Siena to Brindisi bus with Marino Autolinee

Tue, Aug 04
+ Add return
Marino Autolinee
Itabus
FlixBus
Alsa
BlaBlaCar Bus
2,000+ travel companies
Marino Autolinee
Itabus
FlixBus
Alsa
BlaBlaCar Bus
2,000+ travel companies
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The cheapest and fastest buses from Siena to Brindisi

Showing times and prices for Aug 04

Cheapest price

$43

Average price

$67

Fastest journey

11 h

Average duration

12 h 25 m

Buses per day

4

Distance

622 km

Cheap tickets

The best way to find a cheap bus ticket from Siena to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Siena to Brindisi will cost around $67 if you buy it on the day, but the cheapest tickets can be found for only $43.

Fast buses

Of the 4 buses that leave Siena for Brindisi on Tue, Aug 04, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Tue, Aug 04 the direct buses cover the 622 km distance in an average of 12 h 25 m but if you time it right, some buses will get you there in just 11 h .

On Tue, Aug 04 the slowest buses will take 15 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • FlixBus
    9:25 PM15h00
    Siena
    12:25 PMBrindisi
    $431One-way
    0 transfers
  • Marino Autolinee
    7:30 PM11h55
    Siena
    7:25 AMBrindisi
    $651One-way
    0 transfers
  • Itabus
    7:25 AM11h00
    Siena
    6:25 PMBrindisi
    $801One-way
    0 transfers
  • FlixBus
    4:25 PM11h45
    Siena
    4:10 AMBrindisi
    $811One-way
    0 transfers

Journey information

Overview: Bus from Siena to Brindisi

ItalyItaly
ItalyItaly
Icon of bus

Buses from Siena to Brindisi run on average 13 times per day, taking around 11h 2m. Cheap bus tickets for this journey start at $25 if you book in advance.

