The cheapest and fastest buses from Greenville, NC to Charleston, SC
Cheapest price
$161
Average price
$161
Fastest journey
21 h 18 m
Average duration
21 h 18 m
Buses per day
1
Distance
394 km
The best way to find a cheap bus ticket from Greenville, NC to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, NC to Charleston, SC will cost around $161 if you buy it on the day, but the cheapest tickets can be found for only $161.
It's difficult to get from Greenville, NC to Charleston, SC without transferring at least 3 times.


Travel Information
Compare bus and train for Greenville, NC to Charleston, SC
Omio recommends booking the train as it is the most popular option from Greenville, NC to Charleston, SC among Omio's users. If you are prioritising price take the train with prices starting from €74. For those with little time consider booking a train which can get you there in 5h 23m. The ticket price range depends on the travel mode: a train costs an average of €74, and a bus costs an average of €132.
Distance: 244 miles (394 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€132 Average price | €86 Average price Cheapest |
21h 50m Average total duration 21h 20m Onboard + 30m Additional time* | 5h 53m Average total duration Fastest 5h 23m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Live departures
Greenville, NC to Charleston, SC bus times
The table below shows live departures for Greenville, NC to Charleston, SC buses for today, Thursday, November 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:20 PM Greenville, NC | 21h21 | 3:41 PM Charleston, SC | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Greenville, NC to Charleston, SC by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 07
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Nov 13
Journey information
Overview: Bus from Greenville, NC to Charleston, SC
Distance 244 miles (394 km) |
Average bus duration 21h 20m |
Cheapest ticket price $162 (€132) |
Buses per day 2 |
Fastest bus 21h 18m |
First bus 09:15 |
Last bus 13:55 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Greenville, NC to Charleston, SC start from as low as $162 (€132) if booked well in advance.
- Standard Fares: Typically, trains cost $162 (€132) depending on the train type and class.
Bus providers: Greyhound from Greenville, NC to Charleston, SCYou can travel by bus between Greenville, NC to Charleston, SC with Greyhound for as low as $91 (€74). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Greenville, NC to Charleston, SC
Find answers to the most common questions about traveling from Greenville, NC to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Greenville, NC to Charleston, SC, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
Most popular bus connections from Greenville, NC
More options for your journey from Greenville, NC to Charleston, SC
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