Philadelphia, PA to South San Francisco, CA bus with Greyhound

Sat, Feb 14
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The cheapest and fastest buses from Philadelphia, PA to South San Francisco, CA

Showing times and prices for Feb 17

Cheapest price

$164

Average price

$164

Fastest journey

3 d 23 h 55 m

Average duration

3 d 23 h 55 m

Buses per day

1

Distance

4054 km

Cheap tickets

The best way to find a cheap bus ticket from Philadelphia, PA to South San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Philadelphia, PA to South San Francisco, CA will cost around $164 if you buy it on the day, but the cheapest tickets can be found for only $164.

Fast buses

Of the 1 buses that leave Philadelphia, PA for South San Francisco, CA on Tue, Feb 17, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Tue, Feb 17 the direct buses cover the 4054 km distance in an average of 3 d 23 h 55 m but if you time it right, some buses will get you there in just 3 d 23 h 55 m .

On Tue, Feb 17 the slowest buses will take 3 d 23 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

Greyhound
02:20PM95h55
Philadelphia, PA
02:15PMSouth San Francisco, CA
$1641One-way
0 transfers

Travel Information

Compare bus, train, and flight for Philadelphia, PA to South San Francisco, CA

Omio recommends booking the bus as it is the most popular option from Philadelphia, PA to South San Francisco, CA among Omio's users. If you are prioritising price take the flight with prices starting from €193. For those with little time consider booking a flight which can get you there in 10h 26m. The ticket price range depends on the travel mode: a flight costs an average of €193, and a train costs an average of €367.

Distance: 2519 miles (4054 km)

Compare bus with

Most popular
Bus
Train
Flight

€469

Average price

€550

Average price

€222

Average price

Cheapest

67h 5m

Average total duration

66h 35m

Onboard

+

30m

Additional time*

79h 58m

Average total duration

79h 28m

Onboard

+

30m

Additional time*

13h 26m

Average total duration

Fastest

10h 26m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Compare prices and tickets Philadelphia, PA to South San Francisco, CA by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
Feb 17
Wed
Feb 18
Thu
Feb 19
Fri
Feb 20
Sat
Feb 21
Sun
Feb 22
Mon
Feb 23

Why should you book Philadelphia, PA to South San Francisco, CA buses with Omio?

Greyhound operates all buses services from Philadelphia, PA to South San Francisco, CA.
Omio is an official ticket reseller for all your travel options from Philadelphia, PA to South San Francisco, CA.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of to find the best option for your trip from Philadelphia, PA to South San Francisco, CA.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Philadelphia, PA to South San Francisco, CA.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Philadelphia, PA to South San Francisco, CA.

Journey information

Overview: Bus from Philadelphia, PA to South San Francisco, CA

USAUSA
USAUSA
Icon of bus

Buses from Philadelphia, PA to South San Francisco, CA run on average 18 times per day, taking around 66h 35m. Cheap bus tickets for this journey start at $252 (€200) but you can travel from only $244 (€193) by flight.

The earliest bus runs at 12:10, the last at 22:30. The fastest bus covers the 2519 miles (4054 km) distance in 69h 55m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $244 (€193)
Distance
2519 miles (4054 km)
Average bus duration
66h 35m
Cheapest ticket price
$252 (€200)
Buses per day
18
Fastest bus
69h 55m
First bus
12:10
Last bus
22:30
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $244 (€193)

Bus providers: Greyhound from Philadelphia, PA to South San Francisco, CAYou can travel by bus between Philadelphia, PA to South San Francisco, CA with Greyhound for as low as $244 (€193). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
87h 45m
Cheapest Price
$164 (€130)
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from Philadelphia, PA to South San Francisco, CA

Find answers to the most common questions about traveling from Philadelphia, PA to South San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Philadelphia, PA to South San Francisco, CA can start from as little as $252 (€200) when you book in advance. The average bus ticket price for Philadelphia, PA to South San Francisco, CA is $593 (€469) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Philadelphia, PA to South San Francisco, CA is 69h 55m to travel the 2519 miles (4054 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Philadelphia, PA to South San Francisco, CA leaves at 12:10 PM. Plan your trip with the Journey Planner from Omio.
The latest bus from Philadelphia, PA to South San Francisco, CA leaves at 10:30 PM.
There are 18 buses a day from Philadelphia, PA to South San Francisco, CA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Philadelphia, PA to South San Francisco, CA, you can count on Greyhound for the best way to get you to South San Francisco, CA. You can also check all possible bus companies who offer a service between Philadelphia, PA and South San Francisco, CA and compare the amenities they offer before buying a bus ticket.
A trip to South San Francisco, CA from Philadelphia, PA is worth doing but not as a day trip with a journey time of 69h 55m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Philadelphia, PA to South San Francisco, CA is July.
It's helpful to compare your options as there are 3 ways to travel between Philadelphia, PA and South San Francisco, CA including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Philadelphia, PA to South San Francisco, CA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Philadelphia, PA to South San Francisco, CA for bus company Greyhound.
Whether you can cancel your bus ticket from Philadelphia, PA to South San Francisco, CA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Philadelphia, PA to South San Francisco, CA.
Yes, the following luggage options are included when booking a bus ticket from Philadelphia, PA to South San Francisco, CA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Philadelphia, PA to South San Francisco, CA:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Philadelphia, PA to South San Francisco, CA.
You can reserve your seat on the bus from Philadelphia, PA to South San Francisco, CA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Philadelphia, PA to South San Francisco, CA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Philadelphia, PA to South San Francisco, CA with the following bus company: Greyhound.

popular bus stations

Popular bus stations from Philadelphia, PA to South San Francisco, CA

Philadelphia
South San Francisco
Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park)
information
Philadelphia, Schuylkill Ave (Cira Centre South)
information
Philadelphia
information

More options for your journey from Philadelphia, PA to South San Francisco, CA

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