 | 11:05 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 11h05 | 10:10 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
| FlixBus · FlixBus · FlixBus | 2:51 PM Siena, Siena/Viale Pietro Toselli | 15h19 | 6:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
| FlixBus · FlixBus | 6:25 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 11h45 | 6:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
| FlixBus · FlixBus | 7:45 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 11h30 | 7:15 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
| 108 | 8:30 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 11h55 | 8:25 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
| FlixBus · FlixBus · FlixBus | 10:25 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 15h30 | 1:55 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 10:25 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 15h30 | 1:55 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
| Friday, September 18 | |||||
| FlixBus · FlixBus · FlixBus | 12:45 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 15h55 | 4:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Siena to Brindisi by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Siena to Brindisi buses with Omio?
Marino Autolinee as well as Itabus or FlixBus offer buses services from Siena to Brindisi.
Omio is an official ticket reseller for all your travel options from Siena to Brindisi.
Why book with Omio vs Marino Autolinee?
- Compare with other providers: On Omio, you can not only buy tickets for Marino Autolinee, but also compare tickets for the likes of Itabus or FlixBus to find the best option for your trip from Siena to Brindisi.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Marino Autolinee with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Siena to Brindisi.
Why book with Omio over Checkmybus, Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus or FlixBus to find the best option for your trip from Siena to Brindisi.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Siena to Brindisi.
Journey information
Overview: Bus from Siena to Brindisi
ItalyItaly
Buses from Siena to Brindisi run on average 13 times per day, taking around 11h 2m. Cheap bus tickets for this journey start at €25 if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:05, the last at 23:39. The fastest bus covers the 386 miles (622 km) distance in 9h 59m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 386 miles (622 km) |
Average bus duration 11h 2m |
Cheapest ticket price €25 |
Buses per day 13 |
Direct buses 3 |
Fastest bus 9h 59m |
First bus 12:05 AM |
Last bus 11:39 PM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Sat |
Best time to book 5 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus, Itabus, Marino Autolinee from Siena to BrindisiYou can travel by bus between Siena to Brindisi with FlixBus, Itabus, Marino Autolinee for as low as €25. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
9h 59m
Cheapest FlixBus Price
€45
FlixBus frequency
11 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Itabus
About
Itabus is a leading bus company in Italy, providing reliable and comfortable transportation services to its customers. Itabus operates a fleet of modern buses, ranging from luxury coaches to standard buses, all equipped with air conditioning, comfortable seating, and onboard entertainment.
Luggage & cancellation policy
Average Itabus Duration
10h 35m
Cheapest Itabus Price
€25
Itabus frequency
2 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 20kg.
Additional luggage
5€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Dedicated seating areas; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.
Marino Autolinee
About
MarinoBus is an Italian bus company with more than 200 destinations and 6,000 connections across Italy and Europe. Originally focused on Basilicata and Apulia, its network has expanded to cover the rest of Italy as well as Switzerland, France, Germany, and Luxembourg. All MarinoBus coaches are equipped with spacious reclining seats, air conditioning, onboard restrooms, WiFi, minibars, and color TVs. For your next trip, you can book the standard ticket, which includes one piece of hand luggage and up to two checked bags per passenger
Luggage & cancellation policy
Average Marino Autolinee Duration
11h 5m
Cheapest Marino Autolinee Price
€49
Marino Autolinee frequency
2 a day
Luggage included
One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
10€ per additional bag up to 20 kg.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.
Complete guide to Brindisi
Things to do in Brindisi
Discover the best of Brindisi — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brindisi trip today.
- Recommended
Area Archeologica di San Pietro degli Schiavoni
Archaeological zone and small interpretive museum preserving a Roman domus with mosaics, ideal for understanding everyday life in ancient Brindisi.
- Recommended
Chiesa di San Giovanni al Sepolcro
Historic site museum in a circular medieval church, appreciated for architecture and exhibits linked to pilgrims, crusaders, and the city’s past.
- Must visit
Lungomare Regina Margherita
Brindisi’s main waterfront promenade, ideal for harbor views, evening walks, and seeing the city’s maritime life at its most atmospheric.
- Must visit
Piazza Duomo
Historic square beside the cathedral, Roman column, and staircase, making it one of the most important and scenic urban spaces in Brindisi.
