- Must visit
Antonino Salinas Regional Archaeological Museum
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Cheapest price on Oct 20
€51
Average ticket price on Oct 20
€91
Fastest journey on Oct 20
20 h 15 m
Average journey duration on Oct 20
1 d 2 h 56 m
Buses on Oct 20
4
Distance
610 km
The best way to find a cheap bus ticket from Ancona to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Ancona to Palermo will cost around €91 if you buy it on the day, but the cheapest tickets can be found for only €51.
On Tue, Oct 20, we found 4 buses from Ancona to Palermo, including 4 direct services.
On Tue, Oct 20 the direct buses cover the 610 km distance in an average of 1 d 2 h 56 m but if you time it right, some buses will get you there in just 20 h 15 m .
On Tue, Oct 20 the slowest buses will take 1 d 6 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.








Buses from Ancona to Palermo run on average 3 times per day, taking around 19h 12m. Cheap bus tickets for this journey start at €57 but you can travel from only €51 by train.
The earliest bus runs at 04:21, the last at 21:10. The fastest bus covers the 379 miles (610 km) distance in 17h 5m.
Distance 379 miles (610 km) |
Average bus duration 19h 12m |
Cheapest ticket price €57 |
Buses per day 3 |
Fastest bus 17h 5m |
First bus 4:21 AM |
Last bus 9:10 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 1 day |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:30AM | Arrival Time 10:00AM | Duration 30h30 | Departure days Tue | Cheapest price €73 |
Operator FlixBus | Departure Time 04:30AM | Arrival Time 09:00AM | Duration 28h30 | Departure days Mon, Tue, Fri, Sat | Cheapest price €74 |
Operator FlixBus | Departure Time 05:30AM | Arrival Time 10:00AM | Duration 28h30 | Departure days Mon, Tue, Fri, Sat | Cheapest price €35 |
Operator FlixBus | Departure Time 06:30AM | Arrival Time 11:00AM | Duration 28h30 | Departure days Wed, Thu | Cheapest price €52 |
Operator FlixBus | Departure Time 08:15AM | Arrival Time 12:55PM | Duration 28h40 | Departure days Sat | Cheapest price €44 |
Operator FlixBus | Departure Time 09:15AM | Arrival Time 11:00AM | Duration 25h45 | Departure days Sun | Cheapest price €88 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 09:00AM | Duration 20h15 | Departure days Mon, Tue, Fri, Sat | Cheapest price €59 |
Operator FlixBus | Departure Time 01:45PM | Arrival Time 10:00AM | Duration 20h15 | Departure days Sat | Cheapest price €74 |
Operator FlixBus | Departure Time 01:55PM | Arrival Time 10:00AM | Duration 20h05 | Departure days Mon, Sat | Cheapest price €43 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 11:00AM | Duration 20h15 | Departure days Wed, Thu, Sun | Cheapest price €51 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 07:20PM | Duration 26h35 | Departure days Wed, Thu | Cheapest price €49 |
The table below shows live departures for Ancona to Palermo buses for tomorrow, Tuesday, October 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:30 AM Ancona | 30h30 | 10:00 AM Palermo | 0 transfersDirect | |
![]() | 4:30 AM Ancona | 28h30 | 9:00 AM Palermo | 0 transfersDirect | |
![]() | 5:30 AM Ancona | 28h30 | 10:00 AM Palermo | 0 transfersDirect | |
![]() | 12:45 PM Ancona | 20h15 | 9:00 AM Palermo | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Historic rooms and vivid majolica floors showcase aristocratic Palermo. Visit for decorative arts, period interiors and city history.
Housed in the grand Steri Palace, this museum presents the Sicilian Inquisition’s story through cells, graffiti and historical documents.
Palermo’s elegant main boulevard links major monuments, shops and theaters. Ideal for first walks and observing the city’s layered architecture.
This historic street cuts across the old center and hosts markets, churches and daily life. A lively route for exploring local Palermo.
A bustling old quarter famous for layered street life, churches and market culture. Best explored on foot for atmosphere and urban history.
Crisp fried rice ball stuffed with ragù, peas and caciocavallo. A Sicilian street food icon widely loved in Palermo.
Soft sesame-topped bun filled with spleen and lung, often with caciocavallo or ricotta. A classic Palermo street food with deep local roots.
Pasta with sardines, wild fennel, pine nuts and raisins. Its sweet-savory flavor reflects Palermo's Arab-Norman culinary heritage.
Refined Michelin-starred restaurant known for creative Sicilian tasting menus in an elegant, intimate setting.
Historic seafood restaurant near the port, praised for fresh catch, raw dishes and classic Palermo fish recipes.
Legendary no-frills street-food stop celebrated for pane con la milza and authentic local sandwiches loved by residents.
Moderate for Italy. Street food and local meals are affordable, while hotels in peak season cost more. Public transport is cheap, keeping overall tourist costs reasonable.
Service is often included or modest. Round up or leave 5-10% for great restaurant service. Taxis are usually rounded up. Small change is fine in cafes.
Find answers to the most common questions about traveling from Ancona to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

Most Ancona to Palermo buses use the Ancona, Via Guglielmo Marconi / SS681 to station pair. Use this guide to compare Ancona and Palermo bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need