- Must visit
Antonino Salinas Regional Archaeological Museum
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Cheapest price on Sep 18
$112
Average ticket price on Sep 18
$142
Fastest journey on Sep 18
1 d 3 h 35 m
Average journey duration on Sep 18
1 d 4 h 55 m
Buses on Sep 18
3
Distance
841 km
The best way to find a cheap bus ticket from Vicenza to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Vicenza to Palermo will cost around $142 if you buy it on the day, but the cheapest tickets can be found for only $112.
It's difficult to get from Vicenza to Palermo without transferring at least once.
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FlixBus · FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Vicenza to Palermo among Omio's users. If you are prioritising price, take the train, with an average ticket price of $47 For those with little time, consider booking a flight, which has an average total journey time of 5h 6m. Average ticket prices depend on the travel mode: a train costs an average of $47, while a flight costs an average of $330.
Distance: 522 miles (841 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$196 Average price | $330 Average price | $47 Average price Cheapest | $149 Average price (fuel + tolls) |
25h 9m Average total duration 24h 39m Onboard + 30m Additional time* | 5h 6m Average total duration Fastest 3h 6m Onboard + 2h 0m Additional time* | 17h 52m Average total duration 17h 22m Onboard + 30m Additional time* | 14h 22m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Vicenza to Palermo:
A train is $149 less than a bus for this route with tickets for a bus from Vicenza to Palermo costing on average $196.
A train is $282 less than a flight for this route with tickets for a flight from Vicenza to Palermo costing on average $330.
Other travel options to Palermo take longer:
Train takes on average 17h 22m.
Bus takes on average 24h 39m.
Tickets start at around $196 compared to roughly $149 in fuel and tolls — a saving of about $-47.89. The journey takes 24h 39m versus 14h 22m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:25AM | Arrival Time 09:00AM | Duration 27h35 | Departure days Sun | Cheapest price $113 |
Operator FlixBus | Departure Time 06:20AM | Arrival Time 10:00AM | Duration 27h40 | Departure days Tue | Cheapest price $105 |
Operator FlixBus | Departure Time 06:45AM | Arrival Time 10:00AM | Duration 27h15 | Departure days Mon, Thu | Cheapest price $94 |
Operator FlixBus | Departure Time 07:25AM | Arrival Time 11:00AM | Duration 27h35 | Departure days Fri, Sat | Cheapest price $77 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 05:20PM | Duration 30h40 | Departure days Tue | Cheapest price $95 |
Operator FlixBus | Departure Time 10:45AM | Arrival Time 03:15PM | Duration 28h30 | Departure days Fri, Sat | Cheapest price $93 |
Operator FlixBus | Departure Time 12:40PM | Arrival Time 07:20PM | Duration 30h40 | Departure days Fri, Sat | Cheapest price $81 |
Operator FlixBus | Departure Time 05:55PM | Arrival Time 09:00AM | Duration 39h05 | Departure days Tue | Cheapest price $155 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 10:00AM | Duration 39h05 | Departure days Mon, Tue | Cheapest price $56 |
The table below shows live departures for Vicenza to Palermo buses for tomorrow, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 7:25 AM Vicenza, Autostazione | 27h35 | 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:45 AM Vicenza, Autostazione | 28h30 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:40 PM Vicenza, Autostazione | 30h40 | 7:20 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Vicenza to Palermo run on average 2 times per day, taking around 24h 39m. Cheap bus tickets for this journey start at $103 but you can travel from only $6 by train.
The earliest bus runs at 01:01, the last at 21:10. The fastest bus covers the 522 miles (841 km) distance in 20h 50m.
Distance 522 miles (841 km) |
Average bus duration 24h 39m |
Cheapest ticket price $103 |
Buses per day 2 |
Fastest bus 20h 50m |
First bus 1:01 AM |
Last bus 9:10 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 1 day |
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Historic rooms and vivid majolica floors showcase aristocratic Palermo. Visit for decorative arts, period interiors and city history.
Housed in the grand Steri Palace, this museum presents the Sicilian Inquisition’s story through cells, graffiti and historical documents.
Palermo’s elegant main boulevard links major monuments, shops and theaters. Ideal for first walks and observing the city’s layered architecture.
This historic street cuts across the old center and hosts markets, churches and daily life. A lively route for exploring local Palermo.
A bustling old quarter famous for layered street life, churches and market culture. Best explored on foot for atmosphere and urban history.
Crisp fried rice ball stuffed with ragù, peas and caciocavallo. A Sicilian street food icon widely loved in Palermo.
Soft sesame-topped bun filled with spleen and lung, often with caciocavallo or ricotta. A classic Palermo street food with deep local roots.
Pasta with sardines, wild fennel, pine nuts and raisins. Its sweet-savory flavor reflects Palermo's Arab-Norman culinary heritage.
Refined Michelin-starred restaurant known for creative Sicilian tasting menus in an elegant, intimate setting.
Historic seafood restaurant near the port, praised for fresh catch, raw dishes and classic Palermo fish recipes.
Legendary no-frills street-food stop celebrated for pane con la milza and authentic local sandwiches loved by residents.
Moderate for Italy. Street food and local meals are affordable, while hotels in peak season cost more. Public transport is cheap, keeping overall tourist costs reasonable.
Service is often included or modest. Round up or leave 5-10% for great restaurant service. Taxis are usually rounded up. Small change is fine in cafes.
Find answers to the most common questions about traveling from Vicenza to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

Most Vicenza to Palermo buses use the Vicenza, Autostazione to Palermo, Via Tommaso Fazello (Terminal Bus) station pair. Use this guide to compare Vicenza and Palermo bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need