There are 2 buses per day. The earliest bus runs at 00:05, the last at 23:39. The fastest bus covers the 386 miles (622 km) distance in 11h 0m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
386 miles (622 km)
Average bus duration
11h 2m
Cheapest ticket price
$25
Buses per day
13
Direct buses
2
Fastest bus
11h 0m
First bus
12:05 AM
Last bus
11:39 PM
Cheapest Month
Feb
Cheapest Day
Sat
High Season
Jul - Sep
Low Season
Jan - Mar
Busiest Day
Tue
Least Busy Day
Mon
Best time to book
5 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Siena to Brindisi Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
12:45AM
Arrival Time
04:30PM
Duration
15h45
Departure days
Mon, Sat, Sun
Cheapest price
$95
Operator
BlaBlaCar
Departure Time
02:10AM
Arrival Time
10:00AM
Duration
7h50
Departure days
Sat
Cheapest price
$86
Operator
BlaBlaCar
Departure Time
04:20AM
Arrival Time
01:20PM
Duration
9h00
Departure days
Sat
Cheapest price
$69
Operator
FlixBus
Departure Time
06:50AM
Arrival Time
06:25PM
Duration
11h35
Departure days
Mon, Sat, Sun
Cheapest price
$101
Operator
FlixBus
Departure Time
07:00AM
Arrival Time
06:25PM
Duration
11h25
Departure days
Mon, Sat, Sun
Cheapest price
$101
Operator
FlixBus
Departure Time
07:10AM
Arrival Time
06:25PM
Duration
11h15
Departure days
Mon, Sat, Sun
Cheapest price
$100
Operator
Itabus
Departure Time
07:25AM
Arrival Time
06:25PM
Duration
11h00
Departure days
Tue, Wed, Thu, Fri
Cheapest price
$25
Operator
BlaBlaCar
Departure Time
08:00AM
Arrival Time
05:30PM
Duration
9h30
Departure days
Sun
Cheapest price
$83
Operator
Itabus
Departure Time
08:25AM
Arrival Time
07:25PM
Duration
11h00
Departure days
Fri
Cheapest price
$37
Operator
FlixBus
Departure Time
08:45AM
Arrival Time
10:00PM
Duration
13h15
Departure days
Mon
Cheapest price
$88
Operator
Marino Autolinee
Departure Time
09:05AM
Arrival Time
08:10PM
Duration
11h05
Departure days
Wed
Cheapest price
$100
Operator
Itabus
Departure Time
09:25AM
Arrival Time
08:25PM
Duration
11h00
Departure days
Mon, Sat, Sun
Cheapest price
$41
Operator
Marino Autolinee
Departure Time
10:05AM
Arrival Time
09:10PM
Duration
11h05
Departure days
Thu
Cheapest price
$66
Operator
FlixBus
Departure Time
10:35AM
Arrival Time
10:25PM
Duration
11h50
Departure days
Mon, Sat, Sun
Cheapest price
$90
Operator
FlixBus
Departure Time
10:45AM
Arrival Time
10:25PM
Duration
11h40
Departure days
Mon, Sat, Sun
Cheapest price
$90
Operator
FlixBus
Departure Time
10:55AM
Arrival Time
10:25PM
Duration
11h30
Departure days
Mon, Sat, Sun
Cheapest price
$92
Operator
Marino Autolinee
Departure Time
11:05AM
Arrival Time
10:10PM
Duration
11h05
Departure days
Mon, Sat, Sun
Cheapest price
$86
Operator
FlixBus
Departure Time
02:51PM
Arrival Time
06:10AM
Duration
15h19
Departure days
Mon, Sat, Sun
Cheapest price
$90
Operator
Itabus
Departure Time
04:25PM
Arrival Time
06:25AM
Duration
14h00
Departure days
Mon, Sat, Sun
Cheapest price
$34
Operator
FlixBus
Departure Time
04:25PM
Arrival Time
04:10AM
Duration
11h45
Departure days
Tue
Cheapest price
$81
Operator
FlixBus
Departure Time
05:25PM
Arrival Time
06:15AM
Duration
12h50
Departure days
Wed
Cheapest price
$51
Operator
Itabus
Departure Time
05:50PM
Arrival Time
06:30AM
Duration
12h40
Departure days
Fri
Cheapest price
$46
Operator
FlixBus
Departure Time
06:25PM
Arrival Time
06:10AM
Duration
11h45
Departure days
Mon, Sat, Sun
Cheapest price
$90
Operator
Marino Autolinee
Departure Time
07:30PM
Arrival Time
07:25AM
Duration
11h55
Departure days
Tue, Wed
Cheapest price
$63
Operator
FlixBus
Departure Time
07:45PM
Arrival Time
07:15AM
Duration
11h30
Departure days
Mon, Sat, Sun
Cheapest price
$95
Operator
FlixBus
Departure Time
08:25PM
Arrival Time
11:55AM
Duration
15h30
Departure days
Thu
Cheapest price
$115
Operator
Marino Autolinee
Departure Time
08:30PM
Arrival Time
08:25AM
Duration
11h55
Departure days
Mon, Sat, Sun
Cheapest price
$87
Operator
FlixBus
Departure Time
09:25PM
Arrival Time
12:25PM
Duration
15h00
Departure days
Tue, Thu
Cheapest price
$43
Operator
FlixBus
Departure Time
10:25PM
Arrival Time
01:55PM
Duration
15h30
Departure days
Mon, Sat, Sun
Cheapest price
$115

