- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price on Sep 19
$43
Average ticket price on Sep 19
$58
Fastest journey on Sep 19
6 h 18 m
Average journey duration on Sep 19
8 h
Buses on Sep 19
16
Distance
413 km
The best way to find a cheap bus ticket from Darmstadt to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Darmstadt to Prague will cost around $58 if you buy it on the day, but the cheapest tickets can be found for only $43.
On Sat, Sep 19, we found 16 buses from Darmstadt to Prague, including 2 direct services.
On Sat, Sep 19 the direct buses cover the 413 km distance in an average of 8 h but if you time it right, some buses will get you there in just 6 h 18 m .
On Sat, Sep 19 the slowest buses will take 9 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
(Amsterdam -> Prague)
(Amsterdam -> Prague)
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FlixBus
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FlixBus
(Amsterdam -> Prague)
(Amsterdam -> Prague)
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FlixBusOmio recommends booking the flight as it is the most popular option from Darmstadt to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $68 For those with little time, consider booking a flight, which has an average total journey time of 4h 43m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of $68, while a flight costs an average of $458.
Distance: 256 miles (413 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$68 Average price Cheapest | $458 Average price | $130 Average price | $113 Average price (fuel + tolls) |
11h 5m Average total duration 10h 35m Onboard + 30m Additional time* | 4h 43m Average total duration Fastest 2h 43m Onboard + 2h 0m Additional time* | 7h 45m Average total duration 7h 15m Onboard + 30m Additional time* | 5h 44m Average total duration (door-to-door) |
0.4 - 1.0kg CO2 emissions | 1.2 - 2.5kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Darmstadt to Prague:
A bus is $62 less than a train for this route with tickets for a train from Darmstadt to Prague costing on average $130.
A bus is $390 less than a flight for this route with tickets for a flight from Darmstadt to Prague costing on average $458.
Other travel options to Prague take longer:
Train takes on average 7h 15m.
Bus takes on average 10h 35m.
Tickets start at around $68 compared to roughly $113 in fuel and tolls — a saving of about $45. The journey takes 10h 35m versus 5h 44m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by KLR.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:15AM | Arrival Time 01:20PM | Duration 12h05 | Departure days Sat, Sun | Cheapest price $60 |
Operator FlixBus | Departure Time 05:20AM | Arrival Time 05:45PM | Duration 12h25 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $42 |
Operator BlaBlaCar | Departure Time 05:30AM | Arrival Time 11:00AM | Duration 5h30 | Departure days Fri | Cheapest price $65 |
Operator FlixBus | Departure Time 07:40AM | Arrival Time 05:40PM | Duration 10h00 | Departure days Mon, Sat | Cheapest price $56 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 12:20PM | Duration 4h20 | Departure days Sun | Cheapest price $55 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 08:00PM | Duration 10h20 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $37 |
Operator FlixBus | Departure Time 09:50AM | Arrival Time 09:50PM | Duration 12h00 | Departure days Mon, Fri, Sat, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 11:40AM | Arrival Time 09:40PM | Duration 10h00 | Departure days Mon, Fri, Sat | Cheapest price $50 |
Operator FlixBus | Departure Time 12:21PM | Arrival Time 10:55PM | Duration 10h34 | Departure days Sun | Cheapest price $88 |
Operator FlixTrain | Departure Time 01:40PM | Arrival Time 11:35PM | Duration 9h55 | Departure days Fri | Cheapest price $100 |
Operator FlixBus | Departure Time 01:40PM | Arrival Time 11:55PM | Duration 10h15 | Departure days Mon, Thu, Fri, Sat | Cheapest price $51 |
Operator FlixBus | Departure Time 02:21PM | Arrival Time 11:10PM | Duration 8h49 | Departure days Mon, Tue, Wed, Thu, Sat | Cheapest price $37 |
Operator FlixBus | Departure Time 03:40PM | Arrival Time 01:40AM | Duration 10h00 | Departure days Tue, Wed, Thu, Sun | Cheapest price $37 |
Operator FlixBus | Departure Time 05:40PM | Arrival Time 02:50AM | Duration 9h10 | Departure days Thu, Fri, Sun | Cheapest price $55 |
Operator FlixTrain | Departure Time 05:40PM | Arrival Time 03:30AM | Duration 9h50 | Departure days Thu, Fri, Sun | Cheapest price $55 |
Operator BlaBlaCar | Departure Time 06:20PM | Arrival Time 11:30PM | Duration 5h10 | Departure days Fri | Cheapest price $52 |
Operator FlixBus | Departure Time 06:21PM | Arrival Time 07:30AM | Duration 13h09 | Departure days Fri, Sun | Cheapest price $66 |
Operator KLR | Departure Time 07:10PM | Arrival Time 07:50AM | Duration 12h40 | Departure days Mon, Tue, Wed, Sun | Cheapest price $25 |
Operator RegioJet a.s. | Departure Time 10:00PM | Arrival Time 04:48AM | Duration 6h48 | Departure days Everyday | Cheapest price $32 |
Operator RegioJet a.s. | Departure Time 10:30PM | Arrival Time 04:48AM | Duration 6h18 | Departure days Everyday | Cheapest price $32 |
