The cheapest and fastest buses from Comiso to Rome
Cheapest price
$118
Average price
$128
Fastest journey
16 h 35 m
Average duration
18 h 53 m
Buses per day
2
Distance
579 km
The best way to find a cheap bus ticket from Comiso to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Comiso to Rome will cost around $128 if you buy it on the day, but the cheapest tickets can be found for only $118.
It's difficult to get from Comiso to Rome without transferring at least 2 times.
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBusTravel Information
Compare train, bus, and flight for Comiso to Rome
Omio recommends booking the flight as it is the most popular option from Comiso to Rome among Omio's users. If you are prioritising price take the bus with prices starting from €40. For those with little time consider booking a flight which can get you there in 1h 15m. The ticket price range depends on the travel mode: a bus costs an average of €40, and a flight costs an average of €27.
Distance: 359 miles (579 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€90 Average price Cheapest | €128 Average price | €96 Average price |
13h 12m Average total duration 12h 42m Onboard + 30m Additional time* | 4h 15m Average total duration Fastest 1h 15m Onboard + 3h 0m Additional time* | 14h 53m Average total duration 14h 23m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Comiso to Rome Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:30PM | Arrival Time 07:05AM | Duration 16h35 | Departure days Wed, Thu, Fri, Sat | Cheapest price $70 |
Live departures
Comiso to Rome bus times
The table below shows live departures for Comiso to Rome buses for today, Wednesday, November 26. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 1:30 PM Comiso, Via Ghandi (Fermata Sais Comiso) | 17h40 | 7:10 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:30 PM Comiso, Via Ghandi (Fermata Sais Comiso) | 22h00 | 11:30 AM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Comiso to Rome by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 27
Nov 28
Nov 29
Nov 30
Dec 01
Dec 02
Dec 03
Journey information
Overview: Bus from Comiso to Rome
Buses from Comiso to Rome run on average 2 times per day, taking around 12h 42m. Cheap bus tickets for this journey start at $50 (€40) but you can travel from only $33 (€27) by flight.
The earliest bus runs at 04:50, the last at 23:28. The fastest bus covers the 359 miles (579 km) distance in 16h 30m.
Distance 359 miles (579 km) |
Average bus duration 12h 42m |
Cheapest ticket price $50 (€40) |
Buses per day 2 |
Fastest bus 16h 30m |
First bus 04:50 |
Last bus 23:28 |
Bus providers: FlixBus, BlaBlaCar, Azienda Siciliana Trasporti from Comiso to RomeYou can travel by bus between Comiso to Rome with FlixBus, BlaBlaCar, Azienda Siciliana Trasporti for as low as $33 (€27). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar
Azienda Siciliana Trasporti
FAQs: Bus from Comiso to Rome
Find answers to the most common questions about traveling from Comiso to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Colosseum, an ancient amphitheater known for its gladiatorial contests and iconic architecture
- Vatican Museums, a vast collection of art and historical artifacts including the Sistine Chapel
- Roman Forum, the ruins of ancient Rome's center for public life and government
- Pantheon, a well-preserved Roman temple with a striking dome and oculus
- Trevi Fountain, a famous Baroque fountain where visitors traditionally toss coins for good luck.
- Explore Trastevere, a charming neighborhood with narrow streets and vibrant nightlife
- Take a stroll through Villa Borghese, a beautiful park with museums and gardens
- Enjoy a gelato at Piazza Navona, a lively square with fountains and street artists
- Visit the Spanish Steps, a popular spot for people-watching and enjoying the view
- Discover the Catacombs, ancient underground burial sites with guided tours.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Comiso to Rome, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
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Popular bus stations from Comiso to Rome
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