- Must visit
Vatican Museums
One of the world's great museum complexes, home to vast papal collections and the Sistine Chapel. A priority visit for art, history, and Renaissance masterpieces.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Comiso to Rome
Showing times and prices for Jul 12
Cheapest price
$109
Average price
$124
Fastest journey
16 h 5 m
Average duration
18 h 35 m
Buses per day
2
Distance
579 km
Cheap tickets
The best way to find a cheap bus ticket from Comiso to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Comiso to Rome will cost around $124 if you buy it on the day, but the cheapest tickets can be found for only $109.
Fast buses
It's difficult to get from Comiso to Rome without transferring at least once.
FlixBus · FlixBus2:45 PM16h05Comiso, Via Ghandi (Fermata Sais Comiso)6:50 AMRoma, Autostazione Tiburtina$1091One-way1 transfer- FlixBus · FlixBus · FlixBus2:45 PM21h05Comiso, Via Ghandi (Fermata Sais Comiso)11:50 AMRoma, Autostazione (Metro Anagnina)$1391One-way2 transfers
- FlixBus · FlixBus2:45 PM16h05Comiso, Via Ghandi (Fermata Sais Comiso)6:50 AMRoma, Autostazione Tiburtina$1091One-way1 transfer
- FlixBus · FlixBus · FlixBus2:45 PM21h05Comiso, Via Ghandi (Fermata Sais Comiso)11:50 AMRoma, Autostazione (Metro Anagnina)$1391One-way2 transfers
Travel Information
Compare train, bus, and flight for Comiso to Rome
Omio recommends booking the flight as it is the most popular option from Comiso to Rome among Omio's users. If you are prioritising price take the flight with prices starting from $21. For those with little time consider booking a flight which can get you there in 1h 21m. The ticket price range depends on the travel mode: a flight costs an average of $21, and a train costs an average of $51.
Distance: 359 miles (579 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$87 Average price | $74 Average price Cheapest | $101 Average price |
13h 12m Average total duration 12h 42m Onboard + 30m Additional time* | 4h 21m Average total duration Fastest 1h 21m Onboard + 3h 0m Additional time* | 14h 46m Average total duration 14h 16m Onboard + 30m Additional time* |
Most popular bus company |  Most popular airline |  Most popular train company |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Comiso to Rome is a flight with an average price of $74 (€61).
This is compared to other travel options from Comiso to Rome:
A flight is $12 (€10) less than a bus for this route with tickets for a bus from Comiso to Rome costing on average $87 (€71).
A flight is $27 (€22) less than a train for this route with tickets for a train from Comiso to Rome costing on average $101 (€83).
The fastest way to travel from Comiso to Rome is by flight with an average journey time of 1h 21m.
Other travel options to Rome take longer:
Bus takes on average 12h 42m.
Train takes on average 14h 16m.
It's helpful to compare your options as there are 3 ways to travel between Comiso and Rome including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Comiso to Rome among Omio's users.
Comiso to Rome Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:45PM | Arrival Time 06:50AM | Duration 16h05 | Departure days Everyday | Cheapest price $80 |
Live departures
Comiso to Rome bus times
The table below shows live departures for Comiso to Rome buses for tomorrow, Sunday, July 12. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 2:45 PM Comiso, Via Ghandi (Fermata Sais Comiso) | 16h05 | 6:50 AM Roma, Autostazione Tiburtina | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 2:45 PM Comiso, Via Ghandi (Fermata Sais Comiso) | 21h05 | 11:50 AM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Comiso to Rome by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sun
Jul 12
Jul 12
Mon
Jul 13
Jul 13
Tue
Jul 14
Jul 14
Wed
Jul 15
Jul 15
Thu
Jul 16
Jul 16
Fri
Jul 17
Jul 17
Sat
Jul 18
Jul 18
Sun
Jul 19
Jul 19
Mon
Jul 20
Jul 20
Tue
Jul 21
Jul 21
Wed
Jul 22
Jul 22
Thu
Jul 23
Jul 23
Fri
Jul 24
Jul 24
Sat
Jul 25
Jul 25
Sun
Jul 26
Jul 26
Mon
Jul 27
Jul 27
Tue
Jul 28
Jul 28
Wed
Jul 29
Jul 29
Thu
Jul 30
Jul 30
Fri
Jul 31
Jul 31
Sat
Aug 01
Aug 01
Why should you book Comiso to Rome buses with Omio?
