The cheapest and fastest buses from Avignon to Brussels
Cheapest price
$92
Average price
$100
Fastest journey
10 h 10 m
Average duration
19 h 8 m
Buses per day
3
Distance
768 km
The best way to find a cheap bus ticket from Avignon to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Avignon to Brussels will cost around $100 if you buy it on the day, but the cheapest tickets can be found for only $92.
Of the 3 buses that leave Avignon for Brussels on Wed, Mar 18, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Mar 18 the direct buses cover the 768 km distance in an average of 19 h 8 m but if you time it right, some buses will get you there in just 10 h 10 m .
On Wed, Mar 18 the slowest buses will take 23 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBusTravel Information
Compare train, bus, and flight for Avignon to Brussels
Omio recommends booking the train as it is the most popular option from Avignon to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $53. For those with little time consider booking a flight which can get you there in 2h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.7kg. The ticket price range depends on the travel mode: a bus costs an average of $53, and a train costs an average of $67.
Distance: 477 miles (768 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$85 Average price Cheapest | $166 Average price | $103 Average price |
13h 6m Average total duration 12h 36m Onboard + 30m Additional time* | 5h 11m Average total duration 4h 41m Onboard + 30m Additional time* | 5h 21m Average total duration Fastest 2h 21m Onboard + 3h 0m Additional time* |
0.8 - 1.9kg CO2 emissions | 0.2 - 0.7kg CO2 emissions Lowest | 2.3 - 4.6kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Avignon to Brussels Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 08:45AM | Arrival Time 08:30AM | Duration 23h45 | Departure days Wed | Cheapest price $101 |
Operator BlaBlaCar | Departure Time 11:10AM | Arrival Time 09:20PM | Duration 10h10 | Departure days Wed | Cheapest price $92 |
Operator FlixBus | Departure Time 02:55PM | Arrival Time 03:50PM | Duration 24h55 | Departure days Tue | Cheapest price $75 |
Live departures
Avignon to Brussels bus times
The table below shows live departures for Avignon to Brussels buses for tomorrow, Tuesday, March 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 7:45 AM Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle) | 23h30 | 7:15 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus | 7:45 AM Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle) | 23h45 | 7:30 AM Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Avignon to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 18
Mar 19
Mar 20
Mar 21
Mar 22
Mar 23
Mar 24
Why should you book Avignon to Brussels buses with Omio?
Why book with Omio vs BlaBlaCar Bus?
- Compare with other providers: On Omio, you can not only buy tickets for BlaBlaCar Bus, but also compare tickets for the likes of FlixBus to find the best option for your trip from Avignon to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare BlaBlaCar Bus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Avignon to Brussels.
Why book with Omio over Checkmybus, Wanderu or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Avignon to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Avignon to Brussels.
Journey information
Overview: Bus from Avignon to Brussels
Buses from Avignon to Brussels run on average 9 times per day, taking around 12h 36m. Cheap bus tickets for this journey start at $53 (€43) but you can travel from only $25 (€20) by flight.
The earliest bus runs at 00:10, the last at 23:45. The fastest bus covers the 477 miles (768 km) distance in 13h 10m.
Distance 477 miles (768 km) |
Average bus duration 12h 36m |
Cheapest ticket price $53 (€43) |
Buses per day 9 |
Fastest bus 13h 10m |
First bus 00:10 |
Last bus 23:45 |
Cheapest month Sep |
Cheapest day Mon |
High season Jul - Sep |
Low season Jan - Mar |
Busiest day Sat |
Least busy day Sun |
Best day to book ahead 84 days |
Bus providers: BlaBlaCar Bus, FlixBus, BlaBlaCar from Avignon to BrusselsYou can travel by bus between Avignon to Brussels with BlaBlaCar Bus, FlixBus, BlaBlaCar for as low as $25 (€20). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar Bus
BlaBlaCar
FAQs: Bus from Avignon to Brussels
Find answers to the most common questions about traveling from Avignon to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Grand Place, a UNESCO World Heritage site known for its opulent guildhalls and vibrant flower market
- Atomium, an iconic structure and museum offering panoramic views of the city
- Manneken Pis, a famous bronze statue symbolizing the irreverent spirit of Brussels
- Royal Palace of Brussels, the official palace of the Belgian king with impressive architecture and gardens
- Magritte Museum, dedicated to the works of surrealist artist René Magritte, featuring an extensive collection of his paintings and drawings.
- Explore the vibrant Marolles district, known for its eclectic mix of antique shops and street art
- Enjoy a leisurely stroll through the picturesque Parc du Cinquantenaire, home to impressive arches and museums
- Sample Belgian chocolates at one of the city's renowned chocolatiers
- Discover the lively atmosphere of the Saint-Géry district, filled with trendy bars and cafes
- Attend a performance at the historic La Monnaie opera house, showcasing world-class productions.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Avignon to Brussels
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
- 06:00-23:59
- Free Wi-Fi
- Cafeteria Noord (in the station)
- Quick Brussels Noord (in the station)
- Le Pain Quotidien (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 14, 57, 58 Metro: 2, 6 Train: IC, S1, S2
Most popular bus connections from Avignon
More options for your journey from Avignon to Brussels
Here are some other resources that might have the information you need



