Travel Information
Compare bus, train, and flight for Los Angeles, CA to South San Francisco, CA
Omio recommends booking the train as it is the most popular option from Los Angeles, CA to South San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from €39. For those with little time consider booking a flight which can get you there in 1h 26m. The ticket price range depends on the travel mode: a bus costs an average of €39, and a flight costs an average of €51.
Distance: 341 miles (549 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€44 Average price Cheapest | €61 Average price | €86 Average price |
11h 44m Average total duration 11h 14m Onboard + 30m Additional time* | 11h 58m Average total duration 11h 28m Onboard + 30m Additional time* | 4h 26m Average total duration Fastest 1h 26m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Los Angeles, CA to South San Francisco, CA bus times
The table below shows live departures for Los Angeles, CA to South San Francisco, CA buses for today, Monday, February 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:45 AM Los Angeles, CA | 12h40 | 8:25 PM South San Francisco, CA | 0 transfersDirect | |
![]() | 5:13 PM Los Angeles, CA | 10h17 | 3:30 AM South San Francisco, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Los Angeles, CA to South San Francisco, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Los Angeles, CA to South San Francisco, CA
Buses from Los Angeles, CA to South San Francisco, CA run on average 32 times per day, taking around 11h 14m. Cheap bus tickets for this journey start at $49 (€39) if you book in advance.
There are 6 buses per day. The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 341 miles (549 km) distance in 10h 4m.
Distance 341 miles (549 km) |
Average bus duration 11h 14m |
Cheapest ticket price $49 (€39) |
Buses per day 32 |
Direct buses 6 |
Fastest bus 10h 4m |
First bus 00:15 |
Last bus 23:55 |
FAQs: Bus from Los Angeles, CA to South San Francisco, CA
Find answers to the most common questions about traveling from Los Angeles, CA to South San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Los Angeles, CA to South San Francisco, CA
Most popular bus connections from Los Angeles, CA
More options for your journey from Los Angeles, CA to South San Francisco, CA
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