- Must visit
Antonino Salinas Regional Archaeological Museum
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Cheapest price
€46
Average price
€84
Fastest journey
1 d 3 h 40 m
Average duration
1 d 10 h 8 m
Buses per day
4
Distance
841 km
The best way to find a cheap bus ticket from Vicenza to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Vicenza to Palermo will cost around €84 if you buy it on the day, but the cheapest tickets can be found for only €46.
Of the 4 buses that leave Vicenza for Palermo on Tue, Aug 04, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Aug 04 the direct buses cover the 841 km distance in an average of 1 d 10 h 8 m but if you time it right, some buses will get you there in just 1 d 3 h 40 m .
On Tue, Aug 04 the slowest buses will take 1 d 15 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.








Omio recommends booking the flight as it is the most popular option from Vicenza to Palermo among Omio's users. If you are prioritising price take the flight with prices starting from €17. For those with little time consider booking a flight which can get you there in 1h 50m. The ticket price range depends on the travel mode: a flight costs an average of €17, and a train costs an average of €58.
Distance: 522 miles (841 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
€86 Average price | €61 Average price Cheapest | €123 Average price | €121 Average price (fuel + tolls) |
25h 49m Average total duration 25h 19m Onboard + 30m Additional time* | 4h 50m Average total duration Fastest 1h 50m Onboard + 3h 0m Additional time* | 18h 57m Average total duration 18h 27m Onboard + 30m Additional time* | 14h 22m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Vicenza to Palermo:
A flight is €25 less than a bus for this route with tickets for a bus from Vicenza to Palermo costing on average €86.
A flight is €62 less than a train for this route with tickets for a train from Vicenza to Palermo costing on average €123.
Other travel options to Palermo take longer:
Train takes on average 18h 27m.
Bus takes on average 25h 19m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:20AM | Arrival Time 09:00AM | Duration 27h40 | Departure days Fri | Cheapest price €68 |
Operator FlixBus | Departure Time 05:25AM | Arrival Time 09:00AM | Duration 27h35 | Departure days Fri | Cheapest price €167 |
Operator FlixBus | Departure Time 06:20AM | Arrival Time 10:00AM | Duration 27h40 | Departure days Tue | Cheapest price €86 |
Operator FlixBus | Departure Time 06:45AM | Arrival Time 10:00AM | Duration 27h15 | Departure days Mon, Thu, Fri | Cheapest price €43 |
Operator FlixBus | Departure Time 07:25AM | Arrival Time 11:00AM | Duration 27h35 | Departure days Sun | Cheapest price €199 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 05:20PM | Duration 30h40 | Departure days Tue, Sat | Cheapest price €77 |
Operator FlixBus | Departure Time 10:45AM | Arrival Time 03:15PM | Duration 28h30 | Departure days Sun | Cheapest price €183 |
Operator FlixBus | Departure Time 12:40PM | Arrival Time 07:20PM | Duration 30h40 | Departure days Sun | Cheapest price €220 |
Operator FlixBus | Departure Time 05:55PM | Arrival Time 09:00AM | Duration 39h05 | Departure days Tue, Sat | Cheapest price €90 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 10:00AM | Duration 39h05 | Departure days Mon, Tue, Sat | Cheapest price €46 |
The table below shows live departures for Vicenza to Palermo buses for today, Monday, August 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:55 PM Vicenza | 39h05 | 10:00 AM Palermo | 0 transfersDirect | |
| Tuesday, August 4 | |||||
![]() | 6:20 AM Vicenza | 27h40 | 10:00 AM Palermo | 0 transfersDirect | |
![]() | 10:40 AM Vicenza | 30h40 | 5:20 PM Palermo | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Vicenza to Palermo run on average 4 times per day, taking around 25h 19m. Cheap bus tickets for this journey start at €43 but you can travel from only €17 by flight.
The earliest bus runs at 01:01, the last at 21:10. The fastest bus covers the 522 miles (841 km) distance in 27h 15m.
Distance 522 miles (841 km) |
Average bus duration 25h 19m |
Cheapest ticket price €43 |
Buses per day 4 |
Fastest bus 27h 15m |
First bus 1:01 AM |
Last bus 9:10 PM |
Cheapest Month Mar |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 1 day |
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Historic rooms and vivid majolica floors showcase aristocratic Palermo. Visit for decorative arts, period interiors and city history.
Housed in the grand Steri Palace, this museum presents the Sicilian Inquisition’s story through cells, graffiti and historical documents.
Palermo’s elegant main boulevard links major monuments, shops and theaters. Ideal for first walks and observing the city’s layered architecture.
This historic street cuts across the old center and hosts markets, churches and daily life. A lively route for exploring local Palermo.
A bustling old quarter famous for layered street life, churches and market culture. Best explored on foot for atmosphere and urban history.
Crisp fried rice ball stuffed with ragù, peas and caciocavallo. A Sicilian street food icon widely loved in Palermo.
Soft sesame-topped bun filled with spleen and lung, often with caciocavallo or ricotta. A classic Palermo street food with deep local roots.
Pasta with sardines, wild fennel, pine nuts and raisins. Its sweet-savory flavor reflects Palermo's Arab-Norman culinary heritage.
Refined Michelin-starred restaurant known for creative Sicilian tasting menus in an elegant, intimate setting.
Historic seafood restaurant near the port, praised for fresh catch, raw dishes and classic Palermo fish recipes.
Legendary no-frills street-food stop celebrated for pane con la milza and authentic local sandwiches loved by residents.
Moderate for Italy. Street food and local meals are affordable, while hotels in peak season cost more. Public transport is cheap, keeping overall tourist costs reasonable.
Service is often included or modest. Round up or leave 5-10% for great restaurant service. Taxis are usually rounded up. Small change is fine in cafes.
Find answers to the most common questions about traveling from Vicenza to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

Most Vicenza to Palermo buses use the Vicenza, Autostazione to Palermo, Via Tommaso Fazello (Terminal Bus) station pair. Use this guide to compare Vicenza and Palermo bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need