Chicago, IL to South San Francisco, CA bus

Thu, Apr 02
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Costa Verde
Rede Expressos
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Costa Verde
Rede Expressos
2,000+ travel companies
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The cheapest and fastest buses from Chicago, IL to South San Francisco, CA

Showing times and prices for Apr 03

Cheapest price

$601

Average price

$601

Fastest journey

2 d 1 h 20 m

Average duration

2 d 1 h 20 m

Buses per day

1

Distance

2987 km

Cheap tickets

The best way to find a cheap bus ticket from Chicago, IL to South San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Chicago, IL to South San Francisco, CA will cost around $601 if you buy it on the day, but the cheapest tickets can be found for only $601.

Fast buses

It's difficult to get from Chicago, IL to South San Francisco, CA without transferring at least 3 times.

  • Greyhound USA
    12:01 PM49h20
    Chicago, IL
    1:21 PMSouth San Francisco, CA
    $6011One-way
    3 transfers

Chicago, IL to South San Francisco, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
12:15AM
Arrival Time
11:05AM
Duration
60h50
Departure days
Sat
Cheapest price
$355
Operator
Greyhound
Departure Time
12:25PM
Arrival Time
12:25PM
Duration
50h00
Departure days
Sat
Cheapest price
$299
Operator
Greyhound
Departure Time
11:10PM
Arrival Time
05:35PM
Duration
68h25
Departure days
Sat
Cheapest price
$323

Live departures

Chicago, IL to South San Francisco, CA bus times

The table below shows live departures for Chicago, IL to South San Francisco, CA buses for today, Thursday, April 2. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
greyhound12:01 PM Chicago, IL
49h20
1:21 PM South San Francisco, CA3 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Chicago, IL to South San Francisco, CA by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Apr 03
Sat
Apr 04
Sun
Apr 05
Mon
Apr 06
Tue
Apr 07
Wed
Apr 08
Thu
Apr 09

Journey information

Overview: Bus from Chicago, IL to South San Francisco, CA

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Take a bus from Chicago, IL to South San Francisco, CA and enjoy the approximately 1856 miles (2987 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 06:30, the last at 23:25.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
1856 miles (2987 km)
Buses per day
10
First bus
6:30 AM
Last bus
11:25 PM
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Chicago, IL to South San Francisco, CA

Find answers to the most common questions about traveling from Chicago, IL to South San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

FAQs
The earliest bus from Chicago, IL to South San Francisco, CA leaves at 6:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Chicago, IL to South San Francisco, CA leaves at 11:25 PM.
The cheapest month for a bus from Chicago, IL to South San Francisco, CA is October.
Yes, you can take a between Chicago, IL and South San Francisco, CA.
No, the bus from Chicago, IL to South San Francisco, CA has no accessibility options.
No, there are no bathrooms on board the bus from Chicago, IL to South San Francisco, CA.
No, bikes are not allowed on board the bus from Chicago, IL to South San Francisco, CA.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Chicago, IL to South San Francisco, CA.
No, luggage for the bus from Chicago, IL to South San Francisco, CA needs to be booked in addition.
No, there are no additional luggage options for the bus from Chicago, IL to South San Francisco, CA.
Unfortunately, pets are not allowed on the bus from Chicago, IL to South San Francisco, CA.
No, there are no USB plugs on board the bus from Chicago, IL to South San Francisco, CA.
No, there is no WiFi on board the bus from Chicago, IL to South San Francisco, CA.

popular bus stations

Popular bus stations from Chicago, IL to South San Francisco, CA

Chicago
South San Francisco
Chicago, Greyhound Bus Station
information
Chicago, Union Station (Amtrak)
information
Chicago, 95th Red Line Station
information

More options for your journey from Chicago, IL to South San Francisco, CA

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