- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Cheapest price on Sep 07
$139
Average ticket price on Sep 07
$223
Fastest journey on Sep 07
4 h 54 m
Average journey duration on Sep 07
5 h 3 m
Trains on Sep 07
49
Distance
768 km
The best way to find a cheap train ticket from Avignon to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Avignon to Brussels will cost around $223 if you buy it on the day, but the cheapest tickets can be found for only $139.
On Mon, Sep 07, we found 49 trains from Avignon to Brussels, including 5 direct services.
On Mon, Sep 07 the direct trains cover the 768 km distance in an average of 5 h 3 m but if you time it right, some trains will get you there in just 4 h 54 m .
On Mon, Sep 07 the slowest trains will take 5 h 6 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
9882
6136+
9429
6136+
9333
6136+
9441
6136+
9341
9868
9854
6106+
9333
6106+
9333
6122+
9481Omio recommends booking the train as it is the most popular option from Avignon to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $88 For those with little time, consider booking a flight, which has an average total journey time of 4h 21m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.7kg. Average ticket prices depend on the travel mode: a bus costs an average of $88, while a train costs an average of $198.
Distance: 477 miles (768 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$198 Average price | $88 Average price Cheapest | $131 Average price | $272 Average price (fuel + tolls) |
5h 11m Average total duration 4h 41m Onboard + 30m Additional time* | 13h 6m Average total duration 12h 36m Onboard + 30m Additional time* | 4h 21m Average total duration Fastest 2h 21m Onboard + 2h 0m Additional time* | 9h 38m Average total duration (door-to-door) |
0.2 - 0.7kg CO2 emissions Lowest | 0.8 - 1.9kg CO2 emissions | 2.3 - 4.6kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Avignon to Brussels:
A bus is $42 (€34) less than a flight for this route with tickets for a flight from Avignon to Brussels costing on average $131 (€106).
A bus is $110 (€89) less than a train for this route with tickets for a train from Avignon to Brussels costing on average $198 (€160).
Other travel options to Brussels take longer:
Train takes on average 4h 41m.
Bus takes on average 12h 36m.
The journey is about 4h 57m faster (4h 41m by train vs 9h 38m by car) and roughly $74 (€60) cheaper once you factor in fuel and tolls ($198 (€160) vs $272 (€220)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Direct services run with SNCF | TGV INOUI, TGV, Eurostar.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
The table below shows live departures for Avignon to Brussels trains for today, Sunday, September 6. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
6124+ 9395 | On time 4:41 PM Avignon TGV | 6h36 | 11:17 PM Brussels-Midi | 1 transfer | |
6124+ 9489 | On time 4:41 PM Avignon TGV | 5h44 | 10:25 PM Brussels-Midi | 1 transfer | |
6124+ 9389 | On time 4:41 PM Avignon TGV | 5h44 | 10:25 PM Brussels-Midi | 1 transfer | |
6128+ 9395 | 6:14 PM Avignon TGV | 5h03 | 11:17 PM Brussels-Midi | 1 transfer | |
| Monday, September 7 | |||||
6136+ 9429 | 6:41 AM Avignon TGV | 5h36 | 12:17 PM Brussels-Midi | 1 transfer | |
6136+ 9333 | 6:41 AM Avignon TGV | 6h06 | 12:47 PM Brussels-Midi | 1 transfer | |
6136+ 9441 | 6:41 AM Avignon TGV | 7h36 | 2:17 PM Brussels-Midi | 1 transfer | |
