The cheapest and fastest trains from Avignon to Brussels
Cheapest price
$125
Average price
$210
Fastest journey
4 h 57 m
Average duration
5 h 4 m
Trains per day
29
Distance
768 km
The best way to find a cheap train ticket from Avignon to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Avignon to Brussels will cost around $210 if you buy it on the day, but the cheapest tickets can be found for only $125.
Of the 29 trains that leave Avignon for Brussels on Tue, Mar 10, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Mar 10 the direct trains cover the 768 km distance in an average of 5 h 4 m but if you time it right, some trains will get you there in just 4 h 57 m .
On Tue, Mar 10 the slowest trains will take 5 h 6 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
9882
879365+
9882
879355+
9868 · 9882
876409+
9862
876409+
9862 · 9882
6102+
9321
6124+
9387
6122+
9481
6122+
9381
6116+
9363Travel Information
Compare train, bus, and flight for Avignon to Brussels
Omio recommends booking the train as it is the most popular option from Avignon to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $53. For those with little time consider booking a flight which can get you there in 2h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.7kg. The ticket price range depends on the travel mode: a bus costs an average of $53, and a train costs an average of $67.
Distance: 477 miles (768 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$166 Average price | $85 Average price Cheapest | $103 Average price |
5h 11m Average total duration 4h 41m Onboard + 30m Additional time* | 13h 6m Average total duration 12h 36m Onboard + 30m Additional time* | 5h 21m Average total duration Fastest 2h 21m Onboard + 3h 0m Additional time* |
0.2 - 0.7kg CO2 emissions Lowest | 0.8 - 1.9kg CO2 emissions | 2.3 - 4.6kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Avignon to Brussels train times
The table below shows live departures for Avignon to Brussels trains for tomorrow, Tuesday, March 10. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
6102+ 9321 | 4:52 AM Avignon TGV | 4h57 | 9:49 AM Brussels-Midi | 1 transfer | |
6194+ 9429 | 4:58 AM Avignon Centre | 6h19 | 11:17 AM Brussels-Midi | 1 transfer | |
6194+ 9329 | 4:58 AM Avignon Centre | 6h19 | 11:17 AM Brussels-Midi | 1 transfer | |
6136+ 9429 | 5:41 AM Avignon TGV | 5h36 | 11:17 AM Brussels-Midi | 1 transfer | |
6136+ 9329 | 5:41 AM Avignon TGV | 5h36 | 11:17 AM Brussels-Midi | 1 transfer | |
876409+ 9862 · 9864 | On time 7:34 AM Avignon Centre | 12h22 | 7:56 PM Brussels-Midi | 2 transfers | |
876409+ 9862 · 9868 | On time 7:34 AM Avignon Centre | 12h22 | 7:56 PM Brussels-Midi | 2 transfers | |
876409+ 9862 · 9882 | On time 7:34 AM Avignon Centre | 14h22 | 9:56 PM Brussels-Midi | 2 transfers | |
876409+ 9862 | On time 7:34 AM Avignon Centre | 6h52 | 2:26 PM Brussels-Midi | 1 transfer | |
9583 · 9862 | On time 7:48 AM Avignon TGV | 6h38 | 2:26 PM Brussels-Midi | 1 transfer | |
6112+ 9351 | 8:41 AM Avignon TGV | 6h07 | 2:48 PM Brussels-Midi | 1 transfer | |
6112+ 9451 | 8:41 AM Avignon TGV | 6h07 | 2:48 PM Brussels-Midi | 1 transfer | |
879694+ 9866 · 9868 | On time 11:16 AM Avignon Centre | 8h40 | 7:56 PM Brussels-Midi | 2 transfers | |
879694+ 9866 · 9864 | On time 11:16 AM Avignon Centre | 8h40 | 7:56 PM Brussels-Midi | 2 transfers | |
879694+ 9866 · 9882 | On time 11:16 AM Avignon Centre | 10h40 | 9:56 PM Brussels-Midi | 2 transfers | |
6116+ 9363 | 11:41 AM Avignon TGV | 5h06 | 4:47 PM Brussels-Midi | 1 transfer | |
6116+ 9463 | 11:41 AM Avignon TGV | 5h06 | 4:47 PM Brussels-Midi | 1 transfer | |
86987+ 5500 · 5192 · 9864 | On time 12:34 PM Avignon Centre | 7h22 | 7:56 PM Brussels-Midi | 3 transfers | |
86987+ 5500 · 5192 · 9868 | On time 12:34 PM Avignon Centre | 7h22 | 7:56 PM Brussels-Midi | 3 transfers | |
86987+ 5500 · 5192 · 9882 | On time 12:34 PM Avignon Centre | 9h22 | 9:56 PM Brussels-Midi | 3 transfers | |
6120+ 9375 | 1:41 PM Avignon TGV | 5h06 | 6:47 PM Brussels-Midi | 1 transfer | |
879355+ 9868 | On time 2:13 PM Avignon Centre | 5h43 | 7:56 PM Brussels-Midi | 1 transfer | |
879355+ 9868 · 9882 | On time 2:13 PM Avignon Centre | 7h43 | 9:56 PM Brussels-Midi | 2 transfers | |
6122+ 9481 | 2:41 PM Avignon TGV | 5h06 | 7:47 PM Brussels-Midi | 1 transfer | |
6122+ 9381 | 2:41 PM Avignon TGV | 5h06 | 7:47 PM Brussels-Midi | 1 transfer | |
9868 | On time 2:49 PM Avignon TGV | 5h07 | 7:56 PM Brussels-Midi | 0 transfersDirect | |
6124+ 9387 | 3:41 PM Avignon TGV | 5h03 | 8:44 PM Brussels-Midi | 1 transfer | |
879365+ 9882 | On time 4:13 PM Avignon Centre | 5h43 | 9:56 PM Brussels-Midi | 1 transfer | |
9882 | On time 4:49 PM Avignon TGV | 5h07 | 9:56 PM Brussels-Midi | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Avignon to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 09
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Mar 13
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Mar 15
Why should you book Avignon to Brussels trains with Omio?
