- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.







Cheapest price
$49
Average price
$67
Fastest journey
5h 0m
Average duration
7h 53m
Buses per day
7
Distance
418 km
Omio recommends booking the train as it is the most popular option from Frankfurt am Main Airport to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $15. For those with little time consider booking a flight which can get you there in 1h 36m. The ticket price range depends on the travel mode: a bus costs an average of $15, and a flight costs an average of $164.
Distance: 259 miles (417 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$38 Average price Cheapest | $110 Average price | $225 Average price | $112 Average price (fuel + tolls) |
9h 3m Average total duration 8h 33m Onboard + 30m Additional time* | 8h 7m Average total duration 7h 37m Onboard + 30m Additional time* | 4h 36m Average total duration Fastest 1h 36m Onboard + 3h 0m Additional time* | 5h 1m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Frankfurt am Main Airport to Prague:
A bus is $73 (€60) less than a train for this route with tickets for a train from Frankfurt am Main Airport to Prague costing on average $110 (€91).
A bus is $188 (€154) less than a flight for this route with tickets for a flight from Frankfurt am Main Airport to Prague costing on average $225 (€185).
Other travel options to Prague take longer:
Train takes on average 7h 37m.
Bus takes on average 8h 33m.
Tickets start at around $38 (€31) compared to roughly $112 (€92) in fuel and tolls — a saving of about $74 (€61). The journey takes 8h 33m versus 5h 1m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar, KLR, Infobus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:15AM | Arrival Time 09:20AM | Duration 8h05 | Departure days Everyday | Cheapest price $43 |
Operator FlixBus | Departure Time 04:20AM | Arrival Time 01:30PM | Duration 9h10 | Departure days Everyday | Cheapest price $43 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 07:35PM | Duration 8h55 | Departure days Everyday | Cheapest price $39 |
Operator BlaBlaCar | Departure Time 12:00PM | Arrival Time 05:00PM | Duration 5h00 | Departure days Fri | Cheapest price $50 |
Operator FlixBus | Departure Time 02:15PM | Arrival Time 10:55PM | Duration 8h40 | Departure days Sat, Sun | Cheapest price $73 |
Operator RegioJet a.s. | Departure Time 10:00PM | Arrival Time 04:48AM | Duration 6h48 | Departure days Everyday | Cheapest price $43 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 08:55AM | Duration 9h25 | Departure days Everyday | Cheapest price $39 |
The table below shows live departures for Frankfurt am Main Airport to Prague buses for today, Friday, July 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 10:40 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h30 | 7:10 PM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus · FlixBus | 10:40 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 9h10 | 7:50 PM Praha, Zličín | 1 transfer | |
FlixBus | 10:40 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h55 | 7:35 PM Praha, ÚAN Florenc | 0 transfersDirect | |
(Amsterdam -> Prague) | 10:00 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 6h48 | 4:48 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 11:30 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 7h25 | 6:55 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 11:30 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 9h25 | 8:55 AM Praha, Na Knížecí | 1 transfer | |
| Saturday, July 18 | |||||
FlixBus · FlixBus | 1:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h05 | 9:20 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 1:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h50 | 10:05 AM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 1:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 10h15 | 11:30 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 1:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 10h05 | 11:20 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 4:20 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h45 | 1:05 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 4:20 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 8h25 | 12:45 PM Praha, Na Knížecí | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Frankfurt am Main Airport to Prague run on average 10 times per day, taking around 8h 33m. Cheap bus tickets for this journey start at $15 (€12) if you book in advance.
There are 4 buses per day. The earliest bus runs at 08:40, the last at 23:15. The fastest bus covers the 259 miles (417 km) distance in 6h 45m.
Distance 259 miles (417 km) |
Average bus duration 8h 33m |
Cheapest ticket price $15 (€12) |
Buses per day 10 |
Direct buses 4 |
Fastest bus 6h 45m |
First bus 8:40 AM |
Last bus 11:15 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Sun |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Find answers to the most common questions about traveling from Frankfurt am Main Airport to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Frankfurt am Main Airport to Prague buses use the Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Na Knížecí. Use this guide to compare Frankfurt am Main Airport and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Here are some other resources that might have the information you need