The cheapest and fastest buses from Los Angeles, CA to South San Francisco, CA
Cheapest price
CHF48
Average price
CHF48
Fastest journey
10 h 27 m
Average duration
10 h 27 m
Buses per day
1
Distance
549 km
The best way to find a cheap bus ticket from Los Angeles, CA to South San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Los Angeles, CA to South San Francisco, CA will cost around CHF48 if you buy it on the day, but the cheapest tickets can be found for only CHF48.
Of the 1 buses that leave Los Angeles, CA for South San Francisco, CA on Mon, Aug 24, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Aug 24 the direct buses cover the 549 km distance in an average of 10 h 27 m but if you time it right, some buses will get you there in just 10 h 27 m .
On Mon, Aug 24 the slowest buses will take 10 h 27 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
6:13 PM10h27Los Angeles, CA4:40 AMSouth San Francisco, CACHF481One-way0 transfers
6:13 PM10h27Los Angeles, CA4:40 AMSouth San Francisco, CACHF481One-way0 transfers
Travel Information
Compare train, bus, and flight for Los Angeles, CA to South San Francisco, CA
Omio recommends booking the train as it is the most popular option from Los Angeles, CA to South San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from CHF34. For those with little time consider booking a flight which can get you there in 1h 26m. The ticket price range depends on the travel mode: a bus costs an average of CHF34, and a flight costs an average of CHF50.
Distance: 341 miles (549 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
CHF43 Average price Cheapest | CHF65 Average price | CHF87 Average price |
10h 6m Average total duration 9h 36m Onboard + 30m Additional time* | 11h 58m Average total duration 11h 28m Onboard + 30m Additional time* | 4h 26m Average total duration Fastest 1h 26m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Los Angeles, CA to South San Francisco, CA:
A bus is CHF22 less than a train for this route with tickets for a train from Los Angeles, CA to South San Francisco, CA costing on average CHF65.
A bus is CHF44 less than a flight for this route with tickets for a flight from Los Angeles, CA to South San Francisco, CA costing on average CHF87.
Other travel options to South San Francisco, CA take longer:
Bus takes on average 9h 36m.
Train takes on average 11h 28m.
Los Angeles, CA to South San Francisco, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:15AM | Arrival Time 01:40PM | Duration 7h25 | Departure days Wed | Cheapest price CHF47 |
Operator Greyhound | Departure Time 07:45AM | Arrival Time 08:25PM | Duration 12h40 | Departure days Sat | Cheapest price CHF39 |
Operator Flixbus USA | Departure Time 09:30AM | Arrival Time 07:16PM | Duration 9h46 | Departure days Sun | Cheapest price CHF63 |
Operator Amtrak | Departure Time 05:26PM | Arrival Time 03:30AM | Duration 10h04 | Departure days Sat | Cheapest price CHF46 |
Operator Amtrak | Departure Time 06:13PM | Arrival Time 04:40AM | Duration 10h27 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price CHF47 |
Operator Amtrak | Departure Time 07:13PM | Arrival Time 05:40AM | Duration 10h27 | Departure days Thu, Fri | Cheapest price CHF47 |
Operator Greyhound | Departure Time 07:40PM | Arrival Time 05:05AM | Duration 9h25 | Departure days Wed, Fri | Cheapest price CHF39 |
Operator Greyhound USA | Departure Time 11:05PM | Arrival Time 08:13AM | Duration 9h08 | Departure days Sun | Cheapest price CHF91 |
Live departures
Los Angeles, CA to South San Francisco, CA bus times
The table below shows live departures for Los Angeles, CA to South San Francisco, CA buses for today, Sunday, August 23. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:30 AM Los Angeles, CA | 9h46 | 7:16 PM South San Francisco, CA | 3 transfers | |
![]() | 9:30 AM Los Angeles, CA | 9h46 | 7:16 PM South San Francisco, CA | 2 transfers | |
![]() | 11:05 PM Los Angeles, CA | 9h08 | 8:13 AM South San Francisco, CA | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Los Angeles, CA to South San Francisco, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Aug 24
Aug 25
Aug 26
Aug 27
Aug 28
Aug 29
Aug 30
Why should you book Los Angeles, CA to South San Francisco, CA buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Los Angeles, CA to South San Francisco, CA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Los Angeles, CA to South San Francisco, CA.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Los Angeles, CA to South San Francisco, CA.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Los Angeles, CA to South San Francisco, CA.
