Travel Information
Compare train, bus, and flight for Genoa to Brussels
Omio recommends booking the flight as it is the most popular option from Genoa to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $112 For those with little time, consider booking a flight, which has an average total journey time of 4h 46m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.8 - 2.0kg. Average ticket prices depend on the travel mode: a bus costs an average of $112, while a train costs an average of $272.
Distance: 493 miles (794 km)
Compare flight with
Most popular Flight | Bus | Train |
|---|---|---|
$153 Average price | $112 Average price Cheapest | $272 Average price |
4h 46m Average total duration Fastest 2h 46m Onboard + 2h 0m Additional time* | 19h 34m Average total duration 19h 4m Onboard + 30m Additional time* | 17h 48m Average total duration 17h 18m Onboard + 30m Additional time* |
2.4 - 4.8kg CO2 emissions | 0.8 - 2.0kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Genoa to Brussels:
A bus is $41 (€33) less than a flight for this route with tickets for a flight from Genoa to Brussels costing on average $153 (€124).
A bus is $160 (€129) less than a train for this route with tickets for a train from Genoa to Brussels costing on average $272 (€220).
Other travel options to Brussels take longer:
Train takes on average 17h 48m.
Bus takes on average 19h 34m.
Travel optionsfrom Genoa to Brussels
How to get from Genoa to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Genoa to Brussels is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus · FlixBus7:55 PM22h00Genova, Via Fanti D'Italia5:55 PMBrussels, Brussels South (Gare du Midi)$801One-way2 transfers
Cheapest
FlixBus · FlixBus · FlixBus7:55 PM22h00Genova, Via Fanti D'Italia5:55 PMBrussels, Brussels South (Gare du Midi)$801One-way2 transfers
Fastest
LH6921+
LH56301:15 PM4h00Genoa Airport5:15 PMBrussels Airport$4301One-way1 transfer
Other options
FlixBus · FlixBus · FlixBus3:40 PM21h05Genova, Via Fanti D'Italia12:45 PMBrussels, Brussels South (Gare du Midi)$811One-way2 transfers
FlixBus · FlixBus · FlixBus5:25 AM21h40Genova, Via Fanti D'Italia3:05 AMBrussels, Brussels South (Gare du Midi)$811One-way2 transfers
FlixBus · FlixBus · FlixBus5:00 AM22h05Genoa, Piazza della Vittoria3:05 AMBrussels, Brussels South (Gare du Midi)$821One-way2 transfers
AZ1392 · AZ1567:20 PM15h25Genoa Airport10:45 AMBrussels Airport$1221One-way1 transfer
AZ1384 · AZ16011:20 AM6h35Genoa Airport5:55 PMBrussels Airport$1661One-way1 transfer
AZ1380 · AZ1606:50 AM11h05Genoa Airport5:55 PMBrussels Airport$1661One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Genoa to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Genoa to Brussels.

This is compared to other travel options from Genoa to Brussels:
A bus is $41 (€33) less than a flight for this route with tickets for a flight from Genoa to Brussels costing on average $153 (€124).
A bus is $160 (€129) less than a train for this route with tickets for a train from Genoa to Brussels costing on average $272 (€220).
Other travel options to Brussels take longer:
Train takes on average 17h 48m.
Bus takes on average 19h 34m.
- Around 32 flights per day.
- Around 6 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Genoa and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.
- Buses mostly depart from Genova, Via Fanti D'Italia and arrive in Brussels, Brussels South (Gare du Midi).
- Flights mostly depart from Genoa Airport and arrive in Brussels Airport.
- Travel with FlixBus, BlaBlaCar Bus to go to Brussels by bus.
- Travel with Regionale to go to Brussels by train.
- Travel with Ryanair, Brussels Airlines, KLM Cityhopper, Vueling, ITA, Lufthansa Cityline to go to Brussels by flight.
- 0 direct buses per day with FlixBus.
Travelling from Genoa to Brussels: related information
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