Travel Information
Compare train and bus for Isernia to Rome
Omio recommends booking the train as it is the most popular option from Isernia to Rome among Omio's users. If you are prioritising price take the train with prices starting from $16. For those with little time consider booking a bus which can get you there in 2h 22m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.0 - 0.1kg. The ticket price range depends on the travel mode: a train costs an average of $16, and a bus costs an average of $10.
Distance: 92 miles (149 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$17 Average price Cheapest | $18 Average price | $49 Average price (fuel + tolls) |
3h 28m Average total duration 2h 58m Onboard + 30m Additional time* | 2h 52m Average total duration Fastest 2h 22m Onboard + 30m Additional time* | 2h 26m Average total duration (door-to-door) |
0.0 - 0.1kg CO2 emissions Lowest | 0.1 - 0.4kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Isernia to Rome:
A train is $1 (€0.97) less than a bus for this route with tickets for a bus from Isernia to Rome costing on average $18 (€15).
Other travel options to Rome take longer:
Train takes on average 2h 58m.
Travel optionsfrom Isernia to Rome
How to get from Isernia to Rome by train, bus or flight.
Our recommendation
The best way to travel from Isernia to Rome is by taking a bus because it’s the best combination of price and speed.
0598:25 AM2h25Isernia, Piazza della Repubblica (F. Martino bus station)10:50 AMRoma, Autostazione Tiburtina$61One-way0 transfers
Cheapest
0598:25 AM2h25Isernia, Piazza della Repubblica (F. Martino bus station)10:50 AMRoma, Autostazione Tiburtina$61One-way0 transfers
Fastest
Regionale 233478:38 AM2h09Isernia station10:47 AMRome Termini$171One-way0 transfers
Other options
Regionale 233416:40 AM2h13Isernia station8:53 AMRome Termini$171One-way0 transfers
Regionale 233618:35 PM2h19Isernia station10:54 PMRome Termini$171One-way0 transfers
Regionale 233513:03 PM2h24Isernia station5:27 PMRome Termini$171One-way0 transfers
FlixBus11:35 AM2h25Isernia, Piazza della Repubblica (F. Martino bus station)2:00 PMRoma, Autostazione Tiburtina$161One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Isernia to Rome
Travel to Rome easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Isernia to Rome.

This is compared to other travel options from Isernia to Rome:
A train is $1 (€0.97) less than a bus for this route with tickets for a bus from Isernia to Rome costing on average $18 (€15).
Other travel options to Rome take longer:
Train takes on average 2h 58m.
- Around 10 buses per day.
- Around 9 trains per day.
However, we recommend checking specific travel dates for your route between Isernia and Rome as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Isernia station and arrive in Rome Termini.
- Buses mostly depart from Isernia, Piazza della Repubblica (F. Martino bus station) and arrive in Roma, Autostazione Tiburtina.
- Travel with Regionale, Intercity to go to Rome by train.
- Travel with FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A. to go to Rome by bus.
- 2 direct trains per day with Regionale.
- 6 direct buses per day with FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A..
Travelling from Isernia to Rome: related information
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