Siena to Palermo bus with FlixBus

Thu, Nov 06
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FlixBus
Itabus
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Rede Expressos
1,000+ travel companies
FlixBus
Itabus
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
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The cheapest and fastest buses from Siena to Palermo

Showing times and prices for Nov 07

Cheapest price

$50

Average price

$78

Fastest journey

17 h 25 m

Average duration

18 h 28 m

Buses per day

2

Distance

603 km

Cheap tickets

The best way to find a cheap bus ticket from Siena to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Siena to Palermo will cost around $78 if you buy it on the day, but the cheapest tickets can be found for only $50.

Fast buses

Of the 2 buses that leave Siena for Palermo on Fri, Nov 07, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Fri, Nov 07 the direct buses cover the 603 km distance in an average of 18 h 28 m but if you time it right, some buses will get you there in just 17 h 25 m .

On Fri, Nov 07 the slowest buses will take 19 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
04:55PM19h30
Siena
12:25PMPalermo
$501One-way
0 transfers
FlixBus
07:00PM17h25
Siena
12:25PMPalermo
$1051One-way
0 transfers

Travel Information

Compare train, bus, flight, and ferry for Siena to Palermo

Omio recommends booking the bus as it is the most popular option from Siena to Palermo among Omio's users. If you are prioritising price take the ferry with prices starting from €36. For those with little time consider booking a flight which can get you there in 1h 23m. The ticket price range depends on the travel mode: a ferry costs an average of €36, and a train costs an average of €82.

Distance: 374 miles (603 km)

Compare bus with

Most popular
Bus
Flight
Train
Ferry

€72

Average price

€109

Average price

€134

Average price

€51

Average price

Cheapest

16h 46m

Average total duration

16h 16m

Onboard

+

30m

Additional time*

4h 23m

Average total duration

Fastest

1h 23m

Onboard

+

3h 0m

Additional time*

16h 37m

Average total duration

16h 7m

Onboard

+

30m

Additional time*

20h 30m

Average total duration

19h 30m

Onboard

+

1h 0m

Additional time*

FlixBus

Most popular bus company

Ryanair

Most popular airline

Intercity Notte

Most popular train company

Grimaldi

Most popular ferry company

Direct Options

Direct Options

Direct Options

Direct Options

Siena to Palermo Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
11:55AM
Arrival Time
11:00AM
Duration
23h05
Departure days
Mon
Cheapest price
$104
Operator
FlixBus
Departure Time
06:55PM
Arrival Time
11:00AM
Duration
16h05
Departure days
Mon, Wed
Cheapest price
$65
Operator
FlixBus
Departure Time
09:00PM
Arrival Time
02:25PM
Duration
17h25
Departure days
Mon
Cheapest price
$78

Live departures

Siena to Palermo bus times

The table below shows live departures for Siena to Palermo buses for today, Thursday, November 6. You can also manually refresh the results below to see updated bus journeys.

Last updated at 1:50 AM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus4:55 PM Siena
16h05
9:00 AM Palermo0 transfersDirect
meinfernbus_flixbus7:20 PM Siena
19h35
2:55 PM Palermo0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Siena to Palermo by train, bus, flight, or ferry

Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Nov 07
Sat
Nov 08
Sun
Nov 09
Mon
Nov 10
Tue
Nov 11
Wed
Nov 12
Thu
Nov 13

Journey information

Overview: Bus from Siena to Palermo

ItalyItaly
ItalyItaly
Icon of bus
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $31 (€25)
Distance
374 miles (603 km)
Average bus duration
16h 16m
Cheapest ticket price
$42 (€34)
Buses per day
6
Direct buses
1
Fastest bus
16h 5m
First bus
00:52
Last bus
21:46

Key Takeaways

Train Ticket Prices
  • Budget Options: Train tickets from Siena to Palermo start from as low as $42 (€34) if booked well in advance.
  • Standard Fares: Typically, trains cost $88 (€72) depending on the train type and class.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $31 (€25)

Bus providers: FlixBus, Itabus from Siena to PalermoYou can travel by bus between Siena to Palermo with FlixBus, Itabus for as low as $31 (€25). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
16h 5m
Cheapest Price
$44 (€36)
FlixBus frequency
6 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Itabus

About
Itabus is a leading bus company in Italy, providing reliable and comfortable transportation services to its customers. Itabus operates a fleet of modern buses, ranging from luxury coaches to standard buses, all equipped with air conditioning, comfortable seating, and onboard entertainment.
Luggage & cancellation policy
Average Duration
20h 35m
Cheapest Price
$134 (€110)
Itabus frequency
1 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 20kg.
Additional luggage
5€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Dedicated seating areas; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.

