The cheapest and fastest buses from Frankfurt am Main to Brno
Cheapest price
$47
Average price
$63
Fastest journey
12 h 55 m
Average duration
13 h 4 m
Buses per day
3
Distance
579 km
The best way to find a cheap bus ticket from Frankfurt am Main to Brno is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main to Brno will cost around $63 if you buy it on the day, but the cheapest tickets can be found for only $47.
Of the 3 buses that leave Frankfurt am Main for Brno on Sat, Mar 21, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Mar 21 the direct buses cover the 579 km distance in an average of 13 h 4 m but if you time it right, some buses will get you there in just 12 h 55 m .
On Sat, Mar 21 the slowest buses will take 13 h 22 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Travel Information
Compare bus and train for Frankfurt am Main to Brno
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Brno among Omio's users. If you are prioritising price take the bus with prices starting from $38. For those with little time consider booking a train which can get you there in 8h 45m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $38, and a train costs an average of $43.
Distance: 359 miles (579 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
$61 Average price Cheapest | $140 Average price |
10h 17m Average total duration 9h 47m Onboard + 30m Additional time* | 9h 15m Average total duration Fastest 8h 45m Onboard + 30m Additional time* |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Frankfurt am Main to Brno Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:05AM | Arrival Time 01:40PM | Duration 12h35 | Departure days Fri | Cheapest price $101 |
Operator FlixBus | Departure Time 01:15AM | Arrival Time 01:40PM | Duration 12h25 | Departure days Mon, Thu, Fri | Cheapest price $52 |
Operator FlixBus | Departure Time 01:50AM | Arrival Time 01:40PM | Duration 11h50 | Departure days Mon, Thu, Fri | Cheapest price $43 |
Operator FlixBus | Departure Time 04:20AM | Arrival Time 08:00PM | Duration 15h40 | Departure days Mon, Thu, Fri | Cheapest price $55 |
Operator FlixBus | Departure Time 04:50AM | Arrival Time 08:00PM | Duration 15h10 | Departure days Thu | Cheapest price $52 |
Operator FlixBus | Departure Time 06:05AM | Arrival Time 06:05PM | Duration 12h00 | Departure days Mon, Thu | Cheapest price $43 |
Operator FlixBus | Departure Time 06:10AM | Arrival Time 06:45PM | Duration 12h35 | Departure days Fri | Cheapest price $62 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 10:05PM | Duration 13h05 | Departure days Mon, Thu, Fri | Cheapest price $48 |
Operator FlixBus | Departure Time 09:55AM | Arrival Time 11:55PM | Duration 14h00 | Departure days Mon | Cheapest price $52 |
Operator FlixBus | Departure Time 09:58AM | Arrival Time 01:05AM | Duration 15h07 | Departure days Mon, Thu, Fri | Cheapest price $68 |
Operator FlixBus | Departure Time 10:25AM | Arrival Time 11:55PM | Duration 13h30 | Departure days Mon | Cheapest price $43 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 01:05AM | Duration 14h25 | Departure days Mon, Thu, Fri | Cheapest price $52 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 01:05AM | Duration 13h50 | Departure days Mon, Thu, Fri | Cheapest price $43 |
Operator FlixBus | Departure Time 11:58AM | Arrival Time 01:55AM | Duration 13h57 | Departure days Fri | Cheapest price $65 |
Operator FlixBus | Departure Time 01:00PM | Arrival Time 01:55AM | Duration 12h55 | Departure days Thu | Cheapest price $65 |
Operator FlixBus | Departure Time 01:40PM | Arrival Time 05:50AM | Duration 16h10 | Departure days Thu | Cheapest price $69 |
Operator FlixBus | Departure Time 01:58PM | Arrival Time 04:10AM | Duration 14h12 | Departure days Mon | Cheapest price $78 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 05:50AM | Duration 15h05 | Departure days Mon, Thu | Cheapest price $42 |
Operator FlixBus | Departure Time 02:50PM | Arrival Time 01:55AM | Duration 11h05 | Departure days Fri | Cheapest price $59 |
Operator FlixBus | Departure Time 03:58PM | Arrival Time 04:10AM | Duration 12h12 | Departure days Thu, Fri | Cheapest price $58 |
Operator FlixBus | Departure Time 04:20PM | Arrival Time 08:25AM | Duration 16h05 | Departure days Mon | Cheapest price $43 |
Operator FlixBus | Departure Time 05:58PM | Arrival Time 05:20AM | Duration 11h22 | Departure days Fri | Cheapest price $70 |
Operator FlixBus | Departure Time 06:05PM | Arrival Time 08:55AM | Duration 14h50 | Departure days Mon, Thu, Fri | Cheapest price $52 |
Operator FlixBus | Departure Time 06:35PM | Arrival Time 08:55AM | Duration 14h20 | Departure days Mon, Thu, Fri | Cheapest price $43 |
Operator Regiojet | Departure Time 10:30PM | Arrival Time 09:30AM | Duration 11h00 | Departure days Mon, Thu, Fri | Cheapest price $46 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 11:00AM | Duration 11h30 | Departure days Mon, Thu, Fri | Cheapest price $52 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 11:20AM | Duration 11h21 | Departure days Mon, Thu, Fri | Cheapest price $42 |
