Travel Information
Compare train, bus, and flight for Genoa to Madrid
Omio recommends booking the flight as it is the most popular option from Genoa to Madrid among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €134 For those with little time, consider booking a flight, which has an average total journey time of 6h 40m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 1.1 - 2.8kg. Average ticket prices depend on the travel mode: a bus costs an average of €134, while a flight costs an average of €430.
Distance: 700 miles (1127 km)
Compare flight with
Most popular Flight | Bus | Driving |
|---|---|---|
€430 Average price | €134 Average price Cheapest | €326 Average price (fuel + tolls) |
6h 40m Average total duration Fastest 4h 40m Onboard + 2h 0m Additional time* | 25h 31m Average total duration 25h 1m Onboard + 30m Additional time* | 14h 42m Average total duration (door-to-door) |
3.4 - 6.8kg CO2 emissions | 1.1 - 2.8kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Genoa to Madrid:
A bus is €296 less than a flight for this route with tickets for a flight from Genoa to Madrid costing on average €430.
Other travel options to Madrid take longer:
Bus takes on average 25h 31m.
Tickets start at around €134 compared to roughly €326 in fuel and tolls — a saving of about €192. The journey takes 25h 1m versus 14h 42m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Genoa to Madrid
How to get from Genoa to Madrid by train, bus or flight.
Our recommendation
The best way to travel from Genoa to Madrid is by taking a bus because it’s the best combination of price and speed.
Normal · Normal11:55 PM24h25Genova, Via Fanti D'Italia12:20 AMMadrid, Intercambiador de Avenida de América€801One-way1 transfer
Cheapest
Normal · Normal11:55 PM24h25Genova, Via Fanti D'Italia12:20 AMMadrid, Intercambiador de Avenida de América€801One-way1 transfer
Fastest
V718163:30 PM2h15Genoa Airport5:45 PMMadrid Barajas Airport€1791One-way0 transfers
Other options
4704 · 43493:45 PM25h00Genova, Via Fanti D'Italia4:45 PMMadrid, Estación Sur de Autobuses€841One-way1 transfer
50106 · 43492:00 PM26h45Genova, Via Fanti D'Italia4:45 PMMadrid, Estación Sur de Autobuses€841One-way1 transfer
FlixBus1:30 PM21h00Genova, Via Fanti D'Italia10:30 AMMadrid, Estación Sur de Autobuses€881One-way0 transfers
Regionale Veloce 3016 · S1 TRENORD 24118+
W46313+
Regionale TRENORD 3195:44 AM9h46Genoa Piazza Principe3:30 PMMadrid Barajas Airport€2531One-way3 transfers
Regionale Veloce 3016+
Regionale TRENORD 2926+
W463135:44 AM9h46Genoa Piazza Principe3:30 PMMadrid Barajas Airport€2531One-way2 transfers
FlixBus+
VY6341 · VY10128:00 AM12h00Genova, Via Fanti D'Italia8:00 PMMadrid Barajas Airport€2641One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Genoa to Madrid
Travel to Madrid easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Genoa to Madrid.

This is compared to other travel options from Genoa to Madrid:
A bus is €296 less than a flight for this route with tickets for a flight from Genoa to Madrid costing on average €430.
Other travel options to Madrid take longer:
Bus takes on average 25h 31m.
- Around 40 flights per day.
- Around 7 buses per day.
However, we recommend checking specific travel dates for your route between Genoa and Madrid as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Genoa Airport and arrive in Madrid Barajas Airport.
- Buses mostly depart from Genova, Via Fanti D'Italia and arrive in Madrid, Estación Sur de Autobuses.
- Travel with FlixBus, Alsa, BlaBlaCar Bus to go to Madrid by bus.
- Travel with Lufthansa Cityline, asl airlines, Air Europa, Swiss, Brussels Airlines, Lufthansa City Airlines, Air France, KLM, Lufthansa, Helvetic Airways, Volotea, ITA to go to Madrid by flight.
- 1 direct buses per day with FlixBus.
- 0 direct flights per day with Volotea.
Travelling from Genoa to Madrid: related information
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