- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 06:20PM | Arrival Time 12:15PM | Duration 17h55 | Departure days Fri | Cheapest price RM66 |
Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Greenville, NC to Charleston, SC run on average 1 times per day, taking around 11h 55m. Cheap bus tickets for this journey start at RM64 if you book in advance.
The earliest bus runs at 09:15, the last at 13:55. The fastest bus covers the 244 miles (394 km) distance in 11h 55m.
Distance 244 miles (394 km) |
Average bus duration 11h 55m |
Cheapest ticket price RM64 |
Buses per day 1 |
Fastest bus 11h 55m |
First bus 9:15 AM |
Last bus 1:55 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Oct - Dec |
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
Find answers to the most common questions about traveling from Greenville, NC to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

Most Greenville, NC to Charleston, SC buses use the Greenville, S Pitt St (Butterfield Transportation Center) to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Greenville, NC and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Greenville, S Pitt St (Butterfield Transportation Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free wifi available in waiting areas. ATMs are available at Greenville, S Pitt St (Butterfield Transportation Center).
Ticket office support is available at Greenville, S Pitt St (Butterfield Transportation Center).
Available at Greenville, S Pitt St (Butterfield Transportation Center): Parking, Taxis, WC.
Accessibility facilities are available at Greenville, S Pitt St (Butterfield Transportation Center): Wheelchair accessible entrances and seating areas.
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
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