- Must visit
Musée des Confluences
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
Cheapest price
$148
Average price
$155
Fastest journey
7 h 13 m
Average duration
8 h 57 m
Trains per day
9
Distance
354 km
The best way to find a cheap train ticket from Genoa to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Genoa to Lyon will cost around $155 if you buy it on the day, but the cheapest tickets can be found for only $148.
It's difficult to get from Genoa to Lyon without transferring at least once.
Regionale Veloce 3019+
FRECCIAROSSA 1000 9296
Regionale Veloce 3028+
FRECCIAROSSA 1000 9296
Intercity 658+
FRECCIAROSSA 1000 9296
Intercity 631+
FRECCIAROSSA 1000 9296
Intercity 662+
FRECCIAROSSA 1000 9296
Intercity 745+
FRECCIAROSSA 1000 9296
Intercity 666+
FRECCIAROSSA 1000 9296
Regionale Veloce 3028+
FRECCIAROSSA 1000 9296
Intercity 631+
FRECCIAROSSA 1000 9296
Intercity 662+
FRECCIAROSSA 1000 9296Omio recommends booking the bus as it is the most popular option from Genoa to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $22. For those with little time consider booking a train which can get you there in 7h 40m. The ticket price range depends on the travel mode: a bus costs an average of $22, and a flight costs an average of $117.
Distance: 219 miles (354 km)
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$124 Average price | $42 Average price Cheapest | $373 Average price | $238 Average price (fuel + tolls) |
8h 10m Average total duration Fastest 7h 40m Onboard + 30m Additional time* | 8h 13m Average total duration 7h 43m Onboard + 30m Additional time* | 18h 17m Average total duration 15h 17m Onboard + 3h 0m Additional time* | 5h 53m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Genoa to Lyon:
A bus is $82 (€66) less than a train for this route with tickets for a train from Genoa to Lyon costing on average $124 (€100).
A bus is $331 (€267) less than a flight for this route with tickets for a flight from Genoa to Lyon costing on average $373 (€301).
Other travel options to Lyon take longer:
Bus takes on average 7h 43m.
Flight takes on average 15h 17m.
Tickets start at around $124 (€100) compared to roughly $238 (€192) in fuel and tolls — a saving of about $114 (€92). The journey takes 7h 40m versus 5h 53m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Genoa to Lyon trains for today, Wednesday, June 3. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Intercity 652+ FRECCIAROSSA 1000 9296 | 6:44 AM Genoa Piazza Principe | 13h48 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Regionale Veloce 3019+ FRECCIAROSSA 1000 9296 | 7:50 AM Genoa Piazza Principe | 12h42 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Intercity 658+ FRECCIAROSSA 1000 9296 | 8:19 AM Genoa Piazza Principe | 12h13 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Intercity 662+ FRECCIAROSSA 1000 9296 | 9:18 AM Genoa Piazza Principe | 11h14 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Regionale Veloce 3028+ FRECCIAROSSA 1000 9296 | 11:42 AM Genoa Piazza Principe | 8h50 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Intercity 745+ FRECCIAROSSA 1000 9296 | 1:19 PM Genoa Piazza Principe | 7h13 | 8:32 PM Lyon Part Dieu | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Genoa to Lyon run on average 1 times per day, taking around 7h 40m. Cheap train tickets for this journey start at $74 (€60) but you can travel from only $22 (€18) by bus.
The earliest train runs at 00:25, the last at 22:22. The fastest train covers the 219 miles (354 km) distance in 6h 48m.
Distance 219 miles (354 km) |
Average train duration 7h 40m |
Cheapest ticket price $74 (€60) |
Trains per day 1 |
Fastest train 6h 48m |
First train 12:25 AM |
Last train 10:22 PM |
Cheapest Month May |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Thu |
Best time to book 49 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
Lyon’s premier fine arts museum, housed in a former abbey near Place des Terreaux. Known for strong collections of painting, sculpture, antiquities, and decorative arts.
Museum of Roman Lyon paired with the city’s ancient theaters on Fourvière hill. A key stop for understanding Lugdunum, the Roman origins of Lyon.
Lyon’s atmospheric old quarter with Renaissance lanes, traboules, and riverfront views. It is the city’s classic strolling area and a top priority for first-time visitors.
One of Europe’s largest open squares and a central meeting point in Lyon. It is a practical orientation stop and a key place for city views toward Fourvière.
Lyon’s flagship urban park with broad walking paths, lake, botanical areas, and a zoo. It is one of the best places in the city for relaxation and scenic walks.
Light dumplings made with pike and panade, usually baked in a rich Nantua crayfish sauce. A classic Lyonnais bouchon specialty.
A traditional salad of frisée lettuce with lardons, croutons, and a poached egg. It is one of the city’s most iconic starter dishes.
Lyon’s famous sausage baked inside a soft brioche dough. It is a beloved charcuterie-based specialty found in many bouchons.
A landmark fine dining institution in Lyon, famed for historic prestige and elegant cuisine rooted in the city’s gastronomic heritage.
The city’s celebrated covered food market, ideal for sampling oysters, charcuterie, cheese, pastries, and many iconic Lyonnais products.
A respected traditional restaurant associated with chef Joseph Viola, celebrated for refined Lyonnais classics in a polished but welcoming setting.
Moderate for France: bakeries and bouchons are fair value, while central hotels and fine dining cost more.
Service is included by law. Leaving small change or 5-10% for great service is appreciated, not required. Round up for taxis.
Official public transport app
Lyon Part-Dieu -> Bellecour, Lyon
Find answers to the most common questions about traveling from Genoa to Lyon by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

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