Travel Information
Compare train for Charleston, SC to Greenville, NC
Omio recommends booking the train as it is the most popular option from Charleston, SC to Greenville, NC among Omio's users. If you are prioritising price take the train with prices starting from $100. For those with little time consider booking a train which can get you there in 4h 23m. The ticket price range depends on the travel mode: a train costs an average of $100, and a train costs an average of $100.
Distance: 244 miles (394 km)
Compare train with
Most popular Train | Driving |
|---|---|
$112 Average price Cheapest | $57 Average price (fuel + tolls) |
4h 53m Average total duration Fastest 4h 23m Onboard + 30m Additional time* | 4h 54m Average total duration (door-to-door) |
![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options |
Charleston, SC to Greenville, NC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:50PM | Arrival Time 08:55AM | Duration 20h05 | Departure days Sat | Cheapest price $99 |
Compare prices and tickets Charleston, SC to Greenville, NC by train
Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Charleston, SC to Greenville, NC
Take a bus from Charleston, SC to Greenville, NC and enjoy the approximately 244 miles (394 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 09:15, the last at 13:55.
Distance 244 miles (394 km) |
Buses per day 1 |
First bus 9:15 AM |
Last bus 1:55 PM |
Cheapest Month Oct |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 35 days |
FAQs: Bus from Charleston, SC to Greenville, NC
Find answers to the most common questions about traveling from Charleston, SC to Greenville, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, NC, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Charleston, SC to Greenville, NC
Most Charleston, SC to Greenville, NC buses use the Charleston, Gaynor Avenue (Greyhound Bus Station) to Greenville, S Pitt St (Butterfield Transportation Center) station pair. Use this guide to compare Charleston, SC and Greenville, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Charleston, SC station do buses to Greenville, NC leave from?
Getting to Charleston, Gaynor Avenue (Greyhound Bus Station) from Charleston city centre
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Charleston, Gaynor Avenue (Greyhound Bus Station) bus station facilities and services
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Parking, taxis and toilets
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
Which Greenville, NC station do buses from Charleston, SC arrive at?
Getting to Greenville, S Pitt St (Butterfield Transportation Center) from Greenville city centre
Greenville, S Pitt St (Butterfield Transportation Center) bus station facilities and services
Greenville, S Pitt St (Butterfield Transportation Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free wifi available in waiting areas. ATMs are available at Greenville, S Pitt St (Butterfield Transportation Center).
Tickets and information
Ticket office support is available at Greenville, S Pitt St (Butterfield Transportation Center).
Parking, taxis and toilets
Available at Greenville, S Pitt St (Butterfield Transportation Center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Greenville, S Pitt St (Butterfield Transportation Center): Wheelchair accessible entrances and seating areas.
Most popular bus connections from Charleston, SC
More options for your journey from Charleston, SC to Greenville, NC
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