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Travel Information
Compare bus, train, and flight for San Diego, CA to South San Francisco, CA
Omio recommends booking the train as it is the most popular option from San Diego, CA to South San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $72. For those with little time consider booking a flight which can get you there in 2h 28m. The ticket price range depends on the travel mode: a bus costs an average of $72, and a flight costs an average of $116.
Distance: 451 miles (727 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$86 Average price Cheapest | $97 Average price | $226 Average price |
14h 6m Average total duration 13h 36m Onboard + 30m Additional time* | 14h 37m Average total duration 14h 7m Onboard + 30m Additional time* | 5h 28m Average total duration Fastest 2h 28m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets San Diego, CA to South San Francisco, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from San Diego, CA to South San Francisco, CA
USAUSA
Buses from San Diego, CA to South San Francisco, CA run on average 20 times per day, taking around 13h 36m. Cheap bus tickets for this journey start at $72 (€59) if you book in advance.
There are 2 buses per day. The earliest bus runs at 04:01, the last at 23:25. The fastest bus covers the 451 miles (727 km) distance in 13h 20m.
Distance 451 miles (727 km) |
Average bus duration 13h 36m |
Cheapest ticket price $72 (€59) |
Buses per day 20 |
Direct buses 2 |
Fastest bus 13h 20m |
First bus 4:01 AM |
Last bus 11:25 PM |
FAQs: Bus from San Diego, CA to South San Francisco, CA
Find answers to the most common questions about traveling from San Diego, CA to South San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.
popular bus stations
Popular bus stations from San Diego, CA to South San Francisco, CA
More options for your journey from San Diego, CA to South San Francisco, CA
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Most popular buses to and from South San Francisco, CA and San Diego, CA
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