Los Angeles, CA to South San Francisco, CA bus with Greyhound

Mon, May 18
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The cheapest and fastest buses from Los Angeles, CA to South San Francisco, CA

Showing times and prices for May 18

Cheapest price

$60

Average price

$60

Fastest journey

10 h 27 m

Average duration

10 h 27 m

Buses per day

1

Distance

549 km

Cheap tickets

The best way to find a cheap bus ticket from Los Angeles, CA to South San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Los Angeles, CA to South San Francisco, CA will cost around $60 if you buy it on the day, but the cheapest tickets can be found for only $60.

Fast buses

Of the 1 buses that leave Los Angeles, CA for South San Francisco, CA on Mon, May 18, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Mon, May 18 the direct buses cover the 549 km distance in an average of 10 h 27 m but if you time it right, some buses will get you there in just 10 h 27 m .

On Mon, May 18 the slowest buses will take 10 h 27 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Amtrak
    6:13 PM10h27
    Los Angeles, CA
    4:40 AMSouth San Francisco, CA
    $601One-way
    0 transfers

Travel Information

Compare train, bus, and flight for Los Angeles, CA to South San Francisco, CA

Omio recommends booking the train as it is the most popular option from Los Angeles, CA to South San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $48. For those with little time consider booking a flight which can get you there in 1h 26m. The ticket price range depends on the travel mode: a bus costs an average of $48, and a flight costs an average of $63.

Distance: 341 miles (549 km)

Compare bus with

Bus
Most popular
Train
Flight

$57

Average price

Cheapest

$78

Average price

$160

Average price

10h 44m

Average total duration

10h 14m

Onboard

+

30m

Additional time*

11h 58m

Average total duration

11h 28m

Onboard

+

30m

Additional time*

4h 26m

Average total duration

Fastest

1h 26m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Los Angeles, CA to South San Francisco, CA is a bus with an average price of $57 (€46).

This is compared to other travel options from Los Angeles, CA to South San Francisco, CA:

A bus is $21 (€17) less than a train for this route with tickets for a train from Los Angeles, CA to South San Francisco, CA costing on average $78 (€63).

A bus is $103 (€83) less than a flight for this route with tickets for a flight from Los Angeles, CA to South San Francisco, CA costing on average $160 (€129).

The fastest way to travel from Los Angeles, CA to South San Francisco, CA is by flight with an average journey time of 1h 26m.

Other travel options to South San Francisco, CA take longer:

Bus takes on average 10h 14m.

Train takes on average 11h 28m.

It's helpful to compare your options as there are 3 ways to travel between Los Angeles, CA and South San Francisco, CA including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Los Angeles, CA to South San Francisco, CA among Omio's users.

Los Angeles, CA to South San Francisco, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Amtrak
Departure Time
04:50AM
Arrival Time
06:10PM
Duration
13h20
Departure days
Thu
Cheapest price
$125
Operator
FlixBus
Departure Time
06:15AM
Arrival Time
01:40PM
Duration
7h25
Departure days
Wed
Cheapest price
$58
Operator
Amtrak
Departure Time
07:13AM
Arrival Time
07:20PM
Duration
12h07
Departure days
Thu, Sat
Cheapest price
$79
Operator
Greyhound
Departure Time
07:45AM
Arrival Time
08:25PM
Duration
12h40
Departure days
Sat
Cheapest price
$48
Operator
Flixbus USA
Departure Time
09:30AM
Arrival Time
07:16PM
Duration
9h46
Departure days
Sun
Cheapest price
$78
Operator
Amtrak
Departure Time
11:13AM
Arrival Time
09:40PM
Duration
10h27
Departure days
Thu, Sat
Cheapest price
$58
Operator
FlixBus
Departure Time
11:40AM
Arrival Time
08:20PM
Duration
8h40
Departure days
Thu, Sat
Cheapest price
$75
Operator
Amtrak
Departure Time
06:13PM
Arrival Time
04:40AM
Duration
10h27
Departure days
Mon, Tue, Wed, Fri
Cheapest price
$58
Operator
Amtrak
Departure Time
07:13PM
Arrival Time
05:40AM
Duration
10h27
Departure days
Thu, Fri, Sat
Cheapest price
$58
Operator
Greyhound
Departure Time
07:40PM
Arrival Time
05:05AM
Duration
9h25
Departure days
Wed, Fri
Cheapest price
$48
Operator
FlixBus
Departure Time
10:45PM
Arrival Time
06:40AM
Duration
7h55
Departure days
Thu, Sat
Cheapest price
$69
Operator
Greyhound USA
Departure Time
11:05PM
Arrival Time
08:13AM
Duration
9h08
Departure days
Thu, Sat, Sun
Cheapest price
$95
Operator
FlixBus
Departure Time
11:15PM
Arrival Time
06:40AM
Duration
7h25
Departure days
Thu, Sat
Cheapest price
$69
Operator
Greyhound
Departure Time
11:50PM
Arrival Time
12:25PM
Duration
12h35
Departure days
Thu, Sat
Cheapest price
$69

