Siena to Palermo bus with FlixBus

Wed, Feb 04
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The cheapest and fastest buses from Siena to Palermo

Showing times and prices for Feb 05

Cheapest price

$156

Average price

$159

Fastest journey

16 h 5 m

Average duration

17 h 50 m

Buses per day

2

Distance

603 km

Cheap tickets

The best way to find a cheap bus ticket from Siena to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Siena to Palermo will cost around $159 if you buy it on the day, but the cheapest tickets can be found for only $156.

Fast buses

Of the 2 buses that leave Siena for Palermo on Thu, Feb 05, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Thu, Feb 05 the direct buses cover the 603 km distance in an average of 17 h 50 m but if you time it right, some buses will get you there in just 16 h 5 m .

On Thu, Feb 05 the slowest buses will take 19 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
07:20PM19h35
Siena
02:55PMPalermo
$1561One-way
0 transfers
FlixBus
04:55PM16h05
Siena
09:00AMPalermo
$1611One-way
0 transfers

Travel Information

Compare train, bus, flight, and ferry for Siena to Palermo

Omio recommends booking the bus as it is the most popular option from Siena to Palermo among Omio's users. If you are prioritising price take the ferry with prices starting from €36. For those with little time consider booking a flight which can get you there in 1h 23m. The ticket price range depends on the travel mode: a ferry costs an average of €36, and a train costs an average of €82.

Distance: 374 miles (603 km)

Compare bus with

Most popular
Bus
Flight
Train
Ferry

€72

Average price

€109

Average price

€134

Average price

€51

Average price

Cheapest

16h 46m

Average total duration

16h 16m

Onboard

+

30m

Additional time*

4h 23m

Average total duration

Fastest

1h 23m

Onboard

+

3h 0m

Additional time*

16h 37m

Average total duration

16h 7m

Onboard

+

30m

Additional time*

20h 30m

Average total duration

19h 30m

Onboard

+

1h 0m

Additional time*

FlixBus

Most popular bus company

Ryanair

Most popular airline

Intercity Notte

Most popular train company

Grimaldi

Most popular ferry company

Direct Options

Direct Options

Direct Options

Direct Options

Siena to Palermo Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
07:00PM
Arrival Time
02:25PM
Duration
19h25
Departure days
Mon, Tue
Cheapest price
$32
Operator
FlixBus
Departure Time
09:00PM
Arrival Time
02:25PM
Duration
17h25
Departure days
Mon, Tue
Cheapest price
$32

Live departures

Siena to Palermo bus times

The table below shows live departures for Siena to Palermo buses for tomorrow, Thursday, February 5. You can also manually refresh the results below to see updated bus journeys.

Last updated at 5:41 PM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus4:55 PM Siena
16h05
9:00 AM Palermo0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Siena to Palermo by train, bus, flight, or ferry

Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
Feb 05
Fri
Feb 06
Sat
Feb 07
Sun
Feb 08
Mon
Feb 09
Tue
Feb 10
Wed
Feb 11

Why should you book Siena to Palermo buses with Omio?

FlixBus as well as Itabus offer buses services from Siena to Palermo.
Omio is an official ticket reseller for all your travel options from Siena to Palermo.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus to find the best option for your trip from Siena to Palermo.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Siena to Palermo.

Why book with Omio over Wanderu or Checkmybus?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus to find the best option for your trip from Siena to Palermo.
  • Multiple modes of transport: Omio allows you to compare travel options including train, bus, flight and ferry to find the ideal travel option from Siena to Palermo.

Journey information

Overview: Bus from Siena to Palermo

ItalyItaly
ItalyItaly
Icon of bus

Buses from Siena to Palermo run on average 6 times per day, taking around 16h 16m. Cheap bus tickets for this journey start at $43 (€34) but you can travel from only $31 (€25) by flight.

