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Compare train and bus for Frankfurt am Main to Brno
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Brno among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $79 For those with little time, consider booking a train, which has an average total journey time of 9h 39m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of $79, while a train costs an average of $202.
Distance: 359 miles (579 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$202 Average price | $79 Average price Cheapest | $152 Average price (fuel + tolls) |
9h 39m Average total duration Fastest 9h 9m Onboard + 30m Additional time* | 12h 26m Average total duration 11h 56m Onboard + 30m Additional time* | 7h 24m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Frankfurt am Main to Brno:
A bus is $123 (€102) less than a train for this route with tickets for a train from Frankfurt am Main to Brno costing on average $202 (€166).
Other travel options to Brno take longer:
Bus takes on average 12h 26m.
Tickets start at around $202 (€166) compared to roughly $152 (€125) in fuel and tolls — a saving of about $-49.81 (€-41.02). The journey takes 9h 9m versus 7h 24m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Frankfurt am Main to Brno
How to get from Frankfurt am Main to Brno by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Brno is by taking a bus because it’s the best combination of price and speed.
(Amsterdam -> Prague) · (Prague -> Vienna)10:30 PM11h00Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)9:30 AMBrno, Benešova - Grandhotel (Hlavní nádraží)$551One-way1 transfer
Cheapest
(Amsterdam -> Prague) · (Prague -> Vienna)10:30 PM11h00Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)9:30 AMBrno, Benešova - Grandhotel (Hlavní nádraží)$551One-way1 transfer
Fastest
ICE 692 · IC 2443 · RJ 383 · EC 28310:15 AM9h58Frankfurt (Main) Hbf8:13 PMBrno hlavní nádraží$1461One-way3 transfers
Other options
ICE 694 · IC 2445 · RJ 1758:15 AM9h59Frankfurt (Main) Hbf6:14 PMBrno hlavní nádraží$1461One-way2 transfers
ICE 774 · ICE 583 · 3565 · RJ 2578:46 AM10h27Frankfurt (Main) Hbf7:13 PMBrno hlavní nádraží$1591One-way4 transfers
ICE 1557 · RJ 383 · EC 2839:19 AM10h54Frankfurt (Main) Hbf8:13 PMBrno hlavní nádraží$1651One-way2 transfers
FlixBus · FlixBus4:20 PM12h55Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)5:15 AMBrno, Benešova - Grandhotel (Hlavní nádraží)$641One-way1 transfer
FlixBus · FlixBus6:35 PM14h20Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)8:55 AMBrno, Benešova - Grandhotel (Hlavní nádraží)$641One-way1 transfer
FlixBus · FlixBus11:15 AM12h05Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)11:20 PMBrno, Benešova - Grandhotel (Hlavní nádraží)$661One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Frankfurt am Main to Brno
Travel to Brno easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Brno.

This is compared to other travel options from Frankfurt am Main to Brno:
A bus is $123 (€102) less than a train for this route with tickets for a train from Frankfurt am Main to Brno costing on average $202 (€166).
Other travel options to Brno take longer:
Bus takes on average 12h 26m.
- Around 15 buses per day.
- Around 9 trains per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Brno as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Brno hlavní nádraží.
- Buses mostly depart from Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) and arrive in Brno, Benešova - Grandhotel (Hlavní nádraží).
- Travel with Leo Express, Deutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH to go to Brno by train.
- Travel with Infobus, FlixBus to go to Brno by bus.
- 0 direct buses per day with Infobus.
Travelling from Frankfurt am Main to Brno: related information
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