6136+ 9341 | 6:41 AM Avignon TGV | 7h36 | 2:17 PM Brussels-Midi | 1 transfer | |
6136+ 9429 | 6:41 AM Avignon TGV | 5h36 | 12:17 PM Brussels-Midi | 1 transfer | |
6136+ 9333 | 6:41 AM Avignon TGV | 6h06 | 12:47 PM Brussels-Midi | 1 transfer | |
6136+ 9441 | 6:41 AM Avignon TGV | 7h36 | 2:17 PM Brussels-Midi | 1 transfer | |
6136+ 9341 | 6:41 AM Avignon TGV | 7h36 | 2:17 PM Brussels-Midi | 1 transfer | |
6136+ 9429 | 6:41 AM Avignon TGV | 5h33 | 12:14 PM Brussels-Midi | 1 transfer | |
9854+ 879309 | 6:46 AM Avignon Centre | 5h32 | 12:18 PM Brussels-Midi | 1 transfer | |
9854 | 7:15 AM Avignon TGV | 5h03 | 12:18 PM Brussels-Midi | 0 transfersDirect | |
6106+ 9441 | 7:41 AM Avignon TGV | 6h36 | 2:17 PM Brussels-Midi | 1 transfer | |
6106+ 9341 | 7:41 AM Avignon TGV | 6h36 | 2:17 PM Brussels-Midi | 1 transfer | |
6106+ 9333 | 7:41 AM Avignon TGV | 5h06 | 12:47 PM Brussels-Midi | 1 transfer | |
6106+ 9441 | 7:41 AM Avignon TGV | 6h36 | 2:17 PM Brussels-Midi | 1 transfer | |
6106+ 9333 | 7:41 AM Avignon TGV | 5h06 | 12:47 PM Brussels-Midi | 1 transfer | |
6106+ 9341 | 7:41 AM Avignon TGV | 6h36 | 2:17 PM Brussels-Midi | 1 transfer | |
9862+ 876409 | 8:34 AM Avignon Centre | 6h52 | 3:26 PM Brussels-Midi | 1 transfer | |
6112 · 7037 · 9862 | 9:41 AM Avignon TGV | 5h45 | 3:26 PM Brussels-Midi | 2 transfers | |
6112+ 9451 | 9:41 AM Avignon TGV | 6h03 | 3:44 PM Brussels-Midi | 1 transfer | |
6112+ 9481 | 9:41 AM Avignon TGV | 11h06 | 8:47 PM Brussels-Midi | 1 transfer | |
6112+ 9477 | 9:41 AM Avignon TGV | 10h44 | 8:25 PM Brussels-Midi | 1 transfer | |
6850 · 6618+ 9481 | 10:57 AM Avignon TGV | 9h50 | 8:47 PM Brussels-Midi | 2 transfers | |
6850 · 6618+ 9477 | 10:57 AM Avignon TGV | 9h28 | 8:25 PM Brussels-Midi | 2 transfers | |
6850 · 6618+ 9387 | 10:57 AM Avignon TGV | 10h47 | 9:44 PM Brussels-Midi | 2 transfers | |
9866+ 879694 | 12:16 PM Avignon Centre | 5h56 | 6:12 PM Brussels-Midi | 1 transfer | |
6116+ 9387 | 12:41 PM Avignon TGV | 9h03 | 9:44 PM Brussels-Midi | 1 transfer | |
6116+ 9477 | 12:41 PM Avignon TGV | 7h44 | 8:25 PM Brussels-Midi | 1 transfer | |
6116+ 9481 | 12:41 PM Avignon TGV | 8h06 | 8:47 PM Brussels-Midi | 1 transfer | |
9866 | 12:49 PM Avignon TGV | 5h23 | 6:12 PM Brussels-Midi | 0 transfersDirect | |
9866 · 6620+ 9481 | 12:49 PM Avignon TGV | 7h58 | 8:47 PM Brussels-Midi | 2 transfers | |
9866 · 6620+ 9477 | 12:49 PM Avignon TGV | 7h36 | 8:25 PM Brussels-Midi | 2 transfers | |
9866 · 6620+ 9387 | 12:49 PM Avignon TGV | 8h55 | 9:44 PM Brussels-Midi | 2 transfers | |
879342+ 86987+ 6204+ 9387 | 1:12 PM Avignon TGV | 8h32 | 9:44 PM Brussels-Midi | 3 transfers | |
879342+ 86987+ 6204+ 9477 | 1:12 PM Avignon TGV | 7h13 | 8:25 PM Brussels-Midi | 3 transfers | |
879342+ 86987+ 6204+ 9481 | 1:12 PM Avignon TGV | 7h35 | 8:47 PM Brussels-Midi | 3 transfers | |
6120+ 9481 | 2:41 PM Avignon TGV | 6h06 | 8:47 PM Brussels-Midi | 1 transfer | |
6120+ 9387 | 2:41 PM Avignon TGV | 7h03 | 9:44 PM Brussels-Midi | 1 transfer | |
6120+ 9477 | 2:41 PM Avignon TGV | 5h44 | 8:25 PM Brussels-Midi | 1 transfer | |
9868+ 879355 | 3:13 PM Avignon Centre | 5h30 | 8:43 PM Brussels-Midi | 1 transfer | |
6122+ 9481 | 3:41 PM Avignon TGV | 5h06 | 8:47 PM Brussels-Midi | 1 transfer | |
6122+ 9393 | 3:41 PM Avignon TGV | 7h15 | 10:56 PM Brussels-Midi | 1 transfer | |
6122+ 9387 | 3:41 PM Avignon TGV | 6h03 | 9:44 PM Brussels-Midi | 1 transfer | |
