The cheapest and fastest buses from Rome to Brno
Cheapest price
$91
Average price
$100
Fastest journey
19 h 20 m
Average duration
21 h 46 m
Buses per day
5
Distance
873 km
The best way to find a cheap bus ticket from Rome to Brno is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Brno will cost around $100 if you buy it on the day, but the cheapest tickets can be found for only $91.
It's difficult to get from Rome to Brno without transferring at least once.
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FlixBus · FlixBusTravel Information
Compare train and bus for Rome to Brno
Omio recommends booking the bus as it is the most popular option from Rome to Brno among Omio's users. If you are prioritising price take the bus with prices starting from $55. For those with little time consider booking a train which can get you there in 12h 40m. The ticket price range depends on the travel mode: a bus costs an average of $55, and a train costs an average of $216.
Distance: 542 miles (873 km)
Compare bus with
Most popular Bus | Train |
|---|---|
$111 Average price Cheapest | $232 Average price |
18h 17m Average total duration 17h 47m Onboard + 30m Additional time* | 13h 10m Average total duration Fastest 12h 40m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Rome to Brno Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 08:30AM | Arrival Time 08:25AM | Duration 23h55 | Departure days Tue, Wed | Cheapest price $92 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 08:25AM | Duration 20h05 | Departure days Mon, Fri, Sat, Sun | Cheapest price $96 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 08:25AM | Duration 19h40 | Departure days Mon, Fri, Sat, Sun | Cheapest price $91 |
Operator Regiojet | Departure Time 01:00PM | Arrival Time 06:40AM | Duration 17h40 | Departure days Wed | Cheapest price $69 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 12:25PM | Duration 23h20 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $106 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 12:25PM | Duration 19h20 | Departure days Mon, Tue, Wed, Fri, Sat | Cheapest price $107 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 01:20AM | Duration 26h25 | Departure days Wed, Fri, Sat, Sun | Cheapest price $101 |
Live departures
Rome to Brno bus times
The table below shows live departures for Rome to Brno buses for today, Friday, March 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 11:20 AM Roma, Autostazione Tiburtina | 20h05 | 7:25 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixBus · FlixBus | 11:45 AM Roma, Autostazione (Metro Anagnina) | 19h40 | 7:25 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 12:05 PM Roma, Autostazione (Metro Anagnina) | 23h20 | 11:25 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 2 transfers | |
FlixBus · FlixBus | 4:05 PM Roma, Autostazione Tiburtina | 19h20 | 11:25 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixBus · FlixBus | 9:55 PM Roma, Autostazione Tiburtina | 26h25 | 12:20 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer |
Find all the dates and times for this journey
Compare prices and tickets Rome to Brno by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 21
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Why should you book Rome to Brno buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Rome to Brno.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Rome to Brno.
Journey information
Overview: Bus from Rome to Brno
Buses from Rome to Brno run on average 6 times per day, taking around 17h 47m. Cheap bus tickets for this journey start at $55 (€45) if you book in advance.
The earliest bus runs at 01:35, the last at 23:50. The fastest bus covers the 542 miles (873 km) distance in 17h 40m.
Distance 542 miles (873 km) |
Average bus duration 17h 47m |
Cheapest ticket price $55 (€45) |
Buses per day 6 |
Fastest bus 17h 40m |
First bus 01:35 |
Last bus 23:50 |
Bus providers: FlixBus from Rome to BrnoYou can travel by bus between Rome to Brno with FlixBus for as low as $55 (€45). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Rome to Brno
Find answers to the most common questions about traveling from Rome to Brno by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brno, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Špilberk Castle, a historic fortress offering panoramic views of the city and housing a museum
- Cathedral of St. Peter and Paul, a striking Gothic cathedral known for its twin spires and rich history
- Villa Tugendhat, a UNESCO World Heritage site showcasing modernist architecture by Mies van der Rohe
- Brno Underground, a network of historical tunnels and cellars beneath the city center
- Moravian Museum, the second-largest museum in the Czech Republic, featuring diverse exhibits on natural history and culture.
- Moravian Karst, a natural reserve with stunning caves and hiking trails located just outside the city
- Brno Technical Museum, an interactive museum featuring exhibits on the history of technology and industry in the region
- Mendel Museum, dedicated to the life and work of Gregor Mendel, the father of genetics
- Lužánky Park, the oldest public park in Brno, perfect for a leisurely stroll or a picnic
- Brno Zoo, offering a fun and educational experience with a variety of animal species.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Rome to Brno
- 00:00-23:59
- Free Wi-Fi
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 40, 61, 67 Tram: 1, 2, 4, 8, 9, 10, 12 Train: S2, S3, S6
More options for your journey from Rome to Brno
Here are some other resources that might have the information you need

