- Must visit
Greenville County Museum of Art
Major art museum in downtown Greenville with Southern art, traveling exhibitions, and a strong permanent collection.
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Travel Information
Compare bus for Charleston, SC to Greenville, NC
Omio recommends booking the bus as it is the most popular option from Charleston, SC to Greenville, NC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $107 For those with little time, consider booking a bus, which has an average total journey time of 10h 3m. Average ticket prices depend on the travel mode: a bus costs an average of $107, while a bus costs an average of $107.
Distance: 244 miles (394 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
$107 Average price Cheapest | $57 Average price (fuel + tolls) |
10h 3m Average total duration Fastest 9h 33m Onboard + 30m Additional time* | 4h 54m Average total duration (door-to-door) |
 Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
The cheapest way to travel from Charleston, SC to Greenville, NC is a bus with an average price of $107.
The fastest way to travel from Charleston, SC to Greenville, NC is by bus with an average journey time of 9h 33m.
Yes, you can take a bus between Charleston, SC and Greenville, NC.
We recommend using the bus as it is the most popular way to get from Charleston, SC to Greenville, NC among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $107 compared to roughly $57 in fuel and tolls — a saving of about $-50.17. The journey takes 9h 33m versus 4h 54m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Charleston, SC to Greenville, NC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 10:00AM | Arrival Time 06:40PM | Duration 8h40 | Departure days Fri | Cheapest price $61 |
Compare prices and tickets Charleston, SC to Greenville, NC by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Charleston, SC to Greenville, NC buses with Omio?
Greyhound as well as FlixBus offer buses services from Charleston, SC to Greenville, NC.
Omio is an official ticket reseller for all your travel options from Charleston, SC to Greenville, NC.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Charleston, SC to Greenville, NC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Charleston, SC to Greenville, NC.
Journey information
Overview: Bus from Charleston, SC to Greenville, NC
USAUSA
Buses from Charleston, SC to Greenville, NC run on average 1 times per day, taking around 9h 33m. Cheap bus tickets for this journey start at $54 if you book in advance.
The earliest bus runs at 09:15, the last at 13:55. The fastest bus covers the 244 miles (394 km) distance in 8h 20m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 244 miles (394 km) |
Average bus duration 9h 33m |
Cheapest ticket price $54 |
Buses per day 1 |
Fastest bus 8h 20m |
First bus 9:15 AM |
Last bus 1:55 PM |
Cheapest Month Aug |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 5 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus, Greyhound from Charleston, SC to Greenville, NCYou can travel by bus between Charleston, SC to Greenville, NC with FlixBus, Greyhound for as low as $54. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
9h 45m
Cheapest FlixBus Price
$98
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
8h 20m
Cheapest Greyhound Price
$54
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Greenville, NC
Things to do in Greenville, NC
Discover the best of Greenville, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville, NC trip today.
- Recommended
The Children's Museum of the Upstate
Children's museum with hands-on science, art, and play exhibits designed for families and young learners.
- Recommended
Upcountry History Museum
Railway museum featuring historic cabooses and locomotives, with seasonal excursions on the Greenville and Western line.
- Must visit
Falls Park on the Reedy
Signature downtown park with waterfalls, gardens, lawns, and river walks centered around the Reedy River.
- Must visit
Main Street
Tree-lined pedestrian-friendly main street with shops, public art, and easy access to downtown attractions.
- Recommended
Prisma Health Swamp Rabbit Trail
Long multi-use greenway for walking and cycling that links parks, public art, and several Greenville districts.
FAQs: Bus from Charleston, SC to Greenville, NC
Find answers to the most common questions about traveling from Charleston, SC to Greenville, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, NC, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Charleston, SC to Greenville, NC can start from as little as $54 when you book in advance. The average bus ticket price for Charleston, SC to Greenville, NC is $107 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Charleston, SC to Greenville, NC is 8h 20m to travel the 244 miles (394 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Charleston, SC to Greenville, NC leaves at 9:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Charleston, SC to Greenville, NC leaves at 1:55 PM.
There are 1 buses a day from Charleston, SC to Greenville, NC which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Charleston, SC to Greenville, NC, you can count on Greyhound, FlixBus for the best way to get you to Greenville, NC. You can also check all possible bus companies who offer a service between Charleston, SC and Greenville, NC and compare the amenities they offer before buying a bus ticket.
