The cheapest and fastest buses from Washington, DC to South San Francisco, CA
Cheapest price
$507
Average price
$531
Fastest journey
2 d 21 h 50 m
Average duration
2 d 21 h 50 m
Buses per day
2
Distance
3922 km
The best way to find a cheap bus ticket from Washington, DC to South San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Washington, DC to South San Francisco, CA will cost around $531 if you buy it on the day, but the cheapest tickets can be found for only $507.
Of the 2 buses that leave Washington, DC for South San Francisco, CA on Wed, Jul 08, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jul 08 the direct buses cover the 3922 km distance in an average of 2 d 21 h 50 m but if you time it right, some buses will get you there in just 2 d 21 h 50 m .
On Wed, Jul 08 the slowest buses will take 2 d 21 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
9:35 PM69h50Washington, DC7:25 PMSouth San Francisco, CA$5071One-way0 transfers
10:35 PM69h50Washington, DC8:25 PMSouth San Francisco, CA$5541One-way0 transfers
10:35 PM69h50Washington, DC8:25 PMSouth San Francisco, CA$5541One-way0 transfers
9:35 PM69h50Washington, DC7:25 PMSouth San Francisco, CA$5071One-way0 transfers
Travel Information
Compare bus, train, and flight for Washington, DC to South San Francisco, CA
Omio recommends booking the train as it is the most popular option from Washington, DC to South San Francisco, CA among Omio's users. If you are prioritising price take the flight with prices starting from $258. For those with little time consider booking a flight which can get you there in 5h 41m. The ticket price range depends on the travel mode: a flight costs an average of $258, and a train costs an average of $575.
Distance: 2437 miles (3922 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$521 Average price | $1103 Average price | $314 Average price Cheapest |
66h 25m Average total duration 65h 55m Onboard + 30m Additional time* | 76h 3m Average total duration 75h 33m Onboard + 30m Additional time* | 8h 41m Average total duration Fastest 5h 41m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Washington, DC to South San Francisco, CA:
A flight is $207 (€170) less than a bus for this route with tickets for a bus from Washington, DC to South San Francisco, CA costing on average $521 (€428).
A flight is $789 (€649) less than a train for this route with tickets for a train from Washington, DC to South San Francisco, CA costing on average $1103 (€907).
Other travel options to South San Francisco, CA take longer:
Bus takes on average 65h 55m.
Train takes on average 75h 33m.
Washington, DC to South San Francisco, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 10:45AM | Arrival Time 08:13AM | Duration 69h28 | Departure days Tue | Cheapest price $840 |
Operator Greyhound USA | Departure Time 05:35PM | Arrival Time 01:37PM | Duration 68h02 | Departure days Tue, Sat | Cheapest price $783 |
Operator Greyhound | Departure Time 09:35PM | Arrival Time 07:25PM | Duration 69h50 | Departure days Mon, Wed, Thu | Cheapest price $507 |
Operator Greyhound | Departure Time 10:30PM | Arrival Time 12:35AM | Duration 98h05 | Departure days Thu | Cheapest price $449 |
Operator Greyhound | Departure Time 10:35PM | Arrival Time 08:25PM | Duration 69h50 | Departure days Wed, Thu, Sun | Cheapest price $554 |
Live departures
Washington, DC to South San Francisco, CA bus times
The table below shows live departures for Washington, DC to South San Francisco, CA buses for tomorrow, Wednesday, July 8. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:35 PM Washington, DC | 69h50 | 7:25 PM South San Francisco, CA | 0 transfersDirect | |
![]() | 10:35 PM Washington, DC | 69h50 | 8:25 PM South San Francisco, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Washington, DC to South San Francisco, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jul 08
Jul 09
Jul 10
Jul 11
Jul 12
Jul 13
Jul 14
Why should you book Washington, DC to South San Francisco, CA buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Washington, DC to South San Francisco, CA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Washington, DC to South San Francisco, CA.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Washington, DC to South San Francisco, CA.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Washington, DC to South San Francisco, CA.
Journey information
Overview: Bus from Washington, DC to South San Francisco, CA
Buses from Washington, DC to South San Francisco, CA run on average 11 times per day, taking around 65h 55m. Cheap bus tickets for this journey start at $329 (€270) but you can travel from only $258 (€212) by flight.
The earliest bus runs at 05:00, the last at 23:55. The fastest bus covers the 2437 miles (3922 km) distance in 69h 50m.
Distance 2437 miles (3922 km) |
Average bus duration 65h 55m |
Cheapest ticket price $329 (€270) |
Buses per day 11 |
Fastest bus 69h 50m |
First bus 5:00 AM |
Last bus 11:55 PM |
Cheapest Month Jul |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Apr - Jun |
Best time to book 14 days |
Bus providers: Greyhound, FlixBus from Washington, DC to South San Francisco, CAYou can travel by bus between Washington, DC to South San Francisco, CA with Greyhound, FlixBus for as low as $258 (€212). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Washington, DC to South San Francisco, CA
Find answers to the most common questions about traveling from Washington, DC to South San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Washington, DC to South San Francisco, CA
Most Washington, DC to South San Francisco, CA buses use the Washington, Columbus Circle, Union Station to San Francisco, Transit Center Bay 29 station pair. Use this guide to compare Washington, DC and South San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Washington, DC station do buses to South San Francisco, CA leave from?
Getting to Washington, Columbus Circle, Union Station from Washington city centre
Washington, Columbus Circle, Union Station is 2 km from Washington city centre. Public transport options include:
Washington, Columbus Circle, Union Station bus station facilities and services
Washington, Columbus Circle, Union Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: McDonald's (in the station), Shake Shack (in the station)
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and food court.
Tickets and information
Ticket office support is available at Washington, Columbus Circle, Union Station.
Parking, taxis and toilets
Available at Washington, Columbus Circle, Union Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Washington, Columbus Circle, Union Station: Elevators, ramps.
Getting to Washington, DuPont Circle (Connecticut Ave. NW / 20th St. NW) from Washington city centre
More options for your journey from Washington, DC to South San Francisco, CA
Here are some other resources that might have the information you need


