- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Cheapest price on Sep 20
$98
Average ticket price on Sep 20
$123
Fastest journey on Sep 20
12 h 55 m
Average journey duration on Sep 20
14 h 47 m
Buses on Sep 20
6
Distance
662 km
The best way to find a cheap bus ticket from Lucerne to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lucerne to Rome will cost around $123 if you buy it on the day, but the cheapest tickets can be found for only $98.
On Sun, Sep 20, we found 6 buses from Lucerne to Rome, including 1 direct services.
On Sun, Sep 20 the direct buses cover the 662 km distance in an average of 14 h 47 m but if you time it right, some buses will get you there in just 12 h 55 m .
On Sun, Sep 20 the slowest buses will take 16 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Lucerne to Rome among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $92 For those with little time, consider booking a flight, which has an average total journey time of 4h 58m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.6kg. Average ticket prices depend on the travel mode: a bus costs an average of $92, while a flight costs an average of $414.
Distance: 411 miles (662 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$92 Average price Cheapest | $414 Average price | $179 Average price | $300 Average price (fuel + tolls) |
13h 6m Average total duration 12h 36m Onboard + 30m Additional time* | 4h 58m Average total duration Fastest 2h 58m Onboard + 2h 0m Additional time* | 8h 17m Average total duration 7h 47m Onboard + 30m Additional time* | 8h 48m Average total duration (door-to-door) |
0.7 - 1.7kg CO2 emissions | 2.0 - 4.0kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Lucerne to Rome:
A bus is $87 (€71) less than a train for this route with tickets for a train from Lucerne to Rome costing on average $179 (€146).
A bus is $323 (€264) less than a flight for this route with tickets for a flight from Lucerne to Rome costing on average $414 (€339).
Other travel options to Rome take longer:
Train takes on average 7h 47m.
Bus takes on average 12h 36m.
Tickets start at around $92 (€75) compared to roughly $300 (€245) in fuel and tolls — a saving of about $208 (€170). The journey takes 12h 36m versus 8h 48m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:30AM | Arrival Time 05:50PM | Duration 16h20 | Departure days Mon, Sat, Sun | Cheapest price $79 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 09:10PM | Duration 13h55 | Departure days Mon, Fri, Sat, Sun | Cheapest price $82 |
Operator FlixBus | Departure Time 10:45AM | Arrival Time 11:40PM | Duration 12h55 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $66 |
Operator FlixBus | Departure Time 01:10PM | Arrival Time 06:05AM | Duration 16h55 | Departure days Everyday | Cheapest price $61 |
Operator RegioJet a.s. | Departure Time 07:20PM | Arrival Time 02:45PM | Duration 43h25 | Departure days Sun | Cheapest price $177 |
The table below shows live departures for Lucerne to Rome buses for today, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 10:45 AM Luzern, Landenburgstrasse (Busparkplatz) | 12h55 | 11:40 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 1:10 PM Luzern, Landenburgstrasse (Busparkplatz) | 16h55 | 6:05 AM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
| Sunday, September 20 | |||||
FlixBus · FlixBus | 1:30 AM Luzern, Landenburgstrasse (Busparkplatz) | 13h50 | 3:20 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 1:30 AM Luzern, Landenburgstrasse (Busparkplatz) | 16h20 | 5:50 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus | 7:15 AM Luzern, Landenburgstrasse (Busparkplatz) | 13h55 | 9:10 PM Roma, Autostazione Tiburtina | 1 transfer | |
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Lucerne to Rome run on average 4 times per day, taking around 12h 36m. Cheap bus tickets for this journey start at $13 (€11) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 411 miles (662 km) distance in 10h 35m.
Distance 411 miles (662 km) |
Average bus duration 12h 36m |
Cheapest ticket price $13 (€11) |
Buses per day 4 |
Direct buses 1 |
Fastest bus 10h 35m |
First bus 12:10 AM |
Last bus 11:50 PM |
Cheapest Month May |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 42 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Via Marsala, Rome -> Piazza Barberini, Rome
Find answers to the most common questions about traveling from Lucerne to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Lucerne to Rome buses use the Luzern, Landenburgstrasse (Busparkplatz) to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Lucerne and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Luzern, Landenburgstrasse (Busparkplatz) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Luzern, Landenburgstrasse (Busparkplatz). ATMs are available at Luzern, Landenburgstrasse (Busparkplatz).
Ticket office support is available at Luzern, Landenburgstrasse (Busparkplatz).
Available at Luzern, Landenburgstrasse (Busparkplatz): Parking, Taxis, WC.
Accessibility facilities are available at Luzern, Landenburgstrasse (Busparkplatz): Accessible for individuals with reduced mobility.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Here are some other resources that might have the information you need