Travel Information
Compare train and bus for Avignon to Frankfurt am Main
Omio recommends booking the train as it is the most popular option from Avignon to Frankfurt am Main among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $93 For those with little time, consider booking a train, which has an average total journey time of 7h 42m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.7kg. Average ticket prices depend on the travel mode: a bus costs an average of $93, while a train costs an average of $220.
Distance: 463 miles (746 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$220 Average price | $93 Average price Cheapest | $246 Average price (fuel + tolls) |
7h 42m Average total duration Fastest 7h 12m Onboard + 30m Additional time* | 15h 28m Average total duration 14h 58m Onboard + 30m Additional time* | 9h 23m Average total duration (door-to-door) |
0.2 - 0.7kg CO2 emissions Lowest | 0.7 - 1.9kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Avignon to Frankfurt am Main
Compare the available ways to get from Avignon to Frankfurt am Main, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Avignon to Frankfurt am Main:
A bus is $128 (€107) less than a train for this route with tickets for a train from Avignon to Frankfurt am Main costing on average $220 (€185).
Other travel options to Frankfurt am Main take longer:
Bus takes on average 15h 28m.
The journey is about 2h 11m faster (7h 12m by train vs 9h 23m by car) and roughly $27 (€23) cheaper once you factor in fuel and tolls ($220 (€185) vs $246 (€207)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Travel optionsfrom Avignon to Frankfurt am Main
How to get from Avignon to Frankfurt am Main by train, bus or flight.
Our recommendation
The best way to travel from Avignon to Frankfurt am Main is by taking a bus because it’s the best combination of price and speed.
5151112:35 AM 13h35 Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle) 2:10 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) $66 1 One-way 0 transfers
Cheapest
5151112:35 AM 13h35 Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle) 2:10 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) $66 1 One-way 0 transfers
Fastest
TGV 9583+
ICE 1067:57 AM 8h22 Avignon TGV 4:19 PM Frankfurt Airport long-distance station $164 1 One-way 1 transfer
Other options
TGV 9583+
ICE 106 · ICE 5767:57 AM 8h43 Avignon TGV 4:40 PM Frankfurt (Main) Hbf $164 1 One-way 2 transfers
6194+
95537:03 AM 10h00 Avignon Centre 5:03 PM Frankfurt (Main) Hbf $262 1 One-way 1 transfer
6106+
95537:41 AM 9h22 Avignon TGV 5:03 PM Frankfurt (Main) Hbf $306 1 One-way 1 transfer
FlixBus · FlixBus+
FlixTrain8:05 PM 19h50 Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle) 3:55 PM Frankfurt South station $107 1 One-way 2 transfers
FlixBus · FlixBus · FlixBus1:55 PM 15h35 Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle) 5:30 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) $112 1 One-way 2 transfers
FlixBus · FlixBus3:25 AM 16h50 Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle) 8:15 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) $114 1 One-way 1 transfer
879337+
9810+
AF7339 · AF101811:11 AM 10h54 Avignon Centre 10:05 PM Frankfurt am Main Airport $332 1 One-way 4 transfers
879337+
9810+
KL1470 · KL182511:11 AM 11h14 Avignon Centre 10:25 PM Frankfurt am Main Airport $347 1 One-way 4 transfers
879337+
9810+
LH2265 · LH12311:11 AM 10h49 Avignon Centre 10:00 PM Frankfurt am Main Airport $924 1 One-way 4 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Avignon to Frankfurt am Main
Travel to Frankfurt am Main easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Avignon to Frankfurt am Main.

This is compared to other travel options from Avignon to Frankfurt am Main:
A bus is $128 (€107) less than a train for this route with tickets for a train from Avignon to Frankfurt am Main costing on average $220 (€185).
Other travel options to Frankfurt am Main take longer:
Bus takes on average 15h 28m.
- Around 11 trains per day.
- Around 7 buses per day.
However, we recommend checking specific travel dates for your route between Avignon and Frankfurt am Main as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Avignon TGV and arrive in Frankfurt (Main) Hbf.
- Buses mostly depart from Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle) and arrive in Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof).
- Flights mostly depart from Lyon Saint Exupery Airport and arrive in Frankfurt am Main Airport.
- Travel with FlixBus, BlaBlaCar Bus, Sindbad to go to Frankfurt am Main by bus.
- Travel with TGV, SNCF | TGV INOUI, SNCF | Intercités de nuit to go to Frankfurt am Main by train.
- 1 direct buses per day with BlaBlaCar Bus, Sindbad.
- 2 direct trains per day with TGV, SNCF | TGV INOUI.
Travelling from Avignon to Frankfurt am Main: related information
Here are some other resources that might have the information you need