Operator FlixBus | Departure Time 11:55PM | Arrival Time 10:10AM | Duration 10h15 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $38 |
The table below shows live departures for Darmstadt to Prague buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
(Amsterdam -> Prague) | 10:00 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 6h48 | 4:48 AM Praha, ÚAN Florenc | 0 transfersDirect | |
(Amsterdam -> Prague) | 10:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 6h18 | 4:48 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 11:55 PM Darmstadt, Lise-Meitner-Str. / Europaplatz | 10h15 | 10:10 AM Praha, ÚAN Florenc | 1 transfer | |
| Saturday, September 19 | |||||
FlixBus · FlixBus | 1:15 AM Darmstadt, Lise-Meitner-Str. / Europaplatz | 12h05 | 1:20 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 1:15 AM Darmstadt, Lise-Meitner-Str. / Europaplatz | 12h15 | 1:30 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 5:20 AM Darmstadt, Lise-Meitner-Str. / Europaplatz | 12h25 | 5:45 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 5:20 AM Darmstadt, Lise-Meitner-Str. / Europaplatz | 12h10 | 5:30 PM Prague, Central Train Station | 1 transfer | |
FlixBus+ FlixTrain | 7:40 AM Darmstadt Hbf | 10h00 | 5:40 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus+ FlixTrain | 7:40 AM Darmstadt Hbf | 10h20 | 6:00 PM Prague, Central Train Station | 1 transfer | |
FlixBus+ FlixTrain | 9:40 AM Darmstadt Hbf | 10h20 | 8:00 PM Prague, Central Train Station | 1 transfer | |
FlixBus+ FlixTrain | 9:40 AM Darmstadt Hbf | 9h30 | 7:10 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 9:50 AM Darmstadt, Lise-Meitner-Str. / Europaplatz | 12h00 | 9:50 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus+ FlixTrain | 11:40 AM Darmstadt Hbf | 10h00 | 9:40 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus+ FlixTrain | 1:40 PM Darmstadt Hbf | 10h15 | 11:55 PM Prague, Central Train Station | 1 transfer | |
FlixBus+ FlixTrain | 2:21 PM Darmstadt Hbf | 8h34 | 10:55 PM Praha, Na Knížecí | 1 transfer | |
FlixBus+ FlixTrain | 2:21 PM Darmstadt Hbf | 8h49 | 11:10 PM Praha, ÚAN Florenc | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Darmstadt to Prague run on average 5 times per day, taking around 10h 35m. Cheap bus tickets for this journey start at $28 but you can travel from only $9 by train.
The earliest bus runs at 01:00, the last at 23:55. The fastest bus covers the 256 miles (413 km) distance in 7h 30m.
Distance 256 miles (413 km) |
Average bus duration 10h 35m |
Cheapest ticket price $28 |
Buses per day 5 |
Fastest bus 7h 30m |
First bus 1:00 AM |
Last bus 11:55 PM |
Cheapest Month Jun |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jul - Sep |
Busiest Day Sun |
Least Busy Day Wed |
Best time to book 14 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Find answers to the most common questions about traveling from Darmstadt to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Darmstadt to Prague buses use the Darmstadt, Lise-Meitner-Str. / Europaplatz to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Hlavní Nádraží. Use this guide to compare Darmstadt and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Darmstadt, Lise-Meitner-Str. / Europaplatz is 1 km from Darmstadt city centre. Public transport options include:
Darmstadt, Lise-Meitner-Str. / Europaplatz has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Darmstadt, Lise-Meitner-Str. / Europaplatz. ATMs are available at Darmstadt, Lise-Meitner-Str. / Europaplatz.
Ticket office support is available at Darmstadt, Lise-Meitner-Str. / Europaplatz.
Available at Darmstadt, Lise-Meitner-Str. / Europaplatz: Parking, Taxis, WC.
Accessibility facilities are available at Darmstadt, Lise-Meitner-Str. / Europaplatz: Basic accessibility features available.
Darmstadt, Busbahnhof Zweifalltorweg is 1 km from Darmstadt city centre. Public transport options include:
Darmstadt, Busbahnhof Zweifalltorweg has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Fast food and cafes available nearby.
Wi-Fi is available at Darmstadt, Busbahnhof Zweifalltorweg. ATMs are aTM available within a short walking distance.
Ticket office support is available at Darmstadt, Busbahnhof Zweifalltorweg.
Available at Darmstadt, Busbahnhof Zweifalltorweg: Parking, Taxis, WC.
Accessibility facilities are available at Darmstadt, Busbahnhof Zweifalltorweg: Ramps and assistance available for disabled access.
Darmstadt, Hauptbahnhof Fernbusse is 1 km from Darmstadt city centre. Public transport options include:
Darmstadt, Hauptbahnhof Fernbusse has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Small cafes and food stalls nearby.
Wi-Fi is available at Darmstadt, Hauptbahnhof Fernbusse. ATMs are available at Darmstadt, Hauptbahnhof Fernbusse.
Ticket office support is available at Darmstadt, Hauptbahnhof Fernbusse.
Available at Darmstadt, Hauptbahnhof Fernbusse: Parking, Taxis, WC.
Accessibility facilities are available at Darmstadt, Hauptbahnhof Fernbusse: Station is wheelchair accessible.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Here are some other resources that might have the information you need