Travel Information
Compare bus and train for Greenville, NC to Charleston, SC
Omio recommends booking the train as it is the most popular option from Greenville, NC to Charleston, SC among Omio's users. If you are prioritising price take the train with prices starting from €82. For those with little time consider booking a train which can get you there in 5h 22m. The ticket price range depends on the travel mode: a train costs an average of €82, and a bus costs an average of €130.
Distance: 244 miles (394 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€130 Average price | €94 Average price Cheapest |
21h 50m Average total duration 21h 20m Onboard + 30m Additional time* | 5h 52m Average total duration Fastest 5h 22m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Live departures
Greenville, NC to Charleston, SC bus times
The table below shows live departures for Greenville, NC to Charleston, SC buses for today, Friday, February 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:20 PM Greenville, NC | 21h18 | 3:38 PM Charleston, SC | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Greenville, NC to Charleston, SC by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Greenville, NC to Charleston, SC buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of to find the best option for your trip from Greenville, NC to Charleston, SC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and train to ensure you get the best deal for traveling from Greenville, NC to Charleston, SC.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Greenville, NC to Charleston, SC.
Journey information
Overview: Bus from Greenville, NC to Charleston, SC
Buses from Greenville, NC to Charleston, SC run on average 2 times per day, taking around 21h 20m. Cheap bus tickets for this journey start at $163 (€130) but you can travel from only $103 (€82) by train.
The earliest bus runs at 09:15, the last at 13:55. The fastest bus covers the 244 miles (394 km) distance in 21h 18m.
Distance 244 miles (394 km) |
Average bus duration 21h 20m |
Cheapest ticket price $163 (€130) |
Buses per day 2 |
Fastest bus 21h 18m |
First bus 09:15 |
Last bus 13:55 |
Bus providers: Greyhound from Greenville, NC to Charleston, SCYou can travel by bus between Greenville, NC to Charleston, SC with Greyhound for as low as $103 (€82). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Greenville, NC to Charleston, SC
Find answers to the most common questions about traveling from Greenville, NC to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
Most popular bus connections from Greenville, NC
More options for your journey from Greenville, NC to Charleston, SC
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