Travel Information
Compare train, bus, and flight for Avignon to Brussels
Omio recommends booking the flight as it is the most popular option from Avignon to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €88 For those with little time, consider booking a flight, which has an average total journey time of 4h 13m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.7kg. Average ticket prices depend on the travel mode: a bus costs an average of €88, while a flight costs an average of €229.
Distance: 477 miles (768 km)
Compare flight with
Most popular Flight | Train | Bus |
|---|---|---|
€229 Average price | €93 Average price | €88 Average price Cheapest |
4h 13m Average total duration Fastest 2h 13m Onboard + 2h 0m Additional time* | 5h 4m Average total duration 4h 34m Onboard + 30m Additional time* | 14h 9m Average total duration 13h 39m Onboard + 30m Additional time* |
2.3 - 4.6kg CO2 emissions | 0.2 - 0.7kg CO2 emissions Lowest | 0.8 - 1.9kg CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Avignon to Brussels
How to get from Avignon to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Avignon to Brussels is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus11:45 PM16h05Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)3:50 PMBrussels, Gare Du Midi€401One-way1 transfer
Cheapest
FlixBus · FlixBus11:45 PM16h05Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)3:50 PMBrussels, Gare Du Midi€401One-way1 transfer
Fastest
FR 48231:15 PM1h45Beziers Cap d'Agde Airport3:00 PMBrussels South Charleroi Airport€501One-way0 transfers
Other options
6124+
94894:41 PM5h44Avignon TGV10:25 PMBrussels-Midi€1331One-way1 transfer
6124+
93894:41 PM5h44Avignon TGV10:25 PMBrussels-Midi€1331One-way1 transfer
6122+
94813:41 PM5h06Avignon TGV8:47 PMBrussels-Midi€1381One-way1 transfer
58074 · 503378:30 AM15h05Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)11:35 PMBrussels, Brussels South (Gare du Midi)€451One-way1 transfer
FlixBus · FlixBus11:45 PM13h55Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)1:40 PMBrussels, Brussels South (Gare du Midi)€501One-way1 transfer
FlixBus · FlixBus3:35 PM16h40Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)8:15 AMBrussels, Brussels South (Gare du Midi)€511One-way1 transfer
886561+
SN35988:32 AM6h43Avignon Centre3:15 PMBrussels Airport€2381One-way1 transfer
879533+
KL1470 · KL170711:53 AM10h22Avignon Centre10:15 PMBrussels Airport€2421One-way2 transfers
886565+
KL1470 · KL170711:16 AM10h59Avignon Centre10:15 PMBrussels Airport€2421One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Avignon to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Avignon to Brussels.

This is compared to other travel options from Avignon to Brussels:
A bus is €5 less than a train for this route with tickets for a train from Avignon to Brussels costing on average €93.
A bus is €140 less than a flight for this route with tickets for a flight from Avignon to Brussels costing on average €229.
Other travel options to Brussels take longer:
Train takes on average 5h 4m.
Bus takes on average 14h 9m.
- Around 23 trains per day.
- Around 9 buses per day.
- Around 2 flights per day.
However, we recommend checking specific travel dates for your route between Avignon and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Beziers Cap d'Agde Airport and arrive in Brussels South Charleroi Airport.
- Trains mostly depart from Avignon TGV and arrive in Brussels-Midi.
- Buses mostly depart from Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle) and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with FlixBus, BlaBlaCar Bus to go to Brussels by bus.
- Travel with SNCF | TGV INOUI, TER to go to Brussels by train.
- Travel with Lufthansa Cityline, KLM Cityhopper, Brussels Airlines, KLM, Austrian Airlines, Lufthansa, Vueling, Helvetic Airways, Air Corsica, Ryanair to go to Brussels by flight.
- 2 direct trains per day with SNCF | TGV INOUI.
- 1 direct flights per day with Brussels Airlines, Ryanair.
Travelling from Avignon to Brussels: related information
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