- Must visit
Vatican Museums
One of the world’s greatest museum complexes, known for classical sculpture, Renaissance masterpieces, and the Sistine Chapel. Advance booking is strongly recommended due to very high demand.
Omio recommends booking the bus as it is the most popular option from Castelvetrano to Rome among Omio's users. If you are prioritising price take the ferry with prices starting from $68. For those with little time consider booking a flight which can get you there in 1h 12m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a ferry costs an average of $68, and a train costs an average of $68.
Distance: 291 miles (469 km)
Most popular Bus | Flight | Train | Ferry | Driving |
|---|---|---|---|---|
$76 Average price | $74 Average price | $100 Average price | $68 Average price Cheapest | $57 Average price (fuel + tolls) |
14h 22m Average total duration 13h 52m Onboard + 30m Additional time* | 4h 12m Average total duration Fastest 1h 12m Onboard + 3h 0m Additional time* | 17h 5m Average total duration 16h 35m Onboard + 30m Additional time* | 15h 0m Average total duration 14h 0m Onboard + 1h 0m Additional time* | 11h 8m Average total duration (door-to-door) |
0.5 - 1.2kg CO2 emissions | 1.4 - 2.8kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Castelvetrano to Rome:
A ferry is $5 (€4) less than a flight for this route with tickets for a flight from Castelvetrano to Rome costing on average $74 (€60).
A ferry is $7 (€6) less than a bus for this route with tickets for a bus from Castelvetrano to Rome costing on average $76 (€62).
A ferry is $31 (€25) less than a train for this route with tickets for a train from Castelvetrano to Rome costing on average $100 (€81).
Other travel options to Rome take longer:
Bus takes on average 13h 52m.
Ferry takes on average 14h 0m.
Train takes on average 16h 35m.
You'll arrive about -3h -44m sooner (13h 52m by bus vs 11h 8m by car) and save roughly $-18.95 (€-15.50) compared to fuel and tolls ($76 (€62) vs $57 (€46)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by Autoservizi Salemi, BlaBlaCar.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Compare bus, train, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Castelvetrano to Rome run on average 1 times per day, taking around 13h 52m. Cheap bus tickets for this journey start at $76 (€62) but you can travel from only $25 (€20) by flight.
There are 1 buses per day. The earliest bus runs at 03:25, the last at 21:20. The fastest bus covers the 291 miles (469 km) distance in 15h 30m.
Distance 291 miles (469 km) |
Average bus duration 13h 52m |
Cheapest ticket price $76 (€62) |
Buses per day 1 |
Direct buses 1 |
Fastest bus 15h 30m |
First bus 3:25 AM |
Last bus 9:20 PM |
Cheapest Month May |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sat |
Best time to book 35 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
One of the world’s greatest museum complexes, known for classical sculpture, Renaissance masterpieces, and the Sistine Chapel. Advance booking is strongly recommended due to very high demand.
A celebrated villa museum with major works by Bernini, Caravaggio, and Canova, set inside Villa Borghese gardens. Timed-entry tickets are required and usually need advance reservation.
The city’s historic civic museums on Capitoline Hill, featuring Roman bronzes, sculpture, paintings, and superb views over the Forum area.
A grand Baroque square lined with fountains, churches, and elegant facades. It remains one of Rome’s classic walking and people-watching spots.
A famous monumental staircase linking Piazza di Spagna with Trinità dei Monti, popular for photos, shopping nearby, and city atmosphere.
A characterful district of narrow lanes, ivy-covered facades, and lively evening atmosphere, widely loved for wandering and street photography.
A classic Roman pasta with Pecorino Romano and black pepper. It is one of the city’s most iconic dishes for its simplicity and bold flavor.
Traditional Roman pasta made with guanciale, egg yolk, Pecorino Romano, and black pepper. It is a defining dish of Rome and should not contain cream.
Pasta with tomato, guanciale, Pecorino Romano, and chili. Though linked with Amatrice, it is a staple on Roman menus and deeply rooted in local cooking.
A historic trattoria near the Pantheon, respected for traditional Roman dishes such as carbonara, amatriciana, and seasonal specialties in an intimate atmosphere.
A celebrated central Rome dining room and delicatessen known for classic Roman pasta, cured meats, and an exceptional wine list in a lively upscale setting.
A famous Trastevere trattoria known for authentic Roman comfort food, including cacio e pepe, meatballs, and artichokes, with a classic casual feel.
Moderate for Western Europe: food and coffee can be reasonable, but hotels and major tourist areas cost more.
Service is often included or modest. Locals may round up or leave EUR 1-2 for coffee, 5-10% for good restaurant service; tips are appreciated, not required.
Official public transport app
Rome, Via Marsala / Viale Enrico De Nicola -> Roma Termini
Find answers to the most common questions about traveling from Castelvetrano to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Castelvetrano to Rome buses use the Castelvetrano, Via dei Caduti di Nassyria (Oasi Bar) to Roma, Autostazione Tiburtina station pair. Use this guide to compare Castelvetrano and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
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