Travel Information
Compare train and bus for Isernia to Rome
Omio recommends booking the train as it is the most popular option from Isernia to Rome among Omio's users. If you are prioritising price take the train with prices starting from €14. For those with little time consider booking a bus which can get you there in 2h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.0 - 0.1kg. The ticket price range depends on the travel mode: a train costs an average of €14, and a bus costs an average of €8.
Distance: 92 miles (149 km)
Compare train with
Most popular Train | Bus |
|---|---|
€15 Average price Cheapest | €22 Average price |
3h 17m Average total duration 2h 47m Onboard + 30m Additional time* | 2h 51m Average total duration Fastest 2h 21m Onboard + 30m Additional time* |
0.0 - 0.1kg CO2 emissions Lowest | 0.1 - 0.4kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Isernia to Rome
How to get from Isernia to Rome by train, bus or flight.
Our recommendation
The best way to travel from Isernia to Rome is by taking a bus because it’s the best combination of price and speed.
treno 23347 effettuato con bus CB703Cheapest
treno 23347 effettuato con bus CB703Fastest
FlixBusOther options
Regionale 5189+
FRECCIARGENTO 8314
Regionale 5179+
FRECCIAROSSA 1000 9620
Regionale 5181+
FRECCIAROSSA 1000 9628
treno 23349 effettuato con bus CB705
treno 23341 effettuato con bus CB701
treno 23351 effettuato con bus CB707Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Isernia to Rome
Travel to Rome easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Isernia to Rome.

This is compared to other travel options from Isernia to Rome:
A bus is $7 (€6) less than a train for this route with tickets for a train from Isernia to Rome costing on average $17 (€14).
Other travel options to Rome take longer:
Train takes on average 2h 7m.
- Around 10 buses per day.
- Around 9 trains per day.
However, we recommend checking specific travel dates for your route between Isernia and Rome as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Isernia station and arrive in Rome Termini.
- Buses mostly depart from Isernia, Piazza della Repubblica (F. Martino bus station) and arrive in Roma, Autostazione Tiburtina.
- Travel with FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A. to go to Rome by bus.
- Travel with Regionale, Intercity to go to Rome by train.
- 6 direct buses per day with FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A..
- 3 direct trains per day with Regionale.
Travelling from Isernia to Rome: related information
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