- Must visit
Städel Museum
Major fine art museum on the Museumsufer, known for its outstanding European collection from the Middle Ages to contemporary art.
We are not able to find a bus between these two places.
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Omio recommends booking the bus as it is the most popular option from Lyon to Frankfurt am Main Airport among Omio's users. If you are prioritising price take the bus with prices starting from $37. For those with little time consider booking a flight which can get you there in 1h 27m. The ticket price range depends on the travel mode: a bus costs an average of $37, and a flight costs an average of $113.
Distance: 343 miles (553 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$51 Average price Cheapest | $133 Average price | $239 Average price | $177 Average price (fuel + tolls) |
11h 17m Average total duration 10h 47m Onboard + 30m Additional time* | 6h 24m Average total duration 5h 54m Onboard + 30m Additional time* | 4h 27m Average total duration Fastest 1h 27m Onboard + 3h 0m Additional time* | 6h 55m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Lyon to Frankfurt am Main Airport:
A bus is $82 (€68) less than a train for this route with tickets for a train from Lyon to Frankfurt am Main Airport costing on average $133 (€109).
A bus is $189 (€155) less than a flight for this route with tickets for a flight from Lyon to Frankfurt am Main Airport costing on average $239 (€197).
Other travel options to Frankfurt am Main Airport take longer:
Train takes on average 5h 54m.
Bus takes on average 10h 47m.
Tickets start at around $51 (€42) compared to roughly $177 (€146) in fuel and tolls — a saving of about $126 (€104). The journey takes 10h 47m versus 6h 55m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar Bus, Sindbad.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar Bus | Departure Time 01:05AM | Arrival Time 11:55AM | Duration 10h50 | Departure days Mon, Thu | Cheapest price $38 |
Operator BlaBlaCar Bus | Departure Time 01:10AM | Arrival Time 11:55AM | Duration 10h45 | Departure days Thu | Cheapest price $40 |
Operator FlixBus | Departure Time 01:20AM | Arrival Time 11:25AM | Duration 10h05 | Departure days Tue | Cheapest price $39 |
Operator BlaBlaCar Bus | Departure Time 01:20AM | Arrival Time 11:45AM | Duration 10h25 | Departure days Mon, Wed, Sat, Sun | Cheapest price $40 |
Operator BlaBlaCar Bus | Departure Time 02:20AM | Arrival Time 12:45PM | Duration 10h25 | Departure days Mon, Tue, Sat, Sun | Cheapest price $39 |
Operator FlixBus | Departure Time 02:20AM | Arrival Time 12:25PM | Duration 10h05 | Departure days Fri | Cheapest price $57 |
Operator BlaBlaCar Bus | Departure Time 03:20AM | Arrival Time 01:45PM | Duration 10h25 | Departure days Fri | Cheapest price $73 |
Operator FlixBus | Departure Time 06:35AM | Arrival Time 11:05PM | Duration 16h30 | Departure days Wed, Thu | Cheapest price $49 |
Operator FlixBus | Departure Time 07:35AM | Arrival Time 12:05AM | Duration 16h30 | Departure days Wed | Cheapest price $40 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 07:45AM | Duration 15h30 | Departure days Mon | Cheapest price $54 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 05:30AM | Duration 12h25 | Departure days Fri | Cheapest price $78 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 08:45AM | Duration 15h30 | Departure days Mon, Sat | Cheapest price $57 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 12:50PM | Duration 15h50 | Departure days Thu | Cheapest price $67 |
Operator FlixBus | Departure Time 11:00PM | Arrival Time 10:20AM | Duration 11h20 | Departure days Fri | Cheapest price $90 |
The table below shows live departures for Lyon to Frankfurt am Main Airport buses for today, Thursday, July 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:35 AM Lyon | 16h30 | 11:05 PM Frankfurt am Main Airport | 0 transfersDirect | |
![]() | 9:00 PM Lyon | 15h50 | 12:50 PM Frankfurt am Main Airport | 0 transfersDirect | |
| Friday, July 10 | |||||
FlixBus | 2:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 10h05 | 12:25 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
51511 | 3:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 10h25 | 1:45 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Lyon to Frankfurt am Main Airport run on average 7 times per day, taking around 10h 47m. Cheap bus tickets for this journey start at $37 (€30) if you book in advance.
There are 2 buses per day. The earliest bus runs at 00:05, the last at 22:00. The fastest bus covers the 343 miles (553 km) distance in 10h 5m.
Distance 343 miles (553 km) |
Average bus duration 10h 47m |
Cheapest ticket price $37 (€30) |
Buses per day 7 |
Direct buses 2 |
Fastest bus 10h 5m |
First bus 12:05 AM |
Last bus 10:00 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Fri |
Discover the best of Frankfurt am Main Airport — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Frankfurt am Main Airport trip today.
Major fine art museum on the Museumsufer, known for its outstanding European collection from the Middle Ages to contemporary art.
One of Germany's best natural history museums, especially popular for dinosaur skeletons and biodiversity displays.
Sculpture museum in a historic villa with an excellent collection spanning ancient Egypt to Neoclassicism.
Frankfurt's historic square with reconstructed timber-framed houses, civic buildings, and a classic old-town atmosphere.
Popular skyline viewpoint offering one of the best panoramic views over Frankfurt and the Main river.
Rebuilt old town quarter between Römer and cathedral, popular for its lanes, facades, and photogenic urban design.
Thin smoked pork sausages traditionally served with mustard and bread; a classic specialty from Frankfurt and one of the city’s best-known foods.
A cold herb sauce made with seven fresh herbs, usually served with boiled eggs and potatoes; a signature Frankfurt dish especially popular in spring.
A pungent sour-milk cheese marinated with onions and vinegar; a rustic Hessian tavern favorite closely associated with Frankfurt.
Recognized German dining brand at the airport, known for polished service, quality ingredients, and a more upscale atmosphere than typical terminal dining.
Well-known airport restaurant by chef Tim Mälzer, offering solid German and international comfort food in a polished casual setting at Frankfurt Airport.
Established casual airport spot for sandwiches, salads, coffee, and quick meals; convenient for travelers wanting a lighter option in a modern setting.
Airport prices are higher than in central Frankfurt. Coffee, snacks, and sit-down meals usually cost more than city averages.
Service is usually included. Round up small bills, or tip about 5-10% for good table service. Tipping is not expected for quick takeaway, but appreciated.
Official public transport app
Frankfurt Airport Regionalbahnhof -> Frankfurt am Main Hauptwache
Find answers to the most common questions about traveling from Lyon to Frankfurt am Main Airport by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Frankfurt am Main Airport, this guide helps you travel smarter and with confidence.

Most Lyon to Frankfurt am Main Airport buses use the Lyon, Gare Routière de Perrache to Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) station pair. Use this guide to compare Lyon and Frankfurt am Main Airport bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, Gare Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Bistro Lyonnais (0.2 km), Fast Food Express (0.3 km).
Free Wi-Fi. ATMs are located near the main entrance and in the shopping area.
Ticket office support is available at Lyon, Gare Perrache.
Available at Lyon, Gare Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Perrache: Elevators, ramps.
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