Travel Information from Isernia to Rome
| 92 miles (149 km) | |
| Train or bus | |
| $7 - $15 | |
| Bus • $7 (€6) • 2 h 20 min | |
| Train • $15 (€13) • 2 h 4 min | |
| FlixBus or Regionale |
Take a train or bus to travel 92 miles (149 km) from Isernia to Rome. The most popular travel companies which serve this route are FlixBus or Regionale among others. Travelers can even take a direct bus or train from Isernia to Rome.
Travel optionsfrom Isernia to Rome
How to get from Isernia to Rome by train, bus or flight.
Our recommendation
The best way to travel from Isernia to Rome is by taking a bus because it’s the best combination of price and speed.
FlixBusCheapest
treno 23347 effettuato con bus CB805 · Regionale 23347Fastest
FlixBusOther options
treno 23349 effettuato con bus CB807 · Regionale 23349
treno 5181 effettuato con bus CB303 · Regionale 5842
treno 23351 effettuato con bus CB809 · Regionale 23351Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Isernia to Rome
Travel to Rome easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Isernia to Rome.

There are 2 options to travel to Rome from Isernia including taking a train or bus.
The cheapest way to get from Isernia to Rome is by taking a bus with average ticket prices of $7 (€6) compared to other travel options to Rome:
Taking a bus costs $8 (€7) less than taking a train, which average ticket prices of $15 (€13).
The fastest way to get to Rome from Isernia is by train with an average travel time of 2 h 4 min.
Other travel options to Rome take longer:
Bus takes 2 h 20 min on average.
You should expect to travel around 92 miles (149 km) between Isernia and Rome.
The average frequency per day from Isernia to Rome is:
- 3 buses a day.
- 5 trains per day.
However, we recommend checking specific travel dates for your journey to Rome from Isernia as scheduled services by train or bus can vary by season or day of the week.
These are the most popular departure and arrival points from Isernia to Rome:
- Buses most often depart from Isernia at Isernia, Piazza della Repubblica (F. Martino bus station) and arrive in Rome at Roma, Autostazione Tiburtina.
- Trains most often depart from Isernia at Isernia and arrive in Rome at Rome Termini.
The following travel companies offer services from Isernia to Rome:
- FlixBus or ATM Azienda di Trasporti Molisana S. P. A. Can get you to Rome by bus. You can find a good deal for bus tickets with FlixBus from Isernia to Rome for $7 (€6) on Omio.
- Regionale or Intercity can take you to Rome by train. If searching for a good deal on trains, you can find tickets for Regionale from Isernia to Rome for $15 (€13).
Yes, there are direct routes from Isernia to Rome with the following travel companies:
- You can find 3 direct buses per day to Rome with FlixBus or ATM Azienda di Trasporti Molisana S. P. A.
- You can find 4 direct trains per day to take to Rome with Regionale.
Direct services to Rome tend to save you time and add more convenience as you won't need to transfer at another stop in between, so it's worth paying attention to before booking tickets for your route.
Travelling from Isernia to Rome: related information
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