Live departures

Siena to Brindisi bus times

The table below shows live departures for Siena to Brindisi buses for today, Monday, August 3. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBusFlixBus · FlixBus6:50 AM Siena, P.za Gramsc
11h35
6:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)1 transfer
FlixBusFlixBus · FlixBus7:00 AM Siena, Stazione FS (Piazzale Carlo Rosselli)
11h25
6:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)1 transfer
FlixBusFlixBus · FlixBus7:10 AM Siena, Siena/Viale Pietro Toselli
11h15
6:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)1 transfer
FlixBusFlixBus · FlixBus · FlixBus8:45 AM Siena, Stazione FS (Piazzale Carlo Rosselli)
13h15
10:00 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers
Itabus11219:25 AM Siena, Stazione FS (Piazzale Carlo Rosselli)
11h00
8:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)0 transfersDirect
FlixBusFlixBus · FlixBus · FlixBus10:35 AM Siena, P.za Gramsc
11h50
10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers
FlixBusFlixBus · FlixBus · FlixBus10:45 AM Siena, Stazione FS (Piazzale Carlo Rosselli)
11h40
10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers
FlixBusFlixBus · FlixBus · FlixBus10:55 AM Siena, Siena/Viale Pietro Toselli
11h30
10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers
Marino Autolinee20711:05 AM Siena, Stazione FS (Piazzale Carlo Rosselli)
11h05
10:10 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)0 transfersDirect
FlixBusFlixBus · FlixBus · FlixBus2:51 PM Siena, Siena/Viale Pietro Toselli
15h19
6:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers
Itabus2125 · 11074:25 PM Siena, Stazione FS (Piazzale Carlo Rosselli)
14h00
6:25 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)1 transfer
FlixBusFlixBus · FlixBus6:25 PM Siena, Stazione FS (Piazzale Carlo Rosselli)
11h45
6:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)1 transfer
FlixBusFlixBus · FlixBus7:45 PM Siena, Stazione FS (Piazzale Carlo Rosselli)
11h30
7:15 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)1 transfer
Marino Autolinee1088:30 PM Siena, Stazione FS (Piazzale Carlo Rosselli)
11h55
8:25 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)0 transfersDirect
FlixBusFlixBus · FlixBus · FlixBus10:25 PM Siena, Stazione FS (Piazzale Carlo Rosselli)
15h30
1:55 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers

Find all the dates and times for this journey

Why should you book Siena to Brindisi buses with Omio?

Marino Autolinee as well as Itabus or FlixBus offer buses services from Siena to Brindisi.
Omio is an official ticket reseller for all your travel options from Siena to Brindisi.

Why book with Omio vs Marino Autolinee?

  • Compare with other providers: On Omio, you can not only buy tickets for Marino Autolinee, but also compare tickets for the likes of Itabus or FlixBus to find the best option for your trip from Siena to Brindisi.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Marino Autolinee with all available travel options, which are bus and train to ensure you get the best deal for traveling from Siena to Brindisi.

Why book with Omio over Checkmybus, Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus or FlixBus to find the best option for your trip from Siena to Brindisi.
  • Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Siena to Brindisi.

Bus providers: Marino Autolinee, Itabus, FlixBus from Siena to BrindisiYou can travel by bus between Siena to Brindisi with Marino Autolinee, Itabus, FlixBus for as low as $25. When you search for schedules and tickets, Omio will show you the best journey

Marino Autolinee

About
MarinoBus is an Italian bus company with more than 200 destinations and 6,000 connections across Italy and Europe. Originally focused on Basilicata and Apulia, its network has expanded to cover the rest of Italy as well as Switzerland, France, Germany, and Luxembourg. All MarinoBus coaches are equipped with spacious reclining seats, air conditioning, onboard restrooms, WiFi, minibars, and color TVs. For your next trip, you can book the standard ticket, which includes one piece of hand luggage and up to two checked bags per passenger
Luggage & cancellation policy
Average Duration
11h 5m
Cheapest Price
$60
Luggage included
One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
10€ per additional bag up to 20 kg.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.

Itabus

About
Itabus is a leading bus company in Italy, providing reliable and comfortable transportation services to its customers. Itabus operates a fleet of modern buses, ranging from luxury coaches to standard buses, all equipped with air conditioning, comfortable seating, and onboard entertainment.
Luggage & cancellation policy
Average Duration
10h 45m
Cheapest Price
$25
Itabus frequency
1 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 20kg.
Additional luggage
5€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Dedicated seating areas; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
11h 30m
Cheapest Price
$39
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Complete guide to Brindisi

Things to do in Brindisi

Discover the best of Brindisi — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brindisi trip today.

  • Must visit

Museo Archeologico Provinciale Francesco Ribezzo

Main civic museum with archaeology, sculptures, and local history collections that provide the best introduction to Brindisi and its territory.

  • Recommended

Area Archeologica di San Pietro degli Schiavoni

Archaeological zone and small interpretive museum preserving a Roman domus with mosaics, ideal for understanding everyday life in ancient Brindisi.

  • Recommended

Chiesa di San Giovanni al Sepolcro

Historic site museum in a circular medieval church, appreciated for architecture and exhibits linked to pilgrims, crusaders, and the city’s past.

