Travel Information
Compare train, bus, and flight for Genoa to Lyon
Omio recommends booking the bus as it is the most popular option from Genoa to Lyon among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $48 For those with little time, consider booking a train, which has an average total journey time of 8h 12m. Average ticket prices depend on the travel mode: a bus costs an average of $48, while a train costs an average of $171.
Distance: 219 miles (354 km)
Compare bus with
Most popular Bus | Train | Driving |
|---|---|---|
$48 Average price Cheapest | $171 Average price | $237 Average price (fuel + tolls) |
8h 13m Average total duration 7h 43m Onboard + 30m Additional time* | 8h 12m Average total duration Fastest 7h 42m Onboard + 30m Additional time* | 5h 53m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Genoa to Lyon:
A bus is $123 less than a train for this route with tickets for a train from Genoa to Lyon costing on average $171.
A bus is $167 less than a flight for this route with tickets for a flight from Genoa to Lyon costing on average $215.
Other travel options to Lyon take longer:
Bus takes on average 8h 13m.
Flight takes on average 12h 37m.
Tickets start at around $48 compared to roughly $237 in fuel and tolls — a saving of about $188. The journey takes 7h 43m versus 5h 53m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Genoa to Lyon
How to get from Genoa to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Genoa to Lyon is by taking a bus because it’s the best combination of price and speed.
FlixBus2:10 AM6h35Genova, Via Fanti D'Italia8:45 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$551One-way0 transfers
Cheapest
FlixBus2:10 AM6h35Genova, Via Fanti D'Italia8:45 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$551One-way0 transfers
Fastest
LH1893+
LH41986:00 AM6h20Genoa Airport12:20 PMLyon Saint Exupery Airport$3931One-way1 transfer
Other options
FlixBus10:20 AM7h50Genova, Via Fanti D'Italia6:10 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$721One-way0 transfers
4731 · 5807411:55 PM11h55Genova, Via Fanti D'Italia11:50 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$731One-way1 transfer
4705 · 47686:10 PM12h35Genova, Via Fanti D'Italia6:45 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$731One-way1 transfer
VY6011 · VY122210:05 AM7h55Genoa Airport6:00 PMLyon Saint Exupery Airport$3201One-way1 transfer
LH1893+
LH97 · LH10766:00 AM7h20Genoa Airport1:20 PMLyon Saint Exupery Airport$3671One-way2 transfers
LH1893+
LH22526:00 AM13h25Genoa Airport7:25 PMLyon Saint Exupery Airport$3931One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Genoa to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Genoa to Lyon.

This is compared to other travel options from Genoa to Lyon:
A bus is $123 less than a train for this route with tickets for a train from Genoa to Lyon costing on average $171.
A bus is $167 less than a flight for this route with tickets for a flight from Genoa to Lyon costing on average $215.
Other travel options to Lyon take longer:
Bus takes on average 8h 13m.
Flight takes on average 12h 37m.
- Around 14 flights per day.
- Around 11 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Genoa and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Genoa Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Genoa Piazza Principe and arrive in Lyon Part Dieu.
- Buses mostly depart from Genova, Via Fanti D'Italia and arrive in Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
- Travel with FlixBus, BlaBlaCar Bus, BlaBlaCar to go to Lyon by bus.
- Travel with SNCF | TGV INOUI, Trenitalia, SNCF TER | Operated by SNCF Voyageurs 1187, Regionale to go to Lyon by train.
- 4 direct buses per day with FlixBus, BlaBlaCar Bus, BlaBlaCar.
Travelling from Genoa to Lyon: related information
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