Live departures

Los Angeles, CA to South San Francisco, CA bus times

The table below shows live departures for Los Angeles, CA to South San Francisco, CA buses for today, Sunday, May 17. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Flixbus USA9:30 AM Los Angeles, CA
9h46
7:16 PM South San Francisco, CA3 transfers
Flixbus USA9:30 AM Los Angeles, CA
9h46
7:16 PM South San Francisco, CA2 transfers
Greyhound USA11:05 PM Los Angeles, CA
9h08
8:13 AM South San Francisco, CA1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Los Angeles, CA to South San Francisco, CA by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
May 18
Tue
May 19
Wed
May 20
Thu
May 21
Fri
May 22
Sat
May 23
Sun
May 24

Why should you book Los Angeles, CA to South San Francisco, CA buses with Omio?

Greyhound as well as FlixBus offer buses services from Los Angeles, CA to South San Francisco, CA.
Omio is an official ticket reseller for all your travel options from Los Angeles, CA to South San Francisco, CA.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Los Angeles, CA to South San Francisco, CA.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Los Angeles, CA to South San Francisco, CA.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Los Angeles, CA to South San Francisco, CA.
  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Los Angeles, CA to South San Francisco, CA.

Journey information

Overview: Bus from Los Angeles, CA to South San Francisco, CA

USAUSA
USAUSA
Icon of bus

Buses from Los Angeles, CA to South San Francisco, CA run on average 20 times per day, taking around 10h 14m. Cheap bus tickets for this journey start at $48 (€39) if you book in advance.

There are 4 buses per day. The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 341 miles (549 km) distance in 7h 25m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
341 miles (549 km)
Average bus duration
10h 14m
Cheapest ticket price
$48 (€39)
Buses per day
20
Direct buses
4
Fastest bus
7h 25m
First bus
12:15 AM
Last bus
11:55 PM
Cheapest Month
Nov
Cheapest Day
Tue
High Season
Jan - Mar
Low Season
Jul - Sep
Best time to book
14 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, FlixBus from Los Angeles, CA to South San Francisco, CAYou can travel by bus between Los Angeles, CA to South San Francisco, CA with Greyhound, FlixBus for as low as $48 (€39). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
7h 25m
Cheapest Price
$58 (€47)
FlixBus frequency
4 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
9h 25m
Cheapest Price
$48 (€39)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Learn more about Greyhound

FAQs: Bus from Los Angeles, CA to South San Francisco, CA

Find answers to the most common questions about traveling from Los Angeles, CA to South San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Los Angeles, CA to South San Francisco, CA can start from as little as $48 (€39) when you book in advance. The average bus ticket price for Los Angeles, CA to South San Francisco, CA is $57 (€46) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Los Angeles, CA to South San Francisco, CA is 7h 25m to travel the 341 miles (549 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Los Angeles, CA to South San Francisco, CA leaves at 12:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Los Angeles, CA to South San Francisco, CA leaves at 11:55 PM.
Yes, there are 4 direct buses a day from Los Angeles, CA to South San Francisco, CA with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Los Angeles, CA to South San Francisco, CA, you can count on Greyhound, FlixBus for the best way to get you to South San Francisco, CA. You can also check all possible bus companies who offer a service between Los Angeles, CA and South San Francisco, CA and compare the amenities they offer before buying a bus ticket.
A trip to South San Francisco, CA from Los Angeles, CA is worth doing but not as a day trip with a journey time of 7h 25m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Los Angeles, CA to South San Francisco, CA is November.
It's helpful to compare your options as there are 3 ways to travel between Los Angeles, CA and South San Francisco, CA including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Los Angeles, CA to South San Francisco, CA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Los Angeles, CA to South San Francisco, CA for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from Los Angeles, CA to South San Francisco, CA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Los Angeles, CA to South San Francisco, CA.
Yes, the following luggage options are included when booking a bus ticket from Los Angeles, CA to South San Francisco, CA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Los Angeles, CA to South San Francisco, CA:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Los Angeles, CA to South San Francisco, CA. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Los Angeles, CA to South San Francisco, CA with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Los Angeles, CA to South San Francisco, CA with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Los Angeles, CA to South San Francisco, CA with the following bus company: Greyhound, FlixBus.
Since neither Los Angeles, CA nor South San Francisco, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Los Angeles, CA to South San Francisco, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In South San Francisco, CA, travelers should be cautious of petty crimes such as pickpocketing and vehicle break-ins, especially in crowded or tourist-heavy areas. Common scams include overcharging by unlicensed taxi drivers or ride-share services, so it's advisable to use reputable transportation options. Staying aware of surroundings and securing personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Los Angeles, CA to South San Francisco, CA

Los Angeles
South San Francisco
Los Angeles, Patsaouras Transit Plaza (Union Station)
information
Los Angeles, Gayley / Strathmore
information
Los Angeles, Cesar E Chavez / Vignes
information

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