The cheapest and fastest buses from Lyon to Frankfurt am Main Airport
Cheapest price
$41
Average price
$50
Fastest journey
10 h 25 m
Average duration
12 h 32 m
Buses per day
5
Distance
553 km
The best way to find a cheap bus ticket from Lyon to Frankfurt am Main Airport is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Frankfurt am Main Airport will cost around $50 if you buy it on the day, but the cheapest tickets can be found for only $41.
Of the 5 buses that leave Lyon for Frankfurt am Main Airport on Mon, May 25, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, May 25 the direct buses cover the 553 km distance in an average of 12 h 32 m but if you time it right, some buses will get you there in just 10 h 25 m .
On Mon, May 25 the slowest buses will take 15 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1:20 AM10h25Lyon11:45 AMFrankfurt am Main Airport$411One-way0 transfers
2:20 AM10h25Lyon12:45 PMFrankfurt am Main Airport$421One-way0 transfers
1:05 AM10h50Lyon11:55 AMFrankfurt am Main Airport$481One-way0 transfers
4:15 PM15h30Lyon7:45 AMFrankfurt am Main Airport$551One-way0 transfers
5:15 PM15h30Lyon8:45 AMFrankfurt am Main Airport$621One-way0 transfers
2:20 AM10h25Lyon12:45 PMFrankfurt am Main Airport$421One-way0 transfers
1:20 AM10h25Lyon11:45 AMFrankfurt am Main Airport$411One-way0 transfers
1:05 AM10h50Lyon11:55 AMFrankfurt am Main Airport$481One-way0 transfers
5:15 PM15h30Lyon8:45 AMFrankfurt am Main Airport$621One-way0 transfers
4:15 PM15h30Lyon7:45 AMFrankfurt am Main Airport$551One-way0 transfers
Travel Information
Compare train, bus, and flight for Lyon to Frankfurt am Main Airport
Omio recommends booking the bus as it is the most popular option from Lyon to Frankfurt am Main Airport among Omio's users. If you are prioritising price take the bus with prices starting from $38. For those with little time consider booking a flight which can get you there in 1h 27m. The ticket price range depends on the travel mode: a bus costs an average of $38, and a flight costs an average of $115.
Distance: 343 miles (553 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$51 Average price Cheapest | $135 Average price | $243 Average price | $180 Average price (fuel + tolls) |
11h 17m Average total duration 10h 47m Onboard + 30m Additional time* | 6h 24m Average total duration 5h 54m Onboard + 30m Additional time* | 4h 27m Average total duration Fastest 1h 27m Onboard + 3h 0m Additional time* | 6h 55m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Lyon to Frankfurt am Main Airport:
A bus is $84 (€68) less than a train for this route with tickets for a train from Lyon to Frankfurt am Main Airport costing on average $135 (€109).
A bus is $192 (€155) less than a flight for this route with tickets for a flight from Lyon to Frankfurt am Main Airport costing on average $243 (€197).
Other travel options to Frankfurt am Main Airport take longer:
Train takes on average 5h 54m.
Bus takes on average 10h 47m.
Tickets start at around $51 (€42) compared to roughly $180 (€146) in fuel and tolls — a saving of about $128 (€104). The journey takes 10h 47m versus 6h 55m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar Bus, Sindbad.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Lyon to Frankfurt am Main Airport Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar Bus | Departure Time 01:05AM | Arrival Time 11:55AM | Duration 10h50 | Departure days Mon, Thu | Cheapest price $38 |
Operator BlaBlaCar Bus | Departure Time 01:10AM | Arrival Time 11:55AM | Duration 10h45 | Departure days Thu | Cheapest price $41 |
Operator BlaBlaCar Bus | Departure Time 01:20AM | Arrival Time 11:45AM | Duration 10h25 | Departure days Mon, Wed, Sat, Sun | Cheapest price $41 |
Operator BlaBlaCar Bus | Departure Time 02:20AM | Arrival Time 12:45PM | Duration 10h25 | Departure days Mon, Sat, Sun | Cheapest price $42 |
Operator BlaBlaCar Bus | Departure Time 03:20AM | Arrival Time 01:45PM | Duration 10h25 | Departure days Tue | Cheapest price $40 |
Operator FlixBus | Departure Time 05:20AM | Arrival Time 05:35PM | Duration 12h15 | Departure days Tue | Cheapest price $59 |
Operator FlixBus | Departure Time 06:35AM | Arrival Time 11:05PM | Duration 16h30 | Departure days Wed, Thu | Cheapest price $50 |
Operator FlixBus | Departure Time 07:35AM | Arrival Time 12:05AM | Duration 16h30 | Departure days Wed | Cheapest price $41 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 05:30AM | Duration 16h25 | Departure days Tue | Cheapest price $67 |
