The cheapest and fastest buses from Ancona to Palermo
Cheapest price
$109
Average price
$160
Fastest journey
20 h 5 m
Average duration
23 h 58 m
Buses per day
4
Distance
610 km
The best way to find a cheap bus ticket from Ancona to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Ancona to Palermo will cost around $160 if you buy it on the day, but the cheapest tickets can be found for only $109.
Of the 4 buses that leave Ancona for Palermo on Thu, Dec 04, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Dec 04 the direct buses cover the 610 km distance in an average of 23 h 58 m but if you time it right, some buses will get you there in just 20 h 5 m .
On Thu, Dec 04 the slowest buses will take 1 d 4 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.








Travel Information
Compare train and bus for Ancona to Palermo
Omio recommends booking the train as it is the most popular option from Ancona to Palermo among Omio's users. If you are prioritising price take the bus with prices starting from €54. For those with little time consider booking a train which can get you there in 16h 36m. The ticket price range depends on the travel mode: a bus costs an average of €54, and a train costs an average of €57.
Distance: 379 miles (610 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€103 Average price Cheapest | €107 Average price |
19h 15m Average total duration 18h 45m Onboard + 30m Additional time* | 17h 6m Average total duration Fastest 16h 36m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Ancona to Palermo Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:30AM | Arrival Time 11:00AM | Duration 28h30 | Departure days Sat, Sun | Cheapest price $120 |
Operator FlixBus | Departure Time 09:15AM | Arrival Time 02:25PM | Duration 29h10 | Departure days Sat, Sun | Cheapest price $139 |
Operator FlixBus | Departure Time 10:30AM | Arrival Time 11:00AM | Duration 24h30 | Departure days Sat | Cheapest price $153 |
Operator FlixBus | Departure Time 02:40PM | Arrival Time 11:00AM | Duration 20h20 | Departure days Sat, Sun | Cheapest price $130 |
Live departures
Ancona to Palermo bus times
The table below shows live departures for Ancona to Palermo buses for tomorrow, Thursday, December 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:30 AM Ancona | 28h30 | 9:00 AM Palermo | 0 transfersDirect | |
![]() | 7:15 AM Ancona | 25h45 | 9:00 AM Palermo | 0 transfersDirect | |
![]() | 12:55 PM Ancona | 20h05 | 9:00 AM Palermo | 0 transfersDirect | |
![]() | 2:55 PM Ancona | 21h30 | 12:25 PM Palermo | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Ancona to Palermo by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 04
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Journey information
Overview: Bus from Ancona to Palermo
Buses from Ancona to Palermo run on average 3 times per day, taking around 18h 45m. Cheap bus tickets for this journey start at $68 (€54) if you book in advance.
The earliest bus runs at 04:21, the last at 19:05. The fastest bus covers the 379 miles (610 km) distance in 19h 25m.
Distance 379 miles (610 km) |
Average bus duration 18h 45m |
Cheapest ticket price $68 (€54) |
Buses per day 3 |
Fastest bus 19h 25m |
First bus 04:21 |
Last bus 19:05 |
Bus providers: FlixBus from Ancona to PalermoYou can travel by bus between Ancona to Palermo with FlixBus for as low as $68 (€54). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Ancona to Palermo
Find answers to the most common questions about traveling from Ancona to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Palermo Cathedral, a stunning architectural blend of Norman, Moorish, and Baroque styles
- Teatro Massimo, Italy's largest opera house known for its grand performances and impressive acoustics
- Palazzo dei Normanni, a historic palace featuring the exquisite Palatine Chapel with its Byzantine mosaics
- Quattro Canti, a Baroque square at the intersection of Palermo's two main streets, known for its symmetrical fountains and statues
- Orto Botanico di Palermo, a lush botanical garden showcasing diverse plant species.
- Capuchin Catacombs, an eerie yet fascinating underground cemetery with mummified remains
- Ballarò Market, a bustling street market offering a taste of local Sicilian produce and culture
- Explore the vibrant street art in the Vucciria district
- Take a cooking class to learn how to make traditional Sicilian dishes
- Enjoy a leisurely stroll along the picturesque Foro Italico promenade.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Ancona to Palermo, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
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Popular bus stations from Ancona to Palermo
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