- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Cheapest price on Sep 02
$187
Average ticket price on Sep 02
$193
Fastest journey on Sep 02
6 h 48 m
Average journey duration on Sep 02
8 h 3 m
Trains on Sep 02
10
Distance
354 km
The best way to find a cheap train ticket from Genoa to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Genoa to Lyon will cost around $193 if you buy it on the day, but the cheapest tickets can be found for only $187.
It's difficult to get from Genoa to Lyon without transferring at least once.
Regionale Veloce 3019+
FRECCIAROSSA 1000 9296
Regionale Veloce 3028+
FRECCIAROSSA 1000 9296
Regionale Veloce 3032+
FRECCIAROSSA 1000 9296
Intercity 658+
FRECCIAROSSA 1000 9296
Intercity 745+
FRECCIAROSSA 1000 9296
Regionale Veloce 3032+
FRECCIAROSSA 1000 9296
Intercity 745+
FRECCIAROSSA 1000 9296
Intercity 666+
FRECCIAROSSA 1000 9296
Regionale Veloce 3028+
FRECCIAROSSA 1000 9296
Intercity 631+
FRECCIAROSSA 1000 9296Omio recommends booking the bus as it is the most popular option from Genoa to Lyon among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $49 For those with little time, consider booking a train, which has an average total journey time of 8h 12m. Average ticket prices depend on the travel mode: a bus costs an average of $49, while a flight costs an average of $218.
Distance: 219 miles (354 km)
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$173 Average price | $49 Average price Cheapest | $218 Average price | $239 Average price (fuel + tolls) |
8h 12m Average total duration Fastest 7h 42m Onboard + 30m Additional time* | 8h 13m Average total duration 7h 43m Onboard + 30m Additional time* | 12h 37m Average total duration 10h 37m Onboard + 2h 0m Additional time* | 5h 53m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Genoa to Lyon:
A bus is $124 (€100) less than a train for this route with tickets for a train from Genoa to Lyon costing on average $173 (€140).
A bus is $169 (€137) less than a flight for this route with tickets for a flight from Genoa to Lyon costing on average $218 (€176).
Other travel options to Lyon take longer:
Bus takes on average 7h 43m.
Flight takes on average 10h 37m.
Tickets start at around $173 (€140) compared to roughly $239 (€194) in fuel and tolls — a saving of about $66 (€54). The journey takes 7h 42m versus 5h 53m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Genoa to Lyon trains for tomorrow, Wednesday, September 2. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Intercity 652+ FRECCIAROSSA 1000 9296 | 6:44 AM Genoa Piazza Principe | 13h48 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Intercity 653+ FRECCIAROSSA 1000 9296 | 7:19 AM Genoa Piazza Principe | 13h13 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Regionale Veloce 3019+ FRECCIAROSSA 1000 9296 | 7:50 AM Genoa Piazza Principe | 12h42 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Intercity 658+ FRECCIAROSSA 1000 9296 | 8:19 AM Genoa Piazza Principe | 12h13 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Intercity 662+ FRECCIAROSSA 1000 9296 | 9:18 AM Genoa Piazza Principe | 11h14 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Intercity 631+ FRECCIAROSSA 1000 9296 | 11:19 AM Genoa Piazza Principe | 9h13 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Regionale Veloce 3028+ FRECCIAROSSA 1000 9296 | 11:42 AM Genoa Piazza Principe | 8h50 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Intercity 666+ FRECCIAROSSA 1000 9296 | 12:19 PM Genoa Piazza Principe | 8h13 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Intercity 745+ FRECCIAROSSA 1000 9296 | 1:19 PM Genoa Piazza Principe | 7h13 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Regionale Veloce 3032+ FRECCIAROSSA 1000 9296 | 1:44 PM Genoa Piazza Principe | 6h48 | 8:32 PM Lyon Part Dieu | 1 transfer | |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Genoa to Lyon run on average 1 times per day, taking around 7h 42m. Cheap train tickets for this journey start at $95 (€77) but you can travel from only $28 (€23) by bus.
The earliest train runs at 00:25, the last at 22:22. The fastest train covers the 219 miles (354 km) distance in 6h 48m.
Distance 219 miles (354 km) |
Average train duration 7h 42m |
Cheapest ticket price $95 (€77) |
Trains per day 1 |
Fastest train 6h 48m |
First train 12:25 AM |
Last train 10:22 PM |
Cheapest Month May |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Mon |
Best time to book 1 day |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Museum of cinema miniatures and film props in Vieux Lyon. Popular for detailed sets, special-effects history, and family-friendly exhibits.
