Travel Information
Compare train and bus for Frankfurt am Main to Brno
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Brno among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €60 For those with little time, consider booking a flight, which has an average total journey time of 3h 20m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of €60, while a flight costs an average of €182.
Distance: 359 miles (579 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
€150 Average price | €60 Average price Cheapest | €182 Average price | €126 Average price (fuel + tolls) |
9h 51m Average total duration 9h 21m Onboard + 30m Additional time* | 12h 21m Average total duration 11h 51m Onboard + 30m Additional time* | 3h 20m Average total duration Fastest 1h 20m Onboard + 2h 0m Additional time* | 7h 24m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | - CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Frankfurt am Main to Brno
Compare the available ways to get from Frankfurt am Main to Brno, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Frankfurt am Main to Brno:
A bus is €91 less than a train for this route with tickets for a train from Frankfurt am Main to Brno costing on average €150.
A bus is €123 less than a flight for this route with tickets for a flight from Frankfurt am Main to Brno costing on average €182.
Other travel options to Brno take longer:
Train takes on average 9h 51m.
Bus takes on average 12h 21m.
Tickets start at around €150 compared to roughly €126 in fuel and tolls — a saving of about -€23. The journey takes 9h 21m versus 7h 24m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Frankfurt am Main to Brno
How to get from Frankfurt am Main to Brno by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Brno is by taking a bus because it’s the best combination of price and speed.
(Amsterdam -> Prague) · (Prague -> Vienna)10:30 PM 11h00 Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) 9:30 AM Brno, Benešova - Grandhotel (Hlavní nádraží) €44 1 One-way 1 transfer
Cheapest
(Amsterdam -> Prague) · (Prague -> Vienna)10:30 PM 11h00 Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) 9:30 AM Brno, Benešova - Grandhotel (Hlavní nádraží) €44 1 One-way 1 transfer
Fastest
ICE 690 · IC 2441 · rj 17712:15 PM 9h58 Frankfurt (Main) Hbf 10:13 PM Brno hlavní nádraží €98 1 One-way 2 transfers
Other options
ICE 1557 · rj 10383 · rj 383 · EC 2839:19 AM 10h54 Frankfurt (Main) Hbf 8:13 PM Brno hlavní nádraží €54 1 One-way 3 transfers
ICE 1651 · rj 385 · rj 5771:19 PM 11h22 Frankfurt (Main) Hbf 12:41 AM Brno hlavní nádraží €62 1 One-way 2 transfers
ICE 994 · ICE 583 · 3565 · Bus RE258:20 AM 10h53 Frankfurt South station 7:13 PM Brno hlavní nádraží €117 1 One-way 5 transfers
FlixBus · FlixBus11:59 PM 11h56 Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) 11:55 AM Brno, Benešova - Grandhotel (Hlavní nádraží) €48 1 One-way 1 transfer
FlixBus · FlixBus1:50 AM 11h50 Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) 1:40 PM Brno, Benešova - Grandhotel (Hlavní nádraží) €52 1 One-way 1 transfer
FlixTrain+
FlixBus3:58 PM 12h12 Frankfurt South station 4:10 AM Brno, Benešova - Grandhotel (Hlavní nádraží) €52 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Frankfurt am Main to Brno
Travel to Brno easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Brno.

This is compared to other travel options from Frankfurt am Main to Brno:
A bus is €91 less than a train for this route with tickets for a train from Frankfurt am Main to Brno costing on average €150.
A bus is €123 less than a flight for this route with tickets for a flight from Frankfurt am Main to Brno costing on average €182.
Other travel options to Brno take longer:
Train takes on average 9h 51m.
Bus takes on average 12h 21m.
- Around 15 buses per day.
- Around 8 trains per day.
- Around 3 flights per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Brno as scheduled services by train and bus can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Vienna International Airport.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Brno hlavní nádraží.
- Buses mostly depart from Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) and arrive in Brno, Benešova - Grandhotel (Hlavní nádraží).
- Travel with České dráhy, Deutsche Bahn, alex-Länderbahn und Vogtlandbahn-GmbH, Leo Express to go to Brno by train.
- Travel with FlixBus, Infobus to go to Brno by bus.
- Travel with Condor Flugdienst to go to Brno by flight.
- 0 direct buses per day with Infobus.
- 3 direct flights per day with Condor Flugdienst.
Travelling from Frankfurt am Main to Brno: related information
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