- Must visit
Royal Museums of Fine Arts of Belgium
Major museum complex with Old Masters, Magritte works, and Belgian art; one of the city’s essential cultural visits.
Cheapest price
$71
Average price
$130
Fastest journey
20 h 30 m
Average duration
21 h 8 m
Buses per day
13
Distance
1316 km
The best way to find a cheap bus ticket from Madrid to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Madrid to Brussels will cost around $130 if you buy it on the day, but the cheapest tickets can be found for only $71.
It's difficult to get from Madrid to Brussels without transferring at least once.
Normal · Normal
Normal · Normal
3160 · 50100
3162 · 50321
4004 · 1657
4004 · 1657
3162 · 50321
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Madrid to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $56. For those with little time consider booking a flight which can get you there in 4h 4m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.3 - 3.3kg. The ticket price range depends on the travel mode: a bus costs an average of $56, and a train costs an average of $497.
Distance: 817 miles (1316 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$102 Average price Cheapest | $277 Average price | $503 Average price | $312 Average price (fuel + tolls) |
18h 8m Average total duration 17h 38m Onboard + 30m Additional time* | 7h 4m Average total duration Fastest 4h 4m Onboard + 3h 0m Additional time* | 21h 13m Average total duration 20h 43m Onboard + 30m Additional time* | 16h 17m Average total duration (door-to-door) |
1.3 - 3.3kg CO2 emissions Lowest | 3.9 - 7.9kg CO2 emissions | - CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Madrid to Brussels:
A bus is $175 (€143) less than a flight for this route with tickets for a flight from Madrid to Brussels costing on average $277 (€226).
A bus is $401 (€327) less than a train for this route with tickets for a train from Madrid to Brussels costing on average $503 (€411).
Other travel options to Brussels take longer:
Bus takes on average 17h 38m.
Train takes on average 20h 43m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:50PM | Arrival Time 01:40PM | Duration 22h50 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $113 |
Operator BlaBlaCar Bus | Departure Time 03:30PM | Arrival Time 12:00PM | Duration 20h30 | Departure days Everyday | Cheapest price $73 |
Operator Internorte | Departure Time 03:30PM | Arrival Time 02:10PM | Duration 22h40 | Departure days Wed, Fri, Sun | Cheapest price $66 |
Operator Alsa | Departure Time 03:30PM | Arrival Time 02:10PM | Duration 22h40 | Departure days Wed, Fri, Sun | Cheapest price $66 |
Operator FlixBus | Departure Time 03:55PM | Arrival Time 03:35PM | Duration 23h40 | Departure days Tue, Thu, Sat | Cheapest price $82 |
Operator FlixBus | Departure Time 04:40PM | Arrival Time 03:35PM | Duration 22h55 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $81 |
Operator BlaBlaCar Bus | Departure Time 06:35PM | Arrival Time 05:30PM | Duration 22h55 | Departure days Everyday | Cheapest price $60 |
Operator FlixBus | Departure Time 08:25PM | Arrival Time 05:55PM | Duration 21h30 | Departure days Everyday | Cheapest price $98 |
Operator FlixBus | Departure Time 08:50PM | Arrival Time 05:55PM | Duration 21h05 | Departure days Everyday | Cheapest price $111 |
Operator BlaBlaCar Bus | Departure Time 10:30PM | Arrival Time 08:50PM | Duration 22h20 | Departure days Everyday | Cheapest price $67 |
Operator FlixBus | Departure Time 10:35PM | Arrival Time 01:10AM | Duration 26h35 | Departure days Everyday | Cheapest price $81 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 01:10AM | Duration 26h15 | Departure days Everyday | Cheapest price $95 |
The table below shows live departures for Madrid to Brussels buses for today, Thursday, June 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 2:50 PM Madrid, Estación Sur de Autobuses | 21h55 | 12:45 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
4004 · 1657 | 3:30 PM Madrid, Estación Sur de Autobuses | 20h30 | 12:00 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 3:55 PM Madrid, Estación Sur de Autobuses | 23h55 | 3:50 PM Brussels, Gare Du Midi | 1 transfer | |
