- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey on Place des Terreaux, known for strong collections from antiquity to modern art.
Cheapest price
$54
Average price
$69
Fastest journey
6 h 35 m
Average duration
7 h 55 m
Buses per day
12
Distance
354 km
The best way to find a cheap bus ticket from Genoa to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Genoa to Lyon will cost around $69 if you buy it on the day, but the cheapest tickets can be found for only $54.
Of the 12 buses that leave Genoa for Lyon on Fri, Jun 19, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jun 19 the direct buses cover the 354 km distance in an average of 7 h 55 m but if you time it right, some buses will get you there in just 6 h 35 m .
On Fri, Jun 19 the slowest buses will take 8 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
50106
4705 · 4768
FlixBus
FlixBus
FlixBus
FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the bus as it is the most popular option from Genoa to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $22. For those with little time consider booking a train which can get you there in 7h 40m. The ticket price range depends on the travel mode: a bus costs an average of $22, and a flight costs an average of $115.
Distance: 219 miles (354 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$42 Average price Cheapest | $123 Average price | $367 Average price | $235 Average price (fuel + tolls) |
8h 13m Average total duration 7h 43m Onboard + 30m Additional time* | 8h 10m Average total duration Fastest 7h 40m Onboard + 30m Additional time* | 18h 17m Average total duration 15h 17m Onboard + 3h 0m Additional time* | 5h 53m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Genoa to Lyon:
A bus is $81 (€66) less than a train for this route with tickets for a train from Genoa to Lyon costing on average $123 (€100).
A bus is $326 (€267) less than a flight for this route with tickets for a flight from Genoa to Lyon costing on average $367 (€301).
Other travel options to Lyon take longer:
Bus takes on average 7h 43m.
Flight takes on average 15h 17m.
Tickets start at around $42 (€34) compared to roughly $235 (€192) in fuel and tolls — a saving of about $193 (€158). The journey takes 7h 43m versus 5h 53m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar Bus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:10AM | Arrival Time 08:45AM | Duration 6h35 | Departure days Everyday | Cheapest price $43 |
Operator BlaBlaCar Bus | Departure Time 05:00AM | Arrival Time 05:05PM | Duration 12h05 | Departure days Mon, Fri, Sat, Sun | Cheapest price $41 |
Operator FlixBus | Departure Time 05:00AM | Arrival Time 02:10PM | Duration 9h10 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $61 |
Operator FlixBus | Departure Time 05:20AM | Arrival Time 02:10PM | Duration 8h50 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $62 |
Operator FlixBus | Departure Time 06:40AM | Arrival Time 03:05PM | Duration 8h25 | Departure days Sat, Sun | Cheapest price $61 |
Operator FlixBus | Departure Time 10:20AM | Arrival Time 06:10PM | Duration 7h50 | Departure days Everyday | Cheapest price $46 |
Operator BlaBlaCar Bus | Departure Time 02:00PM | Arrival Time 12:20AM | Duration 10h20 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $38 |
Operator FlixBus | Departure Time 03:05PM | Arrival Time 01:25AM | Duration 10h20 | Departure days Everyday | Cheapest price $68 |
Operator FlixBus | Departure Time 03:15PM | Arrival Time 10:40PM | Duration 7h25 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $40 |
Operator BlaBlaCar Bus | Departure Time 03:45PM | Arrival Time 04:05AM | Duration 12h20 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $71 |
Operator BlaBlaCar Bus | Departure Time 06:10PM | Arrival Time 06:45AM | Duration 12h35 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $43 |
Operator FlixBus | Departure Time 07:55PM | Arrival Time 03:55AM | Duration 8h00 | Departure days Everyday | Cheapest price $60 |
Operator BlaBlaCar Bus | Departure Time 11:55PM | Arrival Time 01:40PM | Duration 13h45 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $59 |
The table below shows live departures for Genoa to Lyon buses for today, Thursday, June 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
4705 · 4768 | 6:10 PM Genova, Via Fanti D'Italia | 12h35 | 6:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 7:55 PM Genova, Via Fanti D'Italia | 9h00 | 4:55 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
4731 · 58074 | 11:55 PM Genova, Via Fanti D'Italia | 11h55 | 11:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| Friday, June 19 | |||||
FlixBus | 2:10 AM Genova, Via Fanti D'Italia | 6h35 | 8:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus · FlixBus | 5:00 AM Genoa, Piazza della Vittoria | 9h10 | 2:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
4732 · 94766 | 5:00 AM Genova, Via Fanti D'Italia | 12h05 | 5:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 5:20 AM Genova, Via Fanti D'Italia | 8h50 | 2:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 10:20 AM Genova, Via Fanti D'Italia | 7h50 | 6:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
50106 | 2:00 PM Genova, Via Fanti D'Italia | 10h20 | 12:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 3:05 PM Genova, Via Fanti D'Italia | 10h20 | 1:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 3:15 PM Genova, Via Fanti D'Italia | 7h25 | 10:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
4704 · 51511 | 3:45 PM Genova, Via Fanti D'Italia | 11h25 | 3:10 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Genoa to Lyon run on average 10 times per day, taking around 7h 43m. Cheap bus tickets for this journey start at $22 (€18) if you book in advance.
There are 4 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 219 miles (354 km) distance in 6h 35m.
Distance 219 miles (354 km) |
Average bus duration 7h 43m |
Cheapest ticket price $22 (€18) |
Buses per day 10 |
Direct buses 4 |
Fastest bus 6h 35m |
First bus 12:05 AM |
Last bus 11:55 PM |
Cheapest Month Oct |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Thu |
Best time to book 35 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey on Place des Terreaux, known for strong collections from antiquity to modern art.
Excellent museum on Roman Lyon with mosaics, inscriptions, and artifacts beside the ancient theaters on Fourvière hill.
Striking science and society museum at the meeting of the Rhône and Saône, famous for immersive displays and architecture.
The city's atmospheric old quarter with Renaissance lanes, traboules, courtyards, and a strong UNESCO heritage feel.
One of Europe's largest open squares and a key central meeting point in Lyon's Presqu'île.
Large urban park with lake, botanical spaces, greenhouses, and broad paths for walking and relaxing.
Light dumplings traditionally made with pike and baked in a rich Nantua crayfish sauce, a classic specialty of Lyonnais cuisine.
A warm salad of frisee lettuce, lardons, croutons, and a poached egg, emblematic of Lyon's hearty bouchon cooking.
Pork sausage baked inside a soft brioche loaf, a festive and traditional Lyonnais dish often served in bouchons.
An iconic fine-dining restaurant with deep Lyon culinary heritage, serving elegant cuisine in a prestigious setting.
A respected modern bouchon offering refined takes on Lyonnais classics in a warm and polished setting.
A historic bouchon known for classic Lyonnais dishes, convivial service, and a traditional, bustling atmosphere.
Moderate by French standards: bakeries and lunch deals are good value, while central hotels and dinner spots cost more.
Service is included by law. Rounding up or leaving 5-10% for very good restaurant service is appreciated, not required. Round up taxis; small change is fine in cafés and bars.
Official public transport app
Lyon Perrache Bus Station, Lyon -> Lyon Part-Dieu Station, Lyon
Find answers to the most common questions about traveling from Genoa to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most Genoa to Lyon buses use the Genova, Via Fanti D'Italia to Lyon, Gare Routière de Perrache station pair, with some services arriving at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan). Use this guide to compare Genoa and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Here are some other resources that might have the information you need