Siena to Brindisi bus with Marino Autolinee

Sat, Dec 06
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Marino Autolinee
Itabus
FlixBus
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Marino Autolinee
Itabus
FlixBus
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1,000+ travel companies
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The cheapest and fastest buses from Siena to Brindisi

Showing times and prices for Dec 08

Cheapest price

€47

Average price

€47

Fastest journey

12 h 50 m

Average duration

12 h 50 m

Buses per day

1

Distance

622 km

Cheap tickets

The best way to find a cheap bus ticket from Siena to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Siena to Brindisi will cost around €47 if you buy it on the day, but the cheapest tickets can be found for only €47.

Fast buses

Of the 1 buses that leave Siena for Brindisi on Mon, Dec 08, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Mon, Dec 08 the direct buses cover the 622 km distance in an average of 12 h 50 m but if you time it right, some buses will get you there in just 12 h 50 m .

On Mon, Dec 08 the slowest buses will take 12 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

Itabus
04:40PM12h50
Siena
05:30AMBrindisi
€471One-way
0 transfers

Travel Information

Compare train, bus, and flight for Siena to Brindisi

Omio recommends booking the bus as it is the most popular option from Siena to Brindisi among Omio's users. If you are prioritising price take the bus with prices starting from €15. For those with little time consider booking a flight which can get you there in 4h 32m. The ticket price range depends on the travel mode: a bus costs an average of €15, and a flight costs an average of €20.

Distance: 386 miles (622 km)

Compare bus with

Most popular
Bus
Train
Flight

€38

Average price

Cheapest

€78

Average price

€100

Average price

11h 31m

Average total duration

11h 1m

Onboard

+

30m

Additional time*

10h 31m

Average total duration

10h 1m

Onboard

+

30m

Additional time*

7h 32m

Average total duration

Fastest

4h 32m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Siena to Brindisi Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
12:45AM
Arrival Time
04:45PM
Duration
16h00
Departure days
Sun
Cheapest price
€99
Operator
FlixBus
Departure Time
05:35AM
Arrival Time
06:25PM
Duration
12h50
Departure days
Thu, Sun
Cheapest price
€59
Operator
FlixBus
Departure Time
07:05AM
Arrival Time
09:40PM
Duration
14h35
Departure days
Sun
Cheapest price
€107
Operator
FlixBus
Departure Time
08:15AM
Arrival Time
09:40PM
Duration
13h25
Departure days
Sun
Cheapest price
€93
Operator
FlixBus
Departure Time
08:25AM
Arrival Time
09:40PM
Duration
13h15
Departure days
Sun
Cheapest price
€93
Operator
Itabus
Departure Time
09:00AM
Arrival Time
07:40PM
Duration
10h40
Departure days
Sun
Cheapest price
€43
Operator
Marino Autolinee
Departure Time
11:05AM
Arrival Time
10:10PM
Duration
11h05
Departure days
Thu, Sun
Cheapest price
€67
Operator
FlixBus
Departure Time
02:51PM
Arrival Time
07:15AM
Duration
16h24
Departure days
Thu, Sun
Cheapest price
€56
Operator
FlixBus
Departure Time
06:25PM
Arrival Time
06:10AM
Duration
11h45
Departure days
Thu, Sun
Cheapest price
€79
Operator
Itabus
Departure Time
06:35PM
Arrival Time
10:00AM
Duration
15h25
Departure days
Thu, Sun
Cheapest price
€29
Operator
Itabus
Departure Time
06:50PM
Arrival Time
08:30AM
Duration
13h40
Departure days
Thu
Cheapest price
€31
Operator
FlixBus
Departure Time
07:45PM
Arrival Time
07:15AM
Duration
11h30
Departure days
Thu, Sun
Cheapest price
€61
Operator
Marino Autolinee
Departure Time
08:30PM
Arrival Time
08:25AM
Duration
11h55
Departure days
Thu, Sun
Cheapest price
€61
Operator
FlixBus
Departure Time
09:45PM
Arrival Time
01:25PM
Duration
15h40
Departure days
Sun
Cheapest price
€96
Operator
FlixBus
Departure Time
10:25PM
Arrival Time
01:25PM
Duration
15h00
Departure days
Thu, Sun
Cheapest price
€52

Live departures

Siena to Brindisi bus times

The table below shows live departures for Siena to Brindisi buses for today, Sunday, December 7. You can also manually refresh the results below to see updated bus journeys.