There are 1 buses per day. The earliest bus runs at 00:52, the last at 21:46. The fastest bus covers the 374 miles (603 km) distance in 16h 5m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $31 (€25)
Distance
374 miles (603 km)
Average bus duration
16h 16m
Cheapest ticket price
$43 (€34)
Buses per day
6
Direct buses
1
Fastest bus
16h 5m
First bus
00:52
Last bus
21:46
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $31 (€25)

Bus providers: FlixBus, Itabus from Siena to PalermoYou can travel by bus between Siena to Palermo with FlixBus, Itabus for as low as $31 (€25). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
16h 5m
Cheapest Price
$45 (€36)
FlixBus frequency
6 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Itabus

About
Itabus is a leading bus company in Italy, providing reliable and comfortable transportation services to its customers. Itabus operates a fleet of modern buses, ranging from luxury coaches to standard buses, all equipped with air conditioning, comfortable seating, and onboard entertainment.
Luggage & cancellation policy
Average Duration
20h 35m
Cheapest Price
$138 (€110)
Itabus frequency
1 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 20kg.
Additional luggage
5€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Dedicated seating areas; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.

FAQs: Bus from Siena to Palermo

Find answers to the most common questions about traveling from Siena to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Siena to Palermo can start from as little as $43 (€34) when you book in advance. The average bus ticket price for Siena to Palermo is $90 (€72) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Siena to Palermo is 16h 5m to travel the 374 miles (603 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Siena to Palermo leaves at 12:52 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Siena to Palermo leaves at 9:46 PM.
Yes, there are 1 direct buses a day from Siena to Palermo with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Siena to Palermo, you can count on FlixBus, Itabus for the best way to get you to Palermo. You can also check all possible bus companies who offer a service between Siena and Palermo and compare the amenities they offer before buying a bus ticket.
A trip to Palermo from Siena is worth doing but not as a day trip with a journey time of 16h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Siena to Palermo is May.
It's helpful to compare your options as there are 4 ways to travel between Siena and Palermo including taking a train, bus, flight, and ferry.
Yes, the following accessibility options are available when taking the bus from Siena to Palermo:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
  • Itabus
    • Assistance
    • Dedicated seating areas
    • Accessible restrooms.
Yes, there are bathrooms on board the bus from Siena to Palermo for bus company FlixBus, Itabus.
Some of the most interesting sights to explore in Palermo are:
  • Palermo Cathedral, a stunning architectural blend of Norman, Moorish, and Baroque styles
  • Teatro Massimo, Italy's largest opera house known for its grand performances and impressive acoustics
  • Palazzo dei Normanni, a historic palace featuring the exquisite Palatine Chapel with its Byzantine mosaics
  • Quattro Canti, a Baroque square at the intersection of Palermo's two main streets, known for its symmetrical fountains and statues
  • Orto Botanico di Palermo, a lush botanical garden showcasing diverse plant species.
The best things to do in Palermo include:
  • Capuchin Catacombs, an eerie yet fascinating underground cemetery with mummified remains
  • Ballarò Market, a bustling street market offering a taste of local Sicilian produce and culture
  • Explore the vibrant street art in the Vucciria district
  • Take a cooking class to learn how to make traditional Sicilian dishes
  • Enjoy a leisurely stroll along the picturesque Foro Italico promenade.
Whether you can cancel your bus ticket from Siena to Palermo depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
  • Itabus
    • You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Yes, bikes are allowed on board the bus with bus company FlixBus, Itabus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Siena to Palermo.
Yes, the following luggage options are included when booking a bus ticket from Siena to Palermo:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
  • Itabus
    • One carry-on bag up to 10kg and one checked bag up to 20kg.
Yes, the following additional luggage options are available when booking a bus ticket from Siena to Palermo:
  • FlixBus
    • Additional luggage can be purchased for a fee.
  • Itabus
    • 5€ per additional bag.
Yes, you can bring your pet on the bus from Siena to Palermo. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
  • Itabus
    • Small pets allowed in carriers
    • larger pets must be leashed and muzzled.
You can reserve your seat on the bus from Siena to Palermo with the following bus company: FlixBus, Itabus
Yes, there are USB plugs on board the bus from Siena to Palermo with the following bus company: FlixBus, Itabus.
Yes, there is Wifi on board the bus from Siena to Palermo with the following bus company: FlixBus, Itabus.

popular bus stations

Popular bus stations from Siena to Palermo

Siena
Palermo
Siena, Stazione FS (Piazzale Carlo Rosselli)
information
Siena, Siena/Viale Pietro Toselli
information
Siena, P.za Gramsc
information

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