- Recommended
Piazza della Vittoria
Elegant central square framed by historic buildings and cafés nearby, a practical base for sightseeing and people-watching in the old town.
- Vegetarian
Rustico Leccese
Rustico leccese is a flaky pastry filled with béchamel, tomato, and mozzarella. Popular across Salento, it is a beloved snack in Brindisi bars and bakeries.
Puccia Salentina
Puccia salentina is a round Apulian bread sandwich, often stuffed with tuna, olives, capers, or vegetables. It is a classic street food in Brindisi and nearby Salento.
- Vegetarian
- Vegan
- Gluten-free
Fave E Cicorie
Fave e cicorie pairs creamy pureed fava beans with wild chicory. This humble Puglian staple is deeply traditional and widely eaten in Brindisi homes and trattorias.
Betty Cafe Ristorante
Refined seafood restaurant in central Brindisi, known for elegant tasting menus, polished service, and creative Apulian cuisine in a stylish setting.
La Locanda del Porto
Well-known traditional restaurant serving Apulian seafood and local classics. Relaxed, reliable, and popular for fresh fish near the historic center.
La Nassa
Casual seafood spot appreciated for raw and cooked fish dishes, simple local preparations, and an unfussy atmosphere close to the waterfront.
Euro (€)
Moderate for Italy. Hotels and dining are usually cheaper than Rome or Milan, while local buses and casual meals stay fairly affordable for tourists.
Average meal costs
- Budget
- €8-15 for fast food or casual lunch.
- Mid-range
- €20-35 per person for a meal.
- Fine dining
- €50+ per person for upscale restaurants.
- Coffee
- €1.20-2.50 for espresso or cappuccino.
Tipping culture
Service is often included or modest. Round up or leave €1-2 at cafes, 5-10% at restaurants for good service, and round up taxi fares.
MyCicero
Get the appOfficial public transport app
Prices
- Single ticket
- €1.20
- Day pass
- : null
To the city center
Via Giuseppe Maria Galanti, Brindisi -> Brindisi Railway Station, Brindisi
- Distance
- 3 km
- Travel time
- 12 min
- Buy tickets before boarding unless the operator specifically enables onboard purchase in its app or sales channels.
- Check STP Brindisi service notices before travel, as suburban and urban timetables can vary by day and season.
FAQs: Bus from Siena to Brindisi
Find answers to the most common questions about traveling from Siena to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Siena to Brindisi can start from as little as €25 when you book in advance. The average bus ticket price for Siena to Brindisi is €79 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Siena to Brindisi is 9h 59m to travel the 386 miles (622 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Siena to Brindisi leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Siena to Brindisi leaves at 11:39 PM.
Yes, there are 3 direct buses a day from Siena to Brindisi with . Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Siena to Brindisi, you can count on Marino Autolinee, Itabus, FlixBus for the best way to get you to Brindisi. You can also check all possible bus companies who offer a service between Siena and Brindisi and compare the amenities they offer before buying a bus ticket.
When departing from Siena , you have various bus station options to start your journey from including Siena, Stazione FS (Piazzale Carlo Rosselli), Siena, Siena/Viale Pietro Toselli, Siena, P.za Gramsc, Poggibonsi, Via Salceto (Esso) . When arriving in Brindisi , you can end your journey in bus stations like Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) .Passengers board the bus most frequently from Siena, Stazione FS (Piazzale Carlo Rosselli), which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale), located 0 away from the city centre.
A trip to Brindisi from Siena is worth doing but not as a day trip with a journey time of 9h 59m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Siena to Brindisi is February.
It's helpful to compare your options as there are 3 ways to travel between Siena and Brindisi including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Siena to Brindisi:
- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
Yes, there are bathrooms on board the bus from Siena to Brindisi for bus company Marino Autolinee, Itabus, FlixBus.
Whether you can cancel your bus ticket from Siena to Brindisi depends on the bus companies:
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Yes, bikes are allowed on board the bus with bus company Marino Autolinee, Itabus, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Siena to Brindisi.
Yes, the following luggage options are included when booking a bus ticket from Siena to Brindisi:
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
Yes, the following additional luggage options are available when booking a bus ticket from Siena to Brindisi:
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
Yes, you can bring your pet on the bus from Siena to Brindisi. The following conditions apply:
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
You can reserve your seat on the bus from Siena to Brindisi with the following bus company: Marino Autolinee, Itabus, FlixBus
Yes, there are USB plugs on board the bus from Siena to Brindisi with the following bus company: Marino Autolinee, Itabus, FlixBus.