Last updated at 10:31 AM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbusFlixBus · FlixBus · FlixBus1:51 PM Siena, Siena/Viale Pietro Toselli
15h19
5:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers
meinfernbus_flixbusFlixBus · FlixBus5:25 PM Siena, Stazione FS (Piazzale Carlo Rosselli)
11h45
5:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)1 transfer
itab2490 · 22035:35 PM Siena, Stazione FS (Piazzale Carlo Rosselli)
15h25
9:00 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)1 transfer
meinfernbus_flixbusFlixBus · FlixBus6:45 PM Siena, Stazione FS (Piazzale Carlo Rosselli)
11h30
6:15 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)1 transfer
marino_autolinee1087:30 PM Siena, Stazione FS (Piazzale Carlo Rosselli)
11h55
7:25 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)0 transfersDirect
meinfernbus_flixbusFlixBus · FlixBus · FlixBus8:45 PM Siena, Siena/Viale Pietro Toselli
15h40
12:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus9:25 PM Siena, Stazione FS (Piazzale Carlo Rosselli)
15h00
12:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Siena to Brindisi by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
Dec 08
Tue
Dec 09
Wed
Dec 10
Thu
Dec 11
Fri
Dec 12
Sat
Dec 13
Sun
Dec 14

Journey information

Overview: Bus from Siena to Brindisi

ItalyItaly
ItalyItaly
Icon of bus

Buses from Siena to Brindisi run on average 14 times per day, taking around 11h 1m. Cheap bus tickets for this journey start at $19 (€15) if you book in advance.

There are 2 buses per day. The earliest bus runs at 00:05, the last at 23:39. The fastest bus covers the 386 miles (622 km) distance in 10h 40m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
386 miles (622 km)
Average bus duration
11h 1m
Cheapest ticket price
$19 (€15)
Buses per day
14
Direct buses
2
Fastest bus
10h 40m
First bus
00:05
Last bus
23:39
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Marino Autolinee, Itabus, FlixBus from Siena to BrindisiYou can travel by bus between Siena to Brindisi with Marino Autolinee, Itabus, FlixBus for as low as $19 (€15). When you search for schedules and tickets, Omio will show you the best journey

Marino Autolinee

About
MarinoBus is an Italian bus company with more than 200 destinations and 6,000 connections across Italy and Europe. Originally focused on Basilicata and Apulia, its network has expanded to cover the rest of Italy as well as Switzerland, France, Germany, and Luxembourg. All MarinoBus coaches are equipped with spacious reclining seats, air conditioning, onboard restrooms, WiFi, minibars, and color TVs. For your next trip, you can book the standard ticket, which includes one piece of hand luggage and up to two checked bags per passenger
Luggage & cancellation policy
Average Duration
10h 55m
Cheapest Price
$51 (€41)
Marino Autolinee frequency
2 a day
Luggage included
One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
10€ per additional bag up to 20 kg.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.
Learn more about Marino Autolinee

Itabus

About
Itabus is a leading bus company in Italy, providing reliable and comfortable transportation services to its customers. Itabus operates a fleet of modern buses, ranging from luxury coaches to standard buses, all equipped with air conditioning, comfortable seating, and onboard entertainment.
Luggage & cancellation policy
Average Duration
10h 45m
Cheapest Price
$68 (€55)
Itabus frequency
2 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 20kg.
Additional luggage
5€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Dedicated seating areas; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.
Learn more about Itabus

