Travel Information
Compare train and bus for Comiso to Palermo
Omio recommends booking the train as it is the most popular option from Comiso to Palermo among Omio's users. If you are prioritising price take the train with prices starting from €18. For those with little time consider booking a bus which can get you there in 3h 48m. The ticket price range depends on the travel mode: a train costs an average of €18, and a bus costs an average of €19.
Distance: 105 miles (170 km)
Compare train with
Most popular Train | Bus |
|---|---|
€20 Average price Cheapest | €20 Average price |
4h 20m Average total duration 3h 50m Onboard + 30m Additional time* | 4h 18m Average total duration Fastest 3h 48m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
This is compared to other travel options from Comiso to Palermo:
A train is €0.14 less than a bus for this route with tickets for a bus from Comiso to Palermo costing on average €20.
Other travel options to Palermo take longer:
Train takes on average 3h 50m.
Travel optionsfrom Comiso to Palermo
How to get from Comiso to Palermo by train, bus or flight.
Our recommendation
The best way to travel from Comiso to Palermo is by taking a train because it’s the best combination of price and speed.
Regionale 5466 · treno 5503 effettuato con bus PA3256:33 AM4h25Comiso station10:58 AMPalermo Centrale€191One-way1 transfer
Cheapest
Regionale 5466 · treno 5503 effettuato con bus PA3256:33 AM4h25Comiso station10:58 AMPalermo Centrale€191One-way1 transfer
Fastest
Regionale 5466 · treno 5503 effettuato con bus PA3256:33 AM4h25Comiso station10:58 AMPalermo Centrale€191One-way1 transfer
Other options
Regionale 5468 · treno 5491 effettuato con bus PA3278:30 AM4h28Comiso station12:58 PMPalermo Centrale€191One-way1 transfer
2490 · 24876:40 AM4h50Comiso, Via Ghandi (Fermata Sais Comiso)11:30 AMPalermo, Oreto - Orsi€191One-way1 transfer
2490 · 24876:40 AM4h55Comiso, Via Ghandi (Fermata Sais Comiso)11:35 AMPalermo, Via Tommaso Fazello (Terminal Bus)€191One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Comiso to Palermo
Travel to Palermo easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Comiso to Palermo.

This is compared to other travel options from Comiso to Palermo:
A train is €0.14 less than a bus for this route with tickets for a bus from Comiso to Palermo costing on average €20.
Other travel options to Palermo take longer:
Train takes on average 3h 50m.
- Around 4 buses per day.
- Around 4 trains per day.
However, we recommend checking specific travel dates for your route between Comiso and Palermo as scheduled services by train and bus can vary by season or day of the week.
- Buses mostly depart from Comiso, Via Ghandi (Fermata Sais Comiso) and arrive in Palermo, Via Tommaso Fazello (Terminal Bus).
- Trains mostly depart from Comiso station and arrive in Palermo Centrale.
- Ferries mostly depart from Port of Milazzo and arrive in Port of Palermo.
- Travel with BlaBlaCar, Azienda Siciliana Trasporti to go to Palermo by bus.
- Travel with Regionale to go to Palermo by train.
- 0 direct buses per day with BlaBlaCar, Azienda Siciliana Trasporti.
Travelling from Comiso to Palermo: related information
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