Chicago, IL to South San Francisco, CA bus

Fri, Jan 02
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
National Express
1,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
National Express
1,000+ travel companies
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Journey information

Overview: Bus from Chicago, IL to South San Francisco, CA

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Take a bus from Chicago, IL to South San Francisco, CA and enjoy the approximately 1856 miles (2987 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 06:30, the last at 23:25.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
1856 miles (2987 km)
Buses per day
11
First bus
06:30
Last bus
23:25
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Chicago, IL to South San Francisco, CA

Find answers to the most common questions about traveling from Chicago, IL to South San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

FAQs
The first bus from Chicago, IL to South San Francisco, CA leaves at 4: 45AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Chicago, IL to South San Francisco, CA leaves at 11: 30PM.
A day trip to South San Francisco, CA from Chicago, IL is worth doing with a journey time of min each way. Check with Omio app   the best way to travel.
No, the bus from Chicago, IL to South San Francisco, CA has no accessibility options.
No, there are no bathrooms on board the bus from Chicago, IL to South San Francisco, CA.
No, bikes are not allowed on board the bus from Chicago, IL to South San Francisco, CA.

To find the cheapest bus tickets for your trip from Chicago, IL to South San Francisco, CA, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Chicago, IL to South San Francisco, CA.
    No, luggage for the bus from Chicago, IL to South San Francisco, CA needs to be booked in addition.
    No, there are no additional luggage options for the bus from Chicago, IL to South San Francisco, CA.
    Unfortunately, pets are not allowed on the bus from Chicago, IL to South San Francisco, CA.
    No, there are no USB plugs on board the bus from Chicago, IL to South San Francisco, CA.
    No, there is no WiFi on board the bus from Chicago, IL to South San Francisco, CA.

    popular bus stations

    Popular bus stations from Chicago, IL to South San Francisco, CA

    Chicago
    South San Francisco
    Chicago, Greyhound Bus Station
    information
    Chicago, Union Station (Amtrak)
    information

    More options for your journey from Chicago, IL to South San Francisco, CA

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