- Must visit
Villa Tugendhat
Modernist villa by Mies van der Rohe, listed by UNESCO. An essential architecture visit for its groundbreaking open-plan interior.
The best way to find a cheap bus ticket from Brussels to Brno is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brussels to Brno will cost around €87 if you buy it on the day, but the cheapest tickets can be found for only €71.
It's difficult to get from Brussels to Brno without transferring at least once.
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Buses from Brussels to Brno run on average 6 times per day, taking around 18h 56m. Cheap bus tickets for this journey start at €24 if you book in advance.
The earliest bus runs at 00:45, the last at 23:30. The fastest bus covers the 555 miles (894 km) distance in 17h 25m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Brussels to Brno.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:20AM | Arrival Time 01:05AM | Duration 23h45 | Departure days Thu, Fri, Sat, Sun | Cheapest price €69 |
Operator FlixBus | Departure Time 02:15AM | Arrival Time 03:10AM | Duration 24h55 | Departure days Tue | Cheapest price €71 |
Operator FlixBus | Departure Time 03:15AM | Arrival Time 01:05AM | Duration 21h50 | Departure days Sat, Sun | Cheapest price €89 |
Operator FlixBus | Departure Time 09:05AM | Arrival Time 12:40PM | Duration 27h35 | Departure days Tue | Cheapest price €51 |
Operator FlixBus | Departure Time 01:40PM | Arrival Time 12:40PM | Duration 23h00 | Departure days Mon | Cheapest price €51 |
Operator FlixBus | Departure Time 02:15PM | Arrival Time 09:20AM | Duration 19h05 | Departure days Mon | Cheapest price €89 |
Operator FlixBus | Departure Time 02:40PM | Arrival Time 01:40PM | Duration 23h00 | Departure days Tue, Wed | Cheapest price €61 |
Operator FlixBus | Departure Time 03:15PM | Arrival Time 10:20AM | Duration 19h05 | Departure days Mon, Tue, Wed | Cheapest price €51 |
Operator FlixBus | Departure Time 03:40PM | Arrival Time 02:40PM | Duration 23h00 | Departure days Thu, Fri, Sat, Sun | Cheapest price €70 |
Operator FlixBus | Departure Time 03:55PM | Arrival Time 02:05PM | Duration 22h10 | Departure days Fri, Sun | Cheapest price €71 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 11:20AM | Duration 19h05 | Departure days Thu, Fri, Sat, Sun | Cheapest price €72 |
Operator FlixBus | Departure Time 04:40PM | Arrival Time 01:40PM | Duration 21h00 | Departure days Thu, Sat, Sun | Cheapest price €83 |
Operator FlixBus | Departure Time 05:40PM | Arrival Time 05:10PM | Duration 23h30 | Departure days Thu, Fri, Sun | Cheapest price €79 |
Operator RegioJet a.s. | Departure Time 06:30PM | Arrival Time 09:30AM | Duration 15h00 | Departure days Thu, Sun | Cheapest price €61 |
Operator FlixBus | Departure Time 08:15PM | Arrival Time 07:25PM | Duration 23h10 | Departure days Thu, Fri | Cheapest price €75 |
Operator FlixBus | Departure Time 09:30PM | Arrival Time 05:05PM | Duration 19h35 | Departure days Mon | Cheapest price €67 |
Operator FlixBus | Departure Time 10:30PM | Arrival Time 05:10PM | Duration 18h40 | Departure days Sat, Sun | Cheapest price €90 |
Operator FlixBus | Departure Time 11:20PM | Arrival Time 09:20PM | Duration 22h00 | Departure days Mon | Cheapest price €65 |
Operator FlixBus | Departure Time 11:45PM | Arrival Time 10:55PM | Duration 23h10 | Departure days Tue | Cheapest price €86 |
The table below shows live departures for Brussels to Brno buses for tomorrow, Sunday, November 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 1:20 AM Brussels, Brussels South (Gare du Midi) | 22h00 | 11:20 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:15 AM Brussels, Brussels South (Gare du Midi) | 21h50 | 1:05 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:40 PM Brussels, Avenue des Magnolias (King Baudouin) | 23h00 | 2:40 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:55 PM Brussels, Gare Du Midi | 22h10 | 2:05 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 2 transfers | |
FlixBus · FlixBus | 4:15 PM Brussels, Brussels South (Gare du Midi) | 19h05 | 11:20 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixBus · FlixBus | 4:40 PM Brussels, Brussels South (Gare du Midi) | 21h00 | 1:40 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 5:40 PM Brussels, Brussels South (Gare du Midi) | 23h30 | 5:10 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 2 transfers | |
(London -> Prague) · (Prague -> Vienna) | 6:30 PM Brussels, Brussels South (Gare du Midi) | 15h00 | 9:30 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixBus · FlixBus | 10:30 PM Brussels, Brussels South (Gare du Midi) | 19h35 | 6:05 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Brussels to Brno with FlixBus. Overnight buses available on this route with FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Brno — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brno trip today.
