- Must visit
Antonino Salinas Regional Archaeological Museum
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Cheapest price
$24
Average price
$24
Fastest journey
4 h 23 m
Average duration
4 h 38 m
Buses per day
4
Distance
170 km
The best way to find a cheap bus ticket from Comiso to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Comiso to Palermo will cost around $24 if you buy it on the day, but the cheapest tickets can be found for only $24.
It's difficult to get from Comiso to Palermo without transferring at least once.
Regionale 5470 · treno 5513 effettuato con bus PA331
Regionale 5466 · treno 5503 effettuato con bus PA325
2490 · 2487
2490 · 2487
Regionale 5470 · treno 5513 effettuato con bus PA331
Regionale 5466 · treno 5503 effettuato con bus PA325
2490 · 2487
2490 · 2487Omio recommends booking the train as it is the most popular option from Comiso to Palermo among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a bus which can get you there in 3h 53m. The ticket price range depends on the travel mode: a bus costs an average of $24, and a train costs an average of $23.
Distance: 105 miles (170 km)
| Bus | Most popular Train |
|---|---|
$24 Average price Cheapest | $31 Average price |
4h 23m Average total duration Fastest 3h 53m Onboard + 30m Additional time* | 6h 13m Average total duration 5h 43m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
This is compared to other travel options from Comiso to Palermo:
A bus is $7 less than a train for this route with tickets for a train from Comiso to Palermo costing on average $31.
Other travel options to Palermo take longer:
Train takes on average 5h 43m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Regionale | Departure Time 06:33AM | Arrival Time 10:58AM | Duration 4h25 | Departure days Mon, Wed, Thu, Sat | Cheapest price $24 |
Operator Sais Regional | Departure Time 06:40AM | Arrival Time 11:35AM | Duration 4h55 | Departure days Mon, Wed, Thu, Fri, Sat | Cheapest price $24 |
Operator Azienda Siciliana Trasporti | Departure Time 12:55PM | Arrival Time 04:30PM | Duration 3h35 | Departure days Sun | Cheapest price $0.00 |
Operator Regionale | Departure Time 02:35PM | Arrival Time 06:58PM | Duration 4h23 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $24 |
The table below shows live departures for Comiso to Palermo buses for today, Tuesday, August 25. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 5470 · treno 5513 effettuato con bus PA331 | 2:35 PM Comiso station | 4h23 | 6:58 PM Palermo Centrale | 1 transfer | |
| Wednesday, August 26 | |||||
Regionale 5466 · treno 5503 effettuato con bus PA325 | 6:33 AM Comiso station | 4h25 | 10:58 AM Palermo Centrale | 1 transfer | |
2490 · 2487 | 6:40 AM Comiso, Via Ghandi (Fermata Sais Comiso) | 4h50 | 11:30 AM Palermo, Oreto - Orsi | 1 transfer | |
2490 · 2487 | 6:40 AM Comiso, Via Ghandi (Fermata Sais Comiso) | 4h55 | 11:35 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Comiso to Palermo run on average 2 times per day, taking around 3h 53m. Cheap bus tickets for this journey start at $24 but you can travel from only $23 by train.
The earliest bus runs at 04:21, the last at 17:31. The fastest bus covers the 105 miles (170 km) distance in 3h 50m.
Distance 105 miles (170 km) |
Average bus duration 3h 53m |
Cheapest ticket price $24 |
Buses per day 2 |
Fastest bus 3h 50m |
First bus 4:21 AM |
Last bus 5:31 PM |
Cheapest Month Aug |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Wed |
Best time to book 3 days |
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Historic rooms and vivid majolica floors showcase aristocratic Palermo. Visit for decorative arts, period interiors and city history.
Housed in the grand Steri Palace, this museum presents the Sicilian Inquisition’s story through cells, graffiti and historical documents.
Palermo’s elegant main boulevard links major monuments, shops and theaters. Ideal for first walks and observing the city’s layered architecture.
This historic street cuts across the old center and hosts markets, churches and daily life. A lively route for exploring local Palermo.
A bustling old quarter famous for layered street life, churches and market culture. Best explored on foot for atmosphere and urban history.
Crisp fried rice ball stuffed with ragù, peas and caciocavallo. A Sicilian street food icon widely loved in Palermo.
Soft sesame-topped bun filled with spleen and lung, often with caciocavallo or ricotta. A classic Palermo street food with deep local roots.
Pasta with sardines, wild fennel, pine nuts and raisins. Its sweet-savory flavor reflects Palermo's Arab-Norman culinary heritage.
Refined Michelin-starred restaurant known for creative Sicilian tasting menus in an elegant, intimate setting.
Historic seafood restaurant near the port, praised for fresh catch, raw dishes and classic Palermo fish recipes.
Legendary no-frills street-food stop celebrated for pane con la milza and authentic local sandwiches loved by residents.
Moderate for Italy. Street food and local meals are affordable, while hotels in peak season cost more. Public transport is cheap, keeping overall tourist costs reasonable.
Service is often included or modest. Round up or leave 5-10% for great restaurant service. Taxis are usually rounded up. Small change is fine in cafes.
Find answers to the most common questions about traveling from Comiso to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

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