Lyon to Brno bus with FlixBus

Fri, Sep 18
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2,000+ travel companies
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The cheapest and fastest buses from Lyon to Brno

Showing times, prices and bookable tickets for Sep 18

Cheapest price on Sep 18

$109

Average ticket price on Sep 18

$120

Fastest journey on Sep 18

19 h 5 m

Average journey duration on Sep 18

20 h 30 m

Buses on Sep 18

2

Distance

962 km

Cheap tickets

The best way to find a cheap bus ticket from Lyon to Brno is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Lyon to Brno will cost around $120 if you buy it on the day, but the cheapest tickets can be found for only $109.

Fast buses

On Fri, Sep 18, we found 2 buses from Lyon to Brno, including 2 direct services.

On Fri, Sep 18 the direct buses cover the 962 km distance in an average of 20 h 30 m but if you time it right, some buses will get you there in just 19 h 5 m .

On Fri, Sep 18 the slowest buses will take 21 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • FlixBus
    7:30 PM21h55
    Lyon
    5:25 PMBrno
    $1091One-way
    0 transfers
  • FlixBus
    5:15 PM19h05
    Lyon
    12:20 PMBrno
    $1321One-way
    0 transfers

Travel Information

Compare train and bus for Lyon to Brno

Omio recommends booking the bus as it is the most popular option from Lyon to Brno among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $111 For those with little time, consider booking a bus, which has an average total journey time of 20h 4m. Average ticket prices depend on the travel mode: a bus costs an average of $111, while a bus costs an average of $111.

Distance: 597 miles (962 km)

Compare bus with

Most popular
Bus
Train
Driving

$111

Average price

Cheapest

$308

Average price

(fuel + tolls)

20h 4m

Average total duration

Fastest

19h 34m

Onboard

+

30m

Additional time*

13h 5m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Lyon to Brno is a bus with an average price of $111.
The fastest way to travel from Lyon to Brno is by bus with an average journey time of 19h 34m.
It's helpful to compare your options as there are 2 ways to travel between Lyon and Brno including taking a train and bus.
We recommend using the bus as it is the most popular way to get from Lyon to Brno among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $111 compared to roughly $308 in fuel and tolls — a saving of about $197. The journey takes 19h 34m versus 13h 5m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Lyon to Brno Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
03:10AM
Arrival Time
01:20AM
Duration
22h10
Departure days
Thu
Cheapest price
$80
Operator
FlixBus
Departure Time
10:45AM
Arrival Time
08:25AM
Duration
21h40
Departure days
Thu
Cheapest price
$118
Operator
FlixBus
Departure Time
11:05AM
Arrival Time
07:45AM
Duration
20h40
Departure days
Sat, Sun
Cheapest price
$97
Operator
FlixBus
Departure Time
12:05PM
Arrival Time
08:45AM
Duration
20h40
Departure days
Mon, Wed
Cheapest price
$67
Operator
FlixBus
Departure Time
01:05PM
Arrival Time
09:45AM
Duration
20h40
Departure days
Thu
Cheapest price
$80
Operator
FlixBus
Departure Time
05:15PM
Arrival Time
12:20PM
Duration
19h05
Departure days
Fri
Cheapest price
$132
Operator
FlixBus
Departure Time
06:05PM
Arrival Time
01:40PM
Duration
19h35
Departure days
Thu
Cheapest price
$81
Operator
FlixBus
Departure Time
07:30PM
Arrival Time
05:25PM
Duration
21h55
Departure days
Fri, Sun
Cheapest price
$89
Operator
FlixBus
Departure Time
08:00PM
Arrival Time
09:20PM
Duration
25h20
Departure days
Mon, Sun
Cheapest price
$101
Operator
FlixBus
Departure Time
08:30PM
Arrival Time
06:25PM
Duration
21h55
Departure days
Tue, Sun
Cheapest price
$69
Operator
FlixBus
Departure Time
09:00PM
Arrival Time
10:20PM
Duration
25h20
Departure days
Mon, Sat, Sun
Cheapest price
$70
Operator
FlixBus
Departure Time
09:30PM
Arrival Time
07:25PM
Duration
21h55
Departure days
Thu
Cheapest price
$79
Operator
FlixBus
Departure Time
10:00PM
Arrival Time
11:20PM
Duration
25h20
Departure days
Thu
Cheapest price
$79

Live departures

Lyon to Brno bus times

The table below shows live departures for Lyon to Brno buses for today, Thursday, September 17. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBusFlixBus · FlixBus10:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
21h40
8:25 AM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
FlixBusFlixBus · FlixBus1:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
20h40
9:45 AM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
FlixBusFlixBus · FlixBus6:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
19h35
1:40 PM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
FlixBusFlixBus · FlixBus9:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
21h55
7:25 PM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
FlixBusFlixBus · FlixBus10:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
25h20
11:20 PM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer

Find all the dates and times for this journey

Compare prices and tickets Lyon to Brno by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Sep 18
Sat
Sep 19
Sun
Sep 20
Mon
Sep 21
Tue
Sep 22
Wed
Sep 23
Thu
Sep 24

Why should you book Lyon to Brno buses with Omio?

