Travel Information
Compare bus and flight for Salem, OR to South San Francisco, CA
Omio recommends booking the bus as it is the most popular option from Salem, OR to South San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $174. For those with little time consider booking a flight which can get you there in 5h 11m. The ticket price range depends on the travel mode: a bus costs an average of $174, and a flight costs an average of $257.
Distance: 504 miles (812 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
$174 Average price Cheapest | $257 Average price | $122 Average price (fuel + tolls) |
15h 50m Average total duration 15h 20m Onboard + 30m Additional time* | 8h 11m Average total duration Fastest 5h 11m Onboard + 3h 0m Additional time* | 9h 2m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Salem, OR to South San Francisco, CA:
A bus is $82 (€67) less than a flight for this route with tickets for a flight from Salem, OR to South San Francisco, CA costing on average $257 (€207).
Other travel options to South San Francisco, CA take longer:
Bus takes on average 15h 20m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Salem, OR to South San Francisco, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:05AM | Arrival Time 07:25PM | Duration 15h20 | Departure days Sat | Cheapest price $174 |
Operator Flixbus USA | Departure Time 09:05PM | Arrival Time 01:37PM | Duration 16h32 | Departure days Tue, Wed, Thu, Sat, Sun | Cheapest price $120 |
Live departures
Salem, OR to South San Francisco, CA bus times
The table below shows live departures for Salem, OR to South San Francisco, CA buses for today, Sunday, May 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:05 PM Salem, OR | 16h32 | 1:37 PM South San Francisco, CA | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Salem, OR to South San Francisco, CA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 18
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May 24
Why should you book Salem, OR to South San Francisco, CA buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Salem, OR to South San Francisco, CA.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Salem, OR to South San Francisco, CA.
Journey information
Overview: Bus from Salem, OR to South San Francisco, CA
Buses from Salem, OR to South San Francisco, CA run on average 1 times per day, taking around 15h 20m. Cheap bus tickets for this journey start at $174 (€141) if you book in advance.
The earliest bus runs at 04:05, the last at 04:05. The fastest bus covers the 504 miles (812 km) distance in 15h 20m.
Distance 504 miles (812 km) |
Average bus duration 15h 20m |
Cheapest ticket price $174 (€141) |
Buses per day 1 |
Fastest bus 15h 20m |
First bus 4:05 AM |
Last bus 4:05 AM |
Cheapest Month Apr |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Apr - Jun |
Bus providers: FlixBus from Salem, OR to South San Francisco, CAYou can travel by bus between Salem, OR to South San Francisco, CA with FlixBus for as low as $174 (€141). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Salem, OR to South San Francisco, CA
Find answers to the most common questions about traveling from Salem, OR to South San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Salem, OR to South San Francisco, CA
Most popular bus connections from Salem, OR
More options for your journey from Salem, OR to South San Francisco, CA
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