- Must visit
Moravian Gallery in Brno
The Czech Republic’s second-largest art museum, spread across several historic buildings and known for design, modern art, and strong temporary exhibitions.
Cheapest price
$88
Average price
$94
Fastest journey
19 h 15 m
Average duration
20 h 15 m
Buses per day
9
Distance
962 km
The best way to find a cheap bus ticket from Lyon to Brno is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Brno will cost around $94 if you buy it on the day, but the cheapest tickets can be found for only $88.
It's difficult to get from Lyon to Brno without transferring at least once.
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
(Lyon -> Prague) · (Prague -> Brno)
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the bus as it is the most popular option from Lyon to Brno among Omio's users. If you are prioritising price take the bus with prices starting from $67. For those with little time consider booking a bus which can get you there in 18h 58m. The ticket price range depends on the travel mode: a bus costs an average of $67, and a train costs an average of $345.
Distance: 597 miles (962 km)
Most popular Bus | Train | Driving |
|---|---|---|
$87 Average price Cheapest | $351 Average price | $305 Average price (fuel + tolls) |
19h 28m Average total duration Fastest 18h 58m Onboard + 30m Additional time* | 21h 10m Average total duration 20h 40m Onboard + 30m Additional time* | 13h 5m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Lyon to Brno:
A bus is $264 (€216) less than a train for this route with tickets for a train from Lyon to Brno costing on average $351 (€287).
Other travel options to Brno take longer:
Train takes on average 20h 40m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:30AM | Arrival Time 11:55PM | Duration 20h25 | Departure days Sat | Cheapest price $90 |
Operator FlixBus | Departure Time 05:20AM | Arrival Time 01:55AM | Duration 20h35 | Departure days Sat | Cheapest price $90 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 06:45AM | Duration 21h45 | Departure days Sat | Cheapest price $88 |
Operator FlixBus | Departure Time 10:45AM | Arrival Time 08:25AM | Duration 21h40 | Departure days Sat | Cheapest price $88 |
Operator FlixBus | Departure Time 11:05AM | Arrival Time 07:45AM | Duration 20h40 | Departure days Sun | Cheapest price $97 |
Operator FlixBus | Departure Time 12:05PM | Arrival Time 08:45AM | Duration 20h40 | Departure days Mon, Wed | Cheapest price $67 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 09:45AM | Duration 20h40 | Departure days Sat | Cheapest price $103 |
Operator RegioJet a.s. | Departure Time 02:35PM | Arrival Time 10:55AM | Duration 20h20 | Departure days Sat | Cheapest price $101 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 12:20PM | Duration 19h05 | Departure days Fri | Cheapest price $132 |
Operator FlixBus | Departure Time 06:05PM | Arrival Time 01:20PM | Duration 19h15 | Departure days Sat | Cheapest price $102 |
Operator FlixBus | Departure Time 07:30PM | Arrival Time 05:25PM | Duration 21h55 | Departure days Fri, Sun | Cheapest price $89 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 09:20PM | Duration 25h20 | Departure days Mon, Sun | Cheapest price $101 |
Operator FlixBus | Departure Time 08:30PM | Arrival Time 06:25PM | Duration 21h55 | Departure days Tue, Sun | Cheapest price $69 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 10:20PM | Duration 25h20 | Departure days Mon, Thu, Sun | Cheapest price $69 |
Operator FlixBus | Departure Time 09:30PM | Arrival Time 07:25PM | Duration 21h55 | Departure days Sat | Cheapest price $88 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 10:05PM | Duration 24h05 | Departure days Sat | Cheapest price $98 |
The table below shows live departures for Lyon to Brno buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:15 PM Lyon | 19h05 | 12:20 PM Brno | 0 transfersDirect | |
![]() | 7:30 PM Lyon | 21h55 | 5:25 PM Brno | 0 transfersDirect | |
| Saturday, June 20 | |||||
FlixBus · FlixBus | 3:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 20h25 | 11:55 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Lyon to Brno run on average 6 times per day, taking around 18h 58m. Cheap bus tickets for this journey start at $67 (€55) if you book in advance.
The earliest bus runs at 01:20, the last at 23:30. The fastest bus covers the 597 miles (962 km) distance in 19h 5m.
Distance 597 miles (962 km) |
Average bus duration 18h 58m |
Cheapest ticket price $67 (€55) |
Buses per day 6 |
Fastest bus 19h 5m |
First bus 1:20 AM |
Last bus 11:30 PM |
Cheapest Month Sep |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Apr - Jun |
Best time to book 14 days |
Discover the best of Brno — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brno trip today.
The Czech Republic’s second-largest art museum, spread across several historic buildings and known for design, modern art, and strong temporary exhibitions.
A major regional museum with natural history, archaeology, and cultural collections, including exhibitions linked to Mendel and Moravian heritage.
A UNESCO-listed modernist masterpiece by Mies van der Rohe and one of Brno’s most famous cultural sites. Visits are by guided tour and usually require advance booking.
Brno’s main central square, surrounded by historic facades, shops, and landmarks, and a natural starting point for exploring the city.
The hill around the cathedral offers classic city views and one of Brno’s most atmospheric short walks.
A historic market square with daily local life, attractive architecture, and easy access to several important underground sites.
A classic Moravian dish of roasted pork served with cabbage and dumplings. It is a staple of local pubs and home cooking in Brno and across South Moravia.
Marinated beef sirloin in a creamy vegetable sauce, usually served with bread dumplings, lemon, and cranberries. It is one of the best-known festive Czech dishes.
A hearty sauerkraut soup often enriched with sausage, potatoes, and paprika. It is especially associated with Moravian farmhouse cooking and cold-weather meals.
An established upscale restaurant known for polished modern Czech and European cuisine, elegant service, and a refined dining room.
A respected restaurant and brewery near Špilberk, offering Czech classics, its own beer, and a stylish but approachable atmosphere.
A long-established Brno beer hall serving classic Czech dishes, Pilsner beer, and traditional pub food in a lively historic setting.
Generally cheaper than Prague. Dining and public transport are reasonable, while central hotels cost more in peak periods.
About 10% is standard in restaurants for good service; round up in cafés and taxis. Tell the server the total when paying by card or cash.
Official public transport app
Brno, Benešova - Grandhotel (Hlavní nádraží) -> Brno hlavní nádraží
Find answers to the most common questions about traveling from Lyon to Brno by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brno, this guide helps you travel smarter and with confidence.

Most Lyon to Brno buses use the Lyon, Gare Routière de Perrache to Brno, Benešova - Grandhotel (Hlavní nádraží) station pair, with some services arriving at Brno, ÚAN Zvonařka. Use this guide to compare Lyon and Brno bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, Gare Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Bistro Lyonnais (0.2 km), Fast Food Express (0.3 km).
Free Wi-Fi. ATMs are located near the main entrance and in the shopping area.
Ticket office support is available at Lyon, Gare Perrache.
Available at Lyon, Gare Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Perrache: Elevators, ramps.
Brno, Benešova - Grandhotel (Hlavní nádraží) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, and Ticket Office.
Free Wi-Fi. ATMs are located inside the station.
Ticket office support is available at Brno, Benešova - Grandhotel (Hlavní nádraží).
Available at Brno, Benešova - Grandhotel (Hlavní nádraží): Parking, Taxis, WC.
Accessibility facilities are available at Brno, Benešova - Grandhotel (Hlavní nádraží): Elevators, ramps.
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