- Must visit
Villa Tugendhat
Modernist villa by Mies van der Rohe, listed by UNESCO. An essential architecture visit for its groundbreaking open-plan interior.
The best way to find a cheap bus ticket from Rome to Brno is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Brno will cost around $112 if you buy it on the day, but the cheapest tickets can be found for only $93.
It's difficult to get from Rome to Brno without transferring at least once.
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Buses from Rome to Brno run on average 5 times per day, taking around 18h 28m. Cheap bus tickets for this journey start at $68 but you can travel from only $8 by train.
The earliest bus runs at 01:35, the last at 23:50. The fastest bus covers the 542 miles (873 km) distance in 16h 50m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Rome to Brno.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:20PM | Arrival Time 08:25AM | Duration 20h05 | Departure days Everyday | Cheapest price $91 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 08:25AM | Duration 19h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $101 |
Operator RegioJet a.s. | Departure Time 01:00PM | Arrival Time 06:40AM | Duration 17h40 | Departure days Wed | Cheapest price $77 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 12:25PM | Duration 23h20 | Departure days Everyday | Cheapest price $95 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 12:25PM | Duration 19h20 | Departure days Everyday | Cheapest price $93 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 01:20AM | Duration 26h25 | Departure days Wed | Cheapest price $97 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 11:55PM | Duration 24h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $111 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 04:05AM | Duration 28h30 | Departure days Thu | Cheapest price $122 |
The table below shows live departures for Rome to Brno buses for today, Sunday, November 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 20h05 | 8:25 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixBus · FlixBus | 12:45 PM Roma, Autostazione (Metro Anagnina) | 19h40 | 8:25 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 23h20 | 12:25 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 2 transfers | |
FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 19h20 | 12:25 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:05 PM Roma, Autostazione Tiburtina | 20h55 | 8:00 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 2 transfers |
Find all the dates and times for this journey
Buses from Rome to Brno with FlixBus. Overnight buses available on this route with FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Brno — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brno trip today.
Modernist villa by Mies van der Rohe, listed by UNESCO. An essential architecture visit for its groundbreaking open-plan interior.
Brno’s city museum inside Špilberk Castle, covering local history, art, and prison heritage in a dramatic hilltop complex.
Major regional museum with natural science, history, and temporary exhibitions. A strong choice for understanding Moravia in context.
Brno’s main central square, lined with historic facades, events, and public art. A practical meeting point and key place to feel the city.
Historic market square with colorful townhouses, the Parnas fountain, and regular produce and festive markets. One of Brno’s liveliest areas.
Prominent hill around the cathedral, with calm lanes and viewpoints over the old town. Ideal for short walks and classic Brno panoramas.
Brno's classic bun filled with whipped cream. It is a beloved local pastry tied to the city's café culture and everyday sweet eating.
Pork schnitzel with potato salad is a Czech staple widely loved in Brno for family meals, pubs, and festive gatherings.
Roast beef in creamy root vegetable sauce with bread dumplings. A cornerstone Czech dish commonly served in traditional Brno restaurants.
Fine dining restaurant with modern Czech and Central European tasting menus in an elegant, contemporary setting.
Well-known restaurant and wine bar focused on Moravian ingredients, seasonal cooking, and a polished but relaxed atmosphere.
Traditional Brno restaurant by Špilberk Castle known for Czech dishes, local beer, and a historic cellar atmosphere.
More affordable than Prague and many Western European cities. Dining and transit are low-cost, while central hotels are moderate in peak periods.
Service is often not included. Round up or tip 5-10% in restaurants. Round up small taxi fares and leave small change in cafes if service is good.
Official public transport app
Brno, Benešova - Grandhotel (Hlavní nádraží) -> Náměstí Svobody, Brno
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Brno.
Find answers to the most common questions about traveling from Rome to Brno by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brno, this guide helps you travel smarter and with confidence.

Most Rome to Brno buses use the Roma, Autostazione Tiburtina to Brno, Benešova - Grandhotel (Hlavní nádraží) station pair. Use this guide to compare Rome and Brno bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Brno, Benešova - Grandhotel (Hlavní nádraží) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, and Ticket Office.
Free Wi-Fi. ATMs are located inside the station.
Ticket office support is available at Brno, Benešova - Grandhotel (Hlavní nádraží).
Available at Brno, Benešova - Grandhotel (Hlavní nádraží): Parking, Taxis, WC.
Accessibility facilities are available at Brno, Benešova - Grandhotel (Hlavní nádraží): Elevators, ramps.
Check bus stations information for Rome and Brno, including where buses depart and arrive on this route.