The cheapest and fastest buses from Washington, DC to South San Francisco, CA
Cheapest price
$327
Average price
$471
Fastest journey
2 d 21 h 55 m
Average duration
3 d 2 h 10 m
Buses per day
2
Distance
3922 km
The best way to find a cheap bus ticket from Washington, DC to South San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Washington, DC to South San Francisco, CA will cost around $471 if you buy it on the day, but the cheapest tickets can be found for only $327.
Of the 2 buses that leave Washington, DC for South San Francisco, CA on Fri, Jan 02, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jan 02 the direct buses cover the 3922 km distance in an average of 3 d 2 h 10 m but if you time it right, some buses will get you there in just 2 d 21 h 55 m .
On Fri, Jan 02 the slowest buses will take 3 d 6 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare bus, train, and flight for Washington, DC to South San Francisco, CA
Omio recommends booking the train as it is the most popular option from Washington, DC to South San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from €137. For those with little time consider booking a flight which can get you there in 5h 41m. The ticket price range depends on the travel mode: a bus costs an average of €137, and a train costs an average of €318.
Distance: 2437 miles (3922 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€230 Average price Cheapest | €387 Average price | €263 Average price |
73h 20m Average total duration 72h 50m Onboard + 30m Additional time* | 72h 57m Average total duration 72h 27m Onboard + 30m Additional time* | 8h 41m Average total duration Fastest 5h 41m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Washington, DC to South San Francisco, CA bus times
The table below shows live departures for Washington, DC to South San Francisco, CA buses for tomorrow, Friday, January 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:00 PM Washington, DC | 78h25 | 7:25 PM South San Francisco, CA | 0 transfersDirect | |
![]() | 9:30 PM Washington, DC | 69h55 | 7:25 PM South San Francisco, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Washington, DC to South San Francisco, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jan 02
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Jan 08
Journey information
Overview: Bus from Washington, DC to South San Francisco, CA
Buses from Washington, DC to South San Francisco, CA run on average 16 times per day, taking around 72h 50m. Cheap bus tickets for this journey start at $171 (€137) but you can travel from only $146 (€117) by flight.
The earliest bus runs at 05:35, the last at 23:55. The fastest bus covers the 2437 miles (3922 km) distance in 69h 40m.
Distance 2437 miles (3922 km) |
Average bus duration 72h 50m |
Cheapest ticket price $171 (€137) |
Buses per day 16 |
Fastest bus 69h 40m |
First bus 05:35 |
Last bus 23:55 |
FAQs: Bus from Washington, DC to South San Francisco, CA
Find answers to the most common questions about traveling from Washington, DC to South San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

To find the cheapest bus tickets for your trip from Washington, DC to South San Francisco, CA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
popular bus stations
Popular bus stations from Washington, DC to South San Francisco, CA
- 05:00-23:00
- Free Wi-Fi
- McDonald's (in the station)
- Shake Shack (in the station)
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 96, 97, D6 Metro: Red Train: Amtrak, MARC, VRE
More options for your journey from Washington, DC to South San Francisco, CA
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