FlixBus · FlixBus · FlixBus | 3:55 PM Madrid, Estación Sur de Autobuses | 23h40 | 3:35 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:55 PM Madrid, Estación Sur de Autobuses | 23h50 | 3:45 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:55 PM Madrid, Estación Sur de Autobuses | 25h20 | 5:15 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 3:55 PM Madrid, Estación Sur de Autobuses | 30h15 | 10:10 PM Brussels, Avenue des Magnolias (King Baudouin) | 3 transfers | |
FlixBus · FlixBus | 4:40 PM Madrid, Estación Sur de Autobuses | 23h10 | 3:50 PM Brussels, Gare Du Midi | 1 transfer | |
FlixBus · FlixBus | 4:40 PM Madrid, Estación Sur de Autobuses | 22h55 | 3:35 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:40 PM Madrid, Estación Sur de Autobuses | 29h30 | 10:10 PM Brussels, Avenue des Magnolias (King Baudouin) | 2 transfers | |
3162 · 50321 | 6:35 PM Madrid, Estación Sur de Autobuses | 20h40 | 3:15 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 8:25 PM Madrid, Estación Sur de Autobuses | 21h30 | 5:55 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 8:50 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 21h05 | 5:55 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 8:50 PM Madrid, Estación Sur de Autobuses | 26h40 | 11:30 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
3160 · 50100 | 10:30 PM Madrid, Estación Sur de Autobuses | 22h20 | 8:50 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 10:35 PM Madrid, Estación Sur de Autobuses | 26h35 | 1:10 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 10:55 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 26h15 | 1:10 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Madrid to Brussels run on average 10 times per day, taking around 17h 38m. Cheap bus tickets for this journey start at $56 (€46) if you book in advance.
The earliest bus runs at 00:40, the last at 23:55. The fastest bus covers the 817 miles (1316 km) distance in 20h 30m.
Distance 817 miles (1316 km) |
Average bus duration 17h 38m |
Cheapest ticket price $56 (€46) |
Buses per day 10 |
Fastest bus 20h 30m |
First bus 12:40 AM |
Last bus 11:55 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 21 days |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Major museum complex with Old Masters, Magritte works, and Belgian art; one of the city’s essential cultural visits.
Dedicated to René Magritte, with the world’s largest collection of his surrealist works in a central historic setting.
Celebrated museum in an Art Nouveau building, known for its global instrument collection and audio-guided displays.
Popular cultural hill and viewpoint linking the upper and lower city, especially photogenic at sunset.
Historic covered arcade of elegant passages, shops, and architecture, often highlighted in social media imagery.
Stylish square known for antiques, refined atmosphere, and easy access to nearby churches and museums.
Brussels classic of mussels steamed with white wine, celery, onions, or cream, served with crisp fries. It is one of the city’s most iconic comfort dishes.
Traditional Belgian beef and onion stew slowly cooked with dark beer, often slightly sweet-sour and served with fries or bread. A staple in Brussels brasseries.
Rustic mashed potatoes mixed with vegetables such as carrots, leeks, or spinach, often served with sausage or meat. The base preparation is a classic local side dish.
One of Brussels’ most famous fine-dining restaurants, celebrated for refined Belgian and French cuisine in an elegant Art Nouveau setting.
Respected restaurant specializing in carefully prepared Belgian cuisine and strong beer pairings, with a cozy, polished brasserie feel.
Well-known old-school restaurant serving generous Belgian specialties such as carbonnade, stoemp, and sausage in a rustic, bustling atmosphere.
Moderate by Western European standards. Food and transport are manageable, but central hotels cost more.
Service is usually included. Rounding up or leaving 5-10% for great restaurant service is appreciated, not required. Round up taxi fares; no tip is expected for bars or cafés.
Official public transport app
Brussels South (Gare du Midi), Brussels -> Brussels Central Station, Brussels
Find answers to the most common questions about traveling from Madrid to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

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