Live departures
Frankfurt am Main to Brno bus times
The table below shows live departures for Frankfurt am Main to Brno buses for today, Friday, March 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixTrain+ FlixBus · FlixBus | 10:58 AM Frankfurt South station | 13h57 | 12:55 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 2 transfers | |
FlixBus · FlixBus | 1:50 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 11h05 | 12:55 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixTrain+ FlixBus | 2:58 PM Frankfurt South station | 12h12 | 3:10 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixTrain+ FlixBus | 4:58 PM Frankfurt South station | 11h22 | 4:20 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixBus · FlixBus | 5:05 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 14h50 | 7:55 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixBus · FlixBus | 5:35 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 14h20 | 7:55 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
(Amsterdam -> Prague) · (Prague -> Vienna) | 9:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 11h00 | 8:30 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixBus · FlixBus | 10:30 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 11h30 | 10:00 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixBus · FlixBus | 10:59 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 11h01 | 10:00 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
| Saturday, March 21 | |||||
![]() | 8:58 AM Frankfurt am Main | 13h22 | 10:20 PM Brno | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Frankfurt am Main to Brno by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Mar 27
Why should you book Frankfurt am Main to Brno buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Infobus to find the best option for your trip from Frankfurt am Main to Brno.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and train to ensure you get the best deal for traveling from Frankfurt am Main to Brno.
Why book with Omio over Wanderu, Trainline or Busbud?
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Frankfurt am Main to Brno.
Journey information
Overview: Bus from Frankfurt am Main to Brno
Buses from Frankfurt am Main to Brno run on average 18 times per day, taking around 9h 47m. Cheap bus tickets for this journey start at $38 (€31) if you book in advance.
The earliest bus runs at 00:25, the last at 23:45. The fastest bus covers the 359 miles (579 km) distance in 10h 30m.
Distance 359 miles (579 km) |
Average bus duration 9h 47m |
Cheapest ticket price $38 (€31) |
Buses per day 18 |
Fastest bus 10h 30m |
First bus 00:25 |
Last bus 23:45 |
Cheapest month Jul |
Cheapest day Wed |
High season Jul - Sep |
Low season Oct - Dec |
Busiest day Thu |
Least busy day Fri |
Best day to book ahead 42 days |
Bus providers: FlixBus, Infobus, BlaBlaCar from Frankfurt am Main to BrnoYou can travel by bus between Frankfurt am Main to Brno with FlixBus, Infobus, BlaBlaCar for as low as $38 (€31). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
BlaBlaCar
FAQs: Bus from Frankfurt am Main to Brno
Find answers to the most common questions about traveling from Frankfurt am Main to Brno by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brno, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Špilberk Castle, a historic fortress offering panoramic views of the city and housing a museum
- Cathedral of St. Peter and Paul, a striking Gothic cathedral known for its twin spires and rich history
- Villa Tugendhat, a UNESCO World Heritage site showcasing modernist architecture by Mies van der Rohe
- Brno Underground, a network of historical tunnels and cellars beneath the city center
- Moravian Museum, the second-largest museum in the Czech Republic, featuring diverse exhibits on natural history and culture.
- Moravian Karst, a natural reserve with stunning caves and hiking trails located just outside the city
- Brno Technical Museum, an interactive museum featuring exhibits on the history of technology and industry in the region
- Mendel Museum, dedicated to the life and work of Gregor Mendel, the father of genetics
- Lužánky Park, the oldest public park in Brno, perfect for a leisurely stroll or a picnic
- Brno Zoo, offering a fun and educational experience with a variety of animal species.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Frankfurt am Main to Brno
- 00:00-23:59
- Free Wi-Fi
- McDonald's (in the station)
- Hausmann's (in the station).
- Available outside the terminal at designated taxi stands.
- Elevators, ramps, assistance
- Available in the station.
- Bus: 61, 62, 77 Train: S8, S9
- 00:00-23:59
- Free Wi-Fi
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 40, 61, 67 Tram: 1, 2, 4, 8, 9, 10, 12 Train: S2, S3, S6
Most popular bus connections from Frankfurt am Main
More options for your journey from Frankfurt am Main to Brno
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