Travel Information
Compare train, bus, and flight for Genoa to Brussels
Omio recommends booking the flight as it is the most popular option from Genoa to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $75. For those with little time consider booking a flight which can get you there in 2h 43m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.8 - 2.0kg. The ticket price range depends on the travel mode: a bus costs an average of $75, and a train costs an average of $180.
Distance: 493 miles (794 km)
Compare flight with
Most popular Flight | Bus | Train |
|---|---|---|
$163 Average price | $116 Average price Cheapest | $273 Average price |
5h 43m Average total duration Fastest 2h 43m Onboard + 3h 0m Additional time* | 19h 30m Average total duration 19h 0m Onboard + 30m Additional time* | 17h 48m Average total duration 17h 18m Onboard + 30m Additional time* |
2.4 - 4.8kg CO2 emissions | 0.8 - 2.0kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Genoa to Brussels:
A bus is $48 (€38) less than a flight for this route with tickets for a flight from Genoa to Brussels costing on average $163 (€132).
A bus is $157 (€126) less than a train for this route with tickets for a train from Genoa to Brussels costing on average $273 (€220).
Other travel options to Brussels take longer:
Train takes on average 17h 18m.
Bus takes on average 19h 0m.
Travel optionsfrom Genoa to Brussels
How to get from Genoa to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Genoa to Brussels is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus10:20 AM21h55Genova, Via Fanti D'Italia8:15 AMBrussels, Brussels South (Gare du Midi)$991One-way1 transfer
Cheapest
FlixBus · FlixBus10:20 AM21h55Genova, Via Fanti D'Italia8:15 AMBrussels, Brussels South (Gare du Midi)$991One-way1 transfer
Fastest
FlixBus · FlixBus · FlixBus7:55 PM19h50Genova, Via Fanti D'Italia3:45 PMBrussels, Brussels South (Gare du Midi)$1261One-way2 transfers
Other options
50106 · 16572:00 PM22h00Genova, Via Fanti D'Italia12:00 PMBrussels, Brussels South (Gare du Midi)$1101One-way1 transfer
FlixBus · FlixBus · FlixBus3:40 PM21h05Genova, Via Fanti D'Italia12:45 PMBrussels, Brussels South (Gare du Midi)$1111One-way2 transfers
FlixBus · FlixBus · FlixBus5:20 AM21h45Genova, Via Fanti D'Italia3:05 AMBrussels, Brussels South (Gare du Midi)$1131One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Genoa to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Genoa to Brussels.

This is compared to other travel options from Genoa to Brussels:
A bus is $48 (€38) less than a flight for this route with tickets for a flight from Genoa to Brussels costing on average $163 (€132).
A bus is $157 (€126) less than a train for this route with tickets for a train from Genoa to Brussels costing on average $273 (€220).
Other travel options to Brussels take longer:
Train takes on average 17h 18m.
Bus takes on average 19h 0m.
- Around 33 flights per day.
- Around 6 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Genoa and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.
- Buses mostly depart from Genova, Via Fanti D'Italia and arrive in Brussels, Brussels South (Gare du Midi).
- Flights mostly depart from Genoa Airport and arrive in Brussels Airport.
- Travel with Ryanair, Brussels Airlines, KLM Cityhopper, ITA, Lufthansa Cityline, Lufthansa, Vueling to go to Brussels by flight.
- Travel with Regionale to go to Brussels by train.
- Travel with FlixBus, BlaBlaCar Bus to go to Brussels by bus.
- 0 direct flights per day with Ryanair.
- 0 direct buses per day with FlixBus.
Travelling from Genoa to Brussels: related information
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