San Diego, CA to South San Francisco, CA bus

Fri, Nov 07
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
SARFA S.L.
1,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
SARFA S.L.
1,000+ travel companies
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Travel Information

Compare bus, train, and flight for San Diego, CA to South San Francisco, CA

Omio recommends booking the bus as it is the most popular option from San Diego, CA to South San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from €60. For those with little time consider booking a flight which can get you there in 1h 32m. The ticket price range depends on the travel mode: a bus costs an average of €60, and a flight costs an average of €125.

Distance: 451 miles (727 km)

Compare bus with

Most popular
Bus
Flight
Train

€60

Average price

Cheapest

€125

Average price

€96

Average price

14h 9m

Average total duration

13h 39m

Onboard

+

30m

Additional time*

4h 32m

Average total duration

Fastest

1h 32m

Onboard

+

3h 0m

Additional time*

14h 56m

Average total duration

14h 26m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Direct Options

Compare prices and tickets San Diego, CA to South San Francisco, CA by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Nov 07
Sat
Nov 08
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Nov 09
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Nov 10
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Nov 11
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Nov 12
Thu
Nov 13

Journey information

Overview: Bus from San Diego, CA to South San Francisco, CA

USAUSA
USAUSA
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Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
451 miles (727 km)
Average bus duration
13h 39m
Cheapest ticket price
$73 (€60)
Buses per day
30
Direct buses
4
Fastest bus
13h 39m
First bus
04:01
Last bus
23:25

Key Takeaways

Train Ticket Prices
  • Budget Options: Train tickets from San Diego, CA to South San Francisco, CA start from as low as $73 (€60) if booked well in advance.
  • Standard Fares: Typically, trains cost $73 (€60) depending on the train type and class.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from San Diego, CA to South San Francisco, CA

Find answers to the most common questions about traveling from San Diego, CA to South San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

FAQs
The first bus from San Diego, CA to South San Francisco, CA leaves at 4: 55AM. Plan your trip with the Journey Planner   from Omio.
The last bus from San Diego, CA to South San Francisco, CA leaves at 11: 30PM.
A day trip to South San Francisco, CA from San Diego, CA is worth doing with a journey time of min each way. Check with Omio app   the best way to travel.
No, the bus from San Diego, CA to South San Francisco, CA has no accessibility options.
No, there are no bathrooms on board the bus from San Diego, CA to South San Francisco, CA.
No, bikes are not allowed on board the bus from San Diego, CA to South San Francisco, CA.

To find the cheapest bus tickets for your trip from San Diego, CA to South San Francisco, CA, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from San Diego, CA to South San Francisco, CA.
    No, luggage for the bus from San Diego, CA to South San Francisco, CA needs to be booked in addition.
    No, there are no additional luggage options for the bus from San Diego, CA to South San Francisco, CA.
    Unfortunately, pets are not allowed on the bus from San Diego, CA to South San Francisco, CA.
    No, there are no USB plugs on board the bus from San Diego, CA to South San Francisco, CA.
    No, there is no WiFi on board the bus from San Diego, CA to South San Francisco, CA.

    popular bus stations

    Popular bus stations from San Diego, CA to South San Francisco, CA

    San Diego
    South San Francisco
    San Diego, San Ysidro Transit Center
    information
    San Diego, Congress Street (Old Town Park)
    information
    San Diego, West Harbor Drive (The Headquarters at Seaport District)
    information
    HomeBusesBuses in USASan Diego, CA to South San Francisco, CA bus

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