- Must visit
Palazzo Abatellis - Regional Gallery of Sicily
Major art museum in a Gothic-Catalan palace, known for Sicilian medieval and Renaissance masterpieces including works by Antonello da Messina.
Cheapest price
$68
Average price
$117
Fastest journey
1 d 6 h 40 m
Average duration
1 d 12 h 17 m
Buses per day
3
Distance
841 km
The best way to find a cheap bus ticket from Vicenza to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Vicenza to Palermo will cost around $117 if you buy it on the day, but the cheapest tickets can be found for only $68.
Of the 3 buses that leave Vicenza for Palermo on Sat, Jun 20, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 20 the direct buses cover the 841 km distance in an average of 1 d 12 h 17 m but if you time it right, some buses will get you there in just 1 d 6 h 40 m .
On Sat, Jun 20 the slowest buses will take 1 d 15 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Omio recommends booking the flight as it is the most popular option from Vicenza to Palermo among Omio's users. If you are prioritising price take the flight with prices starting from $21. For those with little time consider booking a flight which can get you there in 1h 50m. The ticket price range depends on the travel mode: a flight costs an average of $21, and a train costs an average of $71.
Distance: 522 miles (841 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$105 Average price | $75 Average price Cheapest | $150 Average price | $148 Average price (fuel + tolls) |
25h 49m Average total duration 25h 19m Onboard + 30m Additional time* | 4h 50m Average total duration Fastest 1h 50m Onboard + 3h 0m Additional time* | 18h 57m Average total duration 18h 27m Onboard + 30m Additional time* | 14h 22m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Vicenza to Palermo:
A flight is $30 (€25) less than a bus for this route with tickets for a bus from Vicenza to Palermo costing on average $105 (€86).
A flight is $75 (€62) less than a train for this route with tickets for a train from Vicenza to Palermo costing on average $150 (€123).
Other travel options to Palermo take longer:
Train takes on average 18h 27m.
Bus takes on average 25h 19m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:25AM | Arrival Time 09:00AM | Duration 27h35 | Departure days Sun | Cheapest price $113 |
Operator FlixBus | Departure Time 06:20AM | Arrival Time 10:00AM | Duration 27h40 | Departure days Tue | Cheapest price $105 |
Operator FlixBus | Departure Time 06:45AM | Arrival Time 10:00AM | Duration 27h15 | Departure days Mon, Thu | Cheapest price $94 |
Operator FlixBus | Departure Time 07:25AM | Arrival Time 11:00AM | Duration 27h35 | Departure days Fri | Cheapest price $223 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 05:20PM | Duration 30h40 | Departure days Tue, Sat | Cheapest price $95 |
Operator FlixBus | Departure Time 10:45AM | Arrival Time 03:15PM | Duration 28h30 | Departure days Fri | Cheapest price $217 |
Operator FlixBus | Departure Time 12:40PM | Arrival Time 07:20PM | Duration 30h40 | Departure days Fri | Cheapest price $231 |
Operator FlixBus | Departure Time 05:55PM | Arrival Time 09:00AM | Duration 39h05 | Departure days Tue, Sat | Cheapest price $110 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 10:00AM | Duration 39h05 | Departure days Mon, Tue, Sat | Cheapest price $56 |
The table below shows live departures for Vicenza to Palermo buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 7:25 AM Vicenza, Autostazione | 27h35 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:45 AM Vicenza, Autostazione | 28h30 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:40 PM Vicenza, Autostazione | 30h40 | 7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Vicenza to Palermo run on average 4 times per day, taking around 25h 19m. Cheap bus tickets for this journey start at $52 (€43) but you can travel from only $21 (€17) by flight.
The earliest bus runs at 01:01, the last at 21:10. The fastest bus covers the 522 miles (841 km) distance in 27h 15m.
Distance 522 miles (841 km) |
Average bus duration 25h 19m |
Cheapest ticket price $52 (€43) |
Buses per day 4 |
Fastest bus 27h 15m |
First bus 1:01 AM |
Last bus 9:10 PM |
Cheapest Month Mar |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 1 day |
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Major art museum in a Gothic-Catalan palace, known for Sicilian medieval and Renaissance masterpieces including works by Antonello da Messina.
One of Sicily's most important archaeological museums, with Punic, Greek and Roman collections and notable sculpture fragments.
Historic noble residence preserved with original furnishings, offering a vivid look at aristocratic life in Palermo.
Energetic historic district centered on Palermo's most famous street market, full of everyday local life and vivid street scenes.
Striking central square framed by historic buildings and the famous fountain, a key stop in the old town.
One of Palermo's main historic streets, largely pedestrianized and lined with landmarks, shops and lively urban scenes.
Fried rice balls stuffed with ragù, mozzarella, or butter and ham. Palermo is famous for its round arancine and strong street-food tradition.
A classic Palermo street sandwich made with veal spleen and lung, often topped with caciocavallo or ricotta. It is one of the city's most iconic local bites.
Chickpea fritters, usually served in a sesame bread roll. They are a beloved Palermo snack and a staple of the city's historic friggitorie.
Well-regarded restaurant near the historic center serving refined Sicilian cuisine with local ingredients in an elegant but relaxed atmosphere.
Popular central spot for approachable Sicilian cooking, including pasta and regional classics, with a casual and lively atmosphere.
Established seafood-focused trattoria appreciated for traditional Palermo and Sicilian dishes in a classic local dining room.
Moderate by Italian standards: street food is cheap, while central hotels and tourist restaurants cost more.
Service is often included or minimal. Rounding up or leaving EUR 1-2 at cafes is common; about 5-10% for very good restaurant service. Taxis are usually rounded up.
Find answers to the most common questions about traveling from Vicenza to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

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