4.9
4.6The cheapest and fastest buses from Siena to Palermo
Cheapest price
$171
Average price
$175
Fastest journey
16 h 5 m
Average duration
19 h 1 m
Buses per day
4
Distance
603 km
The best way to find a cheap bus ticket from Siena to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Siena to Palermo will cost around $175 if you buy it on the day, but the cheapest tickets can be found for only $171.
Of the 4 buses that leave Siena for Palermo on Mon, Dec 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Dec 22 the direct buses cover the 603 km distance in an average of 19 h 1 m but if you time it right, some buses will get you there in just 16 h 5 m .
On Mon, Dec 22 the slowest buses will take 23 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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Travel Information
Compare train, bus, flight, and ferry for Siena to Palermo
Omio recommends booking the bus as it is the most popular option from Siena to Palermo among Omio's users. If you are prioritising price take the ferry with prices starting from €36. For those with little time consider booking a flight which can get you there in 1h 23m. The ticket price range depends on the travel mode: a ferry costs an average of €36, and a train costs an average of €82.
Distance: 374 miles (603 km)
Compare bus with
Most popular Bus | Flight | Train | Ferry |
|---|---|---|---|
€72 Average price | €109 Average price | €134 Average price | €51 Average price Cheapest |
16h 46m Average total duration 16h 16m Onboard + 30m Additional time* | 4h 23m Average total duration Fastest 1h 23m Onboard + 3h 0m Additional time* | 16h 37m Average total duration 16h 7m Onboard + 30m Additional time* | 20h 30m Average total duration 19h 30m Onboard + 1h 0m Additional time* |
Most popular bus company |  Most popular airline |  Most popular train company |  Most popular ferry company |
Direct Options | Direct Options | Direct Options | Direct Options |
Siena to Palermo Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar | Departure Time 11:40AM | Arrival Time 11:10PM | Duration 11h30 | Departure days Wed | Cheapest price $97 |
Operator FlixBus | Departure Time 11:55AM | Arrival Time 11:00AM | Duration 23h05 | Departure days Mon, Tue, Wed | Cheapest price $185 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 11:00AM | Duration 16h05 | Departure days Mon, Tue, Wed, Thu, Sun | Cheapest price $86 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 02:25PM | Duration 17h25 | Departure days Mon, Tue, Sun | Cheapest price $160 |
Live departures
Siena to Palermo bus times
The table below shows live departures for Siena to Palermo buses for today, Sunday, December 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 5:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 19h30 | 1:25 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
| FlixBus | 5:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 16h05 | 10:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 0 transfersDirect | |
| FlixBus · FlixBus | 8:00 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 17h25 | 1:25 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
| Monday, December 22 | |||||
| FlixBus · FlixBus · FlixBus | 10:55 AM Siena, Siena/Viale Pietro Toselli | 23h05 | 10:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Siena to Palermo by train, bus, flight, or ferry
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Siena to Palermo
ItalyItaly
Buses from Siena to Palermo run on average 6 times per day, taking around 16h 16m. Cheap bus tickets for this journey start at $43 (€34) but you can travel from only $31 (€25) by flight.
There are 1 buses per day. The earliest bus runs at 00:52, the last at 21:46. The fastest bus covers the 374 miles (603 km) distance in 16h 5m.
Distance 374 miles (603 km) |
Average bus duration 16h 16m |
Cheapest ticket price $43 (€34) |
Buses per day 6 |
Direct buses 1 |
Fastest bus 16h 5m |
First bus 00:52 |
Last bus 21:46 |
Bus providers: FlixBus, Itabus from Siena to PalermoYou can travel by bus between Siena to Palermo with FlixBus, Itabus for as low as $31 (€25). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
FAQs: Bus from Siena to Palermo
Find answers to the most common questions about traveling from Siena to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Palermo Cathedral, a stunning architectural blend of Norman, Moorish, and Baroque styles
- Teatro Massimo, Italy's largest opera house known for its grand performances and impressive acoustics
- Palazzo dei Normanni, a historic palace featuring the exquisite Palatine Chapel with its Byzantine mosaics
- Quattro Canti, a Baroque square at the intersection of Palermo's two main streets, known for its symmetrical fountains and statues
- Orto Botanico di Palermo, a lush botanical garden showcasing diverse plant species.
- Capuchin Catacombs, an eerie yet fascinating underground cemetery with mummified remains
- Ballarò Market, a bustling street market offering a taste of local Sicilian produce and culture
- Explore the vibrant street art in the Vucciria district
- Take a cooking class to learn how to make traditional Sicilian dishes
- Enjoy a leisurely stroll along the picturesque Foro Italico promenade.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
To find the cheapest bus tickets for your trip from Siena to Palermo, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- Larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Siena to Palermo
Most popular bus connections from Siena
More options for your journey from Siena to Palermo
Here are some other resources that might have the information you need
Most popular buses to and from Palermo and Siena
Most popular bus connections to Palermo
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