FlixBus as well as Azienda Siciliana Trasporti offer buses services from Comiso to Rome.
Omio is an official ticket reseller for all your travel options from Comiso to Rome.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Azienda Siciliana Trasporti to find the best option for your trip from Comiso to Rome.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Comiso to Rome.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Comiso to Rome.
Journey information
Overview: Bus from Comiso to Rome
ItalyItaly
Buses from Comiso to Rome run on average 2 times per day, taking around 12h 42m. Cheap bus tickets for this journey start at $27 (€22) but you can travel from only $21 (€17) by flight.
The earliest bus runs at 05:14, the last at 23:30. The fastest bus covers the 359 miles (579 km) distance in 16h 5m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $21 (€17)
Distance 359 miles (579 km) |
Average bus duration 12h 42m |
Cheapest ticket price $27 (€22) |
Buses per day 2 |
Fastest bus 16h 5m |
First bus 5:14 AM |
Last bus 11:30 PM |
Cheapest Month Jul |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Thu |
Least Busy Day Sat |
Best time to book 1 day |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $21 (€17)
Bus providers: FlixBus, BlaBlaCar, Azienda Siciliana Trasporti from Comiso to RomeYou can travel by bus between Comiso to Rome with FlixBus, BlaBlaCar, Azienda Siciliana Trasporti for as low as $21 (€17). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
16h 5m
Cheapest Price
$27 (€22)
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
BlaBlaCar
About
BlaBlaCar is a French online marketplace for carpooling, connecting drivers with empty seats and passengers traveling to the same destination to share costs. Founded in 2006, it operates in Europe and Latin America, boasting 26 million active members. The platform also includes BlaBlaCar Bus, an intercity bus service. BlaBlaCar's name comes from its rating system for drivers' chattiness: "Bla" for quiet, "BlaBla" for talkative, and "BlaBlaBla" for very chatty. The company aims to be the leading marketplace for shared travel, offering affordable and sustainable solutions by combining carpooling with bus journeys.
Luggage & cancellation policy
BlaBlaCar frequency
1 a day
Azienda Siciliana Trasporti
Luggage & cancellation policy
Average Duration
13h 50m
Azienda Siciliana Trasporti frequency
1 a day
Complete guide to Rome
Things to do in Rome
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
- Must visit
Galleria Borghese
A superb villa museum with Bernini sculptures and major paintings by Caravaggio, Raphael, and Titian. Timed entry is essential due to limited capacity.
- Recommended
Capitoline Museums
The city's historic civic museums on Capitoline Hill, known for classical sculpture, ancient Roman art, and excellent views over the Forum.
- Must visit
Piazza Navona
A lively Baroque square with monumental fountains, elegant facades, and one of the most recognizable urban spaces in Rome.
- Must visit
Spanish Steps
A famous stairway and gathering point linking Piazza di Spagna with Trinita dei Monti, especially popular for photos and central city strolls.
- Must visit
Trastevere
A beloved neighborhood of narrow lanes, ivy-covered buildings, and lively Roman atmosphere, ideal for wandering day or night.
- Vegetarian
Cacio e Pepe
A classic Roman pasta with pecorino Romano, black pepper, and pasta water. It is one of the city’s most iconic dishes for its simplicity and bold flavor.
Carbonara
Traditional Roman pasta made with guanciale, egg yolk, pecorino Romano, and black pepper. It is a defining dish of Rome and is famously made without cream.
Amatriciana
A beloved pasta sauce of tomato, guanciale, pecorino Romano, and chili. Though linked to Amatrice, it is deeply rooted in Roman trattoria cooking.
La Pergola
Rome’s best-known luxury fine-dining restaurant, famous for panoramic views, elegant service, and sophisticated Italian cuisine.
Armando Al Pantheon
A historic restaurant near the Pantheon serving refined Roman classics with strong local identity. Well known for seasonal specialties and pasta.
