The cheapest and fastest buses from Frankfurt am Main Airport to Lyon
Cheapest price
$38
Average price
$58
Fastest journey
9 h 35 m
Average duration
9 h 50 m
Buses per day
2
Distance
553 km
The best way to find a cheap bus ticket from Frankfurt am Main Airport to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main Airport to Lyon will cost around $58 if you buy it on the day, but the cheapest tickets can be found for only $38.
Of the 2 buses that leave Frankfurt am Main Airport for Lyon on Tue, Mar 03, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Mar 03 the direct buses cover the 553 km distance in an average of 9 h 50 m but if you time it right, some buses will get you there in just 9 h 35 m .
On Tue, Mar 03 the slowest buses will take 10 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare train, bus, and flight for Frankfurt am Main Airport to Lyon
Omio recommends booking the bus as it is the most popular option from Frankfurt am Main Airport to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $38. For those with little time consider booking a flight which can get you there in 2h 14m. The ticket price range depends on the travel mode: a bus costs an average of $38, and a flight costs an average of $161.
Distance: 343 miles (553 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$59 Average price Cheapest | $135 Average price | $283 Average price |
10h 28m Average total duration 9h 58m Onboard + 30m Additional time* | 6h 24m Average total duration 5h 54m Onboard + 30m Additional time* | 5h 14m Average total duration Fastest 2h 14m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Live departures
Frankfurt am Main Airport to Lyon bus times
The table below shows live departures for Frankfurt am Main Airport to Lyon buses for today, Monday, March 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:00 PM Frankfurt am Main Airport | 10h05 | 4:05 AM Lyon | 0 transfersDirect | |
![]() | 10:05 PM Frankfurt am Main Airport | 11h25 | 9:30 AM Lyon | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Frankfurt am Main Airport to Lyon by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 03
Mar 04
Mar 05
Mar 06
Mar 07
Mar 08
Mar 09
Why should you book Frankfurt am Main Airport to Lyon buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus or Infobus to find the best option for your trip from Frankfurt am Main Airport to Lyon.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Frankfurt am Main Airport to Lyon.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus or Infobus to find the best option for your trip from Frankfurt am Main Airport to Lyon.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Frankfurt am Main Airport to Lyon.
Journey information
Overview: Bus from Frankfurt am Main Airport to Lyon
Buses from Frankfurt am Main Airport to Lyon run on average 8 times per day, taking around 9h 58m. Cheap bus tickets for this journey start at $38 (€30) if you book in advance.
There are 2 buses per day. The earliest bus runs at 00:05, the last at 22:05. The fastest bus covers the 343 miles (553 km) distance in 9h 35m.
Distance 343 miles (553 km) |
Average bus duration 9h 58m |
Cheapest ticket price $38 (€30) |
Buses per day 8 |
Direct buses 2 |
Fastest bus 9h 35m |
First bus 00:05 |
Last bus 22:05 |
Bus providers: FlixBus, BlaBlaCar Bus, Infobus, BlaBlaCar from Frankfurt am Main Airport to LyonYou can travel by bus between Frankfurt am Main Airport to Lyon with FlixBus, BlaBlaCar Bus, Infobus, BlaBlaCar for as low as $38 (€30). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
BlaBlaCar Bus
BlaBlaCar
FAQs: Bus from Frankfurt am Main Airport to Lyon
Find answers to the most common questions about traveling from Frankfurt am Main Airport to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Basilica of Notre-Dame de Fourvière, a stunning 19th-century basilica offering panoramic views of the city
- Vieux Lyon, a UNESCO World Heritage site known for its Renaissance architecture and narrow cobblestone streets
- Parc de la Tête d'Or, a large urban park featuring a zoo, botanical garden, and lake
- Musée des Confluences, a modern science and anthropology museum with innovative exhibits
- Place Bellecour, one of Europe's largest open squares, ideal for shopping and dining.
- Les Halles de Lyon Paul Bocuse, a renowned indoor market offering gourmet food and local specialties
- Take a river cruise on the Rhône and Saône for a unique view of the city
- Explore the traboules, secret passageways in Vieux Lyon
- Attend a performance at the Opéra de Lyon, known for its diverse program
- Visit the Institut Lumière, dedicated to the history of cinema.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Infobus
- 10€ per additional bag.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Frankfurt am Main Airport to Lyon
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Bistro Lyonnais (0.2 km)
- Fast Food Express (0.3 km).
- Available outside the main entrance.
- Elevators, ramps
- Available on the concourse.
- Bus: C21, C22, S1 Metro: A Train: TER
Most popular bus connections from Frankfurt am Main Airport
More options for your journey from Frankfurt am Main Airport to Lyon
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