4.9
4.6The cheapest and fastest buses from Siena to Brindisi
Cheapest price
$42
Average price
$52
Fastest journey
12 h 10 m
Average duration
12 h 38 m
Buses per day
3
Distance
622 km
The best way to find a cheap bus ticket from Siena to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Siena to Brindisi will cost around $52 if you buy it on the day, but the cheapest tickets can be found for only $42.
Of the 3 buses that leave Siena for Brindisi on Sun, Feb 01, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Feb 01 the direct buses cover the 622 km distance in an average of 12 h 38 m but if you time it right, some buses will get you there in just 12 h 10 m .
On Sun, Feb 01 the slowest buses will take 12 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Travel Information
Compare train, bus, and flight for Siena to Brindisi
Omio recommends booking the bus as it is the most popular option from Siena to Brindisi among Omio's users. If you are prioritising price take the bus with prices starting from €15. For those with little time consider booking a flight which can get you there in 4h 32m. The ticket price range depends on the travel mode: a bus costs an average of €15, and a flight costs an average of €20.
Distance: 386 miles (622 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
€38 Average price Cheapest | €78 Average price | €100 Average price |
11h 31m Average total duration 11h 1m Onboard + 30m Additional time* | 10h 31m Average total duration 10h 1m Onboard + 30m Additional time* | 7h 32m Average total duration Fastest 4h 32m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Siena to Brindisi bus times
The table below shows live departures for Siena to Brindisi buses for today, Saturday, January 31. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 4:40 PM Siena | 12h50 | 5:30 AM Brindisi | 0 transfersDirect | |
 | 7:20 PM Siena | 15h50 | 11:10 AM Brindisi | 0 transfersDirect | |
| Sunday, February 1 | |||||
| 3:05 AM Siena | 12h55 | 4:00 PM Brindisi | 0 transfersDirect | |
| 3:50 AM Siena | 12h10 | 4:00 PM Brindisi | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Siena to Brindisi by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 01
Feb 02
Feb 03
Feb 04
Feb 05
Feb 06
Feb 07
Why should you book Siena to Brindisi buses with Omio?
Why book with Omio vs Marino Autolinee?
- Compare with other providers: On Omio, you can not only buy tickets for Marino Autolinee, but also compare tickets for the likes of Itabus or FlixBus to find the best option for your trip from Siena to Brindisi.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Marino Autolinee with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Siena to Brindisi.
Why book with Omio over Checkmybus or Wanderu?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus or FlixBus to find the best option for your trip from Siena to Brindisi.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Siena to Brindisi.
Journey information
Overview: Bus from Siena to Brindisi
ItalyItaly
Buses from Siena to Brindisi run on average 14 times per day, taking around 11h 1m. Cheap bus tickets for this journey start at $19 (€15) if you book in advance.
There are 2 buses per day. The earliest bus runs at 00:05, the last at 23:39. The fastest bus covers the 386 miles (622 km) distance in 10h 40m.
Distance 386 miles (622 km) |
Average bus duration 11h 1m |
Cheapest ticket price $19 (€15) |
Buses per day 14 |
Direct buses 2 |
Fastest bus 10h 40m |
First bus 00:05 |
Last bus 23:39 |
Bus providers: Marino Autolinee, Itabus, FlixBus from Siena to BrindisiYou can travel by bus between Siena to Brindisi with Marino Autolinee, Itabus, FlixBus for as low as $19 (€15). When you search for schedules and tickets, Omio will show you the best journey
Marino Autolinee
Itabus
FlixBus
FAQs: Bus from Siena to Brindisi
Find answers to the most common questions about traveling from Siena to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.
- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Siena to Brindisi
Most popular bus connections from Siena
More options for your journey from Siena to Brindisi
Here are some other resources that might have the information you need
Most popular buses to and from Brindisi and Siena
Most popular bus connections to Brindisi
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