The cheapest and fastest buses from Los Angeles, CA to South San Francisco, CA
Cheapest price on Oct 08
$56
Average ticket price on Oct 08
$57
Fastest journey on Oct 08
10 h 27 m
Average journey duration on Oct 08
10 h 27 m
Buses on Oct 08
2
Distance
549 km
The best way to find a cheap bus ticket from Los Angeles, CA to South San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Los Angeles, CA to South San Francisco, CA will cost around $57 if you buy it on the day, but the cheapest tickets can be found for only $56.
On Thu, Oct 08, we found 2 buses from Los Angeles, CA to South San Francisco, CA, including 2 direct services.
On Thu, Oct 08 the direct buses cover the 549 km distance in an average of 10 h 27 m but if you time it right, some buses will get you there in just 10 h 27 m .
On Thu, Oct 08 the slowest buses will take 10 h 27 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
7:13 PM10h27Los Angeles, CA5:40 AMSouth San Francisco, CA$561One-way0 transfers
6:13 PM10h27Los Angeles, CA4:40 AMSouth San Francisco, CA$571One-way0 transfers
7:13 PM10h27Los Angeles, CA5:40 AMSouth San Francisco, CA$561One-way0 transfers
6:13 PM10h27Los Angeles, CA4:40 AMSouth San Francisco, CA$571One-way0 transfers
Journey information
Overview: Bus from Los Angeles, CA to South San Francisco, CA
Buses from Los Angeles, CA to South San Francisco, CA run on average 3 times per day, taking around 9h 13m. Cheap bus tickets for this journey start at $48 (€40) if you book in advance.
There are 2 buses per day. The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 341 miles (549 km) distance in 7h 0m.
Distance 341 miles (549 km) |
Average bus duration 9h 13m |
Cheapest ticket price $48 (€40) |
Buses per day 3 |
Direct buses 2 |
Fastest bus 7h 0m |
First bus 12:15 AM |
Last bus 11:55 PM |
Cheapest Month Nov |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Oct - Dec |
Best time to book 63 days |
Los Angeles, CA to South San Francisco, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:15AM | Arrival Time 01:40PM | Duration 7h25 | Departure days Wed | Cheapest price $56 |
Operator Greyhound | Departure Time 07:45AM | Arrival Time 08:25PM | Duration 12h40 | Departure days Sat | Cheapest price $47 |
Operator Flixbus USA | Departure Time 09:30AM | Arrival Time 07:16PM | Duration 9h46 | Departure days Sun | Cheapest price $76 |
Operator Amtrak | Departure Time 05:26PM | Arrival Time 03:30AM | Duration 10h04 | Departure days Sat | Cheapest price $56 |
Operator Amtrak | Departure Time 06:13PM | Arrival Time 04:40AM | Duration 10h27 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $56 |
Operator Amtrak | Departure Time 07:13PM | Arrival Time 05:40AM | Duration 10h27 | Departure days Thu, Fri | Cheapest price $56 |
Operator Greyhound | Departure Time 07:40PM | Arrival Time 05:05AM | Duration 9h25 | Departure days Wed, Fri | Cheapest price $47 |
Operator Greyhound USA | Departure Time 11:05PM | Arrival Time 08:13AM | Duration 9h08 | Departure days Sun | Cheapest price $109 |
Live departures
Los Angeles, CA to South San Francisco, CA bus times
The table below shows live departures for Los Angeles, CA to South San Francisco, CA buses for today, Wednesday, October 7. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:13 PM Los Angeles, CA | 10h27 | 4:40 AM South San Francisco, CA | 0 transfersDirect | |
![]() | 7:40 PM Los Angeles, CA | 9h25 | 5:05 AM South San Francisco, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Los Angeles, CA to South San Francisco, CA buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Los Angeles, CA to South San Francisco, CA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Los Angeles, CA to South San Francisco, CA.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Los Angeles, CA to South San Francisco, CA.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Los Angeles, CA to South San Francisco, CA.
Bus providers: Greyhound, FlixBus from Los Angeles, CA to South San Francisco, CAYou can travel by bus between Los Angeles, CA to South San Francisco, CA with Greyhound, FlixBus for as low as $48 (€40). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Los Angeles, CA to South San Francisco, CA
Find answers to the most common questions about traveling from Los Angeles, CA to South San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Los Angeles, CA to South San Francisco, CA
Most Los Angeles, CA to South San Francisco, CA buses use the Los Angeles, Patsaouras Transit Plaza (Union Station) to San Francisco, Townsend Street / 5th Street station pair. Use this guide to compare Los Angeles, CA and South San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Los Angeles, CA station do buses to South San Francisco, CA leave from?
Getting to Los Angeles, Patsaouras Transit Plaza (Union Station) from Los Angeles city centre
Los Angeles, Patsaouras Transit Plaza (Union Station) is 1 km from Los Angeles city centre. Public transport options include:
Los Angeles, Patsaouras Transit Plaza (Union Station) bus station facilities and services
Los Angeles, Patsaouras Transit Plaza (Union Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Food court and various dining options available.
Wi-Fi and ATMs
Wi-Fi available in main waiting areas. ATMs are aTMs available near main concourse.
Tickets and information
Ticket office support is available at Los Angeles, Patsaouras Transit Plaza (Union Station).
Parking, taxis and toilets
Available at Los Angeles, Patsaouras Transit Plaza (Union Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Los Angeles, Patsaouras Transit Plaza (Union Station): Station fully accessible with elevators and ramps.
Getting to Los Angeles, Gayley / Strathmore from Los Angeles city centre
Los Angeles, Gayley / Strathmore is 19 km from Los Angeles city centre. Public transport options include:
Los Angeles, Gayley / Strathmore bus station facilities and services
Los Angeles, Gayley / Strathmore has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Los Angeles, Gayley / Strathmore. ATMs are available at Los Angeles, Gayley / Strathmore.
Tickets and information
Ticket office support is available at Los Angeles, Gayley / Strathmore.
Parking, taxis and toilets
Available at Los Angeles, Gayley / Strathmore: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Los Angeles, Gayley / Strathmore: Basic accessibility features available for buses.
Most popular bus connections from Los Angeles, CA
More options for your journey from Los Angeles, CA to South San Francisco, CA
Here are some other resources that might have the information you need

