- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Cheapest price
$41
Average price
$63
Fastest journey
10 h 10 m
Average duration
11 h 14 m
Buses per day
4
Distance
553 km
The best way to find a cheap bus ticket from Frankfurt am Main Airport to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main Airport to Lyon will cost around $63 if you buy it on the day, but the cheapest tickets can be found for only $41.
Of the 4 buses that leave Frankfurt am Main Airport for Lyon on Fri, Jul 17, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jul 17 the direct buses cover the 553 km distance in an average of 11 h 14 m but if you time it right, some buses will get you there in just 10 h 10 m .
On Fri, Jul 17 the slowest buses will take 13 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.








Omio recommends booking the bus as it is the most popular option from Frankfurt am Main Airport to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $34. For those with little time consider booking a flight which can get you there in 2h 12m. The ticket price range depends on the travel mode: a bus costs an average of $34, and a flight costs an average of $166.
Distance: 343 miles (553 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$57 Average price Cheapest | $156 Average price | $295 Average price | $178 Average price (fuel + tolls) |
10h 27m Average total duration 9h 57m Onboard + 30m Additional time* | 6h 24m Average total duration 5h 54m Onboard + 30m Additional time* | 5h 12m Average total duration Fastest 2h 12m Onboard + 3h 0m Additional time* | 6h 30m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Frankfurt am Main Airport to Lyon:
A bus is $99 (€81) less than a train for this route with tickets for a train from Frankfurt am Main Airport to Lyon costing on average $156 (€128).
A bus is $239 (€195) less than a flight for this route with tickets for a flight from Frankfurt am Main Airport to Lyon costing on average $295 (€242).
Other travel options to Lyon take longer:
Train takes on average 5h 54m.
Bus takes on average 9h 57m.
Tickets start at around $57 (€47) compared to roughly $178 (€145) in fuel and tolls — a saving of about $121 (€99). The journey takes 9h 57m versus 6h 30m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar Bus, Infobus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:05AM | Arrival Time 03:25PM | Duration 15h20 | Departure days Mon, Tue | Cheapest price $44 |
Operator FlixBus | Departure Time 04:55AM | Arrival Time 07:35PM | Duration 14h40 | Departure days Sat | Cheapest price $69 |
Operator BlaBlaCar Bus | Departure Time 07:30AM | Arrival Time 06:45PM | Duration 11h15 | Departure days Wed | Cheapest price $53 |
Operator Alsa | Departure Time 07:30AM | Arrival Time 06:40PM | Duration 11h10 | Departure days Fri | Cheapest price $61 |
Operator BlaBlaCar Bus | Departure Time 08:30AM | Arrival Time 07:45PM | Duration 11h15 | Departure days Wed | Cheapest price $40 |
Operator FlixBus | Departure Time 08:55AM | Arrival Time 09:15PM | Duration 12h20 | Departure days Thu | Cheapest price $122 |
Operator BlaBlaCar Bus | Departure Time 11:25AM | Arrival Time 03:05AM | Duration 15h40 | Departure days Mon | Cheapest price $63 |
Operator FlixBus | Departure Time 03:00PM | Arrival Time 03:35AM | Duration 12h35 | Departure days Sat | Cheapest price $74 |
Operator FlixBus | Departure Time 03:50PM | Arrival Time 02:45AM | Duration 10h55 | Departure days Mon | Cheapest price $62 |
Operator BlaBlaCar Bus | Departure Time 05:00PM | Arrival Time 03:10AM | Duration 10h10 | Departure days Mon, Fri, Sat, Sun | Cheapest price $39 |
Operator FlixBus | Departure Time 05:30PM | Arrival Time 07:45AM | Duration 14h15 | Departure days Sat | Cheapest price $93 |
Operator BlaBlaCar Bus | Departure Time 06:00PM | Arrival Time 04:10AM | Duration 10h10 | Departure days Thu, Fri, Sat, Sun | Cheapest price $40 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 04:05AM | Duration 9h35 | Departure days Tue, Wed | Cheapest price $41 |
Operator FlixBus | Departure Time 07:30PM | Arrival Time 11:30AM | Duration 16h00 | Departure days Wed | Cheapest price $60 |
Operator FlixBus | Departure Time 10:05PM | Arrival Time 09:30AM | Duration 11h25 | Departure days Fri, Sat, Sun | Cheapest price $49 |
The table below shows live departures for Frankfurt am Main Airport to Lyon buses for today, Thursday, July 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:55 AM Frankfurt am Main Airport | 12h20 | 9:15 PM Lyon | 0 transfersDirect | |
![]() | 6:00 PM Frankfurt am Main Airport | 10h10 | 4:10 AM Lyon | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Frankfurt am Main Airport to Lyon run on average 8 times per day, taking around 9h 57m. Cheap bus tickets for this journey start at $34 (€28) if you book in advance.
There are 2 buses per day. The earliest bus runs at 00:05, the last at 22:05. The fastest bus covers the 343 miles (553 km) distance in 9h 35m.
Distance 343 miles (553 km) |
Average bus duration 9h 57m |
Cheapest ticket price $34 (€28) |
Buses per day 8 |
Direct buses 2 |
Fastest bus 9h 35m |
First bus 12:05 AM |
Last bus 10:05 PM |
Cheapest Month Sep |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Mon |
Least Busy Day Tue |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Museum of cinema miniatures and film props in Vieux Lyon. Popular for detailed sets, special-effects history, and family-friendly exhibits.
Excellent free natural history and ethnography museum with fossils, animals, and global cultures. A strong local favorite, especially for families.
Renaissance quarter with cobbled lanes, traboules, courtyards, and major monuments. Essential for atmosphere, history, and walking exploration.
Central peninsula between the Rhône and Saône, packed with elegant streets, squares, shopping, and many of Lyon’s classic city views.
Historic silk-workers’ hill district with stairways, murals, markets, and hidden passageways. Great for local character and city panoramas.
Pike dumplings in a rich crayfish sauce. A Lyon classic from traditional bouchons, prized for its delicate fish texture and luxurious sauce.
Crisp salad of frisée, bacon lardons, croutons, and a poached egg. A staple Lyonnaise bistro dish that reflects the city's hearty cooking style.
Slow-cooked onions with vinegar, often served warm or chilled. This old Lyonnais side dish is traditional in bouchons and pairs well with charcuterie.
Refined dining by Paul Bocuse, known for polished French cuisine and iconic Lyon dishes in an elegant, historic dining room.
Well-known traditional bouchon in Vieux Lyon, praised for generous Lyonnais specialties and a lively old-city atmosphere.
Historic bouchon near Place Bellecour serving quenelles, salade lyonnaise, and classic regional fare in a warm traditional setting.
Moderate for Western Europe: hotels and dining are mid-priced, while public transport is good value for visitors.
Service is usually included. Round up or leave 5-10% for great restaurant service. Round up taxi fares; small change is fine in cafes.
Find answers to the most common questions about traveling from Frankfurt am Main Airport to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

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