The cheapest and fastest trains from Santa Ana, CA to Indianapolis, IN
Cheapest price
$702
Average price
$702
Fastest journey
2 d 7 h 48 m
Average duration
2 d 7 h 48 m
Trains per day
1
Distance
2887 km
The best way to find a cheap train ticket from Santa Ana, CA to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Ana, CA to Indianapolis, IN will cost around $702 if you buy it on the day, but the cheapest tickets can be found for only $702.
It's difficult to get from Santa Ana, CA to Indianapolis, IN without transferring at least 2 times.


Travel Information
Compare train and bus for Santa Ana, CA to Indianapolis, IN
Omio recommends booking the flight as it is the most popular option from Santa Ana, CA to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from €141. For those with little time consider booking a flight which can get you there in 7h 11m. The ticket price range depends on the travel mode: a bus costs an average of €141, and a flight costs an average of €340.
Distance: 1793 miles (2887 km)
Compare train with
| Train | Most popular Flight | Bus |
|---|---|---|
€241 Average price | €340 Average price | €141 Average price Cheapest |
48h 11m Average total duration 47h 41m Onboard + 30m Additional time* | 10h 11m Average total duration Fastest 7h 11m Onboard + 3h 0m Additional time* | 51h 15m Average total duration 50h 45m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Santa Ana, CA to Indianapolis, IN train times
The table below shows live departures for Santa Ana, CA to Indianapolis, IN trains for tomorrow, Sunday, December 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:01 PM Santa Ana, CA | 55h48 | 11:49 PM Indianapolis, IN | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santa Ana, CA to Indianapolis, IN by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 21
Dec 22
Dec 23
Dec 24
Dec 25
Dec 26
Dec 27
Why should you book Santa Ana to Indianapolis trains with Omio?
Amtrak as well as Metrolink Trains offer trains services from Santa Ana to Indianapolis. Omio is an official ticket reseller for all your travel options from Santa Ana to Indianapolis.
Why book with Omio vs Amtrak?
- Compare with other providers: On Omio, you can not only buy tickets for Amtrak, but also compare tickets for the likes of Metrolink Trains to find the best option for your trip from Santa Ana to Indianapolis.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Amtrak with all available travel options, which are train and bus to ensure you get the best deal for traveling from Santa Ana to Indianapolis.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While Amtrak tickets can be bought on Amtrak's website or third party sellers, Omio allows you to compare with the likes of Metrolink Trains to help you choose the right option for your journey from Santa Ana to Indianapolis.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Santa Ana to Indianapolis.
Journey information
Overview: Train from Santa Ana, CA to Indianapolis, IN
Trains from Santa Ana, CA to Indianapolis, IN run on average 4 times per day, taking around 47h 41m. Cheap train tickets for this journey start at $301 (€241) but you can travel from only $175 (€141) by bus.
The earliest train runs at 06:00, the last at 06:00. The fastest train covers the 1793 miles (2887 km) distance in 47h 41m.
Distance 1793 miles (2887 km) |
Average train duration 47h 41m |
Cheapest ticket price $301 (€241) |
Trains per day 4 |
Fastest train 47h 41m |
First train 06:00 |
Last train 06:00 |
Train companies: Amtrak, Metrolink Trains from Santa Ana, CA to Indianapolis, IN trainsAmtrak, Metrolink Trains trains will get you between Santa Ana, CA and Indianapolis, IN from $175 (€141). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
Metrolink Trains
FAQs: Trains from Santa Ana, CA to Indianapolis, IN
Find answers to the most common questions about traveling from Santa Ana, CA to Indianapolis, IN by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Santa Ana, CA to Indianapolis, IN
- 6:00 AM - 10:00 PM Monday - Sunday
- Parking is available with several spaces for both short-term and long-term parking.
- The Olde Ship British Pub & Restaurant
- Chapter One: the modern local
- Outside the main entrance.
- Ramps.
- $0.50
- DoubleTree by Hilton Santa Ana
- Courtyard by Marriott Santa Ana
- Holiday Inn Santa Ana-Orange County Airport
- Located in the main hall
- Located in the main hall
- Free
- Hall 1: main entrance, ticket office, and waiting area
- Hall 2: platforms for Amtrak and Metrolink services
- Bus: OCTA routes 53, 83, 206
- Train: Amtrak Pacific Surfliner, Metrolink Orange County Line
- 6:00 AM - 11:00 PM Monday - Sunday
- Free
- Parking is available a few blocks away from the station.
- Harry & Izzy's
- St. Elmo Steak House
- Outside the main entrance.
- Ramps.
- Free for passengers
- Crowne Plaza Indianapolis-Dwtn-Union-Stn
- Omni Severin Hotel
- The Westin Indianapolis
- Located in the main hall
- Free
- Hall 1: main entrance, platform for Amtrak's Cardinal line
- Bus: IndyGo routes available nearby
Most popular train connections from Santa Ana, CA
More options for your journey from Santa Ana, CA to Indianapolis, IN
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