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
15h 0m
Cheapest Price
$34 (€27)
FlixBus frequency
10 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

FAQs: Bus from Siena to Brindisi

Find answers to the most common questions about traveling from Siena to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Siena to Brindisi can start from as little as $17 (€14) when you book in advance. The average bus ticket price for Siena to Brindisi is $45 (€36); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The bus time to Brindisi from Siena is on average 10 h 55 min   for the 386 mile (622 km) long journey, but the time it takes to go from Siena to Brindisi by bus can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Siena to Brindisi leaves at 12: 05AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Siena to Brindisi leaves at 11: 39PM.
Yes, there are 2 direct buses a day from Siena to Brindisi with Marino Autolinee. Schedules can vary on holidays or weekends with fewer direct buses.
Take the Siena to Brindisi bus with Marino Autolinee, FlixBus or Itabus. However, it's always good to check out all possible bus companies for the route from Siena to Brindisi as there might be differences in the amenities they offer.

Passengers board the bus most frequently from Siena, Stazione FS (Piazzale Carlo Rosselli), which is located around 1.5 miles (2.4 km) away from the city centre, and they get off the bus at Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale), located 0.6 miles (1 km) away from the city centre.

The cheapest month for a bus from Siena to Brindisi is November.
You have options as you can travel from Siena to Brindisi 3 different ways: train, bus or flight.
Yes, the following accessibility options are available when taking the bus from Siena to Brindisi:
  • Marino Autolinee
    • Assistance
    • Priority seating
    • Accessible restrooms.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
  • Itabus
    • Assistance
    • Dedicated seating areas
    • Accessible restrooms.
Yes, there are bathrooms on board the bus from Siena to Brindisi for bus companies Marino Autolinee, FlixBus and Itabus.
Yes, bikes are allowed on board the bus with bus companies Marino Autolinee, FlixBus and Itabus.
Whether you can cancel your bus ticket from Siena to Brindisi depends on the bus providers:
  • Marino Autolinee
    • You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
  • Itabus
    • You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.

To find the cheapest bus tickets for your trip from Siena to Brindisi, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Siena to Brindisi.
    Yes, the following luggage options are included when booking a bus ticket from Siena to Brindisi:
    • Marino Autolinee
      • One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    • Itabus
      • One carry-on bag up to 10kg and one checked bag up to 20kg.
    Yes, the following additional luggage options are available when booking a bus ticket from Siena to Brindisi:
    • Marino Autolinee
      • 10€ per additional bag up to 20 kg.
    • FlixBus
      • Additional luggage can be purchased for a fee.
    • Itabus
      • 5€ per additional bag.
    Yes, you can bring your pet on the bus from Siena to Brindisi. The following conditions apply:
    • Marino Autolinee
      • Small pets allowed in carriers
      • Larger pets must be leashed and muzzled.
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    • Itabus
      • Small pets allowed in carriers
      • Larger pets must be leashed and muzzled.
    You can reserve your seat on the bus from Siena to Brindisi with the following bus companies: Marino Autolinee, FlixBus and Itabus
    Yes, there are USB plugs on board the bus from Siena to Brindisi with the following bus companies: Marino Autolinee, FlixBus and Itabus.
    Yes, there is Wifi on board the bus from Siena to Brindisi with the following bus companies: Marino Autolinee, FlixBus and Itabus.

    popular bus stations

    Popular bus stations from Siena to Brindisi

    Siena
    Brindisi
    The major bus station for departures in Siena is Siena, Stazione FS (Piazzale Carlo Rosselli). Find all the information you need to know about services, amenities and connections at Siena, Stazione FS (Piazzale Carlo Rosselli) for your trip from Siena to Brindisi.
    Siena, Stazione FS (Piazzale Carlo Rosselli)
    information
    Siena, P.za Gramsc
    information
    Siena, Siena/Viale Pietro Toselli
    information

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