Travel Information
Compare train, bus, and flight for Avignon to Brussels
Omio recommends booking the train as it is the most popular option from Avignon to Brussels among Omio's users. If you are prioritising price take the flight with prices starting from $23. For those with little time consider booking a flight which can get you there in 2h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.7kg. The ticket price range depends on the travel mode: a flight costs an average of $23, and a train costs an average of $48.
Distance: 477 miles (768 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$190 Average price | $79 Average price | $78 Average price Cheapest | $267 Average price (fuel + tolls) |
5h 15m Average total duration 4h 45m Onboard + 30m Additional time* | 13h 17m Average total duration 12h 47m Onboard + 30m Additional time* | 5h 21m Average total duration Fastest 2h 21m Onboard + 3h 0m Additional time* | 9h 38m Average total duration (door-to-door) |
0.2 - 0.7kg CO2 emissions Lowest | 0.8 - 1.9kg CO2 emissions | 2.3 - 4.6kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Avignon to Brussels:
A flight is $1 (€1) less than a bus for this route with tickets for a bus from Avignon to Brussels costing on average $79 (€65).
A flight is $113 (€92) less than a train for this route with tickets for a train from Avignon to Brussels costing on average $190 (€156).
Other travel options to Brussels take longer:
Train takes on average 4h 45m.
Bus takes on average 12h 47m.
Travel optionsfrom Avignon to Brussels
How to get from Avignon to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Avignon to Brussels is by taking a flight because it’s the best combination of price and speed.
FR 48231:15 PM1h45Beziers Cap d'Agde Airport3:00 PMBrussels South Charleroi Airport$481One-way0 transfers
Cheapest
FR 48231:15 PM1h45Beziers Cap d'Agde Airport3:00 PMBrussels South Charleroi Airport$481One-way0 transfers
Fastest
FR 48231:15 PM1h45Beziers Cap d'Agde Airport3:00 PMBrussels South Charleroi Airport$481One-way0 transfers
Other options
17702+
98642:10 PM6h46Avignon Centre8:56 PMBrussels-Midi$1561One-way1 transfer
886188+
98824:13 PM6h43Avignon Centre10:56 PMBrussels-Midi$1621One-way1 transfer
17700+
98628:10 AM7h16Avignon Centre3:26 PMBrussels-Midi$1681One-way1 transfer
FlixBus · FlixBus3:35 PM16h40Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)8:15 AMBrussels, Brussels South (Gare du Midi)$991One-way1 transfer
FlixBus · FlixBus11:45 PM16h05Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)3:50 PMBrussels, Gare Du Midi$1051One-way1 transfer
FlixBus · FlixBus11:45 PM13h55Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)1:40 PMBrussels, Brussels South (Gare du Midi)$1111One-way1 transfer
886561+
SN35988:32 AM6h43Avignon Centre3:15 PMBrussels Airport$2881One-way1 transfer
17701+
LX581+
LX7889:51 AM8h44Avignon Centre6:35 PMBrussels Airport$3311One-way2 transfers
879625+
LX581+
LX7888:51 AM9h44Avignon Centre6:35 PMBrussels Airport$3311One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Avignon to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Avignon to Brussels.

This is compared to other travel options from Avignon to Brussels:
A flight is $1 (€1) less than a bus for this route with tickets for a bus from Avignon to Brussels costing on average $79 (€65).
A flight is $113 (€92) less than a train for this route with tickets for a train from Avignon to Brussels costing on average $190 (€156).
Other travel options to Brussels take longer:
Train takes on average 4h 45m.
Bus takes on average 12h 47m.
- Around 11 flights per day.
- Around 9 buses per day.
- Around 6 trains per day.
However, we recommend checking specific travel dates for your route between Avignon and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Marseille Provence Airport and arrive in Brussels Airport.
- Trains mostly depart from Avignon TGV and arrive in Brussels-Midi.
- Buses mostly depart from Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle) and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with Ryanair, Malta Air, Brussels Airlines, Vueling, Lufthansa to go to Brussels by flight.
- Travel with BlaBlaCar Bus, FlixBus, BlaBlaCar, Alsa to go to Brussels by bus.
- Travel with TGV, SNCF | TGV INOUI, Eurostar to go to Brussels by train.
- 3 direct flights per day with Ryanair, Malta Air, Brussels Airlines.
- 0 direct buses per day with BlaBlaCar.
- 2 direct trains per day with TGV, SNCF | TGV INOUI, Eurostar.
Travelling from Avignon to Brussels: related information
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