Roscioli Salumeria Con Cucina
A celebrated central Rome dining room known for Roman pasta, cured meats, and an exceptional wine list. Lively, polished, and very popular.
Euro
Moderate for Western Europe. Sights and central hotels cost more, but food, coffee, and transit can be good value.
Average meal costs
- Budget
- EUR 8-15 for pizza, panini, or takeaway.
- Mid-range
- EUR 20-40 per person at a casual restaurant.
- Fine dining
- EUR 80+ per person at upscale restaurants.
- Coffee
- EUR 1.20-2.50 for espresso or cappuccino.
Tipping culture
Service is often included or modest. Locals may round up or leave EUR 1-2 at cafes; 5-10% is appreciated at restaurants for good service, not obligatory. Round up taxis.
TicketAppy
Get the appOfficial public transport app
Prices
- Single ticket
- EUR 1.50
- Day pass
- EUR 7.00
To the city center
Rome, Via Marsala / Viale Enrico De Nicola, Rome -> Rome Termini
- Distance
- 0.3 km
- Travel time
- 4 min
- BIT single tickets are valid for 100 min on buses, trams, metro, and urban rail, with one metro entry included.
- Onboard card payment is not generally available on Rome buses and trams, so buy and validate tickets in advance or use contactless where enabled in metro and selected services.
FAQs: Bus from Comiso to Rome
Find answers to the most common questions about traveling from Comiso to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Comiso to Rome can start from as little as $27 (€22) when you book in advance. The average bus ticket price for Comiso to Rome is $87 (€71) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Comiso to Rome is 16h 5m to travel the 359 miles (579 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Comiso to Rome leaves at 5:14 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Comiso to Rome leaves at 11:30 PM.
There are 2 buses a day from Comiso to Rome which require at least one change with FlixBus, BlaBlaCar, Azienda Siciliana Trasporti. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Comiso to Rome, you can count on FlixBus, BlaBlaCar, Azienda Siciliana Trasporti for the best way to get you to Rome. You can also check all possible bus companies who offer a service between Comiso and Rome and compare the amenities they offer before buying a bus ticket.
A trip to Rome from Comiso is worth doing but not as a day trip with a journey time of 16h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Comiso to Rome is July.
It's helpful to compare your options as there are 3 ways to travel between Comiso and Rome including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Comiso to Rome:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Comiso to Rome for bus company FlixBus.
Some of the most interesting sights to explore in Rome are:
- Colosseum, an ancient amphitheater known for its gladiatorial contests and iconic architecture
- Vatican Museums, a vast collection of art and historical artifacts including the Sistine Chapel
- Roman Forum, the ruins of ancient Rome's center for public life and government
- Pantheon, a well-preserved Roman temple with a striking dome and oculus
- Trevi Fountain, a famous Baroque fountain where visitors traditionally toss coins for good luck.
The best things to do in Rome include:
- Explore Trastevere, a charming neighborhood with narrow streets and vibrant nightlife
- Take a stroll through Villa Borghese, a beautiful park with museums and gardens
- Enjoy a gelato at Piazza Navona, a lively square with fountains and street artists
- Visit the Spanish Steps, a popular spot for people-watching and enjoying the view
- Discover the Catacombs, ancient underground burial sites with guided tours.
Whether you can cancel your bus ticket from Comiso to Rome depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Comiso to Rome.
Yes, the following luggage options are included when booking a bus ticket from Comiso to Rome:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Comiso to Rome:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Comiso to Rome. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Comiso to Rome with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Comiso to Rome with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Comiso to Rome with the following bus company: FlixBus.
Since both Comiso and Rome are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Comiso to Rome among Omio's users.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Rome, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, major landmarks, and popular squares. Common scams include unofficial taxi drivers overcharging and street vendors selling counterfeit goods. It's advisable to use authorized taxis, keep valuables secure, and be wary of distraction techniques used by scammers in busy tourist spots.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
More options for your journey from Comiso to Rome
Here are some other resources that might have the information you need
Most popular buses to and from Rome and Comiso
Most popular bus connections to Rome
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