Euro (€)

Moderate for Italy. Hotels and dining are usually cheaper than Rome or Milan, while local buses and casual meals stay fairly affordable for tourists.

Average meal costs

Budget
€8-15 for fast food or casual lunch.
Mid-range
€20-35 per person for a meal.
Fine dining
€50+ per person for upscale restaurants.
Coffee
€1.20-2.50 for espresso or cappuccino.

Tipping culture

Service is often included or modest. Round up or leave €1-2 at cafes, 5-10% at restaurants for good service, and round up taxi fares.

FAQs: Bus from Siena to Brindisi

Find answers to the most common questions about traveling from Siena to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Siena to Brindisi can start from as little as $25 when you book in advance. The average bus ticket price for Siena to Brindisi is $50 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Siena to Brindisi is 11h 0m to travel the 386 miles (622 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Siena to Brindisi leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Siena to Brindisi leaves at 11:39 PM.
Yes, there are 2 direct buses a day from Siena to Brindisi with . Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Siena to Brindisi, you can count on Marino Autolinee, Itabus, FlixBus for the best way to get you to Brindisi. You can also check all possible bus companies who offer a service between Siena and Brindisi and compare the amenities they offer before buying a bus ticket.
It's helpful to compare your options as there are 2 ways to travel between Siena and Brindisi including taking a bus and train.
Yes, there are bathrooms on board the bus from Siena to Brindisi for bus company Marino Autolinee, Itabus, FlixBus.
Yes, the following accessibility options are available when taking the bus from Siena to Brindisi:
  • Marino Autolinee
    • Assistance
    • Priority seating
    • Accessible restrooms.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
  • Itabus
    • Assistance
    • Dedicated seating areas
    • Accessible restrooms.
Whether you can cancel your bus ticket from Siena to Brindisi depends on the bus companies:
  • Marino Autolinee
    • You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
  • Itabus
    • You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Yes, bikes are allowed on board the bus with bus company Marino Autolinee, Itabus, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Siena to Brindisi.
Yes, the following luggage options are included when booking a bus ticket from Siena to Brindisi:
  • Marino Autolinee
    • One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
  • Itabus
    • One carry-on bag up to 10kg and one checked bag up to 20kg.
Yes, the following additional luggage options are available when booking a bus ticket from Siena to Brindisi:
  • Marino Autolinee
    • 10€ per additional bag up to 20 kg.
  • FlixBus
    • Additional luggage can be purchased for a fee.
  • Itabus
    • 5€ per additional bag.
Yes, you can bring your pet on the bus from Siena to Brindisi. The following conditions apply:
  • Marino Autolinee
    • Small pets allowed in carriers
    • larger pets must be leashed and muzzled.
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
  • Itabus
    • Small pets allowed in carriers
    • larger pets must be leashed and muzzled.
You can reserve your seat on the bus from Siena to Brindisi with the following bus company: Marino Autolinee, Itabus, FlixBus
Yes, there are USB plugs on board the bus from Siena to Brindisi with the following bus company: Marino Autolinee, Itabus, FlixBus.
Yes, there is Wifi on board the bus from Siena to Brindisi with the following bus company: Marino Autolinee, Itabus, FlixBus.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Brindisi, travelers should be cautious of pickpocketing, especially in crowded areas like the port and public transport hubs. Common scams include overpriced taxi rides and unlicensed tour operators. It's advisable to use official transportation services and remain vigilant with personal belongings in busy spots.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Siena to Brindisi

Most Siena to Brindisi buses use the Siena, Stazione FS (Piazzale Carlo Rosselli) to Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) station pair, with some services arriving at Brindisi. Use this guide to compare Siena and Brindisi bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Siena
Arrival bus stations in Brindisi
Siena, Stazione FS (Piazzale Carlo Rosselli)
City-centre transport

Getting to Siena, Stazione FS (Piazzale Carlo Rosselli) from Siena city centre

BusS10, 0S3, 544 · 7m · $1 · every ~6 min
Siena, Siena/Viale Pietro Toselli
City-centre transport

Getting to Siena, Siena/Viale Pietro Toselli from Siena city centre

BusS52 · 14m · $1 · every ~5 min
Siena, P.za Gramsc

More options for your journey from Siena to Brindisi

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