9868 | 3:49 PM Avignon TGV | 4h54 | 8:43 PM Brussels-Midi | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Avignon to Brussels run on average 6 times per day, taking around 4h 41m. Cheap train tickets for this journey start at $94 (€76) but you can travel from only $25 (€20) by flight.
There are 2 trains per day. The earliest train runs at 06:00, the last at 19:16. The fastest train covers the 477 miles (768 km) distance in 4h 52m.
Distance 477 miles (768 km) |
Average train duration 4h 41m |
Cheapest ticket price $94 (€76) |
Trains per day 6 |
Direct trains 2 |
Fastest train 4h 52m |
First train 6:00 AM |
Last train 7:16 PM |
Cheapest Month Jan |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Mon |
Best time to book 35 days |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
Official public transport app
Brussels-Midi -> Brussels-Central
Find answers to the most common questions about traveling from Avignon to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Most Avignon to Brussels trains use the Avignon TGV to Bruxelles-Midi station pair. Use this guide to compare Avignon and Brussels train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Avignon TGV is 3 km from Avignon city centre. Public transport options include:
Avignon TGV has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Starbucks, Eric Kayser, Selecta
Free, unlimited Wi-Fi is available throughout the station. ATMs are located on the south entrance of the station.
The ticket office is open Mon - Sun: 09:15 - 12:55, 14:00 - 17:30. Information desks are located at the ticket office in the departure hall.
Available at Avignon TGV: Parking, Taxis, WC.
Available at Avignon TGV: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Avignon TGV: Wheelchair access, personalized assistance service. Contact +33 890640650 or [email protected].
Nearby hotels include Aparthotel Adagio, Hôtel Mercure Avignon Gare TGV, Hôtel Kyriad Avignon Courtine Gare.
Avignon Centre has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Le Goût du Jour, Restaurant L'Essentiel
Free. ATMs are available in the train station.
Ticket office support is available at Avignon Centre. Information desks are located in the main hall.
Luggage storage is available at Avignon Centre. Lost and found is available at the station.
Available at Avignon Centre: Parking, Taxis, WC.
Available at Avignon Centre: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Avignon Centre: Elevators, ramps, restrooms.
Nearby hotels include Novotel Avignon Centre, Mercure Avignon Centre Palais des Papes Hotel, Hotel de l'Horloge.
Bruxelles-Midi has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Pullman Hotel Bar, Quick Gare du Midi, Subway, EXKi Zuid, Starbucks, Häagen-Dazs, Sbarro, The Coffee Club, The Belgian Chocolate House, PAUL, & many more
Wi-Fi is available for a fee. ATMs are available at Bruxelles-Midi.
Ticket office support is available at Bruxelles-Midi. Information desks are located in the main concourse and next to the international platforms.
Luggage storage is baggage storage facility is located across from the Thalys business lounge.
Available at Bruxelles-Midi: Parking, Taxis, WC.
Available at Bruxelles-Midi: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Bruxelles-Midi: Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
Nearby hotels include Les Lofts De Styliste, Park Inn by Radisson Brussels Midi, Pullman Brussels Centre Midi.
Here are some other resources that might have the information you need