- Must visit
Musée des Confluences
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
Cheapest price
$0.00
Average price
$-0.01
Fastest journey
7 h 38 m
Average duration
7 h 38 m
Trains per day
1
Distance
553 km
The best way to find a cheap train ticket from Frankfurt am Main Airport to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
It's difficult to get from Frankfurt am Main Airport to Lyon without transferring at least 2 times.
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Omio recommends booking the bus as it is the most popular option from Frankfurt am Main Airport to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $34. For those with little time consider booking a flight which can get you there in 2h 12m. The ticket price range depends on the travel mode: a bus costs an average of $34, and a flight costs an average of $168.
Distance: 343 miles (553 km)
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$158 Average price | $58 Average price Cheapest | $300 Average price | $180 Average price (fuel + tolls) |
6h 24m Average total duration 5h 54m Onboard + 30m Additional time* | 10h 27m Average total duration 9h 57m Onboard + 30m Additional time* | 5h 12m Average total duration Fastest 2h 12m Onboard + 3h 0m Additional time* | 6h 30m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Frankfurt am Main Airport to Lyon:
A bus is $101 (€81) less than a train for this route with tickets for a train from Frankfurt am Main Airport to Lyon costing on average $158 (€128).
A bus is $242 (€195) less than a flight for this route with tickets for a flight from Frankfurt am Main Airport to Lyon costing on average $300 (€242).
Other travel options to Lyon take longer:
Train takes on average 5h 54m.
Bus takes on average 9h 57m.
The journey is about 36m faster (5h 54m by train vs 6h 30m by car) and roughly $22 (€18) cheaper once you factor in fuel and tolls ($158 (€128) vs $180 (€145)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Direct services run with SNCF | TGV INOUI.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
The table below shows live departures for Frankfurt am Main Airport to Lyon trains for today, Thursday, May 28. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
9556+ 6617 | 8:53 AM Frankfurt (Main) Hbf | 7h03 | 3:56 PM Lyon Part Dieu | 1 transfer | |
5537+ 9590 | 11:01 AM Frankfurt (Main) Hbf | 6h58 | 5:59 PM Lyon Part Dieu | 1 transfer | |
9552 · 6627 | 12:53 PM Frankfurt (Main) Hbf | 7h01 | 7:54 PM Lyon Part Dieu | 1 transfer | |
9580 | 2:02 PM Frankfurt (Main) Hbf | 5h56 | 7:58 PM Lyon Part Dieu | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Frankfurt am Main Airport to Lyon run on average 3 times per day, taking around 5h 54m. Cheap train tickets for this journey start at $66 (€53) but you can travel from only $34 (€28) by bus.
There are 1 trains per day. The earliest train runs at 10:53, the last at 13:02. The fastest train covers the 343 miles (553 km) distance in 5h 56m.
Distance 343 miles (553 km) |
Average train duration 5h 54m |
Cheapest ticket price $66 (€53) |
Trains per day 3 |
Direct trains 1 |
Fastest train 5h 56m |
First train 10:53 AM |
Last train 1:02 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Mon |
Least Busy Day Tue |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
Lyon’s premier fine arts museum, housed in a former abbey near Place des Terreaux. Known for strong collections of painting, sculpture, antiquities, and decorative arts.
Museum of Roman Lyon paired with the city’s ancient theaters on Fourvière hill. A key stop for understanding Lugdunum, the Roman origins of Lyon.
Lyon’s atmospheric old quarter with Renaissance lanes, traboules, and riverfront views. It is the city’s classic strolling area and a top priority for first-time visitors.
One of Europe’s largest open squares and a central meeting point in Lyon. It is a practical orientation stop and a key place for city views toward Fourvière.
Lyon’s flagship urban park with broad walking paths, lake, botanical areas, and a zoo. It is one of the best places in the city for relaxation and scenic walks.
Light dumplings made with pike and panade, usually baked in a rich Nantua crayfish sauce. A classic Lyonnais bouchon specialty.
A traditional salad of frisée lettuce with lardons, croutons, and a poached egg. It is one of the city’s most iconic starter dishes.
Lyon’s famous sausage baked inside a soft brioche dough. It is a beloved charcuterie-based specialty found in many bouchons.
A landmark fine dining institution in Lyon, famed for historic prestige and elegant cuisine rooted in the city’s gastronomic heritage.
The city’s celebrated covered food market, ideal for sampling oysters, charcuterie, cheese, pastries, and many iconic Lyonnais products.
A respected traditional restaurant associated with chef Joseph Viola, celebrated for refined Lyonnais classics in a polished but welcoming setting.
Moderate for France: bakeries and bouchons are fair value, while central hotels and fine dining cost more.
Service is included by law. Leaving small change or 5-10% for great service is appreciated, not required. Round up for taxis.
Official public transport app
Lyon Part-Dieu -> Bellecour, Lyon
Find answers to the most common questions about traveling from Frankfurt am Main Airport to Lyon by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

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