- Must visit
National Museum
Prague’s flagship museum on Wenceslas Square, with major natural history, history, and cultural collections in a monumental Neo-Renaissance building.
Cheapest price
$188
Average price
$269
Fastest journey
11 h 27 m
Average duration
11 h 51 m
Trains per day
7
Distance
562 km
The best way to find a cheap train ticket from Lucerne to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lucerne to Prague will cost around $269 if you buy it on the day, but the cheapest tickets can be found for only $188.
It's difficult to get from Lucerne to Prague without transferring at least 2 times.
IR 2312 · ICE 372 · ICE 565 · 88619
IR 2312 · ICE 372 · ICE 1561 · RJ 385
IR 2571 · EC 99+
361
IR 2115 · rjx 165 · Sp 3806 · R 702
IR 2117 · EC 191 · EC 363
IR 2312 · ICE 372 · ICE 565 · 88619
IR 2571 · EC 99+
361
IR 2571 · EC 99 · EC 361
IR 2117 · EC 191 · EC 363
IR 2312 · ICE 372 · ICE 1561 · RJ 385Omio recommends booking the train as it is the most popular option from Lucerne to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $52. For those with little time consider booking a flight which can get you there in 2h 4m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $52, and a flight costs an average of $82.
Distance: 349 miles (562 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$136 Average price | $80 Average price Cheapest | $241 Average price | $222 Average price (fuel + tolls) |
12h 23m Average total duration 11h 53m Onboard + 30m Additional time* | 13h 3m Average total duration 12h 33m Onboard + 30m Additional time* | 5h 4m Average total duration Fastest 2h 4m Onboard + 3h 0m Additional time* | 7h 53m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | 1.7 - 3.4kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Lucerne to Prague:
A bus is $56 (€45) less than a train for this route with tickets for a train from Lucerne to Prague costing on average $136 (€109).
A bus is $161 (€130) less than a flight for this route with tickets for a flight from Lucerne to Prague costing on average $241 (€194).
Other travel options to Prague take longer:
Train takes on average 11h 53m.
Bus takes on average 12h 33m.
Tickets start at around $136 (€109) compared to roughly $222 (€179) in fuel and tolls — a saving of about $86 (€69). The journey takes 11h 53m versus 7h 53m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Lucerne to Prague trains for today, Sunday, May 31. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
IC 688 · EC 459 | On time 7:54 PM Lucerne station | 13h31 | 9:25 AM Prague hlavní nádraží | 1 transfer | |
IC 688 · EC 459 | On time 7:54 PM Lucerne station | 13h31 | 9:25 AM Prague hlavní nádraží | 1 transfer | |
| Monday, June 1 | |||||
IR 2571 · EC 99 · EC 361 | 8:35 AM Lucerne station | 11h46 | 8:21 PM Prague hlavní nádraží | 2 transfers | |
IR 2571 · EC 99+ 361 | 8:35 AM Lucerne station | 11h46 | 8:21 PM Prague hlavní nádraží | 2 transfers | |
IR 2312 · ICE 372 · ICE 1651 · rj 385 | 8:54 AM Lucerne station | 12h31 | 9:25 PM Prague hlavní nádraží | 3 transfers | |
IR 2312 · ICE 372 · ICE 1561 · RJ 385 | On time 8:54 AM Lucerne station | 12h31 | 9:25 PM Prague hlavní nádraží | 3 transfers | |
IR 2312 · ICE 372 · ICE 565 · 88619 | 8:54 AM Lucerne station | 11h27 | 8:21 PM Prague hlavní nádraží | 5 transfers | |
IR 2115 · rjx 165 · Sp 3806 · R 702 | On time 9:35 AM Lucerne station | 12h35 | 10:10 PM Prague hlavní nádraží | 3 transfers | |
IR 2117 · EC 191 · EC 363 | On time 10:35 AM Lucerne station | 11h47 | 10:22 PM Prague hlavní nádraží | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Lucerne to Prague run on average 8 times per day, taking around 11h 53m. Cheap train tickets for this journey start at $76 (€61) but you can travel from only $52 (€42) by bus.
The earliest train runs at 00:30, the last at 23:57. The fastest train covers the 349 miles (562 km) distance in 11h 27m.
Distance 349 miles (562 km) |
Average train duration 11h 53m |
Cheapest ticket price $76 (€61) |
Trains per day 8 |
Fastest train 11h 27m |
First train 12:30 AM |
Last train 11:57 PM |
Cheapest Month Jul |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Wed |
Best time to book 77 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Prague’s flagship museum on Wenceslas Square, with major natural history, history, and cultural collections in a monumental Neo-Renaissance building.
A major museum complex preserving Prague’s Jewish heritage through synagogues, ceremonial objects, archives, and cemetery access.
A leading contemporary art venue in Holešovice known for ambitious exhibitions, design, and the striking Gulliver airship installation.
Prague’s historic central square, surrounded by major landmarks and lively at all hours, making it an essential first stop.
A picturesque district of Baroque streets, embassies, gardens, and hidden corners beneath Prague Castle, ideal for walking and photography.
A broad boulevard-like square central to modern Czech history, shopping, and city life, anchored by the National Museum.
Marinated beef sirloin with creamy root-vegetable sauce, bread dumplings, cranberry sauce, and whipped cream. One of the most classic Czech celebratory dishes.
Roast pork served with bread dumplings and braised cabbage. A cornerstone of traditional Czech home cooking and pub menus.
Czech-style goulash, usually beef, slower-cooked and less soupy than the Hungarian version, commonly served with dumplings. A staple in Prague pubs.
Michelin-starred restaurant offering contemporary Czech fine dining with seasonal ingredients and a sophisticated atmosphere.
Well-known restaurant near Old Town Square offering refined Czech classics in a polished but approachable setting.
Elegant grand cafe and restaurant known for excellent breakfasts, pastries, and upscale Czech and Central European dishes.
Moderate by European standards. Beer, transit, and casual meals are affordable; central hotels cost more.
Around 10% in restaurants for good service, often rounded up. Tip taxis modestly by rounding up. Not expected for counter service, but appreciated.
Official public transport app
Prague hlavní nádraží -> Old Town Square, Prague
Find answers to the most common questions about traveling from Lucerne to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

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