Why book with Omio vs TGV?
- Compare with other providers: On Omio, you can not only buy tickets for TGV, but also compare tickets for the likes of TGV INOUI or Eurostar to find the best option for your trip from Avignon to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare TGV with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Avignon to Brussels.
Journey information
Overview: Train from Avignon to Brussels
Trains from Avignon to Brussels run on average 6 times per day, taking around 4h 41m. Cheap train tickets for this journey start at $67 (€55) but you can travel from only $25 (€20) by flight.
There are 2 trains per day. The earliest train runs at 06:00, the last at 19:16. The fastest train covers the 477 miles (768 km) distance in 4h 54m.
Distance 477 miles (768 km) |
Average train duration 4h 41m |
Cheapest ticket price $67 (€55) |
Trains per day 6 |
Direct trains 2 |
Fastest train 4h 54m |
First train 06:00 |
Last train 19:16 |
Cheapest month Mar |
Cheapest day Tue |
High season Jul - Sep |
Low season Jan - Mar |
Busiest day Sat |
Least busy day Sun |
Best day to book ahead 84 days |
Train companies: TGV, TGV INOUI, Eurostar from Avignon to Brussels trainsTGV, TGV INOUI, Eurostar trains will get you between Avignon and Brussels from $25 (€20). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
TGV
TGV INOUI
Eurostar
FAQs: Trains from Avignon to Brussels
Find answers to the most common questions about traveling from Avignon to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Avignon to Brussels
- Mon - Sun: 09:15 - 12:55, 14:00 - 17:30
- Free, unlimited Wi-Fi is available throughout the station.
- Starbucks
- Eric Kayser
- Selecta
- Wheelchair access, personalized assistance service. Contact +33 890640650 or [email protected].
- Aparthotel Adagio
- Hôtel Mercure Avignon Gare TGV
- Hôtel Kyriad Avignon Courtine Gare
- Mon - Sun: 09:15 - 12:55, 14:00 - 17:30
- Located at the ticket office in the departure hall.
- Bus lines: ORIZO line
- Train lines: TGV, TGV Lyria, TGV/ICE, TGV INOUI, OUIGO, Eurostar, Thalys, TER, AVE
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, with access from Rue Jean Jaurès.
- Restaurant Le Goût du Jour
- Restaurant L'Essentiel
- Outside the main entrance.
- Elevators, ramps, restrooms.
- €0.50
- Novotel Avignon Centre
- Mercure Avignon Centre Palais des Papes Hotel
- Hotel de l'Horloge
- Located in the main hall
- 200 places, covered
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-4 for regional and local trains
- Hall 2: ticket office and waiting area
- Bus: Several lines available
- Train: Connection to Avignon TGV station
- Mon - Sun: 05:45 - 21:30
- Wi-Fi is available for a fee.
- Baggage storage facility is located across from the Thalys business lounge.
- Pullman Hotel Bar
- Quick Gare du Midi
- Subway
- EXKi Zuid
- Starbucks
- Häagen-Dazs
- Sbarro
- The Coffee Club
- The Belgian Chocolate House
- PAUL
- & many more
- Station has a wide range of facilities for passengers with reduced mobility: elevators and escalators to all platforms, wheelchair lifts and mobile ramps, disabled toilet and parking spaces. Additional assistance can be contacted via the SNCB Mobility Call Center.
- Les Lofts De Styliste
- Park Inn by Radisson Brussels Midi
- Pullman Brussels Centre Midi
- Located in the main concourse and next to the international platforms.
Most popular train connections from Avignon
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