Modernist villa by Mies van der Rohe, listed by UNESCO. An essential architecture visit for its groundbreaking open-plan interior.
Brno’s city museum inside Špilberk Castle, covering local history, art, and prison heritage in a dramatic hilltop complex.
Major regional museum with natural science, history, and temporary exhibitions. A strong choice for understanding Moravia in context.
Brno’s main central square, lined with historic facades, events, and public art. A practical meeting point and key place to feel the city.
Historic market square with colorful townhouses, the Parnas fountain, and regular produce and festive markets. One of Brno’s liveliest areas.
Prominent hill around the cathedral, with calm lanes and viewpoints over the old town. Ideal for short walks and classic Brno panoramas.
Brno's classic bun filled with whipped cream. It is a beloved local pastry tied to the city's café culture and everyday sweet eating.
Pork schnitzel with potato salad is a Czech staple widely loved in Brno for family meals, pubs, and festive gatherings.
Roast beef in creamy root vegetable sauce with bread dumplings. A cornerstone Czech dish commonly served in traditional Brno restaurants.
Fine dining restaurant with modern Czech and Central European tasting menus in an elegant, contemporary setting.
Well-known restaurant and wine bar focused on Moravian ingredients, seasonal cooking, and a polished but relaxed atmosphere.
Traditional Brno restaurant by Špilberk Castle known for Czech dishes, local beer, and a historic cellar atmosphere.
More affordable than Prague and many Western European cities. Dining and transit are low-cost, while central hotels are moderate in peak periods.
Service is often not included. Round up or tip 5-10% in restaurants. Round up small taxi fares and leave small change in cafes if service is good.
Official public transport app
Brno, Benešova - Grandhotel (Hlavní nádraží) -> Náměstí Svobody, Brno
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Brno.
Find answers to the most common questions about traveling from Brussels to Brno by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brno, this guide helps you travel smarter and with confidence.

Most Brussels to Brno buses use the Brussels, Brussels South (Gare du Midi) to Brno, Benešova - Grandhotel (Hlavní nádraží) station pair. Use this guide to compare Brussels and Brno bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Brussel, Avenue des Magnolias (Koning Boudewijn) is 5 km from Brussels city centre. Public transport options include:
Brussel, Avenue des Magnolias (Koning Boudewijn) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Brussel, Avenue des Magnolias (Koning Boudewijn). ATMs are available at Brussel, Avenue des Magnolias (Koning Boudewijn).
Ticket office support is available at Brussel, Avenue des Magnolias (Koning Boudewijn).
Available at Brussel, Avenue des Magnolias (Koning Boudewijn): Parking, Taxis, WC.
Accessibility facilities are available at Brussel, Avenue des Magnolias (Koning Boudewijn): Accessible for people with reduced mobility.
Brussels, Gare Du Midi is 1 km from Brussels city centre. Public transport options include:
Brussels, Gare Du Midi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Various dining options are nearby.
Wi-Fi is available at Brussels, Gare Du Midi. ATMs are available at Brussels, Gare Du Midi.
Ticket office support is available at Brussels, Gare Du Midi.
Available at Brussels, Gare Du Midi: Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Gare Du Midi: Station is accessible for individuals with disabilities.
Brno, Benešova - Grandhotel (Hlavní nádraží) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, and Ticket Office.
Free Wi-Fi. ATMs are located inside the station.
Ticket office support is available at Brno, Benešova - Grandhotel (Hlavní nádraží).
Available at Brno, Benešova - Grandhotel (Hlavní nádraží): Parking, Taxis, WC.
Accessibility facilities are available at Brno, Benešova - Grandhotel (Hlavní nádraží): Elevators, ramps.
Check bus stations information for Brussels and Brno, including where buses depart and arrive on this route.