Journey information
Overview: Bus from Los Angeles, CA to South San Francisco, CA
Buses from Los Angeles, CA to South San Francisco, CA run on average 19 times per day, taking around 9h 36m. Cheap bus tickets for this journey start at CHF34 if you book in advance.
There are 4 buses per day. The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 341 miles (549 km) distance in 7h 25m.
Distance 341 miles (549 km) |
Average bus duration 9h 36m |
Cheapest ticket price CHF34 |
Buses per day 19 |
Direct buses 4 |
Fastest bus 7h 25m |
First bus 12:15 AM |
Last bus 11:55 PM |
Cheapest Month Nov |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Oct - Dec |
Best time to book 14 days |
Bus providers: Greyhound, FlixBus from Los Angeles, CA to South San Francisco, CAYou can travel by bus between Los Angeles, CA to South San Francisco, CA with Greyhound, FlixBus for as low as CHF34. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Los Angeles, CA to South San Francisco, CA
Find answers to the most common questions about traveling from Los Angeles, CA to South San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Los Angeles, CA to South San Francisco, CA
Most Los Angeles, CA to South San Francisco, CA buses use the Los Angeles, Patsaouras Transit Plaza (Union Station) to San Francisco, Transit Center Bay 29 station pair. Use this guide to compare Los Angeles, CA and South San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Los Angeles, CA station do buses to South San Francisco, CA leave from?
Getting to Los Angeles, Patsaouras Transit Plaza (Union Station) from Los Angeles city centre
Los Angeles, Patsaouras Transit Plaza (Union Station) is 1 km from Los Angeles city centre. Public transport options include:
Los Angeles, Patsaouras Transit Plaza (Union Station) bus station facilities and services
Los Angeles, Patsaouras Transit Plaza (Union Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Food court and various dining options available.
Wi-Fi and ATMs
Wi-Fi available in main waiting areas. ATMs are aTMs available near main concourse.
Tickets and information
Ticket office support is available at Los Angeles, Patsaouras Transit Plaza (Union Station).
Parking, taxis and toilets
Available at Los Angeles, Patsaouras Transit Plaza (Union Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Los Angeles, Patsaouras Transit Plaza (Union Station): Station fully accessible with elevators and ramps.
Getting to Los Angeles, Cesar E Chavez / Vignes from Los Angeles city centre
Los Angeles, Cesar E Chavez / Vignes is 1 km from Los Angeles city centre. Public transport options include:
Los Angeles, Cesar E Chavez / Vignes bus station facilities and services
Los Angeles, Cesar E Chavez / Vignes has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Los Angeles, Cesar E Chavez / Vignes. ATMs are available at Los Angeles, Cesar E Chavez / Vignes.
Tickets and information
Ticket office support is available at Los Angeles, Cesar E Chavez / Vignes.
Parking, taxis and toilets
Available at Los Angeles, Cesar E Chavez / Vignes: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Los Angeles, Cesar E Chavez / Vignes: The station is accessible to people with disabilities.
Getting to Los Angeles, Gayley / Strathmore from Los Angeles city centre
Los Angeles, Gayley / Strathmore is 19 km from Los Angeles city centre. Public transport options include:
Los Angeles, Gayley / Strathmore bus station facilities and services
Los Angeles, Gayley / Strathmore has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Los Angeles, Gayley / Strathmore. ATMs are available at Los Angeles, Gayley / Strathmore.
Tickets and information
Ticket office support is available at Los Angeles, Gayley / Strathmore.
Parking, taxis and toilets
Available at Los Angeles, Gayley / Strathmore: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Los Angeles, Gayley / Strathmore: Basic accessibility features available for buses.
Most popular bus connections from Los Angeles, CA
More options for your journey from Los Angeles, CA to South San Francisco, CA
Here are some other resources that might have the information you need


