- Must visit
Palazzo Abatellis - Regional Gallery of Sicily
Major Sicilian art museum in a Gothic-Catalan palace, known for Antonello da Messina's masterpieces and medieval to Renaissance works.
Cheapest price
$168
Average price
$169
Fastest journey
20 h 15 m
Average duration
1 d 23 m
Buses per day
2
Distance
610 km
The best way to find a cheap bus ticket from Ancona to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Ancona to Palermo will cost around $169 if you buy it on the day, but the cheapest tickets can be found for only $168.
It's difficult to get from Ancona to Palermo without transferring at least 2 times.
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBusOmio recommends booking the train as it is the most popular option from Ancona to Palermo among Omio's users. If you are prioritising price take the bus with prices starting from $43. For those with little time consider booking a train which can get you there in 16h 42m. The ticket price range depends on the travel mode: a bus costs an average of $43, and a train costs an average of $52.
Distance: 379 miles (610 km)
| Bus | Most popular Train | Driving |
|---|---|---|
$97 Average price Cheapest | $121 Average price | $133 Average price (fuel + tolls) |
19h 15m Average total duration 18h 45m Onboard + 30m Additional time* | 17h 12m Average total duration Fastest 16h 42m Onboard + 30m Additional time* | 11h 42m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Ancona to Palermo:
A bus is $24 (€20) less than a train for this route with tickets for a train from Ancona to Palermo costing on average $121 (€98).
Other travel options to Palermo take longer:
Train takes on average 16h 42m.
Bus takes on average 18h 45m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:30AM | Arrival Time 11:00AM | Duration 28h30 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $95 |
Operator FlixBus | Departure Time 09:15AM | Arrival Time 11:00AM | Duration 25h45 | Departure days Sat, Sun | Cheapest price $127 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 11:00AM | Duration 20h15 | Departure days Everyday | Cheapest price $88 |
The table below shows live departures for Ancona to Palermo buses for today, Wednesday, June 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 6:30 AM Ancona, Piazza Rosselli (Stazione Ferroviaria) | 28h30 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 2:45 PM Ancona, Via Guglielmo Marconi / SS681 | 20h15 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Ancona to Palermo run on average 2 times per day, taking around 18h 45m. Cheap bus tickets for this journey start at $43 (€35) if you book in advance.
The earliest bus runs at 04:21, the last at 21:10. The fastest bus covers the 379 miles (610 km) distance in 20h 5m.
Distance 379 miles (610 km) |
Average bus duration 18h 45m |
Cheapest ticket price $43 (€35) |
Buses per day 2 |
Fastest bus 20h 5m |
First bus 4:21 AM |
Last bus 9:10 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 5 days |
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Major Sicilian art museum in a Gothic-Catalan palace, known for Antonello da Messina's masterpieces and medieval to Renaissance works.
Important archaeology museum with Phoenician, Greek, Roman and Egyptian collections, central for understanding Sicily's ancient history.
Well-preserved aristocratic house museum with original furnishings, frescoes and decorative arts, offering a vivid look at noble Palermo.
Palermo's famous seaside district with turquoise water, white sand and Liberty-style villas, highly popular with locals and visitors.
Lively historic market area known for street life, colorful stalls and an authentic atmosphere that draws many photographers.
Main pedestrian-friendly avenue cutting through the old center, lined with landmarks, shops and constant city energy.
Fried rice balls stuffed with ragù, butter, ham, cheese, or other fillings. A Palermo street-food icon and one of the city's most famous snacks.
Soft bread rolls filled with chickpea fritters, often served with lemon. A classic Palermo street food with deep local roots.
Also called pani câ meusa, this sesame roll is filled with chopped veal spleen and lung, often topped with caciocavallo or ricotta.
Established fine-dining restaurant offering modern interpretations of Sicilian cuisine, polished service, and a more upscale atmosphere.
Well-known restaurant near the historic center serving refined Sicilian cuisine in an elegant but relaxed atmosphere, with strong local ingredients.
Popular central spot known for approachable Sicilian dishes, pasta, and a lively casual atmosphere close to Quattro Canti.
Moderate by Italian standards. Street food and local trattorias are good value, while central hotels and upscale dining cost more.
Service is often included or covered by a coperto. Tipping is not mandatory, but leaving EUR 1-2 at cafes or 5-10% for very good restaurant service is appreciated. Round up taxis.
Find answers to the most common questions about traveling from Ancona to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

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