Travel Information
Compare train and bus for Frankfurt am Main to Brno
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Brno among Omio's users. If you are prioritising price take the bus with prices starting from $38. For those with little time consider booking a train which can get you there in 8h 56m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of $38, and a train costs an average of $50.
Distance: 359 miles (579 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$131 Average price | $55 Average price Cheapest | $156 Average price (fuel + tolls) |
9h 26m Average total duration Fastest 8h 56m Onboard + 30m Additional time* | 10h 16m Average total duration 9h 46m Onboard + 30m Additional time* | 7h 24m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Frankfurt am Main to Brno:
A bus is $76 (€61) less than a train for this route with tickets for a train from Frankfurt am Main to Brno costing on average $131 (€105).
Other travel options to Brno take longer:
Bus takes on average 9h 46m.
Travel optionsfrom Frankfurt am Main to Brno
How to get from Frankfurt am Main to Brno by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Brno is by taking a bus because it’s the best combination of price and speed.
(Amsterdam -> Prague) · (Prague -> Vienna)10:30 PM11h00Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)9:30 AMBrno, Benešova - Grandhotel (Hlavní nádraží)$671One-way1 transfer
Cheapest
(Amsterdam -> Prague) · (Prague -> Vienna)10:30 PM11h00Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)9:30 AMBrno, Benešova - Grandhotel (Hlavní nádraží)$671One-way1 transfer
Fastest
ICE 1221 · EC 202 · rj 2748:21 AM9h20Frankfurt (Main) Hbf5:41 PMBrno hlavní nádraží$3731One-way2 transfers
Other options
ICE 527 · 3465 · RJ 257+
3578:57 AM10h16Frankfurt (Main) Hbf7:13 PMBrno hlavní nádraží$1891One-way3 transfers
ICE 527 · R 3465 · R 3565 · EC 3578:57 AM10h16Frankfurt (Main) Hbf7:13 PMBrno hlavní nádraží$2261One-way4 transfers
ICE 529 · RJX 67 · EC 100 · RJ 2729:57 AM9h44Frankfurt (Main) Hbf7:41 PMBrno hlavní nádraží$2381One-way3 transfers
FlixBus+
FlixTrain5:58 PM11h22Frankfurt South station5:20 AMBrno, Benešova - Grandhotel (Hlavní nádraží)$711One-way1 transfer
FlixBus · FlixBus11:59 PM11h56Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)11:55 AMBrno, Benešova - Grandhotel (Hlavní nádraží)$801One-way1 transfer
FlixBus · FlixBus6:35 PM14h20Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)8:55 AMBrno, Benešova - Grandhotel (Hlavní nádraží)$881One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Frankfurt am Main to Brno
Travel to Brno easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Brno.

This is compared to other travel options from Frankfurt am Main to Brno:
A bus is $76 (€61) less than a train for this route with tickets for a train from Frankfurt am Main to Brno costing on average $131 (€105).
Other travel options to Brno take longer:
Bus takes on average 9h 46m.
- Around 18 buses per day.
- Around 11 trains per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Brno as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Brno hlavní nádraží.
- Buses mostly depart from Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) and arrive in Brno, Benešova - Grandhotel (Hlavní nádraží).
- Travel with FlixBus, Infobus, BlaBlaCar to go to Brno by bus.
- Travel with Deutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH, Deutsche Bahn Intercity (DB IC) to go to Brno by train.
- 0 direct buses per day with Infobus, BlaBlaCar.
Travelling from Frankfurt am Main to Brno: related information
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