Travel Information
Compare bus, train, and flight for Lucerne to Prague
Omio recommends booking the train as it is the most popular option from Lucerne to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $82 For those with little time, consider booking a flight, which has an average total journey time of 4h 28m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of $82, while a flight costs an average of $218.
Distance: 349 miles (562 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$133 Average price | $82 Average price Cheapest | $218 Average price | $222 Average price (fuel + tolls) |
12h 42m Average total duration 12h 12m Onboard + 30m Additional time* | 12h 48m Average total duration 12h 18m Onboard + 30m Additional time* | 4h 28m Average total duration Fastest 2h 28m Onboard + 2h 0m Additional time* | 7h 53m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | 1.7 - 3.4kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Lucerne to Prague:
A bus is $50 (€41) less than a train for this route with tickets for a train from Lucerne to Prague costing on average $133 (€108).
A bus is $135 (€109) less than a flight for this route with tickets for a flight from Lucerne to Prague costing on average $218 (€176).
Other travel options to Prague take longer:
Train takes on average 12h 42m.
Bus takes on average 12h 48m.
Tickets start at around $133 (€108) compared to roughly $222 (€180) in fuel and tolls — a saving of about $89 (€72). The journey takes 12h 12m versus 7h 53m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Lucerne to Prague
How to get from Lucerne to Prague by train, bus or flight.
Our recommendation
The best way to travel from Lucerne to Prague is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus · FlixBus3:35 PM16h55Luzern, Landenburgstrasse (Busparkplatz)8:30 AMPraha, Zličín$581One-way2 transfers
Cheapest
FlixBus · FlixBus · FlixBus3:35 PM16h55Luzern, Landenburgstrasse (Busparkplatz)8:30 AMPraha, Zličín$581One-way2 transfers
Fastest
LH1883+
LH16909:55 AM2h45Turin Airport12:40 PMPrague Vaclav Havel Airport$3941One-way1 transfer
Other options
IR 2316 · ICE 370 · ICE 567 · 8862110:54 AM11h28Lucerne station10:22 PMPrague hlavní nádraží$791One-way5 transfers
IR 2316 · ICE 370 · ICE 567 · 8862110:54 AM11h28Lucerne station10:22 PMPrague hlavní nádraží$1221One-way5 transfers
IR 2316 · ICE 370 · ICE 1653 · RJ 17910:54 AM12h37Lucerne station11:31 PMPrague hlavní nádraží$1241One-way3 transfers
FlixBus · FlixBus · FlixBus4:25 AM19h30Luzern, Landenburgstrasse (Busparkplatz)11:55 PMPrague, Central Train Station$581One-way2 transfers
FlixBus · FlixBus · FlixBus3:35 PM19h55Luzern, Landenburgstrasse (Busparkplatz)11:30 AMPrague, Central Train Station$581One-way2 transfers
FlixBus · FlixBus · FlixBus4:25 AM16h45Luzern, Landenburgstrasse (Busparkplatz)9:10 PMPraha, Na Knížecí$591One-way2 transfers
VY6513 · VY865210:20 PM11h30Turin Airport9:50 AMPrague Vaclav Havel Airport$1511One-way1 transfer
KL1638 · KL13576:05 AM11h35Turin Airport5:40 PMPrague Vaclav Havel Airport$1751One-way1 transfer
KL1638 · KL13616:05 AM16h30Turin Airport10:35 PMPrague Vaclav Havel Airport$1751One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Lucerne to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lucerne to Prague.

This is compared to other travel options from Lucerne to Prague:
A bus is $50 (€41) less than a train for this route with tickets for a train from Lucerne to Prague costing on average $133 (€108).
A bus is $135 (€109) less than a flight for this route with tickets for a flight from Lucerne to Prague costing on average $218 (€176).
Other travel options to Prague take longer:
Train takes on average 12h 42m.
Bus takes on average 12h 48m.
- Around 35 flights per day.
- Around 12 buses per day.
- Around 8 trains per day.
However, we recommend checking specific travel dates for your route between Lucerne and Prague as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Turin Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Lucerne station and arrive in Prague hlavní nádraží.
- Buses mostly depart from Luzern, Landenburgstrasse (Busparkplatz) and arrive in Prague, Central Train Station.
- Travel with FlixBus to go to Prague by bus.
- Travel with Deutsche Bahn, alex-Länderbahn und Vogtlandbahn-GmbH, České dráhy to go to Prague by train.
- Travel with KLM Cityhopper, Buzz to go to Prague by flight.
- 0 direct flights per day with Buzz.
Travelling from Lucerne to Prague: related information
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