Travel Information
Compare train and bus for Genoa to Karlsruhe
Omio recommends booking the bus as it is the most popular option from Genoa to Karlsruhe among Omio's users. If you are prioritising price, take the train, with an average ticket price of $40 For those with little time, consider booking a train, which has an average total journey time of 12h 9m. Average ticket prices depend on the travel mode: a train costs an average of $40, while a bus costs an average of $98.
Distance: 318 miles (513 km)
Compare bus with
Most popular Bus | Train | Driving |
|---|---|---|
$98 Average price | $40 Average price Cheapest | $207 Average price (fuel + tolls) |
12h 30m Average total duration 12h 0m Onboard + 30m Additional time* | 12h 9m Average total duration Fastest 11h 39m Onboard + 30m Additional time* | 7h 51m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Genoa to Karlsruhe:
A train is $58 less than a bus for this route with tickets for a bus from Genoa to Karlsruhe costing on average $98.
Other travel options to Karlsruhe take longer:
Bus takes on average 12h 30m.
Tickets start at around $98 compared to roughly $207 in fuel and tolls — a saving of about $109. The journey takes 12h 0m versus 7h 51m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Genoa to Karlsruhe
How to get from Genoa to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Genoa to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
FlixBus9:30 PM10h50Genova, Via Fanti D'Italia8:20 AMKarlsruhe Hbf$551One-way0 transfers
Cheapest
FlixBus9:30 PM10h50Genova, Via Fanti D'Italia8:20 AMKarlsruhe Hbf$551One-way0 transfers
Fastest
KL1646 · KL1821+
ICE 2032:05 PM6h54Genoa Airport8:59 PMKarlsruhe Hbf$5431One-way2 transfers
Other options
Regionale Veloce 3016 · Regionale TRENORD 2615+
RJ 86 · ICE 2665:44 AM14h08Genoa Piazza Principe7:52 PMKarlsruhe Hbf$1361One-way3 transfers
Intercity 652+
Regionale Veloce 2357 · Regionale TRENORD 2617+
RJ 866:44 AM13h08Genoa Piazza Principe7:52 PMKarlsruhe Hbf$1381One-way4 transfers
FRECCIAROSSA 9710+
RJ 86 · ICE 2667:05 AM12h47Genoa Piazza Principe7:52 PMKarlsruhe Hbf$1481One-way2 transfers
FlixBus · FlixBus+
FlixTrain9:30 PM12h53Genova, Via Fanti D'Italia10:23 AMKarlsruhe Hbf$601One-way2 transfers
FlixBus · FlixBus4:40 PM11h05Genova, Via Fanti D'Italia3:45 AMKarlsruhe Hbf$601One-way1 transfer
AZ1384+
AZ7294+
ICE 20511:20 AM11h39Genoa Airport10:59 PMKarlsruhe Hbf$3201One-way2 transfers
AZ1384+
AZ7294+
ICE 20311:20 AM9h39Genoa Airport8:59 PMKarlsruhe Hbf$3221One-way2 transfers
AZ1384+
AZ7294+
ICE 613 · ICE 37711:20 AM8h39Genoa Airport7:59 PMKarlsruhe Hbf$3291One-way3 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Oct 08
Oct 09
Oct 10
Oct 11
Oct 12
Oct 13
Oct 14
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Genoa to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Genoa to Karlsruhe.

This is compared to other travel options from Genoa to Karlsruhe:
A train is $58 less than a bus for this route with tickets for a bus from Genoa to Karlsruhe costing on average $98.
Other travel options to Karlsruhe take longer:
Bus takes on average 12h 30m.
- Around 6 trains per day.
- Around 4 buses per day.
However, we recommend checking specific travel dates for your route between Genoa and Karlsruhe as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Genoa Piazza Principe and arrive in Karlsruhe Hbf.
- Buses mostly depart from Genova, Via Fanti D'Italia and arrive in Karlsruhe Hbf.
- Travel with FlixBus, BlaBlaCar Bus to go to Karlsruhe by bus.
- Travel with Deutsche Bahn to go to Karlsruhe by train.
- 1 direct buses per day with FlixBus.
Travelling from Genoa to Karlsruhe: related information
Here are some other resources that might have the information you need