FAQs: Bus from Siena to Palermo

Find answers to the most common questions about traveling from Siena to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Siena to Palermo can start from as little as $26 (€21) when you book in advance. The average bus ticket price for Siena to Palermo is $75 (€61); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Siena to Palermo is 16 h 10 min   to travel the 374 mile (603 km) long trip, with around there are 8 buses per day. Journey times can vary on weekends and holidays.
The first bus from Siena to Palermo leaves at 5: 00AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Siena to Palermo leaves at 11: 05PM.
Yes, it is possible to travel from Siena to Palermo without having to change trains with FlixBus. There is 1 direct bus from Siena to Palermo each day. There may be fewer direct services available on weekends or holidays.
For the route from Siena to Palermo you can take a bus with FlixBus or Itabus. Be sure to check out all possible bus providers that offer services to Palermo from Siena on Omio to compare what amenities they may have.
The cheapest month to travel from Siena to Palermo by bus is September.
You have options as you can travel from Siena to Palermo 4 different ways: train, bus, flight or ferry.
Yes, the following accessibility options are available when taking the bus from Siena to Palermo:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
  • Itabus
    • Assistance
    • Dedicated seating areas
    • Accessible restrooms.
Yes, there are bathrooms on board the bus from Siena to Palermo for bus providers FlixBus and Itabus.
Some of the most interesting sights to explore in Palermo are:
  • Palermo Cathedral, a stunning architectural blend of Norman, Moorish, and Baroque styles
  • Teatro Massimo, Italy's largest opera house known for its grand performances and impressive acoustics
  • Palazzo dei Normanni, a historic palace featuring the exquisite Palatine Chapel with its Byzantine mosaics
  • Quattro Canti, a Baroque square at the intersection of Palermo's two main streets, known for its symmetrical fountains and statues
  • Orto Botanico di Palermo, a lush botanical garden showcasing diverse plant species.
The best things to do in Palermo include:
  • Capuchin Catacombs, an eerie yet fascinating underground cemetery with mummified remains
  • Ballarò Market, a bustling street market offering a taste of local Sicilian produce and culture
  • Explore the vibrant street art in the Vucciria district
  • Take a cooking class to learn how to make traditional Sicilian dishes
  • Enjoy a leisurely stroll along the picturesque Foro Italico promenade.
Yes, bikes are allowed on board the bus with bus providers FlixBus and Itabus.
Whether you can cancel your bus ticket from Siena to Palermo depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
  • Itabus
    • You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.

To find the cheapest bus tickets for your trip from Siena to Palermo, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Siena to Palermo.
    Yes, the following luggage options are included when booking a bus ticket from Siena to Palermo:
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    • Itabus
      • One carry-on bag up to 10kg and one checked bag up to 20kg.
    Yes, the following additional luggage options are available when booking a bus ticket from Siena to Palermo:
    • FlixBus
      • Additional luggage can be purchased for a fee.
    • Itabus
      • 5€ per additional bag.
    Yes, you can bring your pet on the bus from Siena to Palermo. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    • Itabus
      • Small pets allowed in carriers
      • Larger pets must be leashed and muzzled.
    You can reserve your seat on the bus from Siena to Palermo with the following bus companies: FlixBus and Itabus
    Yes, there are USB plugs on board the bus from Siena to Palermo with the following bus providers: FlixBus and Itabus.
    Yes, there is Wifi on board the bus from Siena to Palermo with the following bus providers: FlixBus and Itabus.

    popular bus stations

    Popular bus stations from Siena to Palermo

    Siena
    Palermo
    Siena, Stazione FS (Piazzale Carlo Rosselli)
    information
    Siena, P.za Gramsc
    information
    Siena, Siena/Viale Pietro Toselli
    information
    Siena, Via Fiorentina 135/Stellino
    information

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