Operator FlixBus | Departure Time 04:05PM | Arrival Time 04:30AM | Duration 12h25 | Departure days Fri | Cheapest price $55 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 07:45AM | Duration 15h30 | Departure days Mon | Cheapest price $55 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 08:45AM | Duration 15h30 | Departure days Mon, Fri, Sat | Cheapest price $58 |
Operator FlixBus | Departure Time 06:05PM | Arrival Time 09:45AM | Duration 15h40 | Departure days Tue | Cheapest price $61 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 12:50PM | Duration 15h50 | Departure days Thu | Cheapest price $69 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 09:20AM | Duration 11h20 | Departure days Fri | Cheapest price $70 |
Operator FlixBus | Departure Time 11:00PM | Arrival Time 10:20AM | Duration 11h20 | Departure days Tue | Cheapest price $64 |
Live departures
Lyon to Frankfurt am Main Airport bus times
The table below shows live departures for Lyon to Frankfurt am Main Airport buses for tomorrow, Monday, May 25. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:05 AM Lyon | 10h50 | 11:55 AM Frankfurt am Main Airport | 0 transfersDirect | |
![]() | 1:20 AM Lyon | 10h25 | 11:45 AM Frankfurt am Main Airport | 0 transfersDirect | |
![]() | 2:20 AM Lyon | 10h25 | 12:45 PM Frankfurt am Main Airport | 0 transfersDirect | |
![]() | 4:15 PM Lyon | 15h30 | 7:45 AM Frankfurt am Main Airport | 0 transfersDirect | |
![]() | 5:15 PM Lyon | 15h30 | 8:45 AM Frankfurt am Main Airport | 0 transfersDirect |
Find all the dates and times for this journey
Compare prices and tickets Lyon to Frankfurt am Main Airport by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 25
May 26
May 27
May 28
May 29
May 30
May 31
Why should you book Lyon to Frankfurt am Main Airport buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus or Sindbad to find the best option for your trip from Lyon to Frankfurt am Main Airport.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Lyon to Frankfurt am Main Airport.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus or Sindbad to find the best option for your trip from Lyon to Frankfurt am Main Airport.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Lyon to Frankfurt am Main Airport.
Journey information
Overview: Bus from Lyon to Frankfurt am Main Airport
Buses from Lyon to Frankfurt am Main Airport run on average 7 times per day, taking around 10h 47m. Cheap bus tickets for this journey start at $38 (€30) if you book in advance.
There are 2 buses per day. The earliest bus runs at 00:05, the last at 22:00. The fastest bus covers the 343 miles (553 km) distance in 10h 5m.
Distance 343 miles (553 km) |
Average bus duration 10h 47m |
Cheapest ticket price $38 (€30) |
Buses per day 7 |
Direct buses 2 |
Fastest bus 10h 5m |
First bus 12:05 AM |
Last bus 10:00 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Fri |
Bus providers: FlixBus, BlaBlaCar Bus, Sindbad from Lyon to Frankfurt am Main AirportYou can travel by bus between Lyon to Frankfurt am Main Airport with FlixBus, BlaBlaCar Bus, Sindbad for as low as $38 (€30). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Sindbad
BlaBlaCar Bus
FAQs: Bus from Lyon to Frankfurt am Main Airport
Find answers to the most common questions about traveling from Lyon to Frankfurt am Main Airport by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Frankfurt am Main Airport, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Sindbad
- Assistance
- Priority boarding
- Accessible restrooms.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Sindbad
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Sindbad
- One carry-on bag up to 5kg and one checked bag up to 25kg.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Sindbad
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Sindbad
- Small pets allowed in carriers
- larger pets may require prior arrangement.
popular bus stations
Popular bus stations from Lyon to Frankfurt am Main Airport
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Bistro Lyonnais (0.2 km)
- Fast Food Express (0.3 km).
- Available outside the main entrance.
- Elevators, ramps
- Available on the concourse.
- Bus: C21, C22, S1 Metro: A Train: TER
Most popular bus connections from Lyon
More options for your journey from Lyon to Frankfurt am Main Airport
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