4.9
4.6The cheapest and fastest buses from Philadelphia, PA to South San Francisco, CA
Cheapest price
$863
Average price
$863
Fastest journey
2 d 20 h 12 m
Average duration
2 d 20 h 12 m
Buses per day
1
Distance
4054 km
The best way to find a cheap bus ticket from Philadelphia, PA to South San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Philadelphia, PA to South San Francisco, CA will cost around $863 if you buy it on the day, but the cheapest tickets can be found for only $863.
It's difficult to get from Philadelphia, PA to South San Francisco, CA without transferring at least 3 times.
12:05 PM68h12Philadelphia, PA8:17 AMSouth San Francisco, CA$8631One-way3 transfers
- 12:05 PM68h12Philadelphia, PA8:17 AMSouth San Francisco, CA$8631One-way3 transfers
Travel Information
Compare bus, train, and flight for Philadelphia, PA to South San Francisco, CA
Omio recommends booking the train as it is the most popular option from Philadelphia, PA to South San Francisco, CA among Omio's users. If you are prioritising price take the flight with prices starting from $212. For those with little time consider booking a flight which can get you there in 9h 28m. The ticket price range depends on the travel mode: a flight costs an average of $212, and a train costs an average of $687.
Distance: 2519 miles (4054 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$557 Average price | $1614 Average price | $310 Average price Cheapest | $579 Average price (fuel + tolls) |
67h 5m Average total duration 66h 35m Onboard + 30m Additional time* | 70h 37m Average total duration 70h 7m Onboard + 30m Additional time* | 12h 28m Average total duration Fastest 9h 28m Onboard + 3h 0m Additional time* | 42h 18m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Philadelphia, PA to South San Francisco, CA:
A flight is $247 (€203) less than a bus for this route with tickets for a bus from Philadelphia, PA to South San Francisco, CA costing on average $557 (€458).
A flight is $1304 (€1072) less than a train for this route with tickets for a train from Philadelphia, PA to South San Francisco, CA costing on average $1614 (€1326).
Other travel options to South San Francisco, CA take longer:
Bus takes on average 66h 35m.
Train takes on average 70h 7m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Philadelphia, PA to South San Francisco, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 07:10AM | Arrival Time 12:35PM | Duration 80h25 | Departure days Tue | Cheapest price $749 |
Operator Greyhound USA | Departure Time 12:05PM | Arrival Time 08:17AM | Duration 68h12 | Departure days Tue, Wed | Cheapest price $844 |
Operator Greyhound | Departure Time 02:05PM | Arrival Time 07:10AM | Duration 92h05 | Departure days Tue | Cheapest price $747 |
Operator Greyhound | Departure Time 05:35PM | Arrival Time 12:35PM | Duration 70h00 | Departure days Tue | Cheapest price $719 |
Operator Greyhound | Departure Time 07:00PM | Arrival Time 08:25PM | Duration 73h25 | Departure days Fri | Cheapest price $638 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 07:25PM | Duration 69h55 | Departure days Mon, Sat | Cheapest price $324 |
Operator Greyhound | Departure Time 10:30PM | Arrival Time 01:05AM | Duration 74h35 | Departure days Mon, Thu | Cheapest price $542 |
Operator Greyhound | Departure Time 11:55PM | Arrival Time 07:10AM | Duration 82h15 | Departure days Tue | Cheapest price $773 |
Live departures
Philadelphia, PA to South San Francisco, CA bus times
The table below shows live departures for Philadelphia, PA to South San Francisco, CA buses for today, Tuesday, July 7. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 FlixBus+ · · | 11:55 PM Philadelphia Bus Station | 82h15 | 7:10 AM San Francisco, Transit Center Bay 29 | 4 transfers | |
| Wednesday, July 8 | |||||
| 12:05 PM Philadelphia, PA | 68h12 | 8:17 AM South San Francisco, CA | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Philadelphia, PA to South San Francisco, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jul 08
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Jul 14
Why should you book Philadelphia, PA to South San Francisco, CA buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Philadelphia, PA to South San Francisco, CA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Philadelphia, PA to South San Francisco, CA.
Journey information
Overview: Bus from Philadelphia, PA to South San Francisco, CA
USAUSA
Buses from Philadelphia, PA to South San Francisco, CA run on average 15 times per day, taking around 66h 35m. Cheap bus tickets for this journey start at $324 (€267) but you can travel from only $212 (€174) by flight.
The earliest bus runs at 07:00, the last at 23:25. The fastest bus covers the 2519 miles (4054 km) distance in 69h 55m.
Distance 2519 miles (4054 km) |
Average bus duration 66h 35m |
Cheapest ticket price $324 (€267) |
Buses per day 15 |
Fastest bus 69h 55m |
First bus 7:00 AM |
Last bus 11:25 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Jul - Sep |
Bus providers: Greyhound from Philadelphia, PA to South San Francisco, CAYou can travel by bus between Philadelphia, PA to South San Francisco, CA with Greyhound for as low as $212 (€174). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Philadelphia, PA to South San Francisco, CA
Find answers to the most common questions about traveling from Philadelphia, PA to South San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Philadelphia, PA to South San Francisco, CA
Most Philadelphia, PA to South San Francisco, CA buses use the Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park) to San Francisco, Transit Center Bay 29 station pair. Use this guide to compare Philadelphia, PA and South San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to Philadelphia, Greyhound Bus Station from Philadelphia city centre
Most popular bus connections from Philadelphia, PA
More options for your journey from Philadelphia, PA to South San Francisco, CA
Here are some other resources that might have the information you need
Most popular buses to and from South San Francisco, CA and Philadelphia, PA
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