Journey information
Overview: Chicago, IL to South San Francisco, CA flight
Flights from Chicago, IL to South San Francisco, CA depart on average 62 times per day, taking around 13h 0m. Cheap flight tickets for this journey start at $218 (€178) but you can travel from only $160 (€131) by train.
There are 13 flights per day. The earliest flight runs at 00:43, the last at 23:57. The fastest flight covers the 1856 miles (2987 km) distance in 5h 1m. October is the cheapest month to fly.
Distance 1856 miles (2987 km) |
Average flight duration 13h 0m |
Cheapest ticket price $218 (€178) |
Flights per day 62 |
Direct flights 13 |
Fastest flight 5h 1m |
First flight 12:43 AM |
Last flight 11:57 PM |
Cheapest Month Oct |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jul - Sep |
Travel Information
Compare bus, train, and flight for Chicago, IL to South San Francisco, CA
Omio recommends booking the train as it is the most popular option from Chicago, IL to South San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $174. For those with little time consider booking a flight which can get you there in 13h 0m. The ticket price range depends on the travel mode: a bus costs an average of $174, and a train costs an average of $160.
Distance: 1856 miles (2987 km)
Compare flight with
| Flight | Most popular Train | Bus | Driving |
|---|---|---|---|
$227 Average price | $264 Average price | $222 Average price Cheapest | $433 Average price (fuel + tolls) |
16h 0m Average total duration Fastest 13h 0m Onboard + 3h 0m Additional time* | 53h 26m Average total duration 52h 56m Onboard + 30m Additional time* | 55h 1m Average total duration 54h 31m Onboard + 30m Additional time* | 31h 20m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Chicago, IL to South San Francisco, CA:
A bus is $5 (€4) less than a flight for this route with tickets for a flight from Chicago, IL to South San Francisco, CA costing on average $227 (€186).
A bus is $41 (€34) less than a train for this route with tickets for a train from Chicago, IL to South San Francisco, CA costing on average $264 (€215).
Other travel options to South San Francisco, CA take longer:
Train takes on average 52h 56m.
Bus takes on average 54h 31m.
Compare prices and tickets Chicago, IL to South San Francisco, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Chicago, IL to South San Francisco, CA Flight
Find answers to the most common questions about traveling from Chicago, IL to South San Francisco, CA by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

popular airports
Popular airports from Chicago, IL to South San Francisco, CA
- Free Wi-Fi available throughout the airport
- Shops are located in all terminals, including duty-free and brands like Hudson and MAC Cosmetics
- Parking available with options including hourly, daily, and economy lots, approximately 2.85€ ($3) per hour
- Restaurants are located in all terminals, offering a variety of cuisines including American and intertiol. Top options include Tortas Frontera and Publican Tavern.
- Available outside the terminal
- Elevators, ramps, toilets
- Available throughout the airport
- Hotels such as Hilton Chicago O'Hare are located on airport grounds, with others like the Hyatt Regency nearby.
- Showers are available in some lounges, such as the United Club, but access may require a fee or membership
- Lounges available, including United Club and American Airlines Admirals Club
- Lost and Found located in terminal 1, near the baggage claim area
- Car rental services are available at the Multi-Modal Facility, with companies like Hertz and Avis
- CTA Blue Line, O'Hare Station, 45 minutes to city center
More options for your journey from Chicago, IL to South San Francisco, CA
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