Passengers board the bus most frequently from Charleston, Gaynor Avenue (Greyhound Bus Station), SC, which is located around 7 miles (12 km) away from the city centre, and they get off the bus at Greenville, S Pitt St (Butterfield Transportation Center), NC, located 0 away from the city centre.
A trip to Greenville, NC from Charleston, SC is worth doing but not as a day trip with a journey time of 8h 20m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Charleston, SC to Greenville, NC is August.
Yes, you can take a bus between Charleston, SC and Greenville, NC.
Yes, there are bathrooms on board the bus from Charleston, SC to Greenville, NC for bus company Greyhound, FlixBus.
Yes, the following accessibility options are available when taking the bus from Charleston, SC to Greenville, NC:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Charleston, SC to Greenville, NC depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Charleston, SC to Greenville, NC.
Yes, the following luggage options are included when booking a bus ticket from Charleston, SC to Greenville, NC:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Charleston, SC to Greenville, NC:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Charleston, SC to Greenville, NC. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Charleston, SC to Greenville, NC with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Charleston, SC to Greenville, NC with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Charleston, SC to Greenville, NC with the following bus company: Greyhound, FlixBus.
Since neither Charleston, SC nor Greenville, NC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Charleston, SC to Greenville, NC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Greenville, NC, travelers should be cautious of petty theft and vehicle break-ins, especially in crowded or tourist-heavy areas. Common scams include overcharging by unofficial taxi or ride-share services and unsolicited offers for tours or accommodations. It’s advisable to use licensed transportation, keep valuables secure, and remain aware of surroundings, particularly at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Charleston, SC to Greenville, NC
Most Charleston, SC to Greenville, NC buses use the Charleston, Gaynor Avenue (Greyhound Bus Station) to Greenville, S Pitt St (Butterfield Transportation Center) station pair. Use this guide to compare Charleston, SC and Greenville, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Charleston
Arrival bus stations in Greenville
Which Charleston, SC station do buses to Greenville, NC leave from?
Buses from Charleston, SC to Greenville, NC leave from Charleston, Gaynor Avenue (Greyhound Bus Station). The station is 8 miles (13 km) from Charleston, SC city centre at 4565 Gaynor Ave, Charleston, SC 29405, USA.
Charleston, Gaynor Avenue (Greyhound Bus Station)4565 Gaynor Ave, Charleston, SC 29405, USA
City-centre transport
Getting to Charleston, Gaynor Avenue (Greyhound Bus Station) from Charleston city centre
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Bus10 · 32m · every ~4 min
10 · 41m · every ~4 min
Charleston, Gaynor Avenue (Greyhound Bus Station) bus station facilities and services
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Parking, taxis and toilets
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
Which Greenville, NC station do buses from Charleston, SC arrive at?
Buses from Charleston, SC to Greenville, NC arrive at Greenville, S Pitt St (Butterfield Transportation Center). Greenville, S Pitt St (Butterfield Transportation Center) is 0 miles (1 km) from Greenville, NC city centre.
Greenville, S Pitt St (Butterfield Transportation Center)600 S Pitt St, Greenville, NC 27834, USA
City-centre transport
Getting to Greenville, S Pitt St (Butterfield Transportation Center) from Greenville city centre
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Greenville, S Pitt St (Butterfield Transportation Center) bus station facilities and services
Greenville, S Pitt St (Butterfield Transportation Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free wifi available in waiting areas. ATMs are available at Greenville, S Pitt St (Butterfield Transportation Center).
Tickets and information
Ticket office support is available at Greenville, S Pitt St (Butterfield Transportation Center).
Parking, taxis and toilets
Available at Greenville, S Pitt St (Butterfield Transportation Center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Greenville, S Pitt St (Butterfield Transportation Center): Wheelchair accessible entrances and seating areas.
Most popular bus connections from Charleston, SC
More options for your journey from Charleston, SC to Greenville, NC
Here are some other resources that might have the information you need
Most popular buses to and from Greenville, NC and Charleston, SC
Most popular bus connections to Greenville, NC
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