Excellent free natural history and ethnography museum with fossils, animals, and global cultures. A strong local favorite, especially for families.
Renaissance quarter with cobbled lanes, traboules, courtyards, and major monuments. Essential for atmosphere, history, and walking exploration.
Central peninsula between the Rhône and Saône, packed with elegant streets, squares, shopping, and many of Lyon’s classic city views.
Historic silk-workers’ hill district with stairways, murals, markets, and hidden passageways. Great for local character and city panoramas.
Pike dumplings in a rich crayfish sauce. A Lyon classic from traditional bouchons, prized for its delicate fish texture and luxurious sauce.
Crisp salad of frisée, bacon lardons, croutons, and a poached egg. A staple Lyonnaise bistro dish that reflects the city's hearty cooking style.
Slow-cooked onions with vinegar, often served warm or chilled. This old Lyonnais side dish is traditional in bouchons and pairs well with charcuterie.
Refined dining by Paul Bocuse, known for polished French cuisine and iconic Lyon dishes in an elegant, historic dining room.
Well-known traditional bouchon in Vieux Lyon, praised for generous Lyonnais specialties and a lively old-city atmosphere.
Historic bouchon near Place Bellecour serving quenelles, salade lyonnaise, and classic regional fare in a warm traditional setting.
Moderate for Western Europe: hotels and dining are mid-priced, while public transport is good value for visitors.
Service is usually included. Round up or leave 5-10% for great restaurant service. Round up taxi fares; small change is fine in cafes.
Find answers to the most common questions about traveling from Genoa to Lyon by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most Genoa to Lyon trains use the Genova Piazza Principe to Lyon Part Dieu station pair. Use this guide to compare Genoa and Lyon train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Genova Piazza Principe is 1 km from Genoa city centre. Public transport options include:
Genova Piazza Principe has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Ristorante Salgari, Trattoria dell'Acciughetta
Free. ATMs are available in the train station.
Ticket office support is available at Genova Piazza Principe. Information desks are located in the main hall.
Luggage storage is available at Genova Piazza Principe. Lost and found is available at the station.
Available at Genova Piazza Principe: Parking, Taxis, WC.
Available at Genova Piazza Principe: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Genova Piazza Principe: Elevators, ramps.
Nearby hotels include Hotel Continental Genova, Grand Hotel Savoia, Hotel Britannia.
Genova Brignole is 1 km from Genoa city centre. Public transport options include:
Genova Brignole has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Ristorante Pizzeria da Toto, Trattoria Rosmarino
Free. ATMs are available in the train station.
Ticket office support is available at Genova Brignole. Information desks are located in the main hall.
Luggage storage is available at Genova Brignole. Lost and found is available at the station.
Available at Genova Brignole: Parking, Taxis, WC.
Available at Genova Brignole: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Genova Brignole: Elevators, ramps, restrooms.
Nearby hotels include Hotel Bristol Palace, NH Genova Centro, Best Western Hotel Moderno Verdi.
Genova Sampierdarena is 3 km from Genoa city centre. Public transport options include:
Genova Sampierdarena has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Information Desk, and Luggage Carts.
Food options include: Zenzero, Trattoria da Mario
Free. ATMs are available in the train station.
Ticket office support is available at Genova Sampierdarena. Information desks are located in the main hall.
Luggage storage is available at Genova Sampierdarena. Lost and found is available at the station.
Available at Genova Sampierdarena: Parking, Taxis, WC.
Available at Genova Sampierdarena: Bike Parking, Bike Rental.
Accessibility facilities are available at Genova Sampierdarena: Ramps.
Nearby hotels include Hotel Galata, Hotel Bellevue, Hotel Helvetia.
Lyon Part Dieu is 1 km from Lyon city centre. Public transport options include:
Lyon Part Dieu has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Alto Café, Paul, Paul The Café, Starbucks, Exki, Sushi Shop, Carrefour
Free unlimited WiFi. ATMs are located in the station's main hall.
The ticket office is open Mon - Wed: 05:00 - 20:45, Thu - Sat: 05:00 - 21:45, Sun: 06:45 - 21:45. Information desks are located in the station's main hall. .
Luggage storage is luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk. .
Available at Lyon Part Dieu: Parking, Taxis, WC.
Available at Lyon Part Dieu: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Lyon Part Dieu: Complimentary personalized care is available.
Nearby hotels include Radisson Blu Hotel Lyon, Mercure Lyon Center, ibis Styles Lyon Center.
Here are some other resources that might have the information you need