Compare prices and tickets Chicago, IL to South San Francisco, CA by train
Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Chicago, IL to South San Francisco, CA
Take a train from Chicago, IL to South San Francisco, CA and enjoy the approximately 1856 miles (2987 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
There are 1 trains per day. The earliest train runs at 06:55, the last at 21:41.
Distance 1856 miles (2987 km) |
Average train duration 52h 56m |
Trains per day 13 |
Direct trains 1 |
First train 06:55 |
Last train 21:41 |
Cheapest month Apr |
Cheapest day Wed |
High season Oct - Dec |
Low season Jul - Sep |
Train companies: Amtrak from Chicago, IL to South San Francisco, CA trainsAmtrak trains will get you between Chicago, IL and South San Francisco, CA. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Chicago, IL to South San Francisco, CA
Find answers to the most common questions about traveling from Chicago, IL to South San Francisco, CA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Chicago, IL to South San Francisco, CA
- 5:00 AM - 12:00 AM Monday - Sunday
- Free
- The car park is open 7 days a week from 5:00 a.m. to 12:00 a.m. Departures can be made outside of opening hours. Access via Canal Street.
- The Chicago Firehouse Restaurant
- Lou Mitchell's
- Outside the main entrance.
- Elevators, ramps, restrooms.
- $1
- The Kimpton Gray Hotel
- JW Marriott Chicago
- W Chicago - City Center
- Located in the main hall
- Located in the main hall
- Avis
- Budget
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, Amtrak services
- Hall 2: Metra services
- Hall 3: food court and retail shops
- Bus: Several lines available
- CTA: Blue Line, Pink Line
Most popular train connections from Chicago, IL
More options for your journey from Chicago, IL to South San Francisco, CA
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