Yes, there is Wifi on board the bus from Siena to Brindisi with the following bus company: Marino Autolinee, Itabus, FlixBus.
Since both Siena and Brindisi are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the bus as it is the most popular way to get from Siena to Brindisi among Omio's users.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Brindisi, travelers should be cautious of pickpocketing, especially in crowded areas like the port and public transport hubs. Common scams include overpriced taxi rides and unlicensed tour operators. It's advisable to use official transportation services and remain vigilant with personal belongings in busy spots.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Siena to Brindisi
Most Siena to Brindisi buses use the Siena, Stazione FS (Piazzale Carlo Rosselli) to Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) station pair. Use this guide to compare Siena and Brindisi bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Siena
Arrival bus stations in Brindisi
Which Siena station do buses to Brindisi leave from?
Buses from Siena to Brindisi leave from Siena, Stazione FS (Piazzale Carlo Rosselli). The station is 0 miles (1 km) from Siena city centre at Siena - Ferrovia, 53100 Siena SI, Italy.
Siena, Stazione FS (Piazzale Carlo Rosselli)Siena - Ferrovia, 53100 Siena SI, Italy
City-centre transport
Getting to Siena, Stazione FS (Piazzale Carlo Rosselli) from Siena city centre
Siena, Stazione FS (Piazzale Carlo Rosselli) is 1 km from Siena city centre. Public transport options include:
BusS10, 0S3, 544 · 7m · €1 · every ~6 min
Siena, Stazione FS (Piazzale Carlo Rosselli) bus station facilities and services
Siena, Stazione FS (Piazzale Carlo Rosselli) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Cafeteria and vending machines available.
Wi-Fi and ATMs
Wi-Fi is available at Siena, Stazione FS (Piazzale Carlo Rosselli). ATMs are available at Siena, Stazione FS (Piazzale Carlo Rosselli).
Tickets and information
Ticket office support is available at Siena, Stazione FS (Piazzale Carlo Rosselli).
Parking, taxis and toilets
Available at Siena, Stazione FS (Piazzale Carlo Rosselli): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Siena, Stazione FS (Piazzale Carlo Rosselli): Wheelchair ramps are provided.
Siena, Siena/Viale Pietro ToselliViale Pietro Toselli, 53100 Siena SI, Italy
City-centre transport
Getting to Siena, Siena/Viale Pietro Toselli from Siena city centre
Siena, Siena/Viale Pietro Toselli is 1 km from Siena city centre. Public transport options include:
BusS52 · 14m · €1 · every ~5 min
Siena, Siena/Viale Pietro Toselli bus station facilities and services
Siena, Siena/Viale Pietro Toselli has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Nearby cafes and fast food available.
Wi-Fi and ATMs
Wi-Fi is available at Siena, Siena/Viale Pietro Toselli. ATMs are available at Siena, Siena/Viale Pietro Toselli.
Tickets and information
Ticket office support is available at Siena, Siena/Viale Pietro Toselli.
Parking, taxis and toilets
Available at Siena, Siena/Viale Pietro Toselli: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Siena, Siena/Viale Pietro Toselli: Ramps and accessible paths available.
Siena, P.za GramscPiazza Gramsci (Arrivo), 53100 Siena SI, Italy
City-centre transport
Getting to Siena, P.za Gramsc from Siena city centre
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Siena, P.za Gramsc bus station facilities and services
Siena, P.za Gramsc has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Siena, P.za Gramsc. ATMs are available at Siena, P.za Gramsc.
Tickets and information
Ticket office support is available at Siena, P.za Gramsc.
Parking, taxis and toilets
Available at Siena, P.za Gramsc: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Siena, P.za Gramsc: The station is accessible with ramps and lowered curbs.
Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)Brindisi Falcone Professional Institute, Via Giuseppe Maria Galanti 8, 72100
Most popular bus connections from Siena
More options for your journey from Siena to Brindisi
Here are some other resources that might have the information you need
Most popular buses to and from Brindisi and Siena
Most popular bus connections to Brindisi
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