FlixBus operates all buses services from Lyon to Brno.
Omio is an official ticket reseller for all your travel options from Lyon to Brno.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Lyon to Brno.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Lyon to Brno.

Journey information

Overview: Bus from Lyon to Brno

FranceFrance
CzechiaCzechia
Icon of bus

Buses from Lyon to Brno run on average 7 times per day, taking around 19h 34m. Cheap bus tickets for this journey start at $63 if you book in advance.

The earliest bus runs at 01:20, the last at 23:30. The fastest bus covers the 597 miles (962 km) distance in 14h 30m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
597 miles (962 km)
Average bus duration
19h 34m
Cheapest ticket price
$63
Buses per day
7
Fastest bus
14h 30m
First bus
1:20 AM
Last bus
11:30 PM
Cheapest Month
Sep
Cheapest Day
Tue
High Season
Jul - Sep
Low Season
Jan - Mar
Best time to book
14 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, AMI-Tour from Lyon to BrnoYou can travel by bus between Lyon to Brno with FlixBus, AMI-Tour for as low as $63. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
17h 50m
Cheapest FlixBus Price
$63
FlixBus frequency
8 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

AMI-Tour

Luggage & cancellation policy
Average AMI-Tour Duration
14h 30m
Cheapest AMI-Tour Price
$159
AMI-Tour frequency
1 a day

Complete guide to Brno

Things to do in Brno

Discover the best of Brno — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brno trip today.

  • Must visit

Villa Tugendhat

Modernist villa by Mies van der Rohe, listed by UNESCO. An essential architecture visit for its groundbreaking open-plan interior.

  • Recommended

Museum of the City of Brno

Brno’s city museum inside Špilberk Castle, covering local history, art, and prison heritage in a dramatic hilltop complex.

  • Recommended

Moravian Museum

Major regional museum with natural science, history, and temporary exhibitions. A strong choice for understanding Moravia in context.

Czech koruna (Kč)

More affordable than Prague and many Western European cities. Dining and transit are low-cost, while central hotels are moderate in peak periods.

Average meal costs

Budget
180-250 Kč for fast food or lunch menu.
Mid-range
300-500 Kč per person for a restaurant meal.
Fine dining
1,200 Kč+ per person for upscale restaurants.
Coffee
55-75 Kč for cappuccino.

Tipping culture

Service is often not included. Round up or tip 5-10% in restaurants. Round up small taxi fares and leave small change in cafes if service is good.

FAQs: Bus from Lyon to Brno

Find answers to the most common questions about traveling from Lyon to Brno by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brno, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Lyon to Brno can start from as little as $63 when you book in advance. The average bus ticket price for Lyon to Brno is $111 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Lyon to Brno is 14h 30m to travel the 597 miles (962 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Lyon to Brno leaves at 1:20 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Lyon to Brno leaves at 11:30 PM.
There are 7 buses a day from Lyon to Brno which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Lyon to Brno, you can count on FlixBus for the best way to get you to Brno. You can also check all possible bus companies who offer a service between Lyon and Brno and compare the amenities they offer before buying a bus ticket.
When departing from Lyon , you have various bus station options to start your journey from including Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland), Lyon, Perrache Bus Station, Lyon, St Exupéry Aéroport, Lyon, Lyon, Gare Perrache . When arriving in Brno , you can end your journey in bus stations like Brno, Benešova - Grandhotel (Hlavní nádraží), Brno, ÚAN Zvonařka .Passengers board the bus most frequently from Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland), which is located around 1 miles (2 km) away from the city centre, and they get off the bus at Brno, Benešova - Grandhotel (Hlavní nádraží), located 0 away from the city centre.
A trip to Brno from Lyon is worth doing but not as a day trip with a journey time of 14h 30m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Lyon to Brno is September.
It's helpful to compare your options as there are 2 ways to travel between Lyon and Brno including taking a train and bus.
Yes, there are bathrooms on board the bus from Lyon to Brno for bus company FlixBus.
Yes, the following accessibility options are available when taking the bus from Lyon to Brno:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Some of the most interesting sights to explore in Brno are:
  • Špilberk Castle, a historic fortress offering panoramic views of the city and housing a museum
  • Cathedral of St. Peter and Paul, a striking Gothic cathedral known for its twin spires and rich history
  • Villa Tugendhat, a UNESCO World Heritage site showcasing modernist architecture by Mies van der Rohe
  • Brno Underground, a network of historical tunnels and cellars beneath the city center
  • Moravian Museum, the second-largest museum in the Czech Republic, featuring diverse exhibits on natural history and culture.
The best things to do in Brno include:
  • Moravian Karst, a natural reserve with stunning caves and hiking trails located just outside the city
  • Brno Technical Museum, an interactive museum featuring exhibits on the history of technology and industry in the region
  • Mendel Museum, dedicated to the life and work of Gregor Mendel, the father of genetics
  • Lužánky Park, the oldest public park in Brno, perfect for a leisurely stroll or a picnic
  • Brno Zoo, offering a fun and educational experience with a variety of animal species.
Whether you can cancel your bus ticket from Lyon to Brno depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Lyon to Brno.
Yes, the following luggage options are included when booking a bus ticket from Lyon to Brno:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Lyon to Brno:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Lyon to Brno. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Lyon to Brno with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Lyon to Brno with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Lyon to Brno with the following bus company: FlixBus.
Since both Lyon and Brno are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the bus as it is the most popular way to get from Lyon to Brno among Omio's users.
The currency used in Czechia is the Czech koruna (CZK). While many places accept card payments, cash is still widely used, especially in smaller shops and markets, so travelers should carry some cash but can also use cards conveniently in most urban areas.
In Brno, travelers should be cautious of pickpocketing, especially in crowded areas like public transport and popular tourist spots. Avoid unlicensed taxi services to prevent overcharging. Be wary of distraction scams near major attractions and keep an eye on personal belongings in busy markets or events. Overall, standard urban safety precautions apply.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Lyon to Brno

Most Lyon to Brno buses use the Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) to Brno, Benešova - Grandhotel (Hlavní nádraží) station pair, with some services arriving at Brno, ÚAN Zvonařka. Use this guide to compare Lyon and Brno bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Lyon
Arrival bus stations in Brno

Which Lyon station do buses to Brno leave from?

Buses from Lyon to Brno leave from Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). The station is 1 miles (3 km) from Lyon city centre at 52 Av. Tony Garnier, 69007 Lyon, France.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)52 Av. Tony Garnier, 69007 Lyon, FranceWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) from Lyon city centre

Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:

BusN734 · 15m · $1

Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) bus station facilities and services

Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).

Tickets and information

Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).

Parking, taxis and toilets

Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.

Lyon, Gare Routière de Perrache13 Cours de Verdun, 69002 Lyon, FranceWifiParkingDiningATMTaxisAccessibilityWCTicket Office
City-centre transport

Getting to Lyon, Gare Routière de Perrache from Lyon city centre

Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:

TrainTer · 5m · $1 · every ~5 min

Lyon, Gare Routière de Perrache bus station facilities and services

Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.

Food and drink

Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).

Wi-Fi and ATMs

Free Wi-Fi. ATMs are located near the main entrance.

Tickets and information

Ticket office support is available at Lyon, Gare Routière de Perrache.

Parking, taxis and toilets

Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.

Lyon, St Exupéry AéroportLyon St Exupéry Aéroport, 69125 Colombier-Saugnieu, FranceWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Lyon, St Exupéry Aéroport from Lyon city centre

Lyon, St Exupéry Aéroport is 2 km from Lyon city centre. Public transport options include:

TrainRx · 29m · $20 · every ~8 min
BusS766, 776, 787, N760, N1759, 1776, 1624, N746, 1779, S1736, 1606, 1787, 1676 · 38m · $2 · every ~1 min

Lyon, St Exupéry Aéroport bus station facilities and services

Lyon, St Exupéry Aéroport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Lyon, St Exupéry Aéroport. ATMs are available at Lyon, St Exupéry Aéroport.

Tickets and information

Ticket office support is available at Lyon, St Exupéry Aéroport.

Parking, taxis and toilets

Available at Lyon, St Exupéry Aéroport: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Lyon, St Exupéry Aéroport: Access ramps and services available.

More options for your journey from Lyon to Brno

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