- Must visit
Galleria Regionale della Sicilia - Palazzo Abatellis
Major Sicilian art museum in a Gothic-Catalan palace, best known for Antonello da Messina and medieval to Renaissance works.
Cheapest price
$0.00
Average price
$-0.01
Fastest journey
3 h 35 m
Average duration
3 h 35 m
Buses per day
1
Distance
170 km
The best way to find a cheap bus ticket from Comiso to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
Of the 1 buses that leave Comiso for Palermo on Sun, Jul 12, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jul 12 the direct buses cover the 170 km distance in an average of 3 h 35 m but if you time it right, some buses will get you there in just 3 h 35 m .
On Sun, Jul 12 the slowest buses will take 3 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the train as it is the most popular option from Comiso to Palermo among Omio's users. If you are prioritising price take the train with prices starting from $22. For those with little time consider booking a bus which can get you there in 3h 48m. The ticket price range depends on the travel mode: a train costs an average of $22, and a bus costs an average of $23.
Distance: 105 miles (170 km)
| Bus | Most popular Train |
|---|---|
$24 Average price | $24 Average price Cheapest |
4h 18m Average total duration Fastest 3h 48m Onboard + 30m Additional time* | 4h 20m Average total duration 3h 50m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
This is compared to other travel options from Comiso to Palermo:
A train is $0.17 (€0.14) less than a bus for this route with tickets for a bus from Comiso to Palermo costing on average $24 (€20).
Other travel options to Palermo take longer:
Train takes on average 3h 50m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Sais Regional | Departure Time 04:40AM | Arrival Time 09:35AM | Duration 4h55 | Departure days Thu, Fri | Cheapest price $25 |
Operator Sais Regional | Departure Time 05:40AM | Arrival Time 10:35AM | Duration 4h55 | Departure days Fri | Cheapest price $23 |
Operator Regionale | Departure Time 06:33AM | Arrival Time 10:58AM | Duration 4h25 | Departure days Tue, Wed | Cheapest price $23 |
Operator Sais Regional | Departure Time 06:40AM | Arrival Time 11:30AM | Duration 4h50 | Departure days Mon, Tue, Wed | Cheapest price $23 |
Operator Azienda Siciliana Trasporti | Departure Time 12:55PM | Arrival Time 04:30PM | Duration 3h35 | Departure days Sun | Cheapest price $0.00 |
Operator BlaBlaCar | Departure Time 02:00PM | Arrival Time 06:00PM | Duration 4h00 | Departure days Sat | Cheapest price $20 |
Operator Regionale | Departure Time 02:35PM | Arrival Time 06:58PM | Duration 4h23 | Departure days Tue, Wed | Cheapest price $23 |
The table below shows live departures for Comiso to Palermo buses for today, Saturday, July 11. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:00 PM Comiso | 4h00 | 6:00 PM Palermo | 0 transfersDirect | |
![]() | 2:00 PM Comiso | 4h00 | 6:00 PM Palermo | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Comiso to Palermo run on average 4 times per day, taking around 3h 48m. Cheap bus tickets for this journey start at $23 (€19) but you can travel from only $22 (€18) by train.
The earliest bus runs at 04:21, the last at 17:31. The fastest bus covers the 105 miles (170 km) distance in 4h 55m.
Distance 105 miles (170 km) |
Average bus duration 3h 48m |
Cheapest ticket price $23 (€19) |
Buses per day 4 |
Fastest bus 4h 55m |
First bus 4:21 AM |
Last bus 5:31 PM |
Cheapest Month Jul |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 3 days |
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Major Sicilian art museum in a Gothic-Catalan palace, best known for Antonello da Messina and medieval to Renaissance works.
One of Italy's oldest archaeological museums, with important Punic, Greek and Roman collections from Sicily and the Mediterranean.
Well-preserved aristocratic residence showing historic interiors, furnishings and decorative arts from Palermo's noble past.
Historic street market area full of energy, local life and vivid scenes, popular with visitors and photographers.
Elegant square famed for its monumental fountain and surrounding historic buildings in the heart of the old city.
Major pedestrian-friendly street linking key historic sights, busy with architecture, shops and constant city life.
Fried rice balls stuffed with ragù, mozzarella, or butter and ham. A Palermo street food icon with a famous local feminine name form.
A traditional sandwich filled with veal spleen and lung, often topped with ricotta or caciocavallo. One of Palermo’s most distinctive historic street foods.
Pasta with sardines, wild fennel, raisins, pine nuts, and anchovies. It reflects the island’s Arab-Norman culinary heritage and sweet-savory style.
Well-regarded restaurant serving polished Sicilian cooking with local ingredients, including pasta, seafood, and traditional Palermo flavors in an elegant casual space.
Famous pastry shop and café celebrated for cannoli, cassata, and other Sicilian sweets. A strong choice for dessert and breakfast in Palermo.
Established restaurant near the historic center, appreciated for refined Sicilian dishes, seasonal produce, and a warm atmosphere blending tradition and creativity.
Generally cheaper than Rome or Milan. Street food and casual dining are affordable, while central hotels cost more in peak season.
Service is often included or minimal. Tipping is not required, but leaving EUR 1-2 at cafes or 5-10% in restaurants for good service is appreciated. Round up taxi fares.
Find answers to the most common questions about traveling from Comiso to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

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