- Must visit
Villa Tugendhat
Modernist villa by Mies van der Rohe, listed by UNESCO. An essential architecture visit for its groundbreaking open-plan interior.
The best way to find a cheap bus ticket from Lyon to Brno is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Brno will cost around $88 if you buy it on the day, but the cheapest tickets can be found for only $78.
On Mon, Nov 02, we found 3 buses from Lyon to Brno, including 3 direct services.
On Mon, Nov 02 the direct buses cover the 962 km distance in an average of 1 d 18 m but if you time it right, some buses will get you there in just 22 h 15 m .
On Mon, Nov 02 the slowest buses will take 1 d 1 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Lyon to Brno run on average 7 times per day, taking around 19h 42m. Cheap bus tickets for this journey start at $62 if you book in advance.
The earliest bus runs at 01:20, the last at 23:30. The fastest bus covers the 597 miles (962 km) distance in 14h 30m.
Distance 597 miles (962 km) |
Average bus duration 19h 42m |
Cheapest ticket price $62 |
Buses per day 7 |
Fastest bus 14h 30m |
First bus 1:20 AM |
Last bus 11:30 PM |
Cheapest Month Jun |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Best time to book 14 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Lyon to Brno.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:10AM | Arrival Time 01:20AM | Duration 22h10 | Departure days Sun | Cheapest price $122 |
Operator FlixBus | Departure Time 03:30AM | Arrival Time 11:55PM | Duration 20h25 | Departure days Fri | Cheapest price $97 |
Operator FlixBus | Departure Time 05:20AM | Arrival Time 01:55AM | Duration 20h35 | Departure days Fri, Sun | Cheapest price $98 |
Operator FlixBus | Departure Time 10:45AM | Arrival Time 08:25AM | Duration 21h40 | Departure days Fri | Cheapest price $95 |
Operator FlixBus | Departure Time 11:05AM | Arrival Time 07:45AM | Duration 20h40 | Departure days Sat | Cheapest price $100 |
Operator FlixBus | Departure Time 11:30AM | Arrival Time 08:25AM | Duration 20h55 | Departure days Sun | Cheapest price $102 |
Operator FlixBus | Departure Time 12:05PM | Arrival Time 10:20AM | Duration 22h15 | Departure days Mon, Wed | Cheapest price $66 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 09:45AM | Duration 20h40 | Departure days Fri, Sun | Cheapest price $97 |
Operator FlixBus | Departure Time 06:05PM | Arrival Time 01:20PM | Duration 19h15 | Departure days Fri, Sun | Cheapest price $94 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 09:20PM | Duration 25h20 | Departure days Mon | Cheapest price $103 |
Operator FlixBus | Departure Time 08:30PM | Arrival Time 06:25PM | Duration 21h55 | Departure days Tue | Cheapest price $67 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 10:20PM | Duration 25h20 | Departure days Mon, Thu, Sat | Cheapest price $68 |
Operator FlixBus | Departure Time 09:30PM | Arrival Time 07:25PM | Duration 21h55 | Departure days Fri, Sun | Cheapest price $94 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 11:20PM | Duration 25h20 | Departure days Fri, Sun | Cheapest price $96 |
The table below shows live departures for Lyon to Brno buses for today, Sunday, November 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 11:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 20h55 | 8:25 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixBus · FlixBus | 1:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 20h40 | 9:45 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixBus · FlixBus | 6:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 19h15 | 1:20 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixBus · FlixBus | 9:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 21h55 | 7:25 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
FlixBus · FlixBus | 10:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 25h20 | 11:20 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer |
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Brno — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brno trip today.
Modernist villa by Mies van der Rohe, listed by UNESCO. An essential architecture visit for its groundbreaking open-plan interior.
Brno’s city museum inside Špilberk Castle, covering local history, art, and prison heritage in a dramatic hilltop complex.
Major regional museum with natural science, history, and temporary exhibitions. A strong choice for understanding Moravia in context.
Brno’s main central square, lined with historic facades, events, and public art. A practical meeting point and key place to feel the city.
Historic market square with colorful townhouses, the Parnas fountain, and regular produce and festive markets. One of Brno’s liveliest areas.
Prominent hill around the cathedral, with calm lanes and viewpoints over the old town. Ideal for short walks and classic Brno panoramas.
Brno's classic bun filled with whipped cream. It is a beloved local pastry tied to the city's café culture and everyday sweet eating.
Pork schnitzel with potato salad is a Czech staple widely loved in Brno for family meals, pubs, and festive gatherings.
Roast beef in creamy root vegetable sauce with bread dumplings. A cornerstone Czech dish commonly served in traditional Brno restaurants.
Fine dining restaurant with modern Czech and Central European tasting menus in an elegant, contemporary setting.
Well-known restaurant and wine bar focused on Moravian ingredients, seasonal cooking, and a polished but relaxed atmosphere.
Traditional Brno restaurant by Špilberk Castle known for Czech dishes, local beer, and a historic cellar atmosphere.
More affordable than Prague and many Western European cities. Dining and transit are low-cost, while central hotels are moderate in peak periods.
Service is often not included. Round up or tip 5-10% in restaurants. Round up small taxi fares and leave small change in cafes if service is good.
Official public transport app
Brno, Benešova - Grandhotel (Hlavní nádraží) -> Náměstí Svobody, Brno
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Brno.
Find answers to the most common questions about traveling from Lyon to Brno by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brno, this guide helps you travel smarter and with confidence.

Most Lyon to Brno buses use the Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) to Brno, Benešova - Grandhotel (Hlavní nádraží) station pair, with some services arriving at Brno, ÚAN Zvonařka. Use this guide to compare Lyon and Brno bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, St Exupéry Aéroport is 2 km from Lyon city centre. Public transport options include:
Lyon, St Exupéry Aéroport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, St Exupéry Aéroport. ATMs are available at Lyon, St Exupéry Aéroport.
Ticket office support is available at Lyon, St Exupéry Aéroport.
Available at Lyon, St Exupéry Aéroport: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, St Exupéry Aéroport: Access ramps and services available.
Brno, Benešova - Grandhotel (Hlavní nádraží) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, and Ticket Office.
Free Wi-Fi. ATMs are located inside the station.
Ticket office support is available at Brno, Benešova - Grandhotel (Hlavní nádraží).
Available at Brno, Benešova - Grandhotel (Hlavní nádraží): Parking, Taxis, WC.
Accessibility facilities are available at Brno, Benešova - Grandhotel (Hlavní nádraží): Elevators, ramps.
Check bus stations information for Lyon and Brno, including where buses depart and arrive on this route.
Here are some other resources that might have the information you need