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Journey information
Overview: Bus from Chicago, IL to South San Francisco, CA
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 1856 miles (2987 km) |
Buses per day 11 |
First bus 06:30 |
Last bus 23:25 |
Key Takeaways
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
FAQs: Bus from Chicago, IL to South San Francisco, CA
Find answers to the most common questions about traveling from Chicago, IL to South San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

The first bus from Chicago, IL to South San Francisco, CA leaves at 4: 45AM. Plan your trip with the Journey Planner from Omio.
The last bus from Chicago, IL to South San Francisco, CA leaves at 11: 30PM.
A day trip to South San Francisco, CA from Chicago, IL is worth doing with a journey time of min each way. Check with Omio app the best way to travel.
No, the bus from Chicago, IL to South San Francisco, CA has no accessibility options.
No, there are no bathrooms on board the bus from Chicago, IL to South San Francisco, CA.
No, bikes are not allowed on board the bus from Chicago, IL to South San Francisco, CA.
To find the cheapest bus tickets for your trip from Chicago, IL to South San Francisco, CA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
Yes, there is food available to purchase on board the bus from Chicago, IL to South San Francisco, CA.
No, luggage for the bus from Chicago, IL to South San Francisco, CA needs to be booked in addition.
No, there are no additional luggage options for the bus from Chicago, IL to South San Francisco, CA.
Unfortunately, pets are not allowed on the bus from Chicago, IL to South San Francisco, CA.
No, there are no USB plugs on board the bus from Chicago, IL to South San Francisco, CA.
No, there is no WiFi on board the bus from Chicago, IL to South San Francisco, CA.
popular bus stations
Popular bus stations from Chicago, IL to South San Francisco, CA
Chicago
South San Francisco
Chicago, Greyhound Bus Station
information
Chicago, Union Station (Amtrak)
information
Most popular bus connections from Chicago, IL
More options for your journey from